|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
1.000
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
1.000
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
1.000
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
1.000
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
1.000
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
1.000
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
1.000
|
Rat |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
1.000
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
1.000
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
1.000
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
1.000
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
1.000
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
1.000
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
1.000
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
1.000
|
Rat |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
1.000
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
1.000
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.999
|
Mouse Rat Fly |
|
|
negative regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress
|
GO:1990441 |
1 |
0.999
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.999
|
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
7 |
0.999
|
Fly |
|
|
axon regeneration
|
GO:0031103 |
1 |
0.999
|
Mouse |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.999
|
Mouse |
|
|
response to metal ion
|
GO:0010038 |
84 |
0.999
|
Zebrafish Mouse |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.999
|
Fly |
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.999
|
Human Rat |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.999
|
Mouse Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.999
|
Rat Worm Fly |
|
|
regeneration
|
GO:0031099 |
4 |
0.998
|
Mouse |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.998
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.998
|
Mouse |
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.998
|
Mouse |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.998
|
Mouse Rat |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.998
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.998
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.997
|
Rat |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.997
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.996
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.996
|
Mouse |
|
|
wound healing
|
GO:0042060 |
115 |
0.996
|
Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.996
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.996
|
Mouse |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.996
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.996
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.995
|
Mouse Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.995
|
Rat |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.995
|
Rat |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.995
|
Rat Worm Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.995
|
Rat |
|
|
histone modification
|
GO:0016570 |
251 |
0.994
|
Human |
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.994
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.993
|
Mouse Rat |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.993
|
Human Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.993
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.993
|
Rat |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.991
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.991
|
Rat |
|
|
membrane organization
|
GO:0061024 |
292 |
0.990
|
Human |
|
|
protein acetylation
|
GO:0006473 |
116 |
0.989
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.989
|
Mouse Rat |
|
|
response to other organism
|
GO:0051707 |
261 |
0.989
|
Rat Worm Fly |
|
|
negative regulation by host of viral transcription
|
GO:0043922 |
12 |
0.989
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.988
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.988
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.988
|
Fly |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.988
|
Rat Worm |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.987
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.987
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.986
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.985
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.985
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.984
|
Rat |
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.984
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.984
|
Human |
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.984
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.983
|
Rat |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.983
|
Human |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.983
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.983
|
Human |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.982
|
Human |
|
|
response to wounding
|
GO:0009611 |
168 |
0.981
|
Mouse Fly |
|
|
histone acetylation
|
GO:0016573 |
93 |
0.980
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.980
|
Mouse Rat |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.979
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.978
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.977
|
Rat |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.977
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.977
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.976
|
Worm Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.976
|
Rat |
|
|
nervous system development
|
GO:0007399 |
293 |
0.975
|
Mouse Fly |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.973
|
Zebrafish Mouse Rat |
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.973
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.973
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.973
|
Rat |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.971
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.970
|
Fly |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.969
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.969
|
Mouse |
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.968
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.967
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.966
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.965
|
Human |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.964
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.963
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.962
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.961
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.961
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.961
|
Fly |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.960
|
|
|
|
positive regulation by host of viral transcription
|
GO:0043923 |
11 |
0.960
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.960
|
Rat |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.955
|
Human |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.952
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.951
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.949
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.948
|
Fly |
|
|
digestive system development
|
GO:0055123 |
75 |
0.947
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.947
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.945
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.942
|
Fly |
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.941
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.938
|
Human |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
23 |
0.934
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.932
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
6 |
0.930
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.929
|
Human Rat |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.925
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.923
|
Rat |
|
|
positive regulation of mitochondrial membrane permeability
|
GO:0035794 |
17 |
0.923
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.922
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.920
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.915
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.914
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.911
|
Mouse |
|
|
positive regulation of hemoglobin biosynthetic process
|
GO:0046985 |
1 |
0.910
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.906
|
Fly |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.905
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.903
|
Fly |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.902
|
Human Rat |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.902
|
Mouse |
|
|
positive regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902110 |
16 |
0.899
|
Human |
|
|
positive regulation of viral transcription
|
GO:0050434 |
13 |
0.896
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.888
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
8 |
0.887
|
Rat |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.886
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.885
|
Mouse Rat |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.881
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.881
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.880
|
Human |
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.878
|
Rat |
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.874
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.874
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.872
|
Mouse Rat |
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.872
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.870
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.868
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.867
|
|
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.866
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.865
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.865
|
