IMP
Process View
cardiac muscle cell apoptotic process
A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "cardiac muscle cell apoptotic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TBX5 | T-box 5 | 0.680 | ||
| INSR | insulin receptor | 0.319 | Human | |
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.271 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.216 | ||
| IRS1 | insulin receptor substrate 1 | 0.173 | ||
| EGFR | epidermal growth factor receptor | 0.119 | ||
| EPOR | erythropoietin receptor | 0.111 | ||
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.095 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.079 | ||
| SIRT3 | sirtuin 3 | 0.078 | ||
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.061 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.056 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.054 | Human | |
| BLOC1S2 | biogenesis of lysosomal organelles complex-1, subunit 2 | 0.051 | ||
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.048 | ||
| IRS2 | insulin receptor substrate 2 | 0.045 | ||
| PAX8 | paired box 8 | 0.043 | ||
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.039 | ||
| GRIA4 | glutamate receptor, ionotrophic, AMPA 4 | 0.035 | ||
| GHR | growth hormone receptor | 0.035 | ||
| SH2B1 | SH2B adaptor protein 1 | 0.035 | ||
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | 0.035 | ||
| PARVA | parvin, alpha | 0.033 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.032 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.030 | ||
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.028 | ||
| PARVB | parvin, beta | 0.027 | ||
| GATA4 | GATA binding protein 4 | 0.026 | ||
| STAT5B | signal transducer and activator of transcription 5B | 0.025 | ||
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.022 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.021 | ||
| LAT | linker for activation of T cells | 0.021 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.020 | ||
| C1orf93 | chromosome 1 open reading frame 93 | 0.020 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.018 | ||
| ZNF746 | zinc finger protein 746 | 0.017 | ||
| GRB14 | growth factor receptor-bound protein 14 | 0.017 | ||
| HTT | huntingtin | 0.017 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.017 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.017 | ||
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.016 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.016 | ||
| CSK | c-src tyrosine kinase | 0.015 | ||
| GOLT1B | golgi transport 1B | 0.015 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.015 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.015 | ||
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.013 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.013 | ||
| BCR | breakpoint cluster region | 0.013 | ||
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.013 | ||
| RSU1 | Ras suppressor protein 1 | 0.013 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.013 | ||
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.013 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.012 | ||
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.012 | ||
| DUSP23 | dual specificity phosphatase 23 | 0.012 | ||
| TMEM33 | transmembrane protein 33 | 0.012 | ||
| GORAB | golgin, RAB6-interacting | 0.012 | ||
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.012 | ||
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.012 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.012 | ||
| C15orf29 | chromosome 15 open reading frame 29 | 0.011 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.011 | ||
| UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 0.011 | ||
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | 0.011 | ||
| NEUROG3 | neurogenin 3 | 0.011 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.011 | ||
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.011 | ||
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | 0.011 | ||
| GYG1 | glycogenin 1 | 0.011 | ||
| ZNF133 | zinc finger protein 133 | 0.011 | ||
| SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 0.011 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.010 | ||
| PRKCA | protein kinase C, alpha | 0.010 | ||
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.010 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.010 | ||
| DPH3 | DPH3, KTI11 homolog (S. cerevisiae) | 0.010 | ||
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.010 | ||
| JAK3 | Janus kinase 3 | 0.010 | ||
| CALCA | calcitonin-related polypeptide alpha | 0.010 |