Homo sapiens

159 known processes

HTT

huntingtin

(Aliases: IT15,HD)

HTT biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
bmp signaling pathway involved in heart development GO:0061312 3 0.997
epithelium development GO:0060429 227 0.997
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.989
vesicle mediated transport GO:0016192 371 0.988
covalent chromatin modification GO:0016569 254 0.987
positive regulation of cellular catabolic process GO:0031331 284 0.982
internal protein amino acid acetylation GO:0006475 101 0.973
protein localization to membrane GO:0072657 160 0.925
anatomical structure formation involved in morphogenesis GO:0048646 284 0.923
Mouse
histone modification GO:0016570 251 0.905
histone h4 acetylation GO:0043967 47 0.893
protein modification by small protein conjugation GO:0032446 342 0.882
endomembrane system organization GO:0010256 196 0.858
positive regulation of cellular component organization GO:0051130 376 0.850
single organism carbohydrate metabolic process GO:0044723 193 0.835
histone acetylation GO:0016573 93 0.823
protein polymerization GO:0051258 71 0.781
plasma membrane organization GO:0007009 115 0.756
regulation of cell migration GO:0030334 289 0.747
regulation of protein complex assembly GO:0043254 147 0.734
positive regulation of programmed cell death GO:0043068 249 0.732
regulation of transcription involved in cell fate commitment GO:0060850 6 0.724
secretion GO:0046903 254 0.723
Mouse
positive regulation of apoptotic process GO:0043065 246 0.722
cytokinesis GO:0000910 96 0.719
chromatin modification GO:0016568 298 0.687
positive regulation of cell death GO:0010942 263 0.687
carbohydrate metabolic process GO:0005975 207 0.683
negative regulation of protein metabolic process GO:0051248 391 0.676
Rat
carbohydrate derivative biosynthetic process GO:1901137 207 0.648
chromatin organization GO:0006325 351 0.638
cellular response to dna damage stimulus GO:0006974 379 0.628
cellular amino acid metabolic process GO:0006520 116 0.623
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 127 0.622
Rat
histone serine phosphorylation GO:0035404 4 0.618
regulation of cellular component size GO:0032535 82 0.616
regulation of protein polymerization GO:0032271 63 0.578
regulation of anatomical structure size GO:0090066 101 0.576
reactive oxygen species metabolic process GO:0072593 75 0.559
membrane organization GO:0061024 292 0.550
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.546
positive regulation of nucleotide metabolic process GO:0045981 230 0.523
regulation of purine nucleotide catabolic process GO:0033121 205 0.521
negative regulation of multicellular organismal process GO:0051241 317 0.519
positive regulation of hydrolase activity GO:0051345 331 0.507
negative regulation of apoptotic process GO:0043066 316 0.505
regulation of vasculature development GO:1901342 97 0.504
generation of neurons GO:0048699 152 0.503
Mouse
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.502
regulation of carbohydrate metabolic process GO:0006109 54 0.499
regulation of methylation dependent chromatin silencing GO:0090308 3 0.499
glycoprotein biosynthetic process GO:0009101 91 0.493
regulation of growth GO:0040008 165 0.489
establishment of vesicle localization GO:0051650 23 0.484
regulation of cell motility GO:2000145 299 0.484
neuromuscular junction development GO:0007528 3 0.475
histone h3 acetylation GO:0043966 45 0.468
ultradian rhythm GO:0007624 1 0.461
hindbrain development GO:0030902 3 0.442
cardiac cell fate determination GO:0060913 3 0.440
vesicle localization GO:0051648 26 0.438
response to drug GO:0042493 81 0.436
positive regulation of developmental process GO:0051094 314 0.428
cellular response to oxidative stress GO:0034599 85 0.418
regulation of actin filament polymerization GO:0030833 50 0.410
cell fate determination GO:0001709 3 0.409
negative regulation of cell motility GO:2000146 104 0.401
cellular protein complex assembly GO:0043623 188 0.400
