IMP
Process View
erbb signaling pathway
A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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Click on a gene's description to view its network relationships with genes known to be involved in "erbb signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.999 | ||
| EGFR | epidermal growth factor receptor | 0.988 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.964 | Human | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.613 | Mouse Fly | |
| RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.609 | Fly | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.562 | Human | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.481 | Rat | |
| APP | amyloid beta (A4) precursor protein | 0.399 | Mouse | |
| GHR | growth hormone receptor | 0.303 | ||
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.302 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.299 | Fly | |
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.294 | Human | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.281 | Human Rat | |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.271 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.245 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.208 | Fly | |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.187 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.170 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.165 | Mouse | |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.139 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.137 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.136 | Mouse | |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.129 | ||
| DLG4 | discs, large homolog 4 (Drosophila) | 0.129 | Fly | |
| PXN | paxillin | 0.126 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.123 | Human | |
| DUSP1 | dual specificity phosphatase 1 | 0.122 | ||
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.108 | ||
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.107 | ||
| MUC1 | mucin 1, cell surface associated | 0.104 | ||
| STAMBP | STAM binding protein | 0.103 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.100 | ||
| SPRR2A | small proline-rich protein 2A | 0.099 | ||
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.096 | ||
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.096 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.093 | Fly | |
| UBE3A | ubiquitin protein ligase E3A | 0.092 | ||
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 | 0.092 | Fly | |
| ESR1 | estrogen receptor 1 | 0.091 | Rat | |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.090 | ||
| TSG101 | tumor susceptibility gene 101 | 0.089 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.088 | ||
| EZR | ezrin | 0.086 | ||
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.085 | ||
| ARHGAP1 | Rho GTPase activating protein 1 | 0.076 | ||
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.076 | ||
| GDA | guanine deaminase | 0.073 | ||
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.070 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.067 | ||
| ABI2 | abl-interactor 2 | 0.065 | ||
| DSG2 | desmoglein 2 | 0.064 | ||
| LAT | linker for activation of T cells | 0.062 | ||
| YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.060 | ||
| PRKCA | protein kinase C, alpha | 0.060 | ||
| ARHGAP5 | Rho GTPase activating protein 5 | 0.059 | ||
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.059 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.058 | ||
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.058 | ||
| PTEN | phosphatase and tensin homolog | 0.058 | ||
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.056 | Human | |
| IRS1 | insulin receptor substrate 1 | 0.054 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.054 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.053 | ||
| TFF1 | trefoil factor 1 | 0.052 | ||
| GRN | granulin | 0.052 | ||
| NCK1 | NCK adaptor protein 1 | 0.051 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.051 | ||
| NOTCH1 | notch 1 | 0.050 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.050 | Human Fly | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.050 | ||
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.048 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.046 | ||
| CD28 | CD28 molecule | 0.045 | ||
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.045 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.045 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.045 | ||
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | 0.044 | ||
| SH3GL3 | SH3-domain GRB2-like 3 | 0.043 | ||
| CAV2 | caveolin 2 | 0.043 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.043 | ||
| CSNK1G3 | casein kinase 1, gamma 3 | 0.042 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.041 | ||
