Homo sapiens

145 known processes

FOXO3

forkhead box O3

(Aliases: FKHRL1,AF6q21,MGC31925,FOXO2,DKFZp781A0677,FOXO3A,MGC12739,FKHRL1P2)

FOXO3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of feeding behavior GO:2000253 1 0.706
Fly
regulation of activin receptor signaling pathway GO:0032925 14 0.639
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.590
multicellular organismal aging GO:0010259 3 0.312
Fly
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.301
internal protein amino acid acetylation GO:0006475 101 0.292
lipid transport GO:0006869 90 0.249
cellular ketone metabolic process GO:0042180 80 0.240
regulation of cellular ketone metabolic process GO:0010565 50 0.218
single organism carbohydrate metabolic process GO:0044723 193 0.214
Fly
cellular response to dna damage stimulus GO:0006974 379 0.209
Mouse Fly
negative regulation of cell proliferation GO:0008285 228 0.206
Human Fly
regulation of feeding behavior GO:0060259 3 0.204
Fly
positive regulation of autophagy GO:0010508 24 0.201
Human
histone acetylation GO:0016573 93 0.189
carbohydrate metabolic process GO:0005975 207 0.177
Fly
internal peptidyl lysine acetylation GO:0018393 97 0.177
cell cycle arrest GO:0007050 71 0.170
Human
mhc class ii biosynthetic process GO:0045342 4 0.165
glycogen metabolic process GO:0005977 22 0.162
Fly
positive regulation of erythrocyte differentiation GO:0045648 11 0.161
protein catabolic process GO:0030163 325 0.159
Human
regulation of carbohydrate metabolic process GO:0006109 54 0.158
response to glucagon GO:0033762 1 0.155
oogenesis GO:0048477 2 0.151
Mouse
regulation of neural precursor cell proliferation GO:2000177 4 0.143
Mouse
purine ribonucleotide biosynthetic process GO:0009152 79 0.143
Fly
peptidyl lysine modification GO:0018205 144 0.140
histone modification GO:0016570 251 0.136
cellular carbohydrate metabolic process GO:0044262 84 0.136
Fly
cellular glucan metabolic process GO:0006073 22 0.136
Fly
monosaccharide metabolic process GO:0005996 74 0.134
regulation of cellular amine metabolic process GO:0033238 11 0.132
chromatin organization GO:0006325 351 0.131
cellular response to nutrient levels GO:0031669 69 0.130
Human Fly
regulation of smooth muscle cell differentiation GO:0051150 3 0.130
Human
positive regulation of developmental process GO:0051094 314 0.127
lipid localization GO:0010876 106 0.127
Fly
positive regulation of gluconeogenesis GO:0045722 1 0.126
female gamete generation GO:0007292 2 0.124
Mouse
response to oxygen levels GO:0070482 100 0.112
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.112
Fly
camp biosynthetic process GO:0006171 47 0.111
Fly
cellular response to endogenous stimulus GO:0071495 336 0.108
Human Fly
rhythmic behavior GO:0007622 2 0.106
Fly
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.106
negative regulation of cell growth GO:0030308 83 0.105
Fly
post embryonic development GO:0009791 2 0.104
Fly
pituitary gland development GO:0021983 2 0.104
energy reserve metabolic process GO:0006112 22 0.104
Fly
regulation of cell growth GO:0001558 135 0.102
Fly
negative regulation of cell size GO:0045792 3 0.101
Fly
system process GO:0003008 349 0.099
cyclic nucleotide biosynthetic process GO:0009190 61 0.098
Fly
chemical homeostasis GO:0048878 306 0.097
Mouse Fly
regulation of response to external stimulus GO:0032101 222 0.096
Fly
myoblast fusion GO:0007520 1 0.094
Fly
regulation of cytokine production GO:0001817 232 0.092
epithelium development GO:0060429 227 0.091
cellular response to external stimulus GO:0071496 111 0.091
Human Fly
ribose phosphate biosynthetic process GO:0046390 82 0.090
Fly
hexose metabolic process GO:0019318 55 0.090
purine nucleotide biosynthetic process GO:0006164 84 0.090
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.088
Fly
regulation of lipid biosynthetic process GO:0046890 47 0.086