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 1 0.393
actin cytoskeleton organization GO:0030036 207 0.392
purine ribonucleoside catabolic process GO:0046130 398 0.369
cell proliferation involved in heart valve development GO:2000793 1 0.368
purine nucleoside triphosphate metabolic process GO:0009144 412 0.365
nucleoside monophosphate metabolic process GO:0009123 191 0.364
positive regulation of cellular component biogenesis GO:0044089 158 0.363
purine nucleoside triphosphate catabolic process GO:0009146 392 0.362
protein dna complex subunit organization GO:0071824 80 0.362
purine ribonucleotide biosynthetic process GO:0009152 79 0.362
somatic muscle development GO:0007525 1 0.361
establishment of protein localization to membrane GO:0090150 121 0.358
synaptic vesicle endocytosis GO:0048488 2 0.347
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.334
cellular macromolecular complex assembly GO:0034622 324 0.333
protein catabolic process GO:0030163 325 0.332
protein localization to plasma membrane GO:0072659 93 0.325
regulation of histone modification GO:0031056 47 0.320
synaptic vesicle transport GO:0048489 5 0.318
negative regulation of cellular component movement GO:0051271 106 0.306
negative regulation of hyaluronan biosynthetic process GO:1900126 3 0.306
negative regulation of camp mediated signaling GO:0043951 4 0.301
regulation of proteolysis GO:0030162 293 0.298
Rat
regulation of interferon beta biosynthetic process GO:0045357 4 0.296
vesicle organization GO:0016050 62 0.294
positive regulation of growth GO:0045927 58 0.272
cell development GO:0048468 328 0.270
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.267
regulation of neuronal synaptic plasticity GO:0048168 1 0.259
regulation of secretion GO:0051046 194 0.257
protein acylation GO:0043543 138 0.254
negative regulation of cell death GO:0060548 345 0.252
negative regulation of ruffle assembly GO:1900028 3 0.251
positive regulation of transport GO:0051050 336 0.251
positive regulation of organelle organization GO:0010638 195 0.248
organophosphate biosynthetic process GO:0090407 163 0.247
regulation of epithelial cell migration GO:0010632 93 0.241
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.238
regulation of stress fiber assembly GO:0051492 32 0.238
nucleotide catabolic process GO:0009166 408 0.233
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.233
hematopoietic or lymphoid organ development GO:0048534 186 0.233
nervous system development GO:0007399 293 0.232
Mouse Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.231
cell projection assembly GO:0030031 126 0.229
regulation of mitotic cell cycle phase transition GO:1901990 118 0.228
establishment of organelle localization GO:0051656 59 0.228
nucleoside triphosphate catabolic process GO:0009143 394 0.226
cell fate commitment GO:0045165 27 0.224
ribose phosphate biosynthetic process GO:0046390 82 0.219
positive regulation of catabolic process GO:0009896 310 0.219
synaptic vesicle localization GO:0097479 5 0.217
innate immune response GO:0045087 178 0.217
purine containing compound biosynthetic process GO:0072522 88 0.212
regulation of myeloid cell differentiation GO:0045637 81 0.212
regulation of small gtpase mediated signal transduction GO:0051056 156 0.207
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.207
organ morphogenesis GO:0009887 147 0.206
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 187 0.201
cellular response to peptide GO:1901653 59 0.198
ribonucleoside triphosphate metabolic process GO:0009199 412 0.197
ameboidal type cell migration GO:0001667 135 0.184
regulation of binding GO:0051098 111 0.183
purine ribonucleoside metabolic process GO:0046128 437 0.181
bmp signaling pathway involved in heart induction GO:0003130 3 0.179
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.178
regulation of cell cycle GO:0051726 393 0.178
cellular amine metabolic process GO:0044106 41 0.178
lens development in camera type eye GO:0002088 2 0.176
