Homo sapiens

0 known processes

HLA-DRB4

major histocompatibility complex, class II, DR beta 4

(Aliases: DR-13,DR-14,DR14,DR13,DRB4,HLA-DR4B)

HLA-DRB4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dendritic cell antigen processing and presentation GO:0002468 1 0.868
cytokine production GO:0001816 247 0.621
peptide antigen assembly with mhc protein complex GO:0002501 4 0.410
negative regulation of antigen processing and presentation GO:0002578 5 0.374
regulation of cytokine production GO:0001817 232 0.365
peptide secretion GO:0002790 51 0.365
defense response GO:0006952 315 0.346
detection of external biotic stimulus GO:0098581 19 0.336
regulation of interleukin 10 secretion GO:2001179 4 0.336
regulation of leukocyte activation GO:0002694 115 0.330
negative regulation of cell proliferation GO:0008285 228 0.329
cellular amino acid metabolic process GO:0006520 116 0.312
cellular macromolecular complex assembly GO:0034622 324 0.286
positive regulation of cellular amine metabolic process GO:0033240 7 0.273
lymphocyte proliferation GO:0046651 70 0.272
detection of biotic stimulus GO:0009595 21 0.268
secretion GO:0046903 254 0.268
regulation of lymphocyte proliferation GO:0050670 64 0.260
immune response GO:0006955 307 0.258
positive regulation of immune system process GO:0002684 283 0.256
positive regulation of transport GO:0051050 336 0.248
cell activation GO:0001775 213 0.245
regulation of leukocyte proliferation GO:0070663 67 0.238
response to cytokine GO:0034097 232 0.223
cellular amine metabolic process GO:0044106 41 0.222
t cell activation GO:0042110 99 0.217
antigen processing and presentation GO:0019882 33 0.214
regulation of t cell activation GO:0050863 77 0.214
regulation of t cell proliferation GO:0042129 42 0.212
regulation of cell activation GO:0050865 125 0.211
positive regulation of immune response GO:0050778 159 0.204
negative regulation of immune response GO:0050777 40 0.204
cellular protein complex assembly GO:0043623 188 0.203
cellular response to oxygen containing compound GO:1901701 276 0.201
regulation of protein secretion GO:0050708 86 0.200
peptide transport GO:0015833 74 0.199
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.195
innate immune response GO:0045087 178 0.193
positive regulation of homeostatic process GO:0032846 47 0.192
hormone secretion GO:0046879 65 0.188
cellular response to interferon gamma GO:0071346 24 0.187
positive regulation of secretion GO:0051047 116 0.184
cellular homeostasis GO:0019725 196 0.182
mononuclear cell proliferation GO:0032943 71 0.182
cellular lipid metabolic process GO:0044255 303 0.182
response to oxygen containing compound GO:1901700 369 0.181
secretion by cell GO:0032940 226 0.178
regulation of response to wounding GO:1903034 101 0.177
regulation of hormone secretion GO:0046883 57 0.176
negative regulation of multicellular organismal process GO:0051241 317 0.176
protein secretion GO:0009306 98 0.176
response to biotic stimulus GO:0009607 276 0.173
regulation of protein transport GO:0051223 213 0.172
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.172
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.170
regulation of interferon gamma production GO:0032649 36 0.168
lymphocyte activation GO:0046649 133 0.168
system process GO:0003008 349 0.168
peptide antigen assembly with mhc class ii protein complex GO:0002503 4 0.168
regulation of secretion by cell GO:1903530 177 0.168
protein oligomerization GO:0051259 173 0.166
inflammatory response GO:0006954 79 0.165
regulation of hormone levels GO:0010817 125 0.164
response to bacterium GO:0009617 144 0.162
regulation of defense response GO:0031347 154 0.160
positive regulation of lymphocyte activation GO:0051251 73 0.157
regulation of secretion GO:0051046 194 0.157
leukocyte activation GO:0045321 164 0.156
taxis GO:0042330 157 0.153
negative regulation of cytokine production GO:0001818 82 0.152
regulation of cellular ketone metabolic process GO:0010565 50 0.152
regulation of cell migration GO:0030334 289 0.152
positive regulation of lymphocyte proliferation GO:0050671 46 0.150
lymphocyte mediated immunity GO:0002449 48 0.150
response to external biotic stimulus GO:0043207 261 0.149
regulation of mononuclear cell proliferation GO:0032944 65 0.149
response to other organism GO:0051707 261 0.148
cellular chemical homeostasis GO:0055082 180 0.147
regulation of protein localization GO:0032880 296 0.147
signal release GO:0023061 70 0.139