negative regulation of smooth muscle cell differentiation GO:0051151 2 0.086
Human
response to abiotic stimulus GO:0009628 336 0.085
Human
lipid metabolic process GO:0006629 381 0.084
Fly
regulation of lipid metabolic process GO:0019216 96 0.082
Fly
cellular response to nitrogen compound GO:1901699 144 0.082
Human Fly
covalent chromatin modification GO:0016569 254 0.081
response to oxygen containing compound GO:1901700 369 0.081
Human Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.081
regulation of autophagy GO:0010506 52 0.079
Human Fly
cellular polysaccharide metabolic process GO:0044264 27 0.079
Fly
associative learning GO:0008306 1 0.078
regulation of cellular carbohydrate metabolic process GO:0010675 47 0.077
g protein coupled receptor signaling pathway GO:0007186 207 0.077
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.077
Fly
positive regulation of carbohydrate metabolic process GO:0045913 21 0.077
regulation of cell cycle GO:0051726 393 0.075
Human
ribonucleotide biosynthetic process GO:0009260 81 0.075
Fly
negative regulation of catalytic activity GO:0043086 335 0.075
positive regulation of catabolic process GO:0009896 310 0.074
Human
regulation of homeostatic process GO:0032844 121 0.073
regulation of growth GO:0040008 165 0.072
Fly
carbon catabolite activation of transcription GO:0045991 3 0.071
protein acylation GO:0043543 138 0.071
negative regulation of phosphorus metabolic process GO:0010563 267 0.071
Human
erythrocyte differentiation GO:0030218 28 0.070
cellular amine metabolic process GO:0044106 41 0.070
negative regulation of phosphorylation GO:0042326 174 0.069
Human
somatic stem cell maintenance GO:0035019 4 0.069
negative regulation of intracellular signal transduction GO:1902532 183 0.069
Human
determination of adult lifespan GO:0008340 2 0.069
Fly
axon cargo transport GO:0008088 2 0.069
cellular response to starvation GO:0009267 58 0.068
Human Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.068
Human Fly
apoptotic signaling pathway GO:0097190 268 0.067
Mouse
response to nitrogen compound GO:1901698 184 0.066
Human Fly
positive regulation of myeloid cell apoptotic process GO:0033034 2 0.065
syncytium formation by plasma membrane fusion GO:0000768 2 0.065
Fly
positive regulation of neural precursor cell proliferation GO:2000179 2 0.064
regulation of transferase activity GO:0051338 355 0.063
oxidation reduction process GO:0055114 396 0.062
Fly
chromatin modification GO:0016568 298 0.062
nucleotide biosynthetic process GO:0009165 109 0.061
Fly
carbohydrate biosynthetic process GO:0016051 42 0.061
regulation of immune response GO:0050776 201 0.061
organic hydroxy compound transport GO:0015850 63 0.061
embryonic placenta development GO:0001892 1 0.060
regulation of cell cycle process GO:0010564 266 0.060
Human
nervous system development GO:0007399 293 0.060
Zebrafish Fly
regulation of cell differentiation GO:0045595 393 0.060
positive regulation of camp dependent protein kinase activity GO:2000481 4 0.060
n terminal protein amino acid modification GO:0031365 13 0.060
myeloid cell differentiation GO:0030099 117 0.059
positive regulation of cellular catabolic process GO:0031331 284 0.059
Human
cellular response to growth factor stimulus GO:0071363 197 0.058
peptidyl lysine acetylation GO:0018394 101 0.058
cell morphogenesis involved in differentiation GO:0000904 144 0.058
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.058
transmembrane transport GO:0055085 399 0.057
anterior posterior axis specification GO:0009948 2 0.057
lipid catabolic process GO:0016042 84 0.057
segmentation GO:0035282 4 0.056
regulation of glucose metabolic process GO:0010906 28 0.056
organophosphate biosynthetic process GO:0090407 163 0.055
Fly
cellular response to oxygen containing compound GO:1901701 276 0.055
Human Fly
regulation of hormone levels GO:0010817 125 0.055
cell morphogenesis GO:0000902 296 0.055
Fly
