Homo sapiens

42 known processes

LDLR

low density lipoprotein receptor

(Aliases: FH,LDLCQ2,FHC)

LDLR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 381 0.943
Mouse
cellular ketone metabolic process GO:0042180 80 0.855
glycerolipid metabolic process GO:0046486 107 0.776
Mouse
lipid biosynthetic process GO:0008610 177 0.762
Mouse
cellular lipid metabolic process GO:0044255 303 0.744
Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.729
cholesterol homeostasis GO:0042632 28 0.687
cholesterol transport GO:0030301 39 0.641
regulation of plasma lipoprotein particle levels GO:0097006 32 0.641
chemical homeostasis GO:0048878 306 0.630
small molecule biosynthetic process GO:0044283 157 0.622
sterol homeostasis GO:0055092 28 0.600
triglyceride metabolic process GO:0006641 23 0.575
Mouse
negative regulation of lipid metabolic process GO:0045833 38 0.573
alcohol metabolic process GO:0006066 114 0.544
Mouse
vasculature development GO:0001944 181 0.517
positive regulation of cellular component organization GO:0051130 376 0.508
cellular amine metabolic process GO:0044106 41 0.485
Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.468
Mouse
steroid metabolic process GO:0008202 94 0.456
Mouse
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.453
positive regulation of cholesterol storage GO:0010886 4 0.442
regulation of protein kinase activity GO:0045859 289 0.418
positive regulation of developmental process GO:0051094 314 0.415
positive regulation of behavior GO:0048520 60 0.394
regulation of cell migration GO:0030334 289 0.392
sterol metabolic process GO:0016125 28 0.387
Mouse
cell chemotaxis GO:0060326 112 0.380
regulation of cell differentiation GO:0045595 393 0.370
patterning of blood vessels GO:0001569 2 0.370
post embryonic development GO:0009791 2 0.362
cholesterol metabolic process GO:0008203 28 0.342
Mouse
acylglycerol metabolic process GO:0006639 27 0.334
Mouse
organic hydroxy compound metabolic process GO:1901615 147 0.332
Mouse
steroid biosynthetic process GO:0006694 46 0.331
receptor catabolic process GO:0032801 11 0.329
negative regulation of multicellular organismal process GO:0051241 317 0.327
neutral lipid metabolic process GO:0006638 27 0.317
Mouse
response to abiotic stimulus GO:0009628 336 0.313
Rat
regulation of lipid metabolic process GO:0019216 96 0.304
Mouse
blood vessel development GO:0001568 172 0.294
organophosphate biosynthetic process GO:0090407 163 0.290
regulation of lipid biosynthetic process GO:0046890 47 0.288
Mouse
regulation of kinase activity GO:0043549 314 0.275
locomotory behavior GO:0007626 1 0.275
regulation of response to external stimulus GO:0032101 222 0.272
cyclic nucleotide metabolic process GO:0009187 82 0.265
regulation of mapk cascade GO:0043408 262 0.258
positive regulation of hematopoietic progenitor cell differentiation GO:1901534 5 0.258
protein processing GO:0016485 226 0.248
chemotaxis GO:0006935 157 0.247
regulation of cellular amino acid metabolic process GO:0006521 6 0.242
positive regulation of cell motility GO:2000147 177 0.239
lipid homeostasis GO:0055088 39 0.239
positive regulation of cell differentiation GO:0045597 211 0.235
regulation of cell motility GO:2000145 299 0.229
cardiovascular system development GO:0072358 262 0.227
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.225
amine metabolic process GO:0009308 44 0.216
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.215
response to cytokine GO:0034097 232 0.214
lipid transport GO:0006869 90 0.212
regulation of chemotaxis GO:0050920 74 0.212
defense response GO:0006952 315 0.212
mapk cascade GO:0000165 288 0.211
protein catabolic process GO:0030163 325 0.207
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.207
cellular amino acid metabolic process GO:0006520 116 0.206
negative regulation of phosphate metabolic process GO:0045936 267 0.202