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.173
cell cell junction organization GO:0045216 69 0.170
signal release GO:0023061 70 0.169
Mouse
cellular response to external stimulus GO:0071496 111 0.166
organonitrogen compound biosynthetic process GO:1901566 200 0.163
Mouse
protein ubiquitination GO:0016567 314 0.163
developmental growth GO:0048589 48 0.159
positive regulation of cell projection organization GO:0031346 64 0.157
cellular response to abiotic stimulus GO:0071214 117 0.155
nucleoside phosphate catabolic process GO:1901292 412 0.153
actin filament polymerization GO:0030041 45 0.153
glycoprotein metabolic process GO:0009100 110 0.151
nucleoside catabolic process GO:0009164 408 0.151
regulation of chromatin modification GO:1903308 51 0.150
intracellular protein transport GO:0006886 270 0.150
Mouse
internal peptidyl lysine acetylation GO:0018393 97 0.150
regulation of mapk cascade GO:0043408 262 0.148
dna packaging GO:0006323 77 0.147
response to oxidative stress GO:0006979 121 0.145
mitotic cell cycle process GO:1903047 286 0.145
regulation of cytoskeleton organization GO:0051493 177 0.144
canonical wnt signaling pathway GO:0060070 116 0.143
negative regulation of muscle contraction GO:0045932 3 0.142
cellular ketone metabolic process GO:0042180 80 0.139
cell projection organization GO:0030030 252 0.139
stress fiber assembly GO:0043149 40 0.139
establishment of protein localization to plasma membrane GO:0090002 68 0.139
positive regulation of protein polymerization GO:0032273 45 0.135
cellular response to insulin stimulus GO:0032869 41 0.135
regulation of reactive oxygen species metabolic process GO:2000377 41 0.135
embryo development ending in birth or egg hatching GO:0009792 34 0.135
Mouse
peptidyl serine modification GO:0018209 106 0.134
negative regulation of cell migration GO:0030336 102 0.134
response to extracellular stimulus GO:0009991 85 0.134
negative regulation of cell differentiation GO:0045596 171 0.133
regulation of angiogenesis GO:0045765 92 0.132
polysaccharide metabolic process GO:0005976 33 0.131
mapk cascade GO:0000165 288 0.131
regulation of myeloid leukocyte differentiation GO:0002761 39 0.129
response to nitrogen compound GO:1901698 184 0.128
cellular response to peptide hormone stimulus GO:0071375 56 0.128
negative regulation of catalytic activity GO:0043086 335 0.128
Rat
regulation of actin filament length GO:0030832 56 0.128
determination of adult lifespan GO:0008340 2 0.123
Mouse
taxis GO:0042330 157 0.123
endodermal mesodermal cell signaling GO:0003133 3 0.121
regulation of cellular ketone metabolic process GO:0010565 50 0.119
eye development GO:0001654 42 0.119
skin development GO:0043588 76 0.116
mechanosensory behavior GO:0007638 4 0.116
regulation of keratinocyte apoptotic process GO:1902172 1 0.116
axon cargo transport GO:0008088 2 0.116
Mouse
regulation of heart induction by regulation of canonical wnt signaling pathway GO:0090081 1 0.115
growth GO:0040007 202 0.114
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.114
regulation of endopeptidase activity GO:0052548 170 0.112
Rat
positive regulation of actin filament bundle assembly GO:0032233 25 0.111
regulation of actin cytoskeleton organization GO:0032956 116 0.110
camp biosynthetic process GO:0006171 47 0.110
regulation of polysaccharide biosynthetic process GO:0032885 20 0.109
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.107
regulation of nucleoside metabolic process GO:0009118 209 0.105
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.104
regulation of cellular amino acid metabolic process GO:0006521 6 0.104
viral life cycle GO:0019058 132 0.104
magnesium ion transport GO:0015693 3 0.102
actin filament based process GO:0030029 224 0.102
regulation of cellular component movement GO:0051270 334 0.101
response to bacterium GO:0009617 144 0.100
protein processing GO:0016485 226 0.100
Rat
lens morphogenesis in camera type eye GO:0002089 2 0.100