negative regulation of immune system process GO:0002683 136 0.138
humoral immune response GO:0006959 49 0.138
positive regulation of t cell proliferation GO:0042102 33 0.137
antigen processing and presentation of peptide antigen GO:0048002 18 0.137
regulation of lymphocyte activation GO:0051249 103 0.136
negative regulation of response to external stimulus GO:0032102 83 0.135
regulation of behavior GO:0050795 82 0.135
regulation of establishment of protein localization GO:0070201 242 0.135
positive regulation of cell activation GO:0050867 81 0.130
positive regulation of leukocyte proliferation GO:0070665 48 0.128
regulation of homeostatic process GO:0032844 121 0.128
regulation of peptide hormone secretion GO:0090276 41 0.126
nitrogen compound transport GO:0071705 191 0.118
regulation of response to external stimulus GO:0032101 222 0.118
cytokine secretion GO:0050663 64 0.117
leukocyte migration GO:0050900 107 0.116
detection of stimulus GO:0051606 85 0.113
hormone transport GO:0009914 68 0.110
protein maturation GO:0051604 233 0.108
immune effector process GO:0002252 159 0.108
positive regulation of leukocyte activation GO:0002696 80 0.108
positive regulation of macrophage chemotaxis GO:0010759 3 0.105
hematopoietic or lymphoid organ development GO:0048534 186 0.103
regulation of cytokine secretion GO:0050707 57 0.103
leukocyte proliferation GO:0070661 74 0.101
peptide hormone secretion GO:0030072 50 0.100
t cell proliferation GO:0042098 45 0.099
regulation of immune response GO:0050776 201 0.098
leukocyte mediated immunity GO:0002443 59 0.097
positive regulation of protein kinase activity GO:0045860 190 0.097
cellular ketone metabolic process GO:0042180 80 0.095
amine metabolic process GO:0009308 44 0.093
cellular response to cytokine stimulus GO:0071345 181 0.092
negative regulation of t cell proliferation GO:0042130 8 0.091
cation transport GO:0006812 331 0.090
regulation of macrophage chemotaxis GO:0010758 4 0.087
ras protein signal transduction GO:0007265 73 0.087
regulation of cellular amine metabolic process GO:0033238 11 0.087
regulation of cellular amino acid metabolic process GO:0006521 6 0.084
interleukin 10 production GO:0032613 17 0.083
amide transport GO:0042886 76 0.082
interferon gamma production GO:0032609 39 0.081
response to wounding GO:0009611 168 0.079
inflammatory response to antigenic stimulus GO:0002437 4 0.078
negative regulation of defense response GO:0031348 47 0.077
adaptive immune response GO:0002250 49 0.075
response to interferon gamma GO:0034341 39 0.074
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.074
lipid metabolic process GO:0006629 381 0.074
negative regulation of response to wounding GO:1903035 47 0.073
cellular response to ammonium ion GO:0071242 4 0.073
protein tetramerization GO:0051262 47 0.072
hemopoiesis GO:0030097 180 0.072
regulation of insulin secretion GO:0050796 33 0.072
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.072
cellular response to endogenous stimulus GO:0071495 336 0.070
neurological system process GO:0050877 163 0.069
biological adhesion GO:0022610 331 0.068
negative regulation of t cell cytokine production GO:0002725 4 0.067
positive regulation of cytokine production GO:0001819 167 0.067
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.067
regulation of cell motility GO:2000145 299 0.066
negative regulation of t cell activation GO:0050868 18 0.065
t helper 1 type immune response GO:0042088 8 0.065
glial cell migration GO:0008347 4 0.065
regulation of inflammatory response GO:0050727 46 0.064
negative regulation of mononuclear cell proliferation GO:0032945 15 0.064
cell adhesion GO:0007155 325 0.063
mhc class ii protein complex assembly GO:0002399 4 0.061
positive regulation of mononuclear cell proliferation GO:0032946 47 0.061
regulation of locomotion GO:0040012 329 0.060
regulation of chemotaxis GO:0050920 74 0.060
immune system development GO:0002520 195 0.060
positive regulation of response to external stimulus GO:0032103 88 0.058
positive regulation of cell proliferation GO:0008284 301 0.058
mapk cascade GO:0000165 288 0.058
regulation of peptide transport GO:0090087 62 0.057
post embryonic development GO:0009791 2 0.056
eosinophil activation involved in immune response GO:0002278 2 0.055
negative regulation of cell death GO:0060548 345 0.055
insulin secretion GO:0030073 39 0.055
positive regulation of cell migration GO:0030335 172 0.054