| PBK | PDZ binding kinase | 0.041 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.039 | ||
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.039 | ||
| YAP1 | Yes-associated protein 1 | 0.039 | ||
| CLASP1 | cytoplasmic linker associated protein 1 | 0.038 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.038 | ||
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.038 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.037 | ||
| FBLN1 | fibulin 1 | 0.037 | Human | |
| EPOR | erythropoietin receptor | 0.036 | ||
| RIN1 | Ras and Rab interactor 1 | 0.035 | ||
| SH2D3A | SH2 domain containing 3A | 0.035 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.035 | Human | |
| PSAP | prosaposin | 0.034 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.034 | ||
| ATN1 | atrophin 1 | 0.034 | ||
| HDAC4 | histone deacetylase 4 | 0.034 | ||
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.034 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.033 | Mouse | |
| SH3GL2 | SH3-domain GRB2-like 2 | 0.033 | ||
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.032 | Mouse | |
| ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.032 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.032 | Human | |
| TGFA | transforming growth factor, alpha | 0.032 | ||
| MPDZ | multiple PDZ domain protein | 0.032 | ||
| ZNF746 | zinc finger protein 746 | 0.031 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.031 | ||
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.030 | ||
| JUP | junction plakoglobin | 0.030 | ||
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.029 | ||
| ADAM10 | ADAM metallopeptidase domain 10 | 0.029 | ||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.029 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.028 | Fly | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.028 | ||
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.028 | ||
| FYB | FYN binding protein | 0.028 | ||
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.027 | Fly | |
| SLK | STE20-like kinase | 0.027 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.027 | ||
| LOXL1 | lysyl oxidase-like 1 | 0.027 | ||
| RNF11 | ring finger protein 11 | 0.027 | ||
| SKIL | SKI-like oncogene | 0.027 | ||
| TRIP6 | thyroid hormone receptor interactor 6 | 0.026 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.026 | ||
| DUSP3 | dual specificity phosphatase 3 | 0.026 | ||
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.026 | ||
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.026 | Rat | |
| SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.026 | ||
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.025 | ||
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.025 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.025 | Human Fly | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.025 | ||
| PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.024 | ||
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.024 | Fly | |
| DOK4 | docking protein 4 | 0.024 | ||
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.024 | Fly | |
| HDAC6 | histone deacetylase 6 | 0.024 | ||
| JAG1 | jagged 1 | 0.024 | ||
| PBRM1 | polybromo 1 | 0.024 | ||
| CCDC6 | coiled-coil domain containing 6 | 0.024 | ||
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.024 | ||
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.024 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.023 | ||
| MED28 | mediator complex subunit 28 | 0.023 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.023 | Human | |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.023 | ||
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.023 | ||
| ATXN1L | ataxin 1-like | 0.023 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.023 | ||
| MATK | megakaryocyte-associated tyrosine kinase | 0.022 | ||
| SOCS5 | suppressor of cytokine signaling 5 | 0.022 | ||
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.022 | Fly | |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) | 0.022 | ||
| VPS24 | vacuolar protein sorting 24 homolog (S. cerevisiae) | 0.022 | ||
| TNS4 | tensin 4 | 0.022 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.022 | ||
| CHMP4B | chromatin modifying protein 4B | 0.022 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.022 | ||
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.022 | ||
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.021 | ||
| CISH | cytokine inducible SH2-containing protein | 0.021 | Human | |
| PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.021 | ||
| RALBP1 | ralA binding protein 1 | 0.021 | ||
| FN1 | fibronectin 1 | 0.021 | ||
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.021 | ||
| RIN2 | Ras and Rab interactor 2 | 0.021 | ||
| FNBP1L | formin binding protein 1-like | 0.021 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.020 | ||