defense response to bacterium GO:0042742 63 0.100
regulation of stress activated mapk cascade GO:0032872 84 0.100
organelle localization GO:0051640 84 0.099
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.098
negative regulation of angiogenesis GO:0016525 39 0.098
actin filament bundle assembly GO:0051017 54 0.098
defense response GO:0006952 315 0.098
negative regulation of epithelial cell migration GO:0010633 38 0.097
positive regulation of nucleoside metabolic process GO:0045979 186 0.097
striated muscle cell apoptotic process GO:0010658 3 0.097
organophosphate catabolic process GO:0046434 430 0.096
regulation of establishment of protein localization GO:0070201 242 0.096
negative regulation of hydrolase activity GO:0051346 182 0.095
Rat
organ induction GO:0001759 4 0.095
neurotransmitter secretion GO:0007269 4 0.094
posttranscriptional regulation of gene expression GO:0010608 213 0.094
gtp catabolic process GO:0006184 237 0.094
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.094
Rat
regulation of defense response GO:0031347 154 0.093
nucleoside phosphate biosynthetic process GO:1901293 109 0.092
regulation of multicellular organism growth GO:0040014 8 0.092
hypoxia inducible factor 1alpha signaling pathway GO:0097411 3 0.092
cellular response to nutrient levels GO:0031669 69 0.091
receptor metabolic process GO:0043112 81 0.091
negative regulation of developmental process GO:0051093 247 0.091
regulation of ruffle assembly GO:1900027 8 0.091
system process GO:0003008 349 0.090
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.090
protein acetylation GO:0006473 116 0.089
regulation of nucleotide metabolic process GO:0006140 269 0.089
cortical cytoskeleton organization GO:0030865 9 0.088
amine metabolic process GO:0009308 44 0.087
histone h4 k12 acetylation GO:0043983 6 0.087
regulation of cell cycle phase transition GO:1901987 126 0.087
glycosyl compound catabolic process GO:1901658 413 0.087
regulation of gene silencing GO:0060968 24 0.087
negative regulation of myeloid cell differentiation GO:0045638 42 0.084
negative regulation of intracellular signal transduction GO:1902532 183 0.084
regulation of axon guidance GO:1902667 3 0.083
zymogen activation GO:0031638 70 0.083
methylation dependent chromatin silencing GO:0006346 3 0.083
angiogenesis GO:0001525 147 0.082
purine nucleoside catabolic process GO:0006152 398 0.082
actin filament organization GO:0007015 128 0.082
methylation GO:0032259 106 0.081
regulation of intracellular transport GO:0032386 195 0.081
purine ribonucleotide catabolic process GO:0009154 404 0.080
maintenance of location GO:0051235 112 0.078
embryonic placenta development GO:0001892 1 0.078
pharynx development GO:0060465 1 0.078
response to cytokine GO:0034097 232 0.077
regulation of protein catabolic process GO:0042176 155 0.077
positive regulation of cell motility GO:2000147 177 0.077
divalent metal ion transport GO:0070838 152 0.075
negative regulation of cellular component organization GO:0051129 235 0.075
hair cell differentiation GO:0035315 2 0.073
regulation of protein localization GO:0032880 296 0.073
endodermal mesodermal cell signaling involved in heart induction GO:0003134 3 0.073
hemopoiesis GO:0030097 180 0.071
histone phosphorylation GO:0016572 16 0.070
posttranscriptional gene silencing GO:0016441 25 0.070
positive regulation of protein complex assembly GO:0031334 86 0.070
regulation of vesicle mediated transport GO:0060627 130 0.070
regulation of growth rate GO:0040009 1 0.070
regulation of chromosome organization GO:0033044 103 0.070
regulation of blood circulation GO:1903522 59 0.070
regulation of chromatin organization GO:1902275 56 0.069
positive regulation of homeostatic process GO:0032846 47 0.069
response to insulin GO:0032868 45 0.069
gene silencing by mirna GO:0035195 23 0.069
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.068
defense response to gram negative bacterium GO:0050829 14 0.067
cortical actin cytoskeleton organization GO:0030866 9 0.066
