Homo sapiens

55 known processes

NUP153

nucleoporin 153kDa

(Aliases: HNUP153,N153)

NUP153 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleus organization GO:0006997 28 0.952
single organism nuclear import GO:1902593 104 0.830
Fly
nucleocytoplasmic transport GO:0006913 176 0.799
intracellular protein transport GO:0006886 270 0.790
Human Fly
protein localization to nucleus GO:0034504 136 0.765
Fly
cytoplasmic transport GO:0016482 379 0.724
cellular amine metabolic process GO:0044106 41 0.708
nuclear pore complex assembly GO:0051292 7 0.682
protein targeting to nucleus GO:0044744 104 0.661
Fly
protein import into nucleus GO:0006606 104 0.653
Fly
nls bearing protein import into nucleus GO:0006607 2 0.583
Fly
amine metabolic process GO:0009308 44 0.538
female gamete generation GO:0007292 2 0.532
smad protein import into nucleus GO:0007184 13 0.500
Fly
post embryonic development GO:0009791 2 0.474
mitotic cell cycle GO:0000278 326 0.466
nucleobase containing compound transport GO:0015931 51 0.446
establishment of protein localization to organelle GO:0072594 172 0.446
Fly
protein targeting GO:0006605 187 0.422
Fly
protein import GO:0017038 130 0.378
Fly
cellular amino acid metabolic process GO:0006520 116 0.377
enzyme linked receptor protein signaling pathway GO:0007167 303 0.365
Fly
regulation of nucleocytoplasmic transport GO:0046822 98 0.357
tube development GO:0035295 125 0.342
regulation of cell cycle GO:0051726 393 0.330
nuclear transport GO:0051169 179 0.294
microtubule cytoskeleton organization GO:0000226 176 0.282
Fly
single organism cellular localization GO:1902580 332 0.275
Fly
regulation of mitotic cell cycle GO:0007346 189 0.271
protein localization to organelle GO:0033365 280 0.268
Fly
nuclear import GO:0051170 106 0.263
Fly
oocyte development GO:0048599 1 0.255
mitotic cell cycle process GO:1903047 286 0.245
rna transport GO:0050658 39 0.231
neural tube formation GO:0001841 3 0.230
nitrogen compound transport GO:0071705 191 0.201
nucleic acid transport GO:0050657 39 0.199
posttranscriptional regulation of gene expression GO:0010608 213 0.167
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.160
Fly
signal transduction by phosphorylation GO:0023014 297 0.160
organonitrogen compound biosynthetic process GO:1901566 200 0.158
regulation of cellular amine metabolic process GO:0033238 11 0.153
nucleosome organization GO:0034728 66 0.153
regulation of intracellular transport GO:0032386 195 0.144
nervous system development GO:0007399 293 0.143
Fly
protein modification by small protein removal GO:0070646 92 0.137
regulation of cellular ketone metabolic process GO:0010565 50 0.130
nuclear pore organization GO:0006999 10 0.129
histone exchange GO:0043486 3 0.126
negative regulation of cellular protein metabolic process GO:0032269 353 0.126
dna conformation change GO:0071103 113 0.125
cellular response to dna damage stimulus GO:0006974 379 0.121
regulation of cytoplasmic transport GO:1903649 149 0.119
embryonic morphogenesis GO:0048598 85 0.118
ribosomal protein import into nucleus GO:0006610 2 0.117
embryo development GO:0009790 123 0.111
Worm
neurogenesis GO:0022008 169 0.110
Fly
regulation of cell differentiation GO:0045595 393 0.104
morphogenesis of embryonic epithelium GO:0016331 4 0.103
mapk cascade GO:0000165 288 0.103
protein modification by small protein conjugation GO:0032446 342 0.101
cellular ketone metabolic process GO:0042180 80 0.100
oogenesis GO:0048477 2 0.099
chromatin modification GO:0016568 298 0.096
Fly
tube morphogenesis GO:0035239 95 0.095
spermatid development GO:0007286 4 0.093
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.093
embryonic epithelial tube formation GO:0001838 4 0.093
apoptotic signaling pathway GO:0097190 268 0.090
centrosome organization GO:0051297 58 0.090
Fly
vesicle mediated transport GO:0016192 371 0.088
microtubule based process GO:0007017 210 0.085
Fly
chromatin assembly or disassembly GO:0006333 78 0.083
dna packaging GO:0006323 77 0.082
chromatin organization GO:0006325 351 0.082
Fly
cell cycle phase transition GO:0044770 173 0.080
mrna transport GO:0051028 30 0.080
cell cycle checkpoint GO:0000075 117 0.079
regulation of cell cycle process GO:0010564 266 0.077
organophosphate biosynthetic process GO:0090407 163 0.077