regulation of kinase activity GO:0043549 314 0.055
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 3 0.054
histone h4 acetylation GO:0043967 47 0.054
response to uv GO:0009411 73 0.054
somatic muscle development GO:0007525 1 0.054
Fly
protein acetylation GO:0006473 116 0.052
myeloid cell homeostasis GO:0002262 34 0.052
positive regulation of transcription by galactose GO:0000411 1 0.052
negative regulation of protein metabolic process GO:0051248 391 0.052
negative regulation of developmental process GO:0051093 247 0.052
Human Mouse Fly
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.051
positive regulation of programmed cell death GO:0043068 249 0.051
positive regulation of immune system process GO:0002684 283 0.051
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.051
anion transport GO:0006820 161 0.051
sterol transport GO:0015918 39 0.051
positive regulation of apoptotic process GO:0043065 246 0.051
neuroblast proliferation GO:0007405 4 0.051
anatomical structure formation involved in morphogenesis GO:0048646 284 0.050
Human Fly
cellular lipid catabolic process GO:0044242 65 0.050
negative regulation of growth GO:0045926 97 0.050
Fly
response to peptide GO:1901652 65 0.050
Human Fly
lipid biosynthetic process GO:0008610 177 0.050
organic anion transport GO:0015711 103 0.049
cellular response to increased oxygen levels GO:0036295 4 0.049
Human
positive regulation of hormone biosynthetic process GO:0046886 4 0.049
response to hyperoxia GO:0055093 4 0.049
Human
negative regulation of gliogenesis GO:0014014 3 0.048
macroautophagy GO:0016236 39 0.048
Fly
cell aging GO:0007569 52 0.047
immune response GO:0006955 307 0.047
positive regulation of cellular component organization GO:0051130 376 0.047
regulation of fat cell differentiation GO:0045598 23 0.046
cellular response to extracellular stimulus GO:0031668 72 0.046
Human Fly
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.045
Zebrafish Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.045
regulation of protein localization GO:0032880 296 0.045
maintenance of location GO:0051235 112 0.045
Fly
positive regulation of cell differentiation GO:0045597 211 0.045
cellular response to inorganic substance GO:0071241 45 0.045
neuron projection development GO:0031175 106 0.045
Fly
aging GO:0007568 66 0.045
Fly
response to cytokine GO:0034097 232 0.044
epithelial cell differentiation GO:0030855 141 0.043
endodermal cell fate specification GO:0001714 4 0.043
autophagy GO:0006914 88 0.043
Human Fly
response to nitric oxide GO:0071731 4 0.043
regulation of protein kinase activity GO:0045859 289 0.043
positive regulation of myeloid cell differentiation GO:0045639 39 0.043
cellular response to oxygen levels GO:0071453 55 0.043
Human
bile acid metabolic process GO:0008206 14 0.043
fatty acid metabolic process GO:0006631 115 0.042
negative regulation of cell death GO:0060548 345 0.042
Human
positive regulation of immune response GO:0050778 159 0.042
positive regulation of glucose metabolic process GO:0010907 12 0.041
negative regulation of cell fate commitment GO:0010454 3 0.041
regulation of wnt signaling pathway GO:0030111 123 0.041
Zebrafish Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.040
organic hydroxy compound metabolic process GO:1901615 147 0.040
regulation of mapk cascade GO:0043408 262 0.040
Human
hemopoiesis GO:0030097 180 0.040
cell type specific apoptotic process GO:0097285 125 0.040
stem cell division GO:0017145 2 0.040
neural tube formation GO:0001841 3 0.040
negative regulation of apoptotic process GO:0043066 316 0.040
Human
cardiovascular system development GO:0072358 262 0.040
Human
response to hormone GO:0009725 175 0.039
Human Fly
amine metabolic process GO:0009308 44 0.039
hormone transport GO:0009914 68 0.039
glucose metabolic process GO:0006006 45 0.039
cholesterol transport GO:0030301 39 0.039
canonical wnt signaling pathway GO:0060070 116 0.039
