Homo sapiens

111 known processes

HLA-G

major histocompatibility complex, class I, G

(Aliases: MHC-G)

HLA-G biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception GO:0050907 33 1.000
Human
antigen processing and presentation via mhc class ib GO:0002475 3 1.000
Human
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 1.000
regulation of regulatory t cell differentiation GO:0045589 4 1.000
positive regulation of regulatory t cell differentiation GO:0045591 3 1.000
dendritic cell differentiation GO:0097028 13 1.000
regulation of dendritic cell differentiation GO:2001198 3 1.000
positive regulation of natural killer cell mediated immunity GO:0002717 12 1.000
Human
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 1.000
Human
negative regulation of dendritic cell differentiation GO:2001199 2 1.000
positive regulation of t cell tolerance induction GO:0002666 2 1.000
detection of external biotic stimulus GO:0098581 19 1.000
Human
sensory perception of taste GO:0050909 36 1.000
Human
regulation of natural killer cell mediated immunity GO:0002715 16 0.999
Human
negative regulation of leukocyte mediated immunity GO:0002704 14 0.999
Human
detection of chemical stimulus GO:0009593 55 0.999
Human
sensory perception of chemical stimulus GO:0007606 38 0.999
Human
antigen processing and presentation of endogenous antigen GO:0019883 7 0.998
Human
immune response inhibiting signal transduction GO:0002765 4 0.998
t cell tolerance induction GO:0002517 4 0.997
negative regulation of t cell proliferation GO:0042130 8 0.997
sensory perception of bitter taste GO:0050913 28 0.997
Human
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 5 0.996
Human
regulation of t cell mediated cytotoxicity GO:0001914 8 0.995
Human
positive regulation of lymphocyte differentiation GO:0045621 13 0.995
negative regulation of leukocyte mediated cytotoxicity GO:0001911 5 0.994
Human
natural killer cell mediated immunity GO:0002228 23 0.991
Human
detection of chemical stimulus involved in sensory perception of taste GO:0050912 31 0.989
Human
antigen processing and presentation of peptide antigen via mhc class i GO:0002474 6 0.987
Human
regulation of t cell mediated immunity GO:0002709 18 0.976
Human
detection of biotic stimulus GO:0009595 21 0.975
Human
positive regulation of tolerance induction GO:0002645 2 0.974
antigen processing and presentation of endogenous peptide antigen via mhc class ib GO:0002476 2 0.973
Human
negative regulation of cell killing GO:0031342 5 0.972
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway GO:0002484 3 0.968
Human
antigen processing and presentation GO:0019882 33 0.966
Human
cation transport GO:0006812 331 0.965
Human
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.965
Human
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.963
Human
regulation of leukocyte mediated immunity GO:0002703 38 0.959
Human
tolerance induction GO:0002507 6 0.959
import into cell GO:0098657 2 0.957
Human
retina homeostasis GO:0001895 42 0.957
Human
natural killer cell mediated cytotoxicity GO:0042267 23 0.954
Human
multicellular organismal homeostasis GO:0048871 67 0.951
Human
lymphocyte mediated immunity GO:0002449 48 0.949
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independent GO:0002486 3 0.947
Human
regulation of cell killing GO:0031341 22 0.936
Human
regulation of leukocyte proliferation GO:0070663 67 0.935
detection of stimulus GO:0051606 85 0.930
Human
cell killing GO:0001906 34 0.929
Human
antigen processing and presentation of peptide antigen GO:0048002 18 0.925
Human
regulation of leukocyte mediated cytotoxicity GO:0001910 19 0.916
Human
t cell mediated cytotoxicity GO:0001913 9 0.909
Human
regulation of lymphocyte mediated immunity GO:0002706 33 0.907
Human
regulation of memory t cell activation GO:2000567 1 0.902
Human
iron ion import into cell GO:0097459 2 0.898
Human
detection of other organism GO:0098543 13 0.879
Human
detection of bacterium GO:0016045 13 0.879
Human
metal ion transport GO:0030001 272 0.875
Human
positive regulation of memory t cell activation GO:2000568 1 0.872
Human
positive regulation of t cell activation GO:0050870 54 0.864
interleukin 12 production GO:0032615 15 0.861
positive regulation of interferon gamma production GO:0032729 26 0.858
Human
regulation of interleukin 10 secretion GO:2001179 4 0.851