male sex differentiation GO:0046661 25 0.200
receptor internalization GO:0031623 43 0.199
alcohol biosynthetic process GO:0046165 52 0.198
sterol transport GO:0015918 39 0.198
regulation of glomerular mesangial cell proliferation GO:0072124 3 0.198
anatomical structure formation involved in morphogenesis GO:0048646 284 0.187
maintenance of location GO:0051235 112 0.184
regulation of cell adhesion GO:0030155 166 0.183
epithelial cell migration GO:0010631 119 0.180
response to drug GO:0042493 81 0.179
regulation of locomotion GO:0040012 329 0.177
receptor metabolic process GO:0043112 81 0.176
wound healing GO:0042060 115 0.173
vascular wound healing GO:0061042 4 0.171
positive regulation of cellular amine metabolic process GO:0033240 7 0.170
regulation of transferase activity GO:0051338 355 0.168
g protein coupled receptor signaling pathway GO:0007186 207 0.165
response to oxygen containing compound GO:1901700 369 0.163
Rat
positive regulation of lipid metabolic process GO:0045834 50 0.163
Mouse
protein maturation GO:0051604 233 0.161
cell type specific apoptotic process GO:0097285 125 0.160
peptidyl tyrosine modification GO:0018212 170 0.160
oogenesis GO:0048477 2 0.159
positive regulation of immune system process GO:0002684 283 0.158
circulatory system development GO:0072359 262 0.157
nervous system development GO:0007399 293 0.155
neuron projection development GO:0031175 106 0.154
positive regulation of transport GO:0051050 336 0.153
monocarboxylic acid biosynthetic process GO:0072330 67 0.153
regulation of receptor mediated endocytosis GO:0048259 32 0.152
glycerolipid biosynthetic process GO:0045017 51 0.152
Mouse
signal transduction by phosphorylation GO:0023014 297 0.152
tissue migration GO:0090130 119 0.151
cellular response to cytokine stimulus GO:0071345 181 0.151
regulation of cytokine production GO:0001817 232 0.151
regulation of protein serine threonine kinase activity GO:0071900 179 0.150
enzyme linked receptor protein signaling pathway GO:0007167 303 0.150
cellular response to oxygen containing compound GO:1901701 276 0.149
negative regulation of protein metabolic process GO:0051248 391 0.147
positive regulation of cell proliferation GO:0008284 301 0.147
regulation of glomerulus development GO:0090192 3 0.147
regulation of angiogenesis GO:0045765 92 0.146
angiogenesis GO:0001525 147 0.144
system process GO:0003008 349 0.144
negative regulation of hemostasis GO:1900047 22 0.144
cell adhesion GO:0007155 325 0.143
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.140
regulation of receptor internalization GO:0002090 15 0.140
positive regulation of locomotion GO:0040017 186 0.139
cellular cation homeostasis GO:0030003 163 0.139
organic hydroxy compound biosynthetic process GO:1901617 71 0.138
positive regulation of lipid storage GO:0010884 10 0.137
endothelial cell migration GO:0043542 86 0.135
biological adhesion GO:0022610 331 0.134
divalent metal ion transport GO:0070838 152 0.133
response to other organism GO:0051707 261 0.133
vesicle mediated transport GO:0016192 371 0.133
cell morphogenesis GO:0000902 296 0.131
response to decreased oxygen levels GO:0036293 96 0.130
Rat
regulation of leukocyte chemotaxis GO:0002688 46 0.128
regulation of epithelial cell migration GO:0010632 93 0.128
transmembrane transport GO:0055085 399 0.128
Mouse
positive regulation of receptor internalization GO:0002092 12 0.127
angiogenesis involved in wound healing GO:0060055 4 0.127
plasma lipoprotein particle clearance GO:0034381 16 0.127
regulation of vesicle mediated transport GO:0060627 130 0.126
cellular response to growth factor stimulus GO:0071363 197 0.122
fatty acid metabolic process GO:0006631 115 0.119
regulation of cellular component movement GO:0051270 334 0.119
positive regulation of neuron death GO:1901216 14 0.119