Zebrafish Mouse
defense response GO:0006952 315 0.039
cellular component morphogenesis GO:0032989 314 0.039
Fly
fat cell differentiation GO:0045444 32 0.039
immune system development GO:0002520 195 0.039
signal transduction by phosphorylation GO:0023014 297 0.038
Human
mitotic cell cycle process GO:1903047 286 0.038
positive regulation of lipid metabolic process GO:0045834 50 0.038
neutral lipid metabolic process GO:0006638 27 0.038
cell projection organization GO:0030030 252 0.038
Fly
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.038
anatomical structure homeostasis GO:0060249 100 0.038
cellular senescence GO:0090398 34 0.037
positive regulation of cell proliferation GO:0008284 301 0.037
microtubule based process GO:0007017 210 0.037
Fly
regulation of protein catabolic process GO:0042176 155 0.037
Human
neurogenesis GO:0022008 169 0.037
Fly
steroid metabolic process GO:0008202 94 0.037
negative regulation of cell cycle GO:0045786 193 0.037
Human
negative regulation of g0 to g1 transition GO:0070317 2 0.036
Human
cellular response to peptide hormone stimulus GO:0071375 56 0.036
Human Fly
phospholipid catabolic process GO:0009395 12 0.036
positive regulation of hydrolase activity GO:0051345 331 0.035
hematopoietic or lymphoid organ development GO:0048534 186 0.035
positive regulation of lipid biosynthetic process GO:0046889 22 0.035
translation GO:0006412 132 0.035
protein deacetylation GO:0006476 38 0.035
regulation of myeloid cell differentiation GO:0045637 81 0.034
neuron development GO:0048666 113 0.034
Fly
cell growth GO:0016049 160 0.034
Fly
methylation GO:0032259 106 0.034
cellular lipid metabolic process GO:0044255 303 0.033
carboxylic acid transport GO:0046942 63 0.033
locomotory behavior GO:0007626 1 0.033
Fly
regulation of lipid transport GO:0032368 44 0.033
response to decreased oxygen levels GO:0036293 96 0.033
regulation of peptidase activity GO:0052547 180 0.033
stem cell differentiation GO:0048863 93 0.033
Human Mouse Fly
response to light stimulus GO:0009416 87 0.033
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.033
cellular response to reactive oxygen species GO:0034614 50 0.033
establishment of protein localization to organelle GO:0072594 172 0.033
positive regulation of cellular response to insulin stimulus GO:1900078 6 0.033
Fly
regulation of lipid catabolic process GO:0050994 23 0.033
cell cycle phase transition GO:0044770 173 0.032
glycerolipid metabolic process GO:0046486 107 0.032
skin development GO:0043588 76 0.032
cellular response to hormone stimulus GO:0032870 125 0.032
Human Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.032
Human
oocyte development GO:0048599 1 0.032
Mouse
regulation of proteolysis GO:0030162 293 0.031
small molecule catabolic process GO:0044282 92 0.031
positive regulation of cellular carbohydrate metabolic process GO:0010676 16 0.031
energy derivation by oxidation of organic compounds GO:0015980 43 0.031
Fly
regulation of apoptotic signaling pathway GO:2001233 175 0.031
monocarboxylic acid metabolic process GO:0032787 185 0.031
camp metabolic process GO:0046058 61 0.031
Fly
organ induction GO:0001759 4 0.031
mitotic cell cycle GO:0000278 326 0.031
intracellular protein transport GO:0006886 270 0.031
cellular homeostasis GO:0019725 196 0.031
regulation of canonical wnt signaling pathway GO:0060828 88 0.030
Zebrafish Mouse
positive regulation of peptidase activity GO:0010952 88 0.030
negative regulation of cell differentiation GO:0045596 171 0.030
Human Mouse Fly
glycoprotein biosynthetic process GO:0009101 91 0.029
histone h3 acetylation GO:0043966 45 0.029
ion transmembrane transport GO:0034220 338 0.029
regulation of transcription by galactose GO:0000409 1 0.029
forelimb morphogenesis GO:0035136 4 0.029
positive regulation of cholesterol storage GO:0010886 4 0.029
hindbrain development GO:0030902 3 0.029