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 | 0.020 | ||
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.020 | ||
| RSBN1 | round spermatid basic protein 1 | 0.020 | ||
| DAZAP2 | DAZ associated protein 2 | 0.020 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.020 | ||
| MAML1 | mastermind-like 1 (Drosophila) | 0.020 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.020 | Fly | |
| RHOXF2 | Rhox homeobox family, member 2 | 0.019 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.019 | ||
| SH3D19 | SH3 domain containing 19 | 0.019 | ||
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.019 | Fly | |
| UBQLN2 | ubiquilin 2 | 0.019 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.019 | ||
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.019 | Fly | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.019 | ||
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.019 | ||
| BMI1 | BMI1 polycomb ring finger oncogene | 0.019 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.019 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.019 | Human | |
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.019 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.019 | ||
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.019 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.019 | ||
| PRKCE | protein kinase C, epsilon | 0.018 | ||
| DPYSL4 | dihydropyrimidinase-like 4 | 0.018 | ||
| PRPF4B | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 0.018 | ||
| SMAD2 | SMAD family member 2 | 0.018 | ||
| NOTCH3 | notch 3 | 0.018 | ||
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.018 | ||
| MAPT | microtubule-associated protein tau | 0.018 | ||
| EEA1 | early endosome antigen 1 | 0.018 | ||
| ANXA1 | annexin A1 | 0.018 | ||
| REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 0.018 | ||
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.018 | ||
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 0.018 | ||
| FSTL1 | follistatin-like 1 | 0.018 | ||
| S100A4 | S100 calcium binding protein A4 | 0.017 | ||
| NUP54 | nucleoporin 54kDa | 0.017 | ||
| RYK | RYK receptor-like tyrosine kinase | 0.017 | ||
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.017 | Fly | |
| FLNB | filamin B, beta | 0.017 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.017 | ||
| EIF1B | eukaryotic translation initiation factor 1B | 0.017 | ||
| CD59 | CD59 molecule, complement regulatory protein | 0.017 | ||
| NACAD | NAC alpha domain containing | 0.017 | ||
| EGF | epidermal growth factor | 0.017 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.017 | ||
| MATR3 | matrin 3 | 0.017 | ||
| SEC24B | SEC24 family, member B (S. cerevisiae) | 0.017 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.017 | ||
| IRS4 | insulin receptor substrate 4 | 0.017 | ||
| BLK | B lymphoid tyrosine kinase | 0.016 | ||
| MAGOHB | mago-nashi homolog B (Drosophila) | 0.016 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.016 | ||
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.016 | ||
| ENG | endoglin | 0.016 | ||
| HCK | hemopoietic cell kinase | 0.016 | ||
| KSR1 | kinase suppressor of ras 1 | 0.016 | ||
| SIRT1 | sirtuin 1 | 0.016 | ||
| ADAM17 | ADAM metallopeptidase domain 17 | 0.016 | ||
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 0.016 | ||
| KCTD1 | potassium channel tetramerisation domain containing 1 | 0.016 | ||
| ZNF644 | zinc finger protein 644 | 0.016 | ||
| RHOA | ras homolog gene family, member A | 0.016 | Fly | |
| NXF1 | nuclear RNA export factor 1 | 0.016 | ||
| MAP2K2 | mitogen-activated protein kinase kinase 2 | 0.016 | ||
| PPP5C | protein phosphatase 5, catalytic subunit | 0.016 | ||
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.015 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.015 | ||
| PTK6 | PTK6 protein tyrosine kinase 6 | 0.015 | ||
| NUMB | numb homolog (Drosophila) | 0.015 | ||
| CD2AP | CD2-associated protein | 0.015 | ||
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.015 | ||
| ITGB4 | integrin, beta 4 | 0.015 | ||
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.015 | ||
| SOCS4 | suppressor of cytokine signaling 4 | 0.015 | ||
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.015 | ||
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.015 | ||
| SP3 | Sp3 transcription factor | 0.015 | ||
| ADNP | activity-dependent neuroprotector homeobox | 0.015 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.015 | ||
| RHEB | Ras homolog enriched in brain | 0.015 | ||
| TMEM173 | transmembrane protein 173 | 0.015 | ||
| BLNK | B-cell linker | 0.015 | ||
| MBP | myelin basic protein | 0.015 | ||
| CTGF | connective tissue growth factor | 0.015 | ||
| USP8 | ubiquitin specific peptidase 8 | 0.015 | ||
| THBS1 | thrombospondin 1 | 0.015 | ||
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.015 | ||