positive regulation of apoptotic process GO:0043065 246 0.118
peptidyl tyrosine phosphorylation GO:0018108 170 0.117
regulation of cellular component biogenesis GO:0044087 281 0.116
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 0.116
response to growth factor GO:0070848 205 0.116
single organism cellular localization GO:1902580 332 0.115
positive regulation of cell migration GO:0030335 172 0.114
sterol biosynthetic process GO:0016126 10 0.113
positive regulation of programmed cell death GO:0043068 249 0.113
tube development GO:0035295 125 0.112
regulation of cell substrate adhesion GO:0010810 68 0.112
response to peptide GO:1901652 65 0.111
Rat
hematopoietic or lymphoid organ development GO:0048534 186 0.110
leukocyte migration GO:0050900 107 0.109
embryonic morphogenesis GO:0048598 85 0.108
myeloid cell differentiation GO:0030099 117 0.108
innate immune response GO:0045087 178 0.108
cellular response to endogenous stimulus GO:0071495 336 0.107
cell activation GO:0001775 213 0.107
regulation of homeostatic process GO:0032844 121 0.106
Mouse
mitotic cell cycle process GO:1903047 286 0.106
negative regulation of phosphorus metabolic process GO:0010563 267 0.106
regulation of endothelial cell migration GO:0010594 67 0.104
positive regulation of vascular wound healing GO:0035470 1 0.103
ameboidal type cell migration GO:0001667 135 0.103
cytokine mediated signaling pathway GO:0019221 109 0.103
multicellular organismal aging GO:0010259 3 0.101
regulation of endothelial cell proliferation GO:0001936 56 0.101
organ morphogenesis GO:0009887 147 0.101
growth GO:0040007 202 0.100
epithelium development GO:0060429 227 0.100
immune system development GO:0002520 195 0.100
determination of adult lifespan GO:0008340 2 0.099
single organism membrane organization GO:0044802 268 0.099
vascular process in circulatory system GO:0003018 29 0.096
leukocyte chemotaxis GO:0030595 76 0.096
cell morphogenesis involved in differentiation GO:0000904 144 0.094
positive regulation of cell death GO:0010942 263 0.094
negative regulation of catalytic activity GO:0043086 335 0.093
positive regulation of phosphorylation GO:0042327 394 0.093
regulation of carbohydrate metabolic process GO:0006109 54 0.093
organic hydroxy compound transport GO:0015850 63 0.093
regulation of cell growth GO:0001558 135 0.091
lipid localization GO:0010876 106 0.090
cellular component morphogenesis GO:0032989 314 0.090
neuron differentiation GO:0030182 138 0.090
single organism cell adhesion GO:0098602 179 0.089
protein localization to membrane GO:0072657 160 0.089
cell development GO:0048468 328 0.087
cell projection organization GO:0030030 252 0.087
microtubule based process GO:0007017 210 0.086
positive regulation of cell adhesion GO:0045785 84 0.086
response to lipid GO:0033993 206 0.086
Rat
negative regulation of phosphorylation GO:0042326 174 0.086
visual behavior GO:0007632 2 0.085
positive regulation of endocytosis GO:0045807 42 0.085
regulation of anatomical structure morphogenesis GO:0022603 286 0.085
negative regulation of blood coagulation GO:0030195 22 0.085
muscle system process GO:0003012 81 0.084
cation homeostasis GO:0055080 189 0.084
regulation of chemokine production GO:0032642 31 0.084
regulation of cell proliferation involved in kidney development GO:1901722 3 0.083
response to biotic stimulus GO:0009607 276 0.083
positive regulation of lipid biosynthetic process GO:0046889 22 0.083
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 2 0.083
negative regulation of protein processing GO:0010955 142 0.081
phospholipid metabolic process GO:0006644 99 0.081
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.081
negative regulation of apoptotic process GO:0043066 316 0.081
positive regulation of protein kinase activity GO:0045860 190 0.081
actin filament based process GO:0030029 224 0.081