negative regulation of protein modification process GO:0031400 200 0.066
compound eye development GO:0048749 1 0.066
response to organonitrogen compound GO:0010243 156 0.066
eye morphogenesis GO:0048592 16 0.064
modification by host of symbiont morphology or physiology GO:0051851 26 0.063
exocytosis GO:0006887 71 0.063
phospholipid metabolic process GO:0006644 99 0.063
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.063
response to peptide GO:1901652 65 0.063
lipid metabolic process GO:0006629 381 0.062
negative regulation of mitotic cell cycle GO:0045930 102 0.062
positive regulation of endopeptidase activity GO:0010950 84 0.061
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.061
regulation of actin filament bundle assembly GO:0032231 36 0.061
negative regulation of phosphorus metabolic process GO:0010563 267 0.060
metencephalon development GO:0022037 2 0.060
microtubule based process GO:0007017 210 0.060
cellular response to growth factor stimulus GO:0071363 197 0.058
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.058
peptidyl lysine modification GO:0018205 144 0.058
negative regulation of gene silencing by mirna GO:0060965 3 0.057
protein glycosylation GO:0006486 62 0.057
chromatin remodeling GO:0006338 55 0.057
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.057
regulation of secretion by cell GO:1903530 177 0.056
negative regulation of cellular amine metabolic process GO:0033239 3 0.056
dna damage response detection of dna damage GO:0042769 3 0.056
positive regulation of secretion by cell GO:1903532 108 0.055
regulation of homeostatic process GO:0032844 121 0.055
apoptotic signaling pathway GO:0097190 268 0.054
regulation of cell projection organization GO:0031344 107 0.054
negative regulation of phosphate metabolic process GO:0045936 267 0.054
negative regulation of protein maturation GO:1903318 142 0.054
Rat
negative regulation of proteolysis GO:0045861 132 0.054
Rat
purine nucleotide biosynthetic process GO:0006164 84 0.053
chemotaxis GO:0006935 157 0.053
associative learning GO:0008306 1 0.053
Mouse
regulation of atp metabolic process GO:1903578 29 0.053
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.052
regulation of protein processing GO:0070613 150 0.052
Rat
purine nucleotide catabolic process GO:0006195 405 0.052
positive regulation of organ growth GO:0046622 2 0.052
endodermal cell fate specification GO:0001714 4 0.051
sensory organ development GO:0007423 52 0.051
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.051
autophagy GO:0006914 88 0.050
mesenchymal cell differentiation GO:0048762 52 0.050
negative regulation of mapk cascade GO:0043409 56 0.050
cytoplasmic mrna processing body assembly GO:0033962 10 0.050
regulation of peptidase activity GO:0052547 180 0.050
Rat
multicellular organismal aging GO:0010259 3 0.050
Mouse
embryo development GO:0009790 123 0.049
Mouse
tachykinin receptor signaling pathway GO:0007217 3 0.049
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.049
circulatory system development GO:0072359 262 0.049
regulation of organ formation GO:0003156 4 0.049
pericardium development GO:0060039 2 0.049
negative regulation of cell proliferation GO:0008285 228 0.049
epidermis development GO:0008544 59 0.048
filopodium assembly GO:0046847 18 0.048
cellular response to radiation GO:0071478 65 0.048
regulation of dna binding GO:0051101 37 0.048
protein oligomerization GO:0051259 173 0.048
pyrimidine containing compound catabolic process GO:0072529 13 0.048
regulation of system process GO:0044057 101 0.048
regulation of actin polymerization or depolymerization GO:0008064 56 0.047
regulation of cell differentiation GO:0045595 393 0.047
positive regulation of nucleotide catabolic process GO:0030813 185 0.047
response to starvation GO:0042594 59 0.046
limb development GO:0060173 23 0.046
heart induction GO:0003129 4 0.046
osteoclast differentiation GO:0030316 21 0.045
heart process GO:0003015 62 0.045