| MYLK2 | myosin light chain kinase 2 | 0.015 | ||
| DOK6 | docking protein 6 | 0.015 | ||
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.015 | ||
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.015 | ||
| AGRN | agrin | 0.015 | ||
| EIF2C3 | eukaryotic translation initiation factor 2C, 3 | 0.014 | ||
| DPPA4 | developmental pluripotency associated 4 | 0.014 | ||
| NUMBL | numb homolog (Drosophila)-like | 0.014 | ||
| EPHA2 | EPH receptor A2 | 0.014 | ||
| NCSTN | nicastrin | 0.014 | ||
| JAG2 | jagged 2 | 0.014 | ||
| CLNK | cytokine-dependent hematopoietic cell linker | 0.014 | ||
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.014 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.014 | ||
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.014 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.014 | ||
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.014 | ||
| AHNAK | AHNAK nucleoprotein | 0.014 | ||
| EXOC5 | exocyst complex component 5 | 0.014 | ||
| NCK2 | NCK adaptor protein 2 | 0.014 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.014 | ||
| XPO6 | exportin 6 | 0.014 | ||
| CUL2 | cullin 2 | 0.014 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.014 | ||
| RBM42 | RNA binding motif protein 42 | 0.014 | ||
| FEM1B | fem-1 homolog b (C. elegans) | 0.014 | ||
| GRAP2 | GRB2-related adaptor protein 2 | 0.013 | Fly | |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.013 | ||
| ARRDC3 | arrestin domain containing 3 | 0.013 | ||
| SBF1 | SET binding factor 1 | 0.013 | ||
| ZZZ3 | zinc finger, ZZ-type containing 3 | 0.013 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.013 | ||
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.013 | ||
| SNX33 | sorting nexin 33 | 0.013 | ||
| PLSCR4 | phospholipid scramblase 4 | 0.013 | ||
| TNS3 | tensin 3 | 0.013 | ||
| BTBD3 | BTB (POZ) domain containing 3 | 0.013 | ||
| ADORA2A | adenosine A2a receptor | 0.013 | ||
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.013 | ||
| RNF38 | ring finger protein 38 | 0.013 | ||
| MEGF6 | multiple EGF-like-domains 6 | 0.013 | ||
| CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.013 | ||
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.013 | ||
| SNX9 | sorting nexin 9 | 0.013 | ||
| CRY1 | cryptochrome 1 (photolyase-like) | 0.013 | ||
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.013 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.013 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.013 | Rat Fly | |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.013 | ||
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 | 0.013 | ||
| LAMB2 | laminin, beta 2 (laminin S) | 0.013 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.013 | ||
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.013 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.013 | ||
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | 0.012 | ||
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 0.012 | ||
| AGPS | alkylglycerone phosphate synthase | 0.012 | ||
| TSSC4 | tumor suppressing subtransferable candidate 4 | 0.012 | ||
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.012 | ||
| DSP | desmoplakin | 0.012 | ||
| AZIN1 | antizyme inhibitor 1 | 0.012 | ||
| CAPRIN2 | caprin family member 2 | 0.012 | ||
| DMPK | dystrophia myotonica-protein kinase | 0.012 | ||
| AXIN1 | axin 1 | 0.012 | ||
| KIF5B | kinesin family member 5B | 0.012 | ||
| ANKRD13C | ankyrin repeat domain 13C | 0.012 | ||
| PIK3C2A | phosphoinositide-3-kinase, class 2, alpha polypeptide | 0.012 | ||
| LMAN1 | lectin, mannose-binding, 1 | 0.012 | ||
| IPO11 | importin 11 | 0.012 | ||
| PECAM1 | platelet/endothelial cell adhesion molecule | 0.012 | ||
| POLD4 | polymerase (DNA-directed), delta 4 | 0.012 | ||
| SCRIB | scribbled homolog (Drosophila) | 0.012 | ||
| ZNF775 | zinc finger protein 775 | 0.012 | ||
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4 | 0.012 | Human | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.012 | ||
| CDCP1 | CUB domain containing protein 1 | 0.012 | ||
| SFN | stratifin | 0.012 | ||
| RNF111 | ring finger protein 111 | 0.012 | ||
| APOA1 | apolipoprotein A-I | 0.012 | ||
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.012 | ||
| JAK2 | Janus kinase 2 | 0.012 | ||
| IGSF21 | immunoglobin superfamily, member 21 | 0.012 | ||
| SOCS6 | suppressor of cytokine signaling 6 | 0.012 | Human Fly | |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.012 | ||
| NIPBL | Nipped-B homolog (Drosophila) | 0.012 | ||
| DOK5 | docking protein 5 | 0.012 | ||
| DOCK1 | dedicator of cytokinesis 1 | 0.012 | ||
| DEGS1 | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 0.012 | ||
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 0.012 | ||
| DAZ1 | deleted in azoospermia 1 | 0.012 | ||
| HSPG2 | heparan sulfate proteoglycan 2 | 0.012 | Worm | |