regulation of behavior GO:0050795 82 0.080
extrinsic apoptotic signaling pathway GO:0097191 119 0.079
regulation of cell cycle GO:0051726 393 0.079
endomembrane system organization GO:0010256 196 0.077
taxis GO:0042330 157 0.073
cellular protein catabolic process GO:0044257 261 0.073
purine ribonucleotide biosynthetic process GO:0009152 79 0.073
positive regulation of neuron apoptotic process GO:0043525 8 0.073
ion homeostasis GO:0050801 230 0.072
craniofacial suture morphogenesis GO:0097094 3 0.072
cell junction organization GO:0034330 79 0.072
circulatory system process GO:0003013 113 0.072
ribonucleotide biosynthetic process GO:0009260 81 0.071
muscle contraction GO:0006936 73 0.071
positive regulation of cellular component movement GO:0051272 181 0.071
response to radiation GO:0009314 151 0.070
metal ion homeostasis GO:0055065 169 0.070
ribose phosphate biosynthetic process GO:0046390 82 0.070
dephosphorylation GO:0016311 209 0.070
response to oxygen levels GO:0070482 100 0.069
Rat
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.069
negative regulation of cell differentiation GO:0045596 171 0.069
negative regulation of peptidase activity GO:0010466 91 0.068
regulation of steroid biosynthetic process GO:0050810 23 0.068
endocytosis GO:0006897 159 0.067
cell growth GO:0016049 160 0.067
positive regulation of chemotaxis GO:0050921 57 0.067
regulation of peptidyl tyrosine autophosphorylation GO:1900084 1 0.066
motor neuron axon guidance GO:0008045 2 0.066
erythrocyte homeostasis GO:0034101 31 0.066
myeloid leukocyte migration GO:0097529 62 0.066
regulation of neuron apoptotic process GO:0043523 35 0.066
regulation of protein processing GO:0070613 150 0.065
cell projection morphogenesis GO:0048858 129 0.065
myeloid leukocyte activation GO:0002274 34 0.064
positive regulation of cell substrate adhesion GO:0010811 37 0.064
regulation of coagulation GO:0050818 44 0.064
cytokine production GO:0001816 247 0.064
negative regulation of transport GO:0051051 176 0.063
regulation of growth GO:0040008 165 0.063
regulation of vascular wound healing GO:0061043 2 0.063
regulation of blood coagulation GO:0030193 42 0.063
apoptotic signaling pathway GO:0097190 268 0.063
hemopoiesis GO:0030097 180 0.062
carbohydrate derivative biosynthetic process GO:1901137 207 0.061
posttranscriptional regulation of gene expression GO:0010608 213 0.061
regulation of defense response GO:0031347 154 0.061
renal system development GO:0072001 63 0.060
cellular response to dna damage stimulus GO:0006974 379 0.060
gland development GO:0048732 48 0.060
regulation of apoptotic signaling pathway GO:2001233 175 0.059
lung alveolus development GO:0048286 4 0.059
regulation of map kinase activity GO:0043405 108 0.059
carboxylic acid biosynthetic process GO:0046394 97 0.059
histone modification GO:0016570 251 0.059
female gamete generation GO:0007292 2 0.058
embryo development GO:0009790 123 0.057
sprouting angiogenesis GO:0002040 29 0.057
regulation of vasculature development GO:1901342 97 0.057
regulation of cellular response to stress GO:0080135 244 0.057
response to hormone GO:0009725 175 0.056
Rat
blood vessel morphogenesis GO:0048514 162 0.055
cell substrate junction assembly GO:0007044 35 0.055
polysaccharide metabolic process GO:0005976 33 0.055
cellular response to peptide hormone stimulus GO:0071375 56 0.055
reactive oxygen species metabolic process GO:0072593 75 0.054
regulation of immune response GO:0050776 201 0.054
negative regulation of lipid biosynthetic process GO:0051055 22 0.054
cellular ion homeostasis GO:0006873 168 0.053
regulation of myeloid cell differentiation GO:0045637 81 0.052
response to external biotic stimulus GO:0043207 261 0.052
cholesterol biosynthetic process GO:0006695 10 0.052
generation of neurons GO:0048699 152 0.052
regulation of endocytosis GO:0030100 72 0.052