chromatin assembly GO:0031497 61 0.077
peptidyl serine phosphorylation GO:0018105 101 0.077
cellular component morphogenesis GO:0032989 314 0.075
epithelium development GO:0060429 227 0.072
lipid metabolic process GO:0006629 381 0.070
positive regulation of cellular amine metabolic process GO:0033240 7 0.070
response to biotic stimulus GO:0009607 276 0.069
positive regulation of protein transport GO:0051222 135 0.069
nuclear export GO:0051168 69 0.068
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.068
positive regulation of developmental process GO:0051094 314 0.068
response to abiotic stimulus GO:0009628 336 0.066
negative regulation of cell cycle phase transition GO:1901988 89 0.066
negative regulation of protein metabolic process GO:0051248 391 0.063
regulation of cellular amino acid metabolic process GO:0006521 6 0.062
mrna metabolic process GO:0016071 175 0.061
regulation of protein targeting GO:1903533 91 0.061
regulation of cellular response to stress GO:0080135 244 0.060
organelle assembly GO:0070925 176 0.058
internal protein amino acid acetylation GO:0006475 101 0.058
chromatin remodeling GO:0006338 55 0.056
Fly
oocyte differentiation GO:0009994 2 0.054
establishment of rna localization GO:0051236 39 0.053
mrna processing GO:0006397 133 0.052
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.049
response to external biotic stimulus GO:0043207 261 0.049
embryo development ending in birth or egg hatching GO:0009792 34 0.049
Worm
regulation of protein localization to nucleus GO:1900180 85 0.048
negative regulation of cell death GO:0060548 345 0.048
reproductive process GO:0022414 106 0.047
peptidyl serine modification GO:0018209 106 0.047
single organism reproductive process GO:0044702 98 0.047
determination of adult lifespan GO:0008340 2 0.047
rna interference GO:0016246 4 0.046
defense response GO:0006952 315 0.046
multicellular organismal aging GO:0010259 3 0.046
regulation of cellular component biogenesis GO:0044087 281 0.045
negative regulation of phosphate metabolic process GO:0045936 267 0.045
cellular lipid metabolic process GO:0044255 303 0.045
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.045
response to other organism GO:0051707 261 0.044
maintenance of location GO:0051235 112 0.043
regulation of establishment of protein localization GO:0070201 242 0.043
negative regulation of catalytic activity GO:0043086 335 0.042
regulation of dna metabolic process GO:0051052 153 0.042
mitotic nuclear division GO:0007067 119 0.041
dna templated transcription initiation GO:0006352 35 0.040
organic hydroxy compound metabolic process GO:1901615 147 0.040
dna replication GO:0006260 116 0.040
phospholipid biosynthetic process GO:0008654 44 0.039
centrosome cycle GO:0007098 32 0.039
Fly
negative regulation of dna replication GO:0008156 29 0.039
cell morphogenesis GO:0000902 296 0.039
cellular macromolecular complex assembly GO:0034622 324 0.039
negative regulation of apoptotic process GO:0043066 316 0.039
negative regulation of transferase activity GO:0051348 124 0.039
neuroblast proliferation GO:0007405 4 0.039
protein ubiquitination GO:0016567 314 0.039
biological adhesion GO:0022610 331 0.038
rna export from nucleus GO:0006405 33 0.037
rna processing GO:0006396 255 0.037
rna localization GO:0006403 41 0.037
organelle fission GO:0048285 149 0.036
establishment of ribosome localization GO:0033753 4 0.036
modification dependent macromolecule catabolic process GO:0043632 212 0.036
response to nitrogen compound GO:1901698 184 0.036
response to oxygen containing compound GO:1901700 369 0.036
response to glucagon GO:0033762 1 0.036
regulation of cell division GO:0051302 116 0.036
regulation of protein import into nucleus GO:0042306 78 0.035
organelle localization GO:0051640 84 0.035
mrna export from nucleus GO:0006406 29 0.035
positive regulation of hydrolase activity GO:0051345 331 0.035
positive regulation of intracellular protein transport GO:0090316 76 0.034
segmentation GO:0035282 4 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
negative regulation of programmed cell death GO:0043069 321 0.034
regulation of mitotic cell cycle phase transition GO:1901990 118 0.034
regulation of cell shape GO:0008360 48 0.034