positive regulation of kinase activity GO:0033674 204 0.054
positive regulation of hormone secretion GO:0046887 25 0.054
regulation of apoptotic signaling pathway GO:2001233 175 0.054
regulation of leukocyte chemotaxis GO:0002688 46 0.053
small gtpase mediated signal transduction GO:0007264 78 0.053
positive regulation of secretion by cell GO:1903532 108 0.052
chemical homeostasis GO:0048878 306 0.052
negative regulation of natural killer cell chemotaxis GO:2000502 1 0.049
cytokine mediated signaling pathway GO:0019221 109 0.049
negative regulation of apoptotic process GO:0043066 316 0.049
positive regulation of cellular component movement GO:0051272 181 0.048
positive regulation of transferase activity GO:0051347 227 0.048
positive regulation of cell death GO:0010942 263 0.047
regulation of cellular component movement GO:0051270 334 0.047
antigen processing and presentation of polysaccharide antigen via mhc class ii GO:0002505 2 0.047
cation homeostasis GO:0055080 189 0.046
regulation of inflammatory response to antigenic stimulus GO:0002861 2 0.045
rho protein signal transduction GO:0007266 26 0.045
positive regulation of behavior GO:0048520 60 0.045
granzyme b production GO:0071613 1 0.045
positive regulation of phosphorylation GO:0042327 394 0.044
positive regulation of insulin secretion GO:0032024 10 0.044
vesicle mediated transport GO:0016192 371 0.044
cellular response to molecule of bacterial origin GO:0071219 62 0.044
mature natural killer cell chemotaxis GO:0035782 1 0.043
de novo protein folding GO:0006458 2 0.043
glucose homeostasis GO:0042593 31 0.043
g protein coupled receptor signaling pathway GO:0007186 207 0.042
response to nitrogen compound GO:1901698 184 0.042
eosinophil activation GO:0043307 3 0.040
positive regulation of cell motility GO:2000147 177 0.040
negative regulation of leukocyte proliferation GO:0070664 16 0.040
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.040
positive regulation of adaptive immune response GO:0002821 21 0.040
purine ribonucleotide catabolic process GO:0009154 404 0.040
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.039
metal ion transport GO:0030001 272 0.039
ribonucleoside catabolic process GO:0042454 406 0.039
response to organic cyclic compound GO:0014070 204 0.039
negative regulation of programmed cell death GO:0043069 321 0.039
b cell homeostasis GO:0001782 1 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.038
sensory perception of pain GO:0019233 4 0.038
detection of bacterium GO:0016045 13 0.038
organophosphate catabolic process GO:0046434 430 0.037
regulation of anatomical structure size GO:0090066 101 0.037
purine containing compound catabolic process GO:0072523 411 0.037
positive regulation of t cell activation GO:0050870 54 0.037
cell chemotaxis GO:0060326 112 0.037
cellular cation homeostasis GO:0030003 163 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.036
positive regulation of mapk cascade GO:0043410 190 0.036
peptidyl tyrosine phosphorylation GO:0018108 170 0.036
eosinophil degranulation GO:0043308 2 0.036
negative regulation of interferon gamma production GO:0032689 9 0.035
protein carbohydrate complex subunit organization GO:0071823 2 0.035
positive regulation of protein phosphorylation GO:0001934 313 0.035
purine ribonucleoside catabolic process GO:0046130 398 0.035
regulation of kinase activity GO:0043549 314 0.035
nucleoside catabolic process GO:0009164 408 0.034
regulation of interleukin 10 production GO:0032653 16 0.034
positive regulation of developmental process GO:0051094 314 0.034
positive regulation of cell adhesion GO:0045785 84 0.034
negative regulation of cell differentiation GO:0045596 171 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
fatty acid derivative metabolic process GO:1901568 35 0.034
actin filament based process GO:0030029 224 0.033
response to hexose GO:0009746 20 0.033
positive regulation of ion transport GO:0043270 87 0.032
response to lipid GO:0033993 206 0.032
regulation of proteolysis GO:0030162 293 0.032
gtp catabolic process GO:0006184 237 0.032
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.032
positive regulation of lymphocyte differentiation GO:0045621 13 0.032
regulation of immune effector process GO:0002697 91 0.032
metal ion homeostasis GO:0055065 169 0.031
positive regulation of cell differentiation GO:0045597 211 0.031
establishment of lymphocyte polarity GO:0001767 2 0.031
response to inorganic substance GO:0010035 127 0.031