regulation of smooth muscle cell migration GO:0014910 15 0.052
negative regulation of cell adhesion GO:0007162 64 0.052
salivary gland morphogenesis GO:0007435 4 0.052
regulation of phosphatase activity GO:0010921 81 0.051
regulation of neuron death GO:1901214 56 0.051
cell substrate adhesion GO:0031589 132 0.051
cellular divalent inorganic cation homeostasis GO:0072503 128 0.051
cellular response to organonitrogen compound GO:0071417 124 0.051
regulation of stress activated mapk cascade GO:0032872 84 0.051
response to low density lipoprotein particle GO:0055098 4 0.051
immune response GO:0006955 307 0.051
regulation of hemostasis GO:1900046 42 0.050
negative regulation of programmed cell death GO:0043069 321 0.050
negative regulation of response to wounding GO:1903035 47 0.050
tissue morphogenesis GO:0048729 96 0.050
response to organonitrogen compound GO:0010243 156 0.050
Rat
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
basophil chemotaxis GO:0002575 1 0.050
positive regulation of response to external stimulus GO:0032103 88 0.049
actin cytoskeleton organization GO:0030036 207 0.049
cerebral cortex cell migration GO:0021795 3 0.049
regulation of protein localization GO:0032880 296 0.049
cellular macromolecule catabolic process GO:0044265 380 0.049
positive regulation of cellular component biogenesis GO:0044089 158 0.049
mitotic cell cycle GO:0000278 326 0.048
negative regulation of transferase activity GO:0051348 124 0.048
positive regulation of mast cell chemotaxis GO:0060754 4 0.048
oxidation reduction process GO:0055114 396 0.048
response to transforming growth factor beta GO:0071559 94 0.048
regulation of mast cell chemotaxis GO:0060753 4 0.048
neuron development GO:0048666 113 0.047
secretion GO:0046903 254 0.047
positive regulation of epithelial cell migration GO:0010634 55 0.047
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.047
negative chemotaxis GO:0050919 11 0.047
nucleoside phosphate biosynthetic process GO:1901293 109 0.046
cerebral cortex radially oriented cell migration GO:0021799 1 0.046
negative regulation of cell death GO:0060548 345 0.046
negative regulation of cholesterol transport GO:0032375 8 0.046
regulation of wound healing GO:0061041 56 0.046
cell projection assembly GO:0030031 126 0.046
regulation of cell cell adhesion GO:0022407 57 0.045
low density lipoprotein particle clearance GO:0034383 8 0.045
mucopolysaccharide metabolic process GO:1903510 27 0.045
cytokine secretion GO:0050663 64 0.045
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.045
cellular response to nitrogen compound GO:1901699 144 0.045
negative regulation of response to external stimulus GO:0032102 83 0.044
negative regulation of proteolysis GO:0045861 132 0.044
intracellular receptor signaling pathway GO:0030522 104 0.044
reproductive system development GO:0061458 56 0.044
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 0.044
rhythmic behavior GO:0007622 2 0.044
regulation of multi organism process GO:0043900 157 0.044
endothelial cell proliferation GO:0001935 65 0.044
membrane organization GO:0061024 292 0.044
establishment of protein localization to membrane GO:0090150 121 0.044
behavior GO:0007610 112 0.044
smooth muscle cell migration GO:0014909 18 0.044
negative regulation of mapk cascade GO:0043409 56 0.044
response to inorganic substance GO:0010035 127 0.043
blood circulation GO:0008015 113 0.043
central nervous system development GO:0007417 123 0.043
positive regulation of histone deacetylase activity GO:1901727 3 0.043
cyclic purine nucleotide metabolic process GO:0052652 60 0.043
inner ear morphogenesis GO:0042472 4 0.043
muscle cell proliferation GO:0033002 35 0.043
cyclic nucleotide biosynthetic process GO:0009190 61 0.043
regulation of secretion GO:0051046 194 0.043
smooth muscle cell proliferation GO:0048659 28 0.043