negative regulation of catabolic process GO:0009895 104 0.045
cellular response to extracellular stimulus GO:0031668 72 0.045
protein localization to organelle GO:0033365 280 0.045
Mouse
regulation of heart contraction GO:0008016 50 0.044
secretion by cell GO:0032940 226 0.044
Mouse
regulation of synaptic vesicle exocytosis GO:2000300 2 0.044
negative regulation of cardiac muscle cell apoptotic process GO:0010667 2 0.044
behavior GO:0007610 112 0.044
Mouse
hyaluronan metabolic process GO:0030212 15 0.043
blood vessel development GO:0001568 172 0.043
release of sequestered calcium ion into cytosol GO:0051209 41 0.043
positive regulation of peptidase activity GO:0010952 88 0.043
stem cell development GO:0048864 69 0.043
negative regulation of blood vessel morphogenesis GO:2000181 41 0.042
regulation of cell growth GO:0001558 135 0.042
vasculature development GO:0001944 181 0.042
peptidyl threonine phosphorylation GO:0018107 41 0.042
regulation of canonical wnt signaling pathway GO:0060828 88 0.042
response to increased oxygen levels GO:0036296 4 0.042
histone h3 k14 acetylation GO:0044154 2 0.042
protein secretion GO:0009306 98 0.042
sex differentiation GO:0007548 45 0.041
actin polymerization or depolymerization GO:0008154 56 0.041
cardiac right ventricle morphogenesis GO:0003215 3 0.041
positive regulation of cytokine production GO:0001819 167 0.041
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.041
cellular carbohydrate metabolic process GO:0044262 84 0.040
positive regulation of developmental growth GO:0048639 16 0.040
epidermal cell differentiation GO:0009913 45 0.040
positive regulation of intracellular protein transport GO:0090316 76 0.040
nuclear transport GO:0051169 179 0.040
Mouse
response to decreased oxygen levels GO:0036293 96 0.040
positive regulation of binding GO:0051099 45 0.040
negative regulation of ossification GO:0030279 21 0.039
small molecule biosynthetic process GO:0044283 157 0.039
Mouse
positive regulation of protein transport GO:0051222 135 0.039
negative regulation of blood circulation GO:1903523 4 0.038
endoderm formation GO:0001706 33 0.038
regulation of neural precursor cell proliferation GO:2000177 4 0.038
regulation of carbohydrate biosynthetic process GO:0043255 27 0.038
protein dna complex assembly GO:0065004 64 0.038
positive regulation of chromosome organization GO:2001252 41 0.037
regulation of phospholipase activity GO:0010517 26 0.037
glycosylation GO:0070085 71 0.037
negative regulation of gene silencing by rna GO:0060967 3 0.037
metal ion homeostasis GO:0055065 169 0.037
Mouse
response to hyperoxia GO:0055093 4 0.037
embryonic morphogenesis GO:0048598 85 0.037
Mouse
focal adhesion assembly GO:0048041 30 0.036
aminoglycan biosynthetic process GO:0006023 29 0.036
negative regulation of phosphorylation GO:0042326 174 0.036
regulation of autophagy GO:0010506 52 0.036
cell morphogenesis GO:0000902 296 0.036
negative regulation of cell cycle GO:0045786 193 0.036
cardiac epithelial to mesenchymal transition GO:0060317 3 0.036
epithelial cell differentiation GO:0030855 141 0.036
lipid homeostasis GO:0055088 39 0.036
spinal cord development GO:0021510 4 0.035
positive regulation of transcription by galactose GO:0000411 1 0.035
positive regulation of innate immune response GO:0045089 79 0.035
somatic stem cell maintenance GO:0035019 4 0.035
regulation of protein kinase activity GO:0045859 289 0.035
cytokinesis checkpoint GO:0031565 3 0.035
regulation of cellular response to drug GO:2001038 2 0.034
mitotic cytokinesis GO:0000281 19 0.034
cellular macromolecule catabolic process GO:0044265 380 0.034
response to nutrient levels GO:0031667 81 0.034
sensory organ morphogenesis GO:0090596 21 0.034
neurogenesis GO:0022008 169 0.034
Mouse
regulation of protein serine threonine kinase activity GO:0071900 179 0.034
regulation of neuron death GO:1901214 56 0.034
Mouse
regulation of heart morphogenesis GO:2000826 4 0.034
purine nucleoside monophosphate metabolic process GO:0009126 186 0.034