positive regulation of peptide hormone secretion GO:0090277 15 0.031
response to growth factor GO:0070848 205 0.031
apoptotic signaling pathway GO:0097190 268 0.031
purine ribonucleoside metabolic process GO:0046128 437 0.031
regulation of nucleotide catabolic process GO:0030811 205 0.031
transmembrane transport GO:0055085 399 0.031
negative regulation of cellular component organization GO:0051129 235 0.030
guanosine containing compound metabolic process GO:1901068 244 0.030
negative regulation of lymphocyte activation GO:0051250 24 0.030
positive regulation of cellular component organization GO:0051130 376 0.030
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.030
positive regulation of hydrolase activity GO:0051345 331 0.030
response to hormone GO:0009725 175 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
endocytosis GO:0006897 159 0.029
regulation of nucleoside metabolic process GO:0009118 209 0.029
regulation of cellular component biogenesis GO:0044087 281 0.029
guanosine containing compound catabolic process GO:1901069 239 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.029
peptidyl tyrosine modification GO:0018212 170 0.028
positive regulation of apoptotic process GO:0043065 246 0.028
multicellular organismal aging GO:0010259 3 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.028
response to monosaccharide GO:0034284 20 0.028
negative regulation of hydrolase activity GO:0051346 182 0.028
ribonucleoside triphosphate metabolic process GO:0009199 412 0.027
ion homeostasis GO:0050801 230 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
regulation of protein kinase activity GO:0045859 289 0.027
cellular response to organic cyclic compound GO:0071407 127 0.027
signal transduction by phosphorylation GO:0023014 297 0.027
nucleoside phosphate catabolic process GO:1901292 412 0.027
nucleotide catabolic process GO:0009166 408 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
ion transmembrane transport GO:0034220 338 0.026
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.026
nucleoside triphosphate catabolic process GO:0009143 394 0.026
purine nucleotide catabolic process GO:0006195 405 0.026
detection of other organism GO:0098543 13 0.026
positive regulation of protein transport GO:0051222 135 0.026
negative regulation of catalytic activity GO:0043086 335 0.025
regulation of transferase activity GO:0051338 355 0.025
regulation of gtpase activity GO:0043087 180 0.025
nervous system development GO:0007399 293 0.025
regulation of cell adhesion GO:0030155 166 0.025
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.025
cellular response to biotic stimulus GO:0071216 71 0.024
regulation of leukocyte migration GO:0002685 63 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
chemotaxis GO:0006935 157 0.024
erk1 and erk2 cascade GO:0070371 104 0.024
cell type specific apoptotic process GO:0097285 125 0.024
production of molecular mediator of immune response GO:0002440 37 0.024
regulation of cytoskeleton organization GO:0051493 177 0.024
positive regulation of acute inflammatory response GO:0002675 2 0.024
granzyme a production GO:0035746 1 0.024
regulation of peptide secretion GO:0002791 42 0.024
regulation of chemokine mediated signaling pathway GO:0070099 6 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
interspecies interaction between organisms GO:0044419 156 0.024
eosinophil chemotaxis GO:0048245 8 0.024
gtp metabolic process GO:0046039 239 0.024
cellular ion homeostasis GO:0006873 168 0.023
cellular glucose homeostasis GO:0001678 11 0.023
cell cell signaling GO:0007267 155 0.023
regulation of macrophage cytokine production GO:0010935 4 0.023
oogenesis GO:0048477 2 0.023
positive regulation of nucleotide catabolic process GO:0030813 185 0.023
viral life cycle GO:0019058 132 0.023
response to abiotic stimulus GO:0009628 336 0.023
negative regulation of lymphocyte proliferation GO:0050672 15 0.023
positive regulation of nucleoside metabolic process GO:0045979 186 0.023
negative regulation of peptidase activity GO:0010466 91 0.023
monocarboxylic acid metabolic process GO:0032787 185 0.023
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.023
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.023
regulation of mapk cascade GO:0043408 262 0.023
regulation of system process GO:0044057 101 0.023
glycosyl compound catabolic process GO:1901658 413 0.023
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.023