regulation of transferase activity GO:0051338 355 0.034
mrna splicing via spliceosome GO:0000398 89 0.033
negative regulation of protein modification process GO:0031400 200 0.033
intracellular receptor signaling pathway GO:0030522 104 0.033
carbohydrate metabolic process GO:0005975 207 0.032
regulation of protein maturation GO:1903317 150 0.032
intrinsic apoptotic signaling pathway GO:0097193 127 0.032
stem cell differentiation GO:0048863 93 0.031
positive regulation of transport GO:0051050 336 0.031
negative regulation of cell cycle GO:0045786 193 0.031
phospholipid metabolic process GO:0006644 99 0.030
glycerophospholipid metabolic process GO:0006650 84 0.030
positive regulation of immune response GO:0050778 159 0.030
cell division GO:0051301 168 0.030
nuclear division GO:0000280 128 0.030
positive regulation of organelle organization GO:0010638 195 0.029
protein processing GO:0016485 226 0.029
morphogenesis of an epithelium GO:0002009 60 0.029
positive regulation of protein import into nucleus GO:0042307 46 0.029
negative regulation of developmental process GO:0051093 247 0.028
response to hormone GO:0009725 175 0.028
ribonucleoprotein complex subunit organization GO:0071826 81 0.028
regulation of cysteine type endopeptidase activity GO:2000116 127 0.028
macromolecule methylation GO:0043414 97 0.027
regulation of protein processing GO:0070613 150 0.027
negative regulation of cell cycle process GO:0010948 121 0.027
regulation of apoptotic signaling pathway GO:2001233 175 0.027
negative regulation of protein maturation GO:1903318 142 0.027
small gtpase mediated signal transduction GO:0007264 78 0.027
protein maturation GO:0051604 233 0.027
regulation of anatomical structure morphogenesis GO:0022603 286 0.027
response to oxidative stress GO:0006979 121 0.026
negative regulation of cellular protein catabolic process GO:1903363 38 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
ribonucleoprotein complex export from nucleus GO:0071426 4 0.026
actin filament based process GO:0030029 224 0.026
extrinsic apoptotic signaling pathway GO:0097191 119 0.026
spermatid differentiation GO:0048515 4 0.025
positive regulation of cell differentiation GO:0045597 211 0.025
positive regulation of protein localization to nucleus GO:1900182 48 0.025
negative regulation of mitotic cell cycle GO:0045930 102 0.025
cell adhesion GO:0007155 325 0.025
multicellular organismal reproductive process GO:0048609 40 0.025
ribonucleoside monophosphate catabolic process GO:0009158 158 0.025
regulation of protein localization GO:0032880 296 0.024
regulation of mapk cascade GO:0043408 262 0.024
regulation of meiosis GO:0040020 3 0.024
single organism membrane organization GO:0044802 268 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of proteolysis GO:0030162 293 0.024
regulation of immune response GO:0050776 201 0.024
positive regulation of intracellular transport GO:0032388 104 0.024
regulation of mitosis GO:0007088 63 0.023
developmental process involved in reproduction GO:0003006 66 0.023
response to growth factor GO:0070848 205 0.023
regulation of cell morphogenesis GO:0022604 153 0.023
spindle elongation GO:0051231 4 0.023
phosphatidylcholine biosynthetic process GO:0006656 9 0.022
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.022
peptidyl threonine modification GO:0018210 45 0.022
regulation of cell cycle phase transition GO:1901987 126 0.022
protein catabolic process GO:0030163 325 0.022
negative regulation of multicellular organismal process GO:0051241 317 0.022
regulation of histone modification GO:0031056 47 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
peptidyl lysine acetylation GO:0018394 101 0.022
epithelial tube morphogenesis GO:0060562 38 0.022
positive regulation of phosphorylation GO:0042327 394 0.022
response to organonitrogen compound GO:0010243 156 0.022
glycerolipid metabolic process GO:0046486 107 0.022
regulation of intracellular protein transport GO:0033157 123 0.021
regulation of chromosome organization GO:0033044 103 0.021
translation GO:0006412 132 0.021
protein methylation GO:0006479 74 0.021
dna templated transcription termination GO:0006353 3 0.021
regulation of translation GO:0006417 89 0.021
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.021
