|
|
negative regulation of voltage gated calcium channel activity
|
GO:1901386 |
4 |
1.000
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.996
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.995
|
Human Mouse Fly |
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.987
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.981
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.979
|
Fly |
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.978
|
Fly |
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.966
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.959
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.959
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.955
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.953
|
Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.950
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.947
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.944
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.929
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.923
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.904
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.893
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.883
|
Human |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.871
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.870
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.869
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.862
|
Human |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.860
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.853
|
Human |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.852
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.840
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.835
|
Human |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.833
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.828
|
Fly |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.827
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.821
|
Human |
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.806
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.803
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.787
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.782
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.768
|
Human |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.767
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.765
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.764
|
|
|
|
striated muscle cell apoptotic process
|
GO:0010658 |
3 |
0.752
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.751
|
Human |
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.742
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.740
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.738
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.736
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.726
|
Human |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.711
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.703
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.681
|
Human Fly |
|
|
regulation of calcium ion transmembrane transport
|
GO:1903169 |
28 |
0.679
|
|
|
|
negative regulation of ion transmembrane transporter activity
|
GO:0032413 |
19 |
0.677
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.653
|
|
|
|
regulation of calcium ion transmembrane transporter activity
|
GO:1901019 |
28 |
0.652
|
|
|
|
transposition rna mediated
|
GO:0032197 |
0 |
0.643
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.639
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.633
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.633
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.629
|
Human |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.628
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.615
|
Human |
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.614
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.603
|
Human |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.603
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.601
|
Human |
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.600
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.590
|
Human |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.585
|
Human |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.580
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.572
|
Human |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.572
|
Human |
|
|
neurological system process
|
GO:0050877 |
163 |
0.572
|
Human Fly |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.571
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.566
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.564
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.555
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.543
|
Human |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.541
|
Human |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.509
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.507
|
Human |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.505
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.502
|
Fly |
|
|
blood circulation
|
GO:0008015 |
113 |
0.481
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.476
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.457
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.440
|
Human |
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.431
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.428
|
|
|
|
negative regulation of calcium ion transmembrane transport
|
GO:1903170 |
11 |
0.426
|
|
|
|
regulation of voltage gated calcium channel activity
|
GO:1901385 |
7 |
0.425
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.423
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.421
|
Human |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.417
|
Human |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.413
|
|
|
|
negative regulation of cation channel activity
|
GO:2001258 |
12 |
0.412
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.409
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.408
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.400
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.400
|
Fly |
|
|
single fertilization
|
GO:0007338 |
11 |
0.397
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.389
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.384
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.372
|
Fly |
|
|
sensory perception of taste
|
GO:0050909 |
36 |
0.368
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.362
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.362
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.361
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.359
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.354
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.351
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.348
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.346
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.344
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.344
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.332
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.325
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.325
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.316
|
Human |
|
|
heart development
|
GO:0007507 |
95 |
0.309
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.297
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.296
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.296
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
33 |
0.295
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.291
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.289
|
Human |
|
|
cellular defense response
|
GO:0006968 |
2 |
0.279
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.277
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.275
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.274
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.272
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.272
|
|
|
|
head development
|
GO:0060322 |
108 |
0.270
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.265
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.264
|
Worm |
|
|
regulation of transposition
|
GO:0010528 |
7 |
0.264
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.262
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.261
|
Human |
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.261
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.260
|
Worm |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.258
|
Worm Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.255
|
Fly |
|
|
heart contraction
|
GO:0060047 |
62 |
0.254
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.244
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.240
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.238
|
|
|
|
negative regulation of calcium ion transport
|
GO:0051926 |
19 |
0.238
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.234
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.231
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.230
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.222
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.220
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.218
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.217
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.215
|
Human Mouse |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.214
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.210
|
Fly |
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.209
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.207
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.204
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
10 |
0.204
|
|
|
|
fertilization
|
GO:0009566 |
12 |
0.203
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.200
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.196
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.192
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.184
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.183
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.181
|
Fly |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.181
|
Human |
|
|
positive regulation of blood pressure
|
GO:0045777 |
3 |
0.179
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.178
|
Worm Fly |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.178
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.174
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.170
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.169
|
Worm Fly |
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.169
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.164
|
Human |
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
8 |
0.162
|
Worm |
|
|
chemokine c c motif ligand 11 production
|
GO:0071954 |
1 |
0.160
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.160
|
Human Worm Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.158
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.158
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.156
|
Worm |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.154
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.150
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
7 |
0.149
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.147
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.147
|
Human |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.146
|
Worm Fly |
|
|
circulatory system process
|
GO:0003013 |
113 |
0.143
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.139
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.137
|
Human |
|
|
leukotriene metabolic process
|
GO:0006691 |
10 |
0.136
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.132
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.129
|
|
|
|
negative regulation of calcium ion transmembrane transporter activity
|
GO:1901020 |
11 |
0.129
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.128
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.127
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.127
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.127
|
|
|
|
actin filament capping
|
GO:0051693 |
4 |
0.124
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.121
|
Human |
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.121
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.119
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.118
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.118
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.115
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.114
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.114
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.111
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.111
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.111
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.110
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.110
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.109
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.109
|
Worm Fly |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.109
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.109
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.104
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.104
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.104
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.103
|
Human |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.100
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.098
|
|
|
|
regulation of actin filament depolymerization
|
GO:0030834 |
10 |
0.098
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.097
|
Human |
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.096
|
Fly |
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.093
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.092
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.092
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.091
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.091
|
|
|
|
chemokine c c motif ligand 21 signaling pathway
|
GO:0038116 |
1 |
0.090
|
|
|
|
regulation of respiratory burst
|
GO:0060263 |
8 |
0.090
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.090
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.089
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.088
|
Fly |
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.088
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.087
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.086
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.086