positive regulation of catabolic process GO:0009896 310 0.043
negative regulation of cell growth GO:0030308 83 0.042
positive regulation of hydrolase activity GO:0051345 331 0.042
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.042
regulation of neural precursor cell proliferation GO:2000177 4 0.042
negative regulation of intracellular signal transduction GO:1902532 183 0.042
regulation of protein catabolic process GO:0042176 155 0.042
regulation of response to wounding GO:1903034 101 0.041
blood vessel endothelial cell migration GO:0043534 42 0.041
calcium ion homeostasis GO:0055074 122 0.041
regulation of axon guidance GO:1902667 3 0.041
regulation of cell morphogenesis GO:0022604 153 0.041
regulation of purine nucleotide metabolic process GO:1900542 264 0.041
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.041
neuron apoptotic process GO:0051402 39 0.041
negative regulation of cell proliferation GO:0008285 228 0.041
neuroblast proliferation GO:0007405 4 0.041
protein autoprocessing GO:0016540 4 0.040
regulation of cholesterol metabolic process GO:0090181 4 0.040
oocyte development GO:0048599 1 0.040
circadian behavior GO:0048512 2 0.040
negative regulation of protein modification process GO:0031400 200 0.040
nucleotide biosynthetic process GO:0009165 109 0.040
cellular carbohydrate metabolic process GO:0044262 84 0.039
single organism reproductive process GO:0044702 98 0.039
cellular homeostasis GO:0019725 196 0.039
positive regulation of secretion by cell GO:1903532 108 0.039
response to extracellular stimulus GO:0009991 85 0.039
actin filament organization GO:0007015 128 0.038
cell part morphogenesis GO:0032990 137 0.038
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.038
negative regulation of sterol transport GO:0032372 8 0.037
jak stat cascade GO:0007259 46 0.037
smooth muscle contraction GO:0006939 14 0.037
associative learning GO:0008306 1 0.037
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.037
epithelium migration GO:0090132 119 0.037
positive regulation of dna metabolic process GO:0051054 73 0.037
pericardium development GO:0060039 2 0.036
cellular response to external stimulus GO:0071496 111 0.036
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 0.036
regulation of protein complex assembly GO:0043254 147 0.036
regulation of muscle system process GO:0090257 53 0.036
negative regulation of wound healing GO:0061045 25 0.036
male genitalia development GO:0030539 1 0.036
mammary gland development GO:0030879 17 0.035
regulation of steroid metabolic process GO:0019218 32 0.035
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.035
stress activated mapk cascade GO:0051403 93 0.035
positive regulation of cell development GO:0010720 92 0.035
response to nutrient levels GO:0031667 81 0.035
cell migration involved in sprouting angiogenesis GO:0002042 19 0.035
organic acid biosynthetic process GO:0016053 97 0.035
monosaccharide metabolic process GO:0005996 74 0.035
urogenital system development GO:0001655 65 0.035
cellular response to insulin stimulus GO:0032869 41 0.035
positive regulation of cytokine production GO:0001819 167 0.034
positive regulation of protein catabolic process GO:0045732 75 0.034
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.034
forebrain generation of neurons GO:0021872 3 0.034
sensory perception of smell GO:0007608 2 0.034
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.034
dna replication GO:0006260 116 0.034
positive regulation of secretion GO:0051047 116 0.034
immune effector process GO:0002252 159 0.034
monocyte chemotaxis GO:0002548 20 0.033
lysosomal transport GO:0007041 33 0.033
protein secretion GO:0009306 98 0.033
sensory organ morphogenesis GO:0090596 21 0.033
negative regulation of cellular component organization GO:0051129 235 0.033
heart contraction GO:0060047 62 0.032