organic acid catabolic process GO:0016054 71 0.029
positive regulation of cell cycle GO:0045787 140 0.029
cytoplasmic transport GO:0016482 379 0.028
regulation of endopeptidase activity GO:0052548 170 0.028
positive regulation of secretion GO:0051047 116 0.028
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.028
neuron differentiation GO:0030182 138 0.028
Fly
regulation of heart morphogenesis GO:2000826 4 0.028
regulation of tor signaling GO:0032006 30 0.028
neuronal stem cell maintenance GO:0097150 5 0.028
Mouse
response to bacterium GO:0009617 144 0.028
Fly
negative regulation of phosphate metabolic process GO:0045936 267 0.028
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
positive regulation of cell migration GO:0030335 172 0.027
epidermis morphogenesis GO:0048730 3 0.027
response to low density lipoprotein particle GO:0055098 4 0.027
neurological system process GO:0050877 163 0.027
positive regulation of cell death GO:0010942 263 0.027
small molecule biosynthetic process GO:0044283 157 0.027
negative regulation of protein modification process GO:0031400 200 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.027
gastrulation with mouth forming second GO:0001702 1 0.027
n terminal peptidyl lysine acetylation GO:0018076 4 0.027
response to organic cyclic compound GO:0014070 204 0.027
regulation of alkaline phosphatase activity GO:0010692 2 0.027
regulation of transcription by chromatin organization GO:0034401 1 0.027
protein import GO:0017038 130 0.026
regulation of protein stability GO:0031647 87 0.026
cellular response to organonitrogen compound GO:0071417 124 0.026
Human Fly
response to organonitrogen compound GO:0010243 156 0.026
Human Fly
regulation of g0 to g1 transition GO:0070316 2 0.026
Human
negative regulation of angiogenesis GO:0016525 39 0.026
Human
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.026
cholesterol efflux GO:0033344 28 0.025
positive regulation of protein catabolic process GO:0045732 75 0.025
Human
growth GO:0040007 202 0.025
Mouse Fly
protein localization to organelle GO:0033365 280 0.025
visual learning GO:0008542 1 0.025
protein modification by small protein removal GO:0070646 92 0.025
triglyceride metabolic process GO:0006641 23 0.025
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.025
response to drug GO:0042493 81 0.025
blood vessel morphogenesis GO:0048514 162 0.025
Human
negative regulation of transferase activity GO:0051348 124 0.025
axon regeneration GO:0031103 1 0.025
protein localization to nucleus GO:0034504 136 0.024
response to other organism GO:0051707 261 0.024
Fly
regulation of cellular response to stress GO:0080135 244 0.024
Human Fly
regulation of system process GO:0044057 101 0.024
cell proliferation in forebrain GO:0021846 1 0.024
positive regulation of neuroblast proliferation GO:0002052 2 0.024
negative regulation of cellular amine metabolic process GO:0033239 3 0.024
positive regulation of organic acid transport GO:0032892 3 0.024
regulation of vasculature development GO:1901342 97 0.024
Human
response to radiation GO:0009314 151 0.024
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.024
protein targeting GO:0006605 187 0.024
positive regulation of mhc class ii biosynthetic process GO:0045348 3 0.024
positive regulation of neuron apoptotic process GO:0043525 8 0.024
regulation of secretion GO:0051046 194 0.024
microtubule cytoskeleton organization GO:0000226 176 0.024
Fly
protein deubiquitination GO:0016579 79 0.024
single organism cellular localization GO:1902580 332 0.023
tube development GO:0035295 125 0.023
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
adaptive immune response GO:0002250 49 0.023
gland development GO:0048732 48 0.023
somitogenesis GO:0001756 2 0.023
negative regulation of wnt signaling pathway GO:0030178 69 0.023
Zebrafish Mouse
steroid biosynthetic process GO:0006694 46 0.023
dicarboxylic acid biosynthetic process GO:0043650 4 0.023
