|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.994
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.990
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.990
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.982
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.978
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.977
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.974
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.973
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.973
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.972
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.970
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.969
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.968
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.966
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.960
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.959
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.958
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.952
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.951
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.948
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.945
|
Fly |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.943
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.933
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.927
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.922
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.920
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.919
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.918
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.918
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.912
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.909
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.905
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.893
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.893
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.892
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.890
|
Fly |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.886
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.885
|
Fly |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.882
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.881
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.872
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.856
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.855
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.847
|
|
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.847
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.847
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.826
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.822
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.821
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.821
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.821
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.815
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.813
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.812
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.785
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.783
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.779
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.775
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.764
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.758
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.753
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.748
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.740
|
Fly |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.734
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.729
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.728
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.725
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.722
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.713
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.711
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.710
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.707
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.700
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.699
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.698
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.695
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.682
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.681
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.673
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.663
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.662
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.655
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.649
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.643
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.637
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.632
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.617
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.611
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.611
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.608
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.608
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.604
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.600
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.599
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.588
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.587
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.587
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.577
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.577
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.573
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.569
|
|
|
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.565
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.557
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.553
|
Fly |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.551
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.547
|
Mouse Fly |
|
|
positive regulation of phagocytosis engulfment
|
GO:0060100 |
1 |
0.544
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.543
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.542
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.538
|
|
|
|
regulation of caveolin mediated endocytosis
|
GO:2001286 |
2 |
0.526
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.519
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.515
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.511
|
Fly |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.506
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.506
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.505
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.504
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.503
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.502
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.500
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.499
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.478
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.478
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.476
|
|
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.473
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.473
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.459
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.459
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.455
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.455
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.449
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.443
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.424
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.424
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.424
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.422
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.421
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.421
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.417
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.408
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.407
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.406
|
|
|
|
memory
|
GO:0007613 |
3 |
0.405
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.400
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.395
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.395
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.393
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.392
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.390
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.390
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.386
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.382
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.380
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.375
|
Fly |
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.370
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.370
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.370
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.365
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.365
|
Mouse |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.360
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.343
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.343
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.343
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.340
|
Fly |
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
8 |
0.335
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.333
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.331
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.325
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.322
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.322
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.320
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.318
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.316
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.308
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.306
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.305
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.298
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.287
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.287
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.284
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.284
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.283
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.282
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.281
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.280
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.280
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.276
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.274
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.270
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.270
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.269
|
Fly |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.266
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.266
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.264
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.262
|
Fly |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.260
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.256
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.248
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.247
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.247
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.244
|
Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.240
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.240
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.239
|
|
|
|
growth
|
GO:0040007 |
202 |
0.238
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.231
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.225
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.223
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.222
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.222
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.222
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.221
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.219
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.217
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.216
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.214
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.214
|
Fly |
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.213
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.212
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.207
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.203
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.203
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.202
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.201
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.199
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.198
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.195
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.193
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.193
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.192
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.192
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.192
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.188
|
Fly |
|
|
oocyte development
|
GO:0048599 |
1 |
0.186
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.186
|
Fly |
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.185
|
Fly |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.185
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.184
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.182
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.182
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.182
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.182
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.181
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.181
|
|
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.180
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.179
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.177
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.176
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.171
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.169
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
12 |
0.169
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.165
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.164
|
|
|
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.164
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.163
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.162
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.157
|
Fly |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.155
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.152
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
23 |
0.150
|
Fly |
|
|
golgi organization
|
GO:0007030 |
38 |
0.148
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.148
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.145
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.140
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.140
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.138
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.135
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.134
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.133
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.132
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.131
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.129
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.128
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.127
|
Fly |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.126
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.125
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.124
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.123
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.122
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.119
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.119
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.118
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.117
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.117
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.117
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.116
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.116
|
Fly |
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.115
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.115
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.112
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.111
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.110
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.109
|
|
|
|
regulation of cytokinesis
|
GO:0032465 |
45 |
0.109
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.107
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.106
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.105
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.105
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.103
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.101
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.101
|
Fly |
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.100
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.098
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.097
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.097
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.097
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.095
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.095
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.095
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.094
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.094
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.094
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.094
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.091
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.091
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.091
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.090
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.089
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.088
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.087
|
|
|
|
negative regulation of protein oligomerization
|
GO:0032460 |
8 |
0.087
|
|
|
|
system process
|
GO:0003008 |
349 |
0.086
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.086
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.086
|
Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.086
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.086
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.085
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.085
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.084
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.084
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.083
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.082
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.081
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.081
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.081
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.079
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.079
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.079
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.079
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.078
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.077
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.077
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.077
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.077
|
|
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.077
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.076
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.076
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.075
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.074
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.074
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.074
|
|
|
|
regulation of neuroblast proliferation
|
GO:1902692 |
3 |
0.072
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.072
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.072
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.071
|
|
|
|
synapse organization
|
GO:0050808 |
14 |
0.070
|
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.069
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.069
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.069
|
Fly |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.068
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.067
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.067
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.066
|
|
|
|
positive regulation of neuroblast proliferation
|
GO:0002052 |
2 |
0.066
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.066
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.065
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.065
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.065
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.063
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.063
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.062
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.062
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.062
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.061
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.061
|
|
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.061
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.061
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.061
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.059
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.058
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.058
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.058
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.057
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.056
|
|
|
|
regulation of apoptotic cell clearance
|
GO:2000425 |
5 |
0.056
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.056
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.055
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.055
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.055
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.054
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.054
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
42 |
0.054
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.054
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.053
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.053
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.052
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.052
|
Fly |
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.051
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.051
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.051
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
13 |
0.051
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
21 |
0.051
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
13 |
0.051
|
Fly |
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.051
|
|
|
|
positive regulation of cytokinesis
|
GO:0032467 |
29 |
0.050
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.050
|
Fly |
|
|
segmentation
|
GO:0035282 |
4 |
0.050
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.050
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.049
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.049
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.049
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.049
|
Fly |
|
|
phospholipid biosynthetic process
|
GO:0008654 |
44 |
0.049
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
26 |
0.049
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.048
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.048
|
|
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.048
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.048
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.047
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.047
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.047
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.047
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.047
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.046
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.046
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.046
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.046
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.046
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.046
|
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
13 |
0.046
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.046
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.045
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.045
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.045
|
|
|
|
carbohydrate transport
|
GO:0008643 |
37 |
0.045
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.044
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.044
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.044
|
|
|
|
regulation of axon regeneration
|
GO:0048679 |
1 |
0.044
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.043
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.043
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
17 |
0.043
|
Fly |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.042
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.042
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.042
|
|
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
0.042
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.041
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.041
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.041
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.041
|
|
|
|
regulation of response to interferon gamma
|
GO:0060330 |
7 |
0.041
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
25 |
0.040
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.040
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.040
|
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
10 |
0.039
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.039
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.039
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.039
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.038
|
|
|
|
cellular response to retinoic acid
|
GO:0071300 |
19 |
0.038
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.038
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.038
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.038
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.038
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.037
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
7 |
0.037
|
|
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
10 |
0.037
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.037
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.037
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.037
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.037
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.037
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.036
|
|
|
|
neuron migration
|
GO:0001764 |
11 |
0.036
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.036
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.036
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.035
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.035
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.034
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.034
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.034
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.034
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.034
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.034
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.034
|
|
|
|
regulation of podosome assembly
|
GO:0071801 |
5 |
0.034
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.033
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.033
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.033
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.032
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.032
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
1 |
0.032
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.032
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.031
|
Fly |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.031
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.031
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.031
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.031
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.031
|
|