regulation of mononuclear cell proliferation GO:0032944 65 0.849
positive regulation of leukocyte activation GO:0002696 80 0.847
regulation of adaptive immune response GO:0002819 33 0.844
Human
positive regulation of interleukin 12 production GO:0032735 8 0.841
inorganic cation import into cell GO:0098659 2 0.826
Human
regulation of leukocyte differentiation GO:1902105 61 0.822
cell adhesion GO:0007155 325 0.819
Human
detection of stimulus involved in sensory perception GO:0050906 43 0.817
Human
memory t cell activation GO:0035709 1 0.809
Human
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.805
negative regulation of cell proliferation GO:0008285 228 0.804
regulation of t cell activation GO:0050863 77 0.800
negative regulation of innate immune response GO:0045824 18 0.796
Human
negative regulation of leukocyte activation GO:0002695 26 0.793
positive regulation of defense response GO:0031349 87 0.793
Human
negative regulation of immune response GO:0050777 40 0.789
Human
lymphocyte proliferation GO:0046651 70 0.784
regulation of lymphocyte proliferation GO:0050670 64 0.779
interferon gamma production GO:0032609 39 0.777
Human
negative regulation of immune effector process GO:0002698 38 0.776
Human
positive regulation of t cell differentiation GO:0045582 11 0.776
regulation of cytokine production GO:0001817 232 0.764
regulatory t cell differentiation GO:0045066 5 0.758
positive regulation of cell activation GO:0050867 81 0.749
transition metal ion transport GO:0000041 23 0.746
Human
immune effector process GO:0002252 159 0.736
Human
tissue homeostasis GO:0001894 63 0.733
Human
mononuclear cell proliferation GO:0032943 71 0.718
positive regulation of developmental process GO:0051094 314 0.716
response to biotic stimulus GO:0009607 276 0.706
Human
regulation of t cell proliferation GO:0042129 42 0.702
positive regulation of leukocyte differentiation GO:1902107 37 0.694
positive regulation of adaptive immune response GO:0002821 21 0.689
Human
lymphocyte differentiation GO:0030098 35 0.687
positive regulation of leukocyte mediated immunity GO:0002705 24 0.686
Human
positive regulation of t cell mediated immunity GO:0002711 12 0.684
Human
hemopoiesis GO:0030097 180 0.683
positive regulation of cytokine production GO:0001819 167 0.668
immune response regulating signaling pathway GO:0002764 97 0.665
regulation of lymphocyte differentiation GO:0045619 22 0.658
positive regulation of immune effector process GO:0002699 40 0.635
Human
cytokine production GO:0001816 247 0.625
positive regulation of immune response GO:0050778 159 0.622
Human
t cell proliferation GO:0042098 45 0.620
regulation of tolerance induction GO:0002643 4 0.617
protection from natural killer cell mediated cytotoxicity GO:0042270 3 0.606
Human
positive regulation of cell differentiation GO:0045597 211 0.594
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.594
leukocyte proliferation GO:0070661 74 0.593
positive regulation of t cell mediated cytotoxicity GO:0001916 7 0.590
Human
immune response GO:0006955 307 0.585
negative regulation of multicellular organismal process GO:0051241 317 0.576
regulation of immune response GO:0050776 201 0.570
regulation of cell activation GO:0050865 125 0.562
response to bacterium GO:0009617 144 0.558
Human
t cell mediated immunity GO:0002456 25 0.555
Human
negative regulation of leukocyte differentiation GO:1902106 24 0.549
leukocyte mediated immunity GO:0002443 59 0.548
Human
regulation of interleukin 12 production GO:0032655 15 0.543
negative regulation of lymphocyte mediated immunity GO:0002707 12 0.531
Human
innate immune response GO:0045087 178 0.526
Human
inorganic ion import into cell GO:0099587 2 0.522
Human
regulation of interferon gamma production GO:0032649 36 0.519
Human
regulation of t cell tolerance induction GO:0002664 4 0.518
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.517
Human
regulation of t cell differentiation GO:0045580 19 0.512
leukocyte mediated cytotoxicity GO:0001909 27 0.498
Human
response to external biotic stimulus GO:0043207 261 0.495
Human
immune system development GO:0002520 195 0.480
positive regulation of cell killing GO:0031343 19 0.477
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.476
Human
negative regulation of developmental process GO:0051093 247 0.462
adaptive immune response GO:0002250 49 0.456