cell projection organization GO:0030030 252 0.022
immunoglobulin mediated immune response GO:0016064 10 0.022
activation of phospholipase d activity GO:0031584 3 0.022
regulation of cellular response to stress GO:0080135 244 0.022
response to fungus GO:0009620 4 0.022
mhc protein complex assembly GO:0002396 4 0.022
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
cytoplasmic transport GO:0016482 379 0.022
determination of adult lifespan GO:0008340 2 0.022
ribonucleotide catabolic process GO:0009261 405 0.022
regulation of purine nucleotide catabolic process GO:0033121 205 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
positive regulation of leukocyte migration GO:0002687 46 0.022
cellular response to glucose stimulus GO:0071333 10 0.022
positive regulation of t cell differentiation GO:0045582 11 0.022
regulation of lymphocyte migration GO:2000401 22 0.022
t cell selection GO:0045058 4 0.022
female gamete generation GO:0007292 2 0.022
regulation of gtp catabolic process GO:0033124 180 0.021
negative regulation of cell motility GO:2000146 104 0.021
regulation of interleukin 4 production GO:0032673 7 0.021
regulation of ras protein signal transduction GO:0046578 155 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
purine nucleoside triphosphate catabolic process GO:0009146 392 0.021
eosinophil mediated immunity GO:0002447 2 0.021
positive regulation of catabolic process GO:0009896 310 0.021
positive regulation of peptide secretion GO:0002793 15 0.021
leukocyte activation involved in immune response GO:0002366 30 0.021
negative regulation of t helper 1 cell activation GO:2000518 1 0.021
regulation of ras gtpase activity GO:0032318 128 0.021
positive regulation of t cell apoptotic process GO:0070234 4 0.021
positive regulation of locomotion GO:0040017 186 0.021
reactive oxygen species metabolic process GO:0072593 75 0.021
positive regulation of organelle organization GO:0010638 195 0.021
leukocyte chemotaxis GO:0030595 76 0.021
stress activated protein kinase signaling cascade GO:0031098 94 0.021
second messenger mediated signaling GO:0019932 78 0.020
response to virus GO:0009615 126 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
positive regulation of nucleotide metabolic process GO:0045981 230 0.020
divalent metal ion transport GO:0070838 152 0.020
cellular response to dna damage stimulus GO:0006974 379 0.020
cellular response to monosaccharide stimulus GO:0071326 10 0.020
intracellular protein transport GO:0006886 270 0.020
mitotic cell cycle GO:0000278 326 0.020
viral process GO:0016032 146 0.020
regulation of cell differentiation GO:0045595 393 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.020
multi organism cellular process GO:0044764 156 0.020
growth GO:0040007 202 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
response to molecule of bacterial origin GO:0002237 82 0.019
monocarboxylic acid biosynthetic process GO:0072330 67 0.019
sequestering of metal ion GO:0051238 24 0.019
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.019
calcium ion homeostasis GO:0055074 122 0.019
cell morphogenesis GO:0000902 296 0.019
protein catabolic process GO:0030163 325 0.019
sequestering of calcium ion GO:0051208 17 0.019
negative regulation of homeostatic process GO:0032845 59 0.019
regulation of viral process GO:0050792 103 0.019
single organism cell adhesion GO:0098602 179 0.019
positive regulation of gtp catabolic process GO:0033126 166 0.019
regulation of neutrophil migration GO:1902622 10 0.018
positive regulation of protein secretion GO:0050714 60 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
generation of neurons GO:0048699 152 0.018
response to carbohydrate GO:0009743 21 0.018
behavior GO:0007610 112 0.018
response to tumor necrosis factor GO:0034612 76 0.018
inositol lipid mediated signaling GO:0048017 55 0.018
glycerolipid metabolic process GO:0046486 107 0.018
regulation of peptidase activity GO:0052547 180 0.018
response to glucose GO:0009749 19 0.018
negative regulation of developmental process GO:0051093 247 0.018
cellular response to nitrogen compound GO:1901699 144 0.018
regulation of ion transport GO:0043269 189 0.018
cellular divalent inorganic cation homeostasis GO:0072503 128 0.018
positive regulation of leukocyte chemotaxis GO:0002690 38 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.018
regulation of protein binding GO:0043393 66 0.018