embryonic epithelial tube formation GO:0001838 4 0.023
response to inorganic substance GO:0010035 127 0.023
secretion by cell GO:0032940 226 0.023
regulation of mesoderm development GO:2000380 4 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.023
regulation of cellular component size GO:0032535 82 0.023
Fly
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.023
cellular response to cytokine stimulus GO:0071345 181 0.023
behavior GO:0007610 112 0.022
Fly
sterol homeostasis GO:0055092 28 0.022
negative regulation of immune system process GO:0002683 136 0.022
tripartite regional subdivision GO:0007351 2 0.022
cell activation GO:0001775 213 0.022
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.022
negative regulation of protein phosphorylation GO:0001933 140 0.022
dna repair GO:0006281 198 0.022
cell projection morphogenesis GO:0048858 129 0.022
Fly
neuromuscular junction development GO:0007528 3 0.022
tor signaling GO:0031929 39 0.022
organic acid transport GO:0015849 65 0.022
asymmetric stem cell division GO:0098722 1 0.022
response to extracellular stimulus GO:0009991 85 0.022
Human Fly
nephron tubule formation GO:0072079 1 0.022
protein processing GO:0016485 226 0.022
embryonic forelimb morphogenesis GO:0035115 4 0.022
response to biotic stimulus GO:0009607 276 0.022
Fly
regulation of multi organism process GO:0043900 157 0.022
peptidyl serine modification GO:0018209 106 0.022
positive regulation of proteolysis GO:0045862 142 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.021
Human Fly
cell part morphogenesis GO:0032990 137 0.021
Fly
reactive oxygen species metabolic process GO:0072593 75 0.021
Mouse
pericardium development GO:0060039 2 0.021
regulation of lymphocyte proliferation GO:0050670 64 0.021
negative regulation of kinase activity GO:0033673 106 0.021
neural crest cell development GO:0014032 3 0.021
negative regulation of glial cell proliferation GO:0060253 2 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
lung cell differentiation GO:0060479 1 0.021
positive regulation of cell cycle process GO:0090068 106 0.021
cellular response to abiotic stimulus GO:0071214 117 0.021
regulation of cellular response to insulin stimulus GO:1900076 17 0.021
Fly
regulation of anatomical structure size GO:0090066 101 0.021
Fly
regulation of ion transport GO:0043269 189 0.021
negative regulation of catabolic process GO:0009895 104 0.021
response to hypoxia GO:0001666 96 0.021
visual behavior GO:0007632 2 0.021
lung saccule development GO:0060430 2 0.020
circulatory system process GO:0003013 113 0.020
lung alveolus development GO:0048286 4 0.020
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter GO:0035947 1 0.020
endomembrane system organization GO:0010256 196 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.020
Human Fly
rna processing GO:0006396 255 0.020
inner ear morphogenesis GO:0042472 4 0.020
erythrocyte homeostasis GO:0034101 31 0.020
response to growth factor GO:0070848 205 0.020
blastoderm segmentation GO:0007350 2 0.020
cation homeostasis GO:0055080 189 0.020
cell migration involved in gastrulation GO:0042074 1 0.020
myotube differentiation GO:0014902 22 0.020
Fly
cellular response to oxidative stress GO:0034599 85 0.020
Mouse Fly
lymphocyte activation GO:0046649 133 0.020
cytokine production GO:0001816 247 0.020
dephosphorylation GO:0016311 209 0.020
cellular response to hyperoxia GO:0071455 4 0.020
Human
negative regulation of interferon beta production GO:0032688 4 0.019
hindlimb morphogenesis GO:0035137 2 0.019
positive regulation of organ growth GO:0046622 2 0.019
respiratory tube development GO:0030323 20 0.019
secretion GO:0046903 254 0.019
rna splicing GO:0008380 131 0.019
angiogenesis GO:0001525 147 0.019
Human
activin receptor signaling pathway GO:0032924 24 0.019
Fly
homeostasis of number of cells GO:0048872 40 0.019