cellular response to endogenous stimulus GO:0071495 336 0.021
regeneration GO:0031099 4 0.020
positive regulation of transferase activity GO:0051347 227 0.020
regulation of protein complex assembly GO:0043254 147 0.020
regulation of gene expression epigenetic GO:0040029 73 0.020
regulation of response to dna damage stimulus GO:2001020 94 0.020
blastoderm segmentation GO:0007350 2 0.020
negative regulation of cell differentiation GO:0045596 171 0.020
regulation of multi organism process GO:0043900 157 0.020
covalent chromatin modification GO:0016569 254 0.020
ribosome localization GO:0033750 4 0.020
regulation of protein ubiquitination GO:0031396 95 0.020
regulation of microtubule cytoskeleton organization GO:0070507 61 0.019
regulation of growth GO:0040008 165 0.019
regulation of dna templated transcription initiation GO:2000142 9 0.019
regulation of embryonic development GO:0045995 20 0.019
regulation of kinase activity GO:0043549 314 0.019
cell projection organization GO:0030030 252 0.019
regulation of protein kinase activity GO:0045859 289 0.019
system process GO:0003008 349 0.019
dna damage checkpoint GO:0000077 68 0.019
single organism carbohydrate metabolic process GO:0044723 193 0.019
phosphatidylcholine metabolic process GO:0046470 19 0.019
regulation of mrna metabolic process GO:1903311 53 0.019
reproduction GO:0000003 63 0.018
regulation of nuclear division GO:0051783 65 0.018
termination of rna polymerase ii transcription GO:0006369 1 0.018
positive regulation of defense response GO:0031349 87 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.018
mitotic spindle elongation GO:0000022 4 0.018
lipid localization GO:0010876 106 0.018
single organismal cell cell adhesion GO:0016337 148 0.018
peptidyl lysine modification GO:0018205 144 0.018
negative regulation of chromosome organization GO:2001251 48 0.018
regulation of glucokinase activity GO:0033131 2 0.018
cellular response to hormone stimulus GO:0032870 125 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
gene silencing GO:0016458 49 0.017
glycoprotein metabolic process GO:0009100 110 0.017
reproductive structure development GO:0048608 55 0.017
positive regulation of multi organism process GO:0043902 56 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.017
ribonucleoprotein complex localization GO:0071166 4 0.017
multi organism reproductive process GO:0044703 54 0.017
posttranscriptional gene silencing by rna GO:0035194 25 0.017
innate immune response GO:0045087 178 0.017
regulation of chromatin modification GO:1903308 51 0.017
ribonucleotide catabolic process GO:0009261 405 0.016
ethanolamine containing compound metabolic process GO:0042439 26 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.016
regulation of cell development GO:0060284 161 0.016
posttranscriptional gene silencing GO:0016441 25 0.016
cellular modified amino acid metabolic process GO:0006575 64 0.016
cell projection morphogenesis GO:0048858 129 0.016
regulation of innate immune response GO:0045088 97 0.016
protein desumoylation GO:0016926 4 0.016
cell development GO:0048468 328 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.016
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.016
regulation of locomotion GO:0040012 329 0.015
purine ribonucleoside metabolic process GO:0046128 437 0.015
regulation of defense response GO:0031347 154 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.015
endocytosis GO:0006897 159 0.015
long term memory GO:0007616 2 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
positive regulation of cell development GO:0010720 92 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
rna 3 end processing GO:0031123 35 0.015
microtubule organizing center organization GO:0031023 62 0.015
Fly
cellular response to oxygen containing compound GO:1901701 276 0.015
positive regulation of mitosis GO:0045840 25 0.015
proteasomal protein catabolic process GO:0010498 176 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.015
negative regulation of apoptotic signaling pathway GO:2001234 97 0.015
muscle structure development GO:0061061 98 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
cell activation GO:0001775 213 0.015
positive regulation of protein phosphorylation GO:0001934 313 0.015