| PKP4 | plakophilin 4 | 0.012 | ||
| PRKCI | protein kinase C, iota | 0.012 | ||
| MEGF11 | multiple EGF-like-domains 11 | 0.012 | ||
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.012 | ||
| CHMP1A | chromatin modifying protein 1A | 0.012 | ||
| SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.012 | ||
| MAP1S | microtubule-associated protein 1S | 0.012 | ||
| ARHGAP12 | Rho GTPase activating protein 12 | 0.012 | ||
| LRR1 | leucine rich repeat protein 1 | 0.011 | ||
| SSR1 | signal sequence receptor, alpha | 0.011 | ||
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.011 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.011 | ||
| HK2 | hexokinase 2 | 0.011 | ||
| NET1 | neuroepithelial cell transforming 1 | 0.011 | ||
| LIN7C | lin-7 homolog C (C. elegans) | 0.011 | Worm | |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.011 | ||
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.011 | ||
| FZD7 | frizzled homolog 7 (Drosophila) | 0.011 | ||
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.011 | ||
| NID1 | nidogen 1 | 0.011 | ||
| KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.011 | Worm | |
| SCAF8 | SR-related CTD-associated factor 8 | 0.011 | ||
| JAK1 | Janus kinase 1 | 0.011 | ||
| CYTB | cytochrome b | 0.011 | ||
| VEZF1 | vascular endothelial zinc finger 1 | 0.011 | ||
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.011 | ||
| NSF | N-ethylmaleimide-sensitive factor | 0.011 | ||
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.011 | ||
| SRI | sorcin | 0.011 | ||
| SHPRH | SNF2 histone linker PHD RING helicase | 0.011 | ||
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.011 | ||
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.011 | ||
| SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.011 | ||
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.011 | ||
| PRNP | prion protein | 0.011 | ||
| TNRC6B | trinucleotide repeat containing 6B | 0.011 | ||
| ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.011 | ||
| BAG1 | BCL2-associated athanogene | 0.011 | ||
| OGFR | opioid growth factor receptor | 0.011 | ||
| EFS | embryonal Fyn-associated substrate | 0.011 | ||
| TBL1X | transducin (beta)-like 1X-linked | 0.011 | Fly | |
| NRG1 | neuregulin 1 | 0.011 | ||
| ADRM1 | adhesion regulating molecule 1 | 0.011 | ||
| CAMSAP1L1 | calmodulin regulated spectrin-associated protein 1-like 1 | 0.011 | ||
| USP17 | ubiquitin specific peptidase 17 | 0.011 | ||
| SASH3 | SAM and SH3 domain containing 3 | 0.011 | ||
| ELL | elongation factor RNA polymerase II | 0.011 | ||
| PKP3 | plakophilin 3 | 0.011 | ||
| NMD3 | NMD3 homolog (S. cerevisiae) | 0.011 | ||
| C1orf93 | chromosome 1 open reading frame 93 | 0.011 | ||
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.011 | ||
| CTSD | cathepsin D | 0.011 | ||
| LINGO1 | leucine rich repeat and Ig domain containing 1 | 0.011 | ||
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) | 0.011 | ||
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.011 | ||
| DLG2 | discs, large homolog 2 (Drosophila) | 0.011 | Fly | |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.011 | ||
| BMP2 | bone morphogenetic protein 2 | 0.011 | ||
| TNRC6A | trinucleotide repeat containing 6A | 0.011 | ||
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.011 | ||
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.011 | Fly | |
| CCNK | cyclin K | 0.011 | ||
| CTRC | chymotrypsin C (caldecrin) | 0.011 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.010 | ||
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.010 | ||
| GIGYF1 | GRB10 interacting GYF protein 1 | 0.010 | ||
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.010 | ||
| SSFA2 | sperm specific antigen 2 | 0.010 | ||
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.010 | ||
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.010 | ||
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.010 | Human | |
| COL5A1 | collagen, type V, alpha 1 | 0.010 | ||
| NOMO2 | NODAL modulator 2 | 0.010 | ||
| ZBTB6 | zinc finger and BTB domain containing 6 | 0.010 | ||
| EFCAB4B | EF-hand calcium binding domain 4B | 0.010 | ||
| BACE1 | beta-site APP-cleaving enzyme 1 | 0.010 | ||
| SGPL1 | sphingosine-1-phosphate lyase 1 | 0.010 | ||
| ZCCHC11 | zinc finger, CCHC domain containing 11 | 0.010 | ||
| GSN | gelsolin | 0.010 | Human | |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.010 | ||
| DEDD | death effector domain containing | 0.010 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.010 | ||
| PRKCD | protein kinase C, delta | 0.010 | ||
| PCNP | PEST proteolytic signal containing nuclear protein | 0.010 | ||
| MEGF8 | multiple EGF-like-domains 8 | 0.010 | ||
| CORO1C | coronin, actin binding protein, 1C | 0.010 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.010 | ||
| PSEN1 | presenilin 1 | 0.010 | Mouse |