regulation of hormone secretion GO:0046883 57 0.019
regulation of interferon beta biosynthetic process GO:0045357 4 0.019
epidermal cell differentiation GO:0009913 45 0.019
organic acid biosynthetic process GO:0016053 97 0.019
neuroendocrine cell differentiation GO:0061101 2 0.019
regulation of cysteine type endopeptidase activity GO:2000116 127 0.019
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.019
organelle fission GO:0048285 149 0.019
regulation of muscle cell differentiation GO:0051147 31 0.019
Human
negative regulation of hydrolase activity GO:0051346 182 0.019
transforming growth factor beta production GO:0071604 14 0.019
negative regulation of lipid transport GO:0032369 18 0.019
cellular response to hydrogen peroxide GO:0070301 37 0.019
regulation of macroautophagy GO:0016241 19 0.019
Fly
nitrogen cycle metabolic process GO:0071941 3 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
regulation of carbohydrate biosynthetic process GO:0043255 27 0.019
metal ion transport GO:0030001 272 0.019
cellular response to lipid GO:0071396 127 0.019
anterior posterior axis specification embryo GO:0008595 2 0.019
cellular amino acid metabolic process GO:0006520 116 0.019
male genitalia development GO:0030539 1 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
tissue regeneration GO:0042246 3 0.018
mrna metabolic process GO:0016071 175 0.018
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.018
monocarboxylic acid biosynthetic process GO:0072330 67 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.018
negative regulation of t cell apoptotic process GO:0070233 4 0.018
glycoprotein metabolic process GO:0009100 110 0.018
lipid oxidation GO:0034440 33 0.018
alcohol metabolic process GO:0006066 114 0.018
regulation of cardioblast differentiation GO:0051890 4 0.018
proteasomal protein catabolic process GO:0010498 176 0.018
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.018
Fly
i kappab kinase nf kappab signaling GO:0007249 166 0.018
cholesterol homeostasis GO:0042632 28 0.018
cation transport GO:0006812 331 0.018
protein maturation GO:0051604 233 0.018
regulation of glial cell proliferation GO:0060251 4 0.018
mammary gland morphogenesis GO:0060443 2 0.018
cell development GO:0048468 328 0.018
Mouse Fly
negative regulation of apoptotic signaling pathway GO:2001234 97 0.018
negative regulation of oxidative stress induced cell death GO:1903202 17 0.018
epidermis development GO:0008544 59 0.018
response to wounding GO:0009611 168 0.018
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.018
response to lipid GO:0033993 206 0.018
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.017
regulation of heart induction GO:0090381 2 0.017
glucose homeostasis GO:0042593 31 0.017
Mouse Fly
positive regulation of triglyceride metabolic process GO:0090208 9 0.017
forebrain generation of neurons GO:0021872 3 0.017
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.017
cellular response to reactive nitrogen species GO:1902170 2 0.017
lens development in camera type eye GO:0002088 2 0.017
response to acid chemical GO:0001101 66 0.017
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.017
anion transmembrane transport GO:0098656 76 0.017
regulation of reactive oxygen species metabolic process GO:2000377 41 0.017
Mouse

FOXO3 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.310
Human
cancer DOID:162 167 0.268
Human
disease of metabolism DOID:0014667 295 0.069
organ system cancer DOID:0050686 164 0.061
Human
bone disease DOID:0080001 88 0.029
musculoskeletal system disease DOID:17 223 0.029
connective tissue disease DOID:65 109 0.029
acquired metabolic disease DOID:0060158 58 0.024
inherited metabolic disorder DOID:655 242 0.019
bone development disease DOID:0080006 55 0.018
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.017
nervous system disease DOID:863 431 0.017
eye disease DOID:5614 149 0.017