Human
negative regulation of leukocyte proliferation GO:0070664 16 0.439
anatomical structure homeostasis GO:0060249 100 0.431
Human
positive regulation of immune system process GO:0002684 283 0.428
regulation of leukocyte activation GO:0002694 115 0.404
system process GO:0003008 349 0.403
Human
regulation of cytokine secretion GO:0050707 57 0.383
lymphocyte activation GO:0046649 133 0.379
regulation of lymphocyte activation GO:0051249 103 0.375
regulation of defense response GO:0031347 154 0.368
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.365
response to other organism GO:0051707 261 0.356
Human
negative regulation of immune system process GO:0002683 136 0.339
negative regulation of secretion GO:0051048 58 0.334
negative regulation of cell activation GO:0050866 33 0.319
negative regulation of cell differentiation GO:0045596 171 0.318
sensory perception GO:0007600 103 0.317
Human
positive regulation of leukocyte mediated cytotoxicity GO:0001912 16 0.316
Human
regulation of cell differentiation GO:0045595 393 0.312
negative regulation of cd8 positive alpha beta t cell activation GO:2001186 1 0.312
t cell activation GO:0042110 99 0.309
t cell differentiation GO:0030217 29 0.305
cell activation GO:0001775 213 0.300
negative regulation of defense response GO:0031348 47 0.280
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i GO:0019885 5 0.277
Human
defense response GO:0006952 315 0.268
Human
regulation of innate immune response GO:0045088 97 0.265
Human
leukocyte differentiation GO:0002521 98 0.256
negative regulation of t cell activation GO:0050868 18 0.249
negative regulation of lymphocyte activation GO:0051250 24 0.244
antigen processing and presentation of peptide antigen via mhc class ib GO:0002428 2 0.239
Human
type i interferon signaling pathway GO:0060337 11 0.234
regulation of protein secretion GO:0050708 86 0.205
biological adhesion GO:0022610 331 0.205
Human
antigen processing and presentation of endogenous peptide antigen GO:0002483 6 0.202
Human
leukocyte activation GO:0045321 164 0.198
type i interferon secretion GO:0072641 1 0.185
regulation of immune effector process GO:0002697 91 0.180
Human
regulation of gamma delta t cell activation involved in immune response GO:2001191 1 0.164
purine ribonucleoside metabolic process GO:0046128 437 0.163
regulation of interferon gamma biosynthetic process GO:0045072 8 0.107
negative regulation of lymphocyte proliferation GO:0050672 15 0.107
cd8 positive alpha beta t cell activation GO:0036037 3 0.103
secretion by cell GO:0032940 226 0.102
interleukin 6 production GO:0032635 37 0.098
cell projection organization GO:0030030 252 0.097
negative regulation of interferon beta production GO:0032688 4 0.089
neurological system process GO:0050877 163 0.087
Human
secretion GO:0046903 254 0.085
regulation of secretion GO:0051046 194 0.081
divalent inorganic cation transport GO:0072511 158 0.080
post embryonic development GO:0009791 2 0.080
negative regulation of mononuclear cell proliferation GO:0032945 15 0.080
iron ion transport GO:0006826 12 0.076
Human
cytoplasmic transport GO:0016482 379 0.072
intracellular protein transport GO:0006886 270 0.066
positive regulation of innate immune response GO:0045089 79 0.062
Human
regulation of establishment of protein localization GO:0070201 242 0.062
cytokine metabolic process GO:0042107 38 0.060
regulation of protein transport GO:0051223 213 0.059
regulation of cellular ketone metabolic process GO:0010565 50 0.058
negative regulation of interferon gamma biosynthetic process GO:0045077 1 0.055
regulation of cell cycle GO:0051726 393 0.053
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.052
response to interferon gamma GO:0034341 39 0.051
regulation of protein localization GO:0032880 296 0.051
positive regulation of antigen processing and presentation GO:0002579 1 0.050
mapk cascade GO:0000165 288 0.050
negative regulation of cellular protein metabolic process GO:0032269 353 0.048
positive regulation of lymphocyte proliferation GO:0050671 46 0.045
cellular response to oxidative stress GO:0034599 85 0.045
regulation of cellular amino acid metabolic process GO:0006521 6 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.044
purine nucleoside triphosphate metabolic process GO:0009144 412 0.043
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.041
