IMP
Process View
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independent
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independent"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| HLA-A | major histocompatibility complex, class I, A | 0.996 | ||
| HLA-C | major histocompatibility complex, class I, C | 0.992 | ||
| HLA-B | major histocompatibility complex, class I, B | 0.991 | ||
| B2M | beta-2-microglobulin | 0.986 | ||
| HLA-E | major histocompatibility complex, class I, E | 0.952 | Human | |
| HLA-G | major histocompatibility complex, class I, G | 0.947 | Human | |
| HLA-F | major histocompatibility complex, class I, F | 0.560 | Human | |
| TAPBP | TAP binding protein (tapasin) | 0.120 | ||
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.056 | ||
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.031 | ||
| IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.017 | ||
| IFITM1 | interferon induced transmembrane protein 1 (9-27) | 0.012 | ||
| PSAP | prosaposin | 0.011 |