modulation by host of symbiont transcription GO:0052472 20 0.034
response to peptide hormone GO:0043434 61 0.034
synaptic vesicle recycling GO:0036465 3 0.033
rhythmic process GO:0048511 31 0.033
negative regulation of transcription by competitive promoter binding GO:0010944 8 0.033
neuroblast proliferation GO:0007405 4 0.033
positive regulation of myeloid cell differentiation GO:0045639 39 0.033
establishment of synaptic vesicle localization GO:0097480 5 0.033
protein maturation GO:0051604 233 0.033
Rat
regulation of developmental growth GO:0048638 30 0.033
regulation of chemotaxis GO:0050920 74 0.033
regulation of protein transport GO:0051223 213 0.032
negative regulation of protein processing GO:0010955 142 0.032
Rat
activation of cysteine type endopeptidase activity GO:0097202 57 0.032
hormone secretion GO:0046879 65 0.032
Mouse
muscle hypertrophy in response to stress GO:0003299 4 0.032
ribonucleotide catabolic process GO:0009261 405 0.032
developmental programmed cell death GO:0010623 3 0.032
positive regulation of cell development GO:0010720 92 0.032
modification of morphology or physiology of other organism GO:0035821 43 0.032
chromatin mediated maintenance of transcription GO:0048096 2 0.032
mitochondrion organization GO:0007005 156 0.031
Mouse
cell cycle phase transition GO:0044770 173 0.031
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.031
negative regulation of g0 to g1 transition GO:0070317 2 0.031
response to organic cyclic compound GO:0014070 204 0.031
fat cell differentiation GO:0045444 32 0.031
regulation of erythrocyte differentiation GO:0045646 17 0.031
histone h3 s10 phosphorylation GO:0043987 3 0.031
regulation of response to dna damage stimulus GO:2001020 94 0.031
response to oxygen containing compound GO:1901700 369 0.030
regulation of cytoplasmic transport GO:1903649 149 0.030
positive regulation of stress fiber assembly GO:0051496 22 0.030
positive regulation of ion transport GO:0043270 87 0.030
positive regulation of ras gtpase activity GO:0032320 117 0.030
trophectodermal cell differentiation GO:0001829 3 0.030
morphogenesis of embryonic epithelium GO:0016331 4 0.030
Mouse
response to mechanical stimulus GO:0009612 51 0.030
cell cell signaling GO:0007267 155 0.030
Mouse
negative regulation of protein catabolic process GO:0042177 59 0.030
adherens junction organization GO:0034332 36 0.030
positive regulation of histone modification GO:0031058 29 0.029
golgi organization GO:0007030 38 0.029
divalent inorganic cation transport GO:0072511 158 0.029
positive regulation of cell differentiation GO:0045597 211 0.028
positive regulation of defense response GO:0031349 87 0.028
negative regulation of protein complex assembly GO:0031333 43 0.028
regulation of atpase activity GO:0043462 25 0.028
positive regulation of smad protein import into nucleus GO:0060391 8 0.028
response to hormone GO:0009725 175 0.028
regulation of mesoderm development GO:2000380 4 0.028
regulation of epidermis development GO:0045682 19 0.028
cell division GO:0051301 168 0.028
regulation of chromatin silencing GO:0031935 8 0.028
negative regulation of striated muscle contraction GO:0045988 2 0.028
oogenesis GO:0048477 2 0.028
positive regulation of cholesterol storage GO:0010886 4 0.028
n terminal protein amino acid modification GO:0031365 13 0.028
regulation of behavior GO:0050795 82 0.028
regulation of peptidyl serine phosphorylation GO:0033135 50 0.028
negative regulation of actin filament bundle assembly GO:0032232 9 0.027

HTT disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.326
disease of cellular proliferation DOID:14566 174 0.326
central nervous system disease DOID:331 186 0.314
nervous system disease DOID:863 431 0.314
disease of metabolism DOID:0014667 295 0.051
acquired metabolic disease DOID:0060158 58 0.044
diabetes mellitus DOID:9351 31 0.039
carbohydrate metabolism disease DOID:0050013 32 0.039
glucose metabolism disease DOID:4194 32 0.039
neurodegenerative disease DOID:1289 102 0.029