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.084
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.084
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
16 |
0.084
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.083
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.083
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.083
|
Human |
|
|
organelle localization
|
GO:0051640 |
84 |
0.083
|
Worm Fly |
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.082
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.082
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.082
|
Human |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.082
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.081
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.080
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.080
|
Human |
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.080
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.078
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.078
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.077
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.077
|
|
|
|
regulation of filopodium assembly
|
GO:0051489 |
13 |
0.076
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.076
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.076
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.074
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.074
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.074
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.072
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.072
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.072
|
Human |
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.072
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.070
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.070
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.069
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.068
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.068
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.068
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.068
|
Human |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.067
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.066
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.065
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.065
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.065
|
Human |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.064
|
Worm |
|
|
neuron development
|
GO:0048666 |
113 |
0.064
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.062
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.062
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.062
|
Human |
|
|
positive regulation of astrocyte chemotaxis
|
GO:2000464 |
1 |
0.062
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.061
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.061
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.061
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.060
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.060
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.060
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.060
|
Fly |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.059
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.059
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.058
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.057
|
Human |
|
|
transposition
|
GO:0032196 |
8 |
0.057
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.056
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.056
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.056
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.056
|
Human |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.056
|
|
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.056
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.056
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.055
|
Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.055
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.054
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.054
|
|
|
|
superoxide anion generation
|
GO:0042554 |
11 |
0.054
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.053
|
Human |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.053
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.052
|
Worm |
|
|
endocytosis
|
GO:0006897 |
159 |
0.052
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.052
|
Human Fly |
|
|
regulation of astrocyte chemotaxis
|
GO:2000458 |
1 |
0.051
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.051
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.051
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.050
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
9 |
0.050
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.049
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.048
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.048
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.048
|
|
|
|
interleukin 8 mediated signaling pathway
|
GO:0038112 |
2 |
0.048
|
|
|
|
cardiac muscle cell apoptotic process
|
GO:0010659 |
3 |
0.048
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
10 |
0.047
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.047
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.047
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.047
|
Human |
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.047
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.046
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.046
|
Mouse |
|
|
memory
|
GO:0007613 |
3 |
0.046
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.046
|
Human |
|
|
cortical actin cytoskeleton organization
|
GO:0030866 |
9 |
0.046
|
Fly |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.045
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.045
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.045
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.045
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.044
|
|
|
|
mating
|
GO:0007618 |
1 |
0.044
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.044
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.044
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.043
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.043
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.043
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.043
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.042
|
Human |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.042
|
Human |
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.042
|
|
|
|
embryonic axis specification
|
GO:0000578 |
5 |
0.042
|
Worm |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.041
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.041
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.041
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.041
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.041
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.041
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.040
|
Human |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.040
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.039
|
Human |
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.039
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.039
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.039
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.039
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.039
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.039
|
Fly |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.038
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.038
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.037
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.037
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.037
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.036
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.036
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.036
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.036
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.036
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.036
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.035
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.035
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.035
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.035
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.035
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.035
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.034
|
|
|
|
apical junction assembly
|
GO:0043297 |
19 |
0.034
|
Fly |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.034
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.034
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.034
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.033
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.033
|
Human |
|
|
muscle cell apoptotic process
|
GO:0010657 |
11 |
0.033
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.033
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.033
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.032
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.032
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.032
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.031
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
7 |
0.031
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.031
|
|
|
|
astrocyte chemotaxis
|
GO:0035700 |
1 |
0.031
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.031
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.031
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.030
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.030
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.030
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.030
|
Human |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.030
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.030
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.030
|
|
|
|
glucose transport
|
GO:0015758 |
30 |
0.030
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
22 |
0.030
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.030
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.029
|
|
|
|
barbed end actin filament capping
|
GO:0051016 |
3 |
0.029
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.029
|
Human Mouse |
|
|
vacuole organization
|
GO:0007033 |
44 |
0.029
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.029
|
Human |
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.029
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.029
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.029
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.028
|
Human |
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.028
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.028
|
Human |
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.028
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.028
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.028
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.028
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.028
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.028
|
|
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.028
|
Fly |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.028
|
|
|
|
regulation of catagen
|
GO:0051794 |
3 |
0.027
|
|
|
|
regulation of release of sequestered calcium ion into cytosol
|
GO:0051279 |
27 |
0.027
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.027
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.027
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.027
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.026
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.026
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.026
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.026
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.026
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.026
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.026
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.025
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.025
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.025
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.025
|
Human |
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.025
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.025
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.025
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.025
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.024
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.024
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.024
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.024
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.024
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.024
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.024
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.024
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.024
|
Fly |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.024
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.024
|
|
|
|
neutrophil mediated killing of bacterium
|
GO:0070944 |
1 |
0.023
|
|
|
|
regulation of glucose import
|
GO:0046324 |
21 |
0.023
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.023
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.023
|
Human Fly |
|
|
retina development in camera type eye
|
GO:0060041 |
15 |
0.023
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.023
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.023
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.023
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.023
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.023
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.023
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.023
|
Human |
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.023
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.022
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.022
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.022
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.022
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.022
|
Human |
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.022
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.022
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.022
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.022
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
10 |
0.022
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.022
|
|