Rat |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.863
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.862
|
Rat Worm |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.862
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.858
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
106 |
0.856
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.854
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.853
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.852
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.851
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.851
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.850
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.848
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.847
|
Mouse |
|
|
negative regulation of viral transcription
|
GO:0032897 |
23 |
0.847
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.833
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.833
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.831
|
Worm Fly |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.830
|
|
|
|
aging
|
GO:0007568 |
66 |
0.829
|
Rat Fly |
|
|
response to lipid
|
GO:0033993 |
206 |
0.822
|
Rat |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.821
|
Mouse Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.819
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.815
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.812
|
Worm Fly |
|
|
response to drug
|
GO:0042493 |
81 |
0.809
|
Mouse Rat |
|
|
viral process
|
GO:0016032 |
146 |
0.808
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.802
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.801
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.800
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.797
|
Mouse Rat |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.794
|
Mouse Rat |
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.794
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.792
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.789
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.786
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.778
|
Mouse |
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.777
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.777
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.776
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.776
|
Human |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.773
|
Rat |
|
|
phagocytosis
|
GO:0006909 |
42 |
0.770
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.770
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.769
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.765
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.753
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.748
|
Mouse |
|
|
associative learning
|
GO:0008306 |
1 |
0.747
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.745
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.743
|
Worm Fly |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.739
|
Rat |
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.737
|
Mouse |
|
|
system process
|
GO:0003008 |
349 |
0.737
|
Rat Fly |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.736
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.735
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.733
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.733
|
Human |
|
|
response to camp
|
GO:0051591 |
25 |
0.732
|
Rat |
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.718
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.717
|
|
|
|
growth
|
GO:0040007 |
202 |
0.714
|
Fly |
|
|
ossification
|
GO:0001503 |
121 |
0.714
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.713
|
Mouse |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.713
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.710
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.709
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.707
|
Mouse Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.706
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0097201 |
5 |
0.706
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.699
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.698
|
Human |
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.696
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.695
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.694
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.694
|
|
|
|
jun phosphorylation
|
GO:0007258 |
28 |
0.693
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.691
|
Human |
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.687
|
Rat |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.686
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.685
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.682
|
Mouse |
|
|
heart process
|
GO:0003015 |
62 |
0.679
|
Fly |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.677
|
Fly |
|
|
cytokine production
|
GO:0001816 |
247 |
0.676
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.676
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.670
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.668
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.668
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.665
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.659
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.651
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.648
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.646
|
Rat |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.646
|
|
|
|
mitochondrial outer membrane permeabilization involved in programmed cell death
|
GO:1902686 |
16 |
0.643
|
Human |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.639
|
Rat |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.639
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.638
|
Fly |
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.631
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.630
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.630
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.625
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.615
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.612
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.611
|
Fly |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.608
|
|
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.606
|
Human |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.603
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.602
|
Mouse |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.601
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.600
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.600
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.599
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.598
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.591
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.591
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.586
|
|
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.585
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
26 |
0.580
|
|
|
|
regulation of hemoglobin biosynthetic process
|
GO:0046984 |
1 |
0.580
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.575
|
Human |
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
19 |
0.572
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.566
|
Worm Fly |
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.558
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.557
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.554
|
|
|
|
hemoglobin biosynthetic process
|
GO:0042541 |
3 |
0.549
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.546
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.537
|
Fly |
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.534
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.530
|
|
|
|
muscle cell development
|
GO:0055001 |
29 |
0.527
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.525
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
9 |
0.525
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.515
|
Fly |
|
|
axon development
|
GO:0061564 |
34 |
0.515
|
Mouse |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.511
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.511
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.507
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.506
|
Mouse Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.506
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.503
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.503
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.499
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.495
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.493
|
Human |
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.488
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.488
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.486
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.476
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.475
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.474
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.472
|
Rat |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.471
|
|
|
|
post embryonic hemopoiesis
|
GO:0035166 |
1 |
0.467
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.467
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.463
|
Fly |
|
|
skeletal muscle tissue development
|
GO:0007519 |
24 |
0.460
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.456
|
Mouse Rat |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.453
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.452
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.452
|
Rat |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.452
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.452
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.449
|
|
|
|
positive regulation of blood circulation
|
GO:1903524 |
12 |
0.449
|
Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.448
|
Rat |
|
|
response to antibiotic
|
GO:0046677 |
15 |
0.448
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.447