Human
negative regulation of cell death GO:0060548 345 0.041
positive regulation of secretion GO:0051047 116 0.040
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.040
positive regulation of cell proliferation GO:0008284 301 0.037
cytokine production involved in immune response GO:0002367 27 0.036
negative regulation of transforming growth factor beta secretion GO:2001202 1 0.036
iron ion import GO:0097286 5 0.036
Human
purine nucleotide catabolic process GO:0006195 405 0.034
cell development GO:0048468 328 0.033
regulation of viral genome replication GO:0045069 48 0.032
divalent metal ion transport GO:0070838 152 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
regulation of interferon beta production GO:0032648 22 0.030
regulation of dendritic cell apoptotic process GO:2000668 4 0.029
negative regulation of serotonin secretion GO:0014063 1 0.029
multicellular organismal aging GO:0010259 3 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
nucleoside catabolic process GO:0009164 408 0.027
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
single organism cell adhesion GO:0098602 179 0.026
regulation of secretion by cell GO:1903530 177 0.026
t cell differentiation in thymus GO:0033077 4 0.026
immune response activating signal transduction GO:0002757 90 0.025
interferon beta secretion GO:0035546 1 0.025
regulation of erk1 and erk2 cascade GO:0070372 99 0.024
response to virus GO:0009615 126 0.024
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.024
negative regulation of dendritic cell apoptotic process GO:2000669 3 0.023
negative regulation of protein metabolic process GO:0051248 391 0.022
positive regulation of lymphocyte activation GO:0051251 73 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
amine metabolic process GO:0009308 44 0.022
positive regulation of t cell proliferation GO:0042102 33 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.022
determination of adult lifespan GO:0008340 2 0.022
regulation of calcium ion transport GO:0051924 79 0.021
nitrogen compound transport GO:0071705 191 0.021
regulation of ion transport GO:0043269 189 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
oogenesis GO:0048477 2 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
nucleoside phosphate biosynthetic process GO:1901293 109 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
negative regulation of alpha beta t cell activation GO:0046636 3 0.019
cellular response to oxygen containing compound GO:1901701 276 0.019
cellular amine metabolic process GO:0044106 41 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
purine containing compound catabolic process GO:0072523 411 0.018
single organismal cell cell adhesion GO:0016337 148 0.018
microtubule cytoskeleton organization GO:0000226 176 0.018
serotonin transport GO:0006837 3 0.018
negative regulation of antigen processing and presentation GO:0002578 5 0.018
positive regulation of leukocyte proliferation GO:0070665 48 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
organic hydroxy compound transport GO:0015850 63 0.017
negative regulation of protein transport GO:0051224 75 0.017
cytokine secretion GO:0050663 64 0.017
regulation of multi organism process GO:0043900 157 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
regulation of cell development GO:0060284 161 0.016
cellular protein complex assembly GO:0043623 188 0.016
fc receptor mediated inhibitory signaling pathway GO:0002774 2 0.016
cellular ketone metabolic process GO:0042180 80 0.016
regulation of gamma delta t cell activation GO:0046643 1 0.016
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.016
positive regulation of cell death GO:0010942 263 0.016
protein localization to organelle GO:0033365 280 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
single organism reproductive process GO:0044702 98 0.015
neuron projection development GO:0031175 106 0.015
ossification GO:0001503 121 0.015
signal transduction by phosphorylation GO:0023014 297 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
oocyte development GO:0048599 1 0.015
serotonin secretion GO:0001820 1 0.015
regulation of homeostatic process GO:0032844 121 0.015
calcium ion transport GO:0006816 147 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
blastoderm segmentation GO:0007350 2 0.015