secretion by cell GO:0032940 226 0.032
response to peptide hormone GO:0043434 61 0.032
Rat
positive regulation of leukocyte chemotaxis GO:0002690 38 0.032
regulation of body fluid levels GO:0050878 99 0.032
response to virus GO:0009615 126 0.032
regulation of protein localization to plasma membrane GO:1903076 40 0.032
erythrocyte differentiation GO:0030218 28 0.031
positive regulation of protein kinase c signaling GO:0090037 5 0.031
response to bacterium GO:0009617 144 0.031
phospholipid biosynthetic process GO:0008654 44 0.031
positive regulation of protein complex assembly GO:0031334 86 0.031
mating GO:0007618 1 0.031
positive regulation of hormone biosynthetic process GO:0046886 4 0.031
regulation of secretion by cell GO:1903530 177 0.031
neurogenesis GO:0022008 169 0.031
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.031
cellular response to hormone stimulus GO:0032870 125 0.031
cation transport GO:0006812 331 0.031
positive regulation of neuroblast proliferation GO:0002052 2 0.031
regulation of muscle contraction GO:0006937 45 0.031
post embryonic organ development GO:0048569 1 0.031
positive regulation of growth GO:0045927 58 0.031
carbohydrate metabolic process GO:0005975 207 0.031
positive regulation of hyaluronan biosynthetic process GO:1900127 3 0.031
cellular response to cholesterol GO:0071397 4 0.031
regulation of protein secretion GO:0050708 86 0.030
polysaccharide biosynthetic process GO:0000271 27 0.030
skin development GO:0043588 76 0.030
negative regulation of protein maturation GO:1903318 142 0.030
cell cell junction maintenance GO:0045217 4 0.030
stress activated protein kinase signaling cascade GO:0031098 94 0.030
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.030
low density lipoprotein particle receptor catabolic process GO:0032802 3 0.030
positive regulation of protein phosphorylation GO:0001934 313 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
hemostasis GO:0007599 76 0.029
regulation of leukocyte migration GO:0002685 63 0.029
granulocyte migration GO:0097530 40 0.029
negative regulation of t cell apoptotic process GO:0070233 4 0.029
regulation of adherens junction organization GO:1903391 21 0.029
single organismal cell cell adhesion GO:0016337 148 0.029
response to increased oxygen levels GO:0036296 4 0.029
regulation of establishment of protein localization GO:0070201 242 0.029
cellular response to extracellular stimulus GO:0031668 72 0.029
plasma lipoprotein particle organization GO:0071827 22 0.029
negative regulation of kinase activity GO:0033673 106 0.029
regulation of heart contraction GO:0008016 50 0.029
smooth muscle cell differentiation GO:0051145 8 0.029
negative regulation of developmental process GO:0051093 247 0.029
regulation of protein stability GO:0031647 87 0.029
cell junction maintenance GO:0034331 4 0.029
protein oligomerization GO:0051259 173 0.029
second messenger mediated signaling GO:0019932 78 0.029
regulation of dna templated transcription in response to stress GO:0043620 18 0.029
leukocyte activation GO:0045321 164 0.029
sex differentiation GO:0007548 45 0.028
vasodilation GO:0042311 4 0.028
macromolecular complex remodeling GO:0034367 16 0.028
positive regulation of endothelial cell proliferation GO:0001938 37 0.028
cellular response to lipid GO:0071396 127 0.028
negative regulation of cell fate commitment GO:0010454 3 0.028
purine nucleotide biosynthetic process GO:0006164 84 0.028

LDLR disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.123
inherited metabolic disorder DOID:655 242 0.123
cancer DOID:162 167 0.049
disease of cellular proliferation DOID:14566 174 0.049
central nervous system disease DOID:331 186 0.044
nervous system disease DOID:863 431 0.044
disease of mental health DOID:150 70 0.039
immune system disease DOID:2914 155 0.039
neurodegenerative disease DOID:1289 102 0.033