negative regulation of intracellular signal transduction GO:1902532 183 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.017
neuromuscular junction development GO:0007528 3 0.017
negative regulation of inflammatory response GO:0050728 22 0.017
regulation of lipid metabolic process GO:0019216 96 0.017
protein processing GO:0016485 226 0.017
negative regulation of lymphocyte migration GO:2000402 4 0.017
regulation of c c chemokine binding GO:2001263 1 0.017
granulocyte chemotaxis GO:0071621 37 0.017
negative regulation of protein metabolic process GO:0051248 391 0.017
single organismal cell cell adhesion GO:0016337 148 0.017
response to oxidative stress GO:0006979 121 0.017
regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002586 3 0.017
regulation of ion transmembrane transport GO:0034765 132 0.017
reactive nitrogen species metabolic process GO:2001057 3 0.017
maintenance of location GO:0051235 112 0.017
cellular response to organonitrogen compound GO:0071417 124 0.017
negative regulation of cellular component movement GO:0051271 106 0.017
memory GO:0007613 3 0.017
interleukin 1 beta production GO:0032611 22 0.017
phospholipid metabolic process GO:0006644 99 0.017
carbohydrate homeostasis GO:0033500 31 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.016
regulation of intracellular transport GO:0032386 195 0.016
response to nitric oxide GO:0071731 4 0.016
regulation of cell cycle GO:0051726 393 0.016
regulation of epithelial cell proliferation GO:0050678 113 0.016
negative regulation of t cell apoptotic process GO:0070233 4 0.016
positive regulation of stress activated mapk cascade GO:0032874 60 0.016
negative regulation of leukocyte differentiation GO:1902106 24 0.016
response to organonitrogen compound GO:0010243 156 0.016
interleukin 4 production GO:0032633 7 0.016
regulation of rho protein signal transduction GO:0035023 79 0.016
regulation of sensory perception GO:0051931 3 0.016
protein carbohydrate complex assembly GO:0065006 2 0.016
negative regulation of apoptotic signaling pathway GO:2001234 97 0.016
divalent inorganic cation homeostasis GO:0072507 136 0.016
dephosphorylation GO:0016311 209 0.016
reactive oxygen species biosynthetic process GO:1903409 4 0.016
humoral immune response mediated by circulating immunoglobulin GO:0002455 5 0.016
mitotic cell cycle process GO:1903047 286 0.016
single organism cellular localization GO:1902580 332 0.016
ossification GO:0001503 121 0.016
actin filament organization GO:0007015 128 0.015
cellular calcium ion homeostasis GO:0006874 117 0.015
regulation of protein processing GO:0070613 150 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
positive regulation of cd8 positive alpha beta t cell activation GO:2001187 1 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.015
regulation of protein maturation GO:1903317 150 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.015
regulation of actin filament based process GO:0032970 141 0.015
negative regulation of cell migration GO:0030336 102 0.015
nuclear transport GO:0051169 179 0.015
negative regulation of chemotaxis GO:0050922 13 0.015
regulation of transmembrane transport GO:0034762 139 0.015
regulation of lymphocyte differentiation GO:0045619 22 0.015
regulation of metal ion transport GO:0010959 120 0.015
negative regulation of alpha beta t cell activation GO:0046636 3 0.015
positive regulation of granzyme b production GO:0071663 1 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
cellular response to lipid GO:0071396 127 0.015
actin cytoskeleton organization GO:0030036 207 0.015
cellular component morphogenesis GO:0032989 314 0.015
protein kinase b signaling GO:0043491 69 0.015
regulation of protein complex assembly GO:0043254 147 0.015
blood vessel morphogenesis GO:0048514 162 0.015
regulation of adaptive immune response GO:0002819 33 0.015
membrane organization GO:0061024 292 0.015
positive regulation of cytokine secretion GO:0050715 42 0.015

HLA-DRB4 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.587
musculoskeletal system disease DOID:17 223 0.418
connective tissue disease DOID:65 109 0.148
bone disease DOID:0080001 88 0.148
hypersensitivity reaction disease DOID:0060056 25 0.137
central nervous system disease DOID:331 186 0.093
nervous system disease DOID:863 431 0.093
neurodegenerative disease DOID:1289 102 0.087
disease of metabolism DOID:0014667 295 0.024
sensory system disease DOID:0050155 203 0.020
inherited metabolic disorder DOID:655 242 0.017