response to oxygen containing compound GO:1901700 369 0.014
interaction with host GO:0051701 42 0.014
cellular macromolecular complex assembly GO:0034622 324 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
regulation of serotonin secretion GO:0014062 1 0.014
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.014
regulation of defense response to virus GO:0050688 33 0.014
cellular protein catabolic process GO:0044257 261 0.014
interleukin 10 production GO:0032613 17 0.014
divalent inorganic cation homeostasis GO:0072507 136 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
t cell proliferation involved in immune response GO:0002309 1 0.014
positive regulation of interleukin 10 secretion GO:2001181 2 0.013
protein secretion GO:0009306 98 0.013
cell projection assembly GO:0030031 126 0.013
cell type specific apoptotic process GO:0097285 125 0.013
regulation of response to external stimulus GO:0032101 222 0.013
negative regulation of programmed cell death GO:0043069 321 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
nucleotide catabolic process GO:0009166 408 0.013
single organism carbohydrate metabolic process GO:0044723 193 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
mitotic cell cycle process GO:1903047 286 0.013
negative regulation of cellular component organization GO:0051129 235 0.013
interleukin 12 secretion GO:0072610 1 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
regulation of actin filament based process GO:0032970 141 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
modification dependent protein catabolic process GO:0019941 209 0.012
osteoblast differentiation GO:0001649 92 0.012
positive regulation of mast cell chemotaxis GO:0060754 4 0.012
neurogenesis GO:0022008 169 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.012
regulation of cellular response to stress GO:0080135 244 0.012
viral process GO:0016032 146 0.012
growth GO:0040007 202 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.012
lipid metabolic process GO:0006629 381 0.012
microtubule based process GO:0007017 210 0.011
positive regulation of mononuclear cell proliferation GO:0032946 47 0.011
regulation of alpha beta t cell activation GO:0046634 13 0.011
transforming growth factor beta secretion GO:0038044 1 0.011
response to type i interferon GO:0034340 14 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
organophosphate catabolic process GO:0046434 430 0.011
regulation of tumor necrosis factor production GO:0032680 43 0.011
interleukin 10 secretion GO:0072608 5 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
positive regulation of cytolysis GO:0045919 3 0.011
salivary gland morphogenesis GO:0007435 4 0.011
defense response to virus GO:0051607 71 0.011
negative regulation of protein modification process GO:0031400 200 0.011
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001188 2 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.010
regulation of interleukin 12 secretion GO:2001182 1 0.010
nucleoside phosphate catabolic process GO:1901292 412 0.010
chemical homeostasis GO:0048878 306 0.010
negative regulation of cell cycle GO:0045786 193 0.010
sensory perception of pain GO:0019233 4 0.010
regulation of transforming growth factor beta secretion GO:2001201 1 0.010
modification dependent macromolecule catabolic process GO:0043632 212 0.010

HLA-G disease predictions

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 13 0.996
Human
disease by infectious agent DOID:0050117 34 0.996
Human
viral infectious disease DOID:934 13 0.996
Human
human immunodeficiency virus infectious disease DOID:526 13 0.996
Human
musculoskeletal system disease DOID:17 223 0.457
disease of metabolism DOID:0014667 295 0.093
Human
lipid storage disease DOID:9455 28 0.093
lysosomal storage disease DOID:3211 47 0.093
inherited metabolic disorder DOID:655 242 0.093
Human
neuronal ceroid lipofuscinosis DOID:14503 11 0.093
primary immunodeficiency disease DOID:612 36 0.079
severe combined immunodeficiency DOID:627 10 0.079
combined t cell and b cell immunodeficiency DOID:628 12 0.079
immune system disease DOID:2914 155 0.079
integumentary system disease DOID:16 43 0.054
Human
bone disease DOID:0080001 88 0.019
connective tissue disease DOID:65 109 0.019
skin disease DOID:37 33 0.012
Human
disease of cellular proliferation DOID:14566 174 0.010