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.441
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.438
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.435
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.433
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.432
|
Rat |
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.429
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.429
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.426
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.425
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.417
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.415
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.414
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.412
|
Fly |
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.409
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.407
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.404
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.403
|
Human |
|
|
modulation of transcription in other organism involved in symbiotic interaction
|
GO:0052312 |
20 |
0.401
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.395
|
Mouse Rat |
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.390
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.387
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.383
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.379
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.377
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.377
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.377
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.374
|
|
|
|
negative regulation of response to biotic stimulus
|
GO:0002832 |
18 |
0.370
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.367
|
|
|
|
positive regulation of autophagy
|
GO:0010508 |
24 |
0.365
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.362
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.362
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.361
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.361
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.361
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.359
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.354
|
Human |
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.350
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.348
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.347
|
Human |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.346
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.346
|
Worm Fly |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.344
|
Human |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.343
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.342
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.340
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.337
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.337
|
Rat |
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.336
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.335
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.334
|
|
|
|
positive regulation of deacetylase activity
|
GO:0090045 |
6 |
0.332
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.329
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.324
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.324
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.320
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.320
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.317
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.311
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.310
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.308
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.307
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.306
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.306
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.306
|
|
|
|
ectodermal digestive tract development
|
GO:0007439 |
1 |
0.303
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.303
|
Mouse |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.298
|
Human |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.293
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.293
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.293
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.292
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.292
|
Human |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.284
|
|
|
|
negative regulation of chemokine c x c motif ligand 2 production
|
GO:2000342 |
1 |
0.281
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.280
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.276
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.276
|
|
|
|
heart contraction
|
GO:0060047 |
62 |
0.275
|
Fly |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.275
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.274
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
34 |
0.273
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.272
|
|
|
|
foam cell differentiation
|
GO:0090077 |
15 |
0.270
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.270
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.270
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.269
|
Rat |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.267
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.262
|
Mouse Rat |
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.262
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.260
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.259
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.258
|
Worm Fly |
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.257
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.256
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.256
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.255
|
Fly |
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.253
|
Mouse Rat |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.253
|
|
|
|
muscle fiber development
|
GO:0048747 |
16 |
0.253
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.252
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.251
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.251
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.249
|
|
|
|
response to progesterone
|
GO:0032570 |
5 |
0.249
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.249
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.247
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
9 |
0.247
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.245
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.244
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.244
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.242
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.239
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.239
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.238
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.238
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.232
|
Fly |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.231
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.231
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.230
|
Rat |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.230
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.230
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.229
|
Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.224
|
Mouse Rat |
|
|
response to ketone
|
GO:1901654 |
19 |
0.224
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.223
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.222
|
|
|
|
striated muscle cell development
|
GO:0055002 |
27 |
0.218
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.217
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.216
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.216
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.216
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.213
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.213
|
|
|
|
interaction with symbiont
|
GO:0051702 |
26 |
0.212
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.212
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.210
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.209
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.207
|
Rat |
|
|
maternal placenta development
|
GO:0001893 |
5 |
0.204
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.204
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.204
|
Fly |
|
|
defense response
|
GO:0006952 |
315 |
0.202
|
Worm |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.202
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.201
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.200
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.196
|
|
|
|
memory
|
GO:0007613 |
3 |
0.194
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.194
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.193
|
Fly |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.193
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.193
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.191
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.189
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.189
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.187
|
|
|
|
response to organophosphorus
|
GO:0046683 |
41 |
0.186
|
Rat |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.186
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.182
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.179
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.177
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.176
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.175
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.173
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.172
|
Rat |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.171
|
|
|
|
ectodermal digestive tract morphogenesis
|
GO:0048567 |
1 |
0.171
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.165
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.164
|
|