modification dependent protein catabolic process GO:0019941 209 0.014
regulation of map kinase activity GO:0043405 108 0.014
regulation of peptidase activity GO:0052547 180 0.014
immune response GO:0006955 307 0.014
negative regulation of dna metabolic process GO:0051053 57 0.014
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.014
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.014
compound eye development GO:0048749 1 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
actin cytoskeleton organization GO:0030036 207 0.014
regulation of membrane potential GO:0042391 95 0.014
blood vessel morphogenesis GO:0048514 162 0.014
behavior GO:0007610 112 0.014
positive regulation of innate immune response GO:0045089 79 0.014
carbohydrate derivative biosynthetic process GO:1901137 207 0.014
positive regulation of cell death GO:0010942 263 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
cellular biogenic amine metabolic process GO:0006576 34 0.014
tissue morphogenesis GO:0048729 96 0.014
carbohydrate biosynthetic process GO:0016051 42 0.014
negative regulation of protein processing GO:0010955 142 0.014
neuron development GO:0048666 113 0.014
locomotory behavior GO:0007626 1 0.013
methylation GO:0032259 106 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
dna templated transcription elongation GO:0006354 25 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
sexual reproduction GO:0019953 37 0.013
negative regulation of organelle organization GO:0010639 126 0.013
multicellular organism reproduction GO:0032504 42 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
ribonucleoside triphosphate catabolic process GO:0009203 391 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
chordate embryonic development GO:0043009 34 0.013
ras protein signal transduction GO:0007265 73 0.013
lymphocyte activation GO:0046649 133 0.013
neuromuscular junction development GO:0007528 3 0.013
positive regulation of nfat protein import into nucleus GO:0051533 3 0.013
regulation of protein stability GO:0031647 87 0.013
positive regulation of programmed cell death GO:0043068 249 0.012
nucleosome positioning GO:0016584 3 0.012
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.012
negative regulation of proteolysis GO:0045861 132 0.012
vasculature development GO:0001944 181 0.012
neural tube development GO:0021915 9 0.012
blastocyst development GO:0001824 3 0.012
mitotic cell cycle checkpoint GO:0007093 68 0.012
response to bacterium GO:0009617 144 0.012
regulation of glucocorticoid secretion GO:2000849 4 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.012
positive regulation of immune system process GO:0002684 283 0.012
neurological system process GO:0050877 163 0.012
positive regulation of mapk cascade GO:0043410 190 0.012
rna splicing via transesterification reactions GO:0000375 90 0.012
reproductive system development GO:0061458 56 0.012
positive regulation of cellular catabolic process GO:0031331 284 0.012
phagocytosis GO:0006909 42 0.012
regulation of rna splicing GO:0043484 62 0.012
protein localization to chromosome GO:0034502 30 0.011
myosin filament organization GO:0031033 2 0.011
regulation of mrna processing GO:0050684 48 0.011
response to cytokine GO:0034097 232 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
cellular protein complex assembly GO:0043623 188 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
regulation of rna stability GO:0043487 23 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
primary neural tube formation GO:0014020 3 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.011
negative regulation of kinase activity GO:0033673 106 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of response to wounding GO:1903034 101 0.011
response to fungus GO:0009620 4 0.011
cellular response to decreased oxygen levels GO:0036294 51 0.011
defense response to other organism GO:0098542 129 0.011
dna integrity checkpoint GO:0031570 71 0.011
generation of neurons GO:0048699 152 0.011
neuron death GO:0070997 65 0.011
protein dna complex subunit organization GO:0071824 80 0.011
defense response to bacterium GO:0042742 63 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
rna splicing GO:0008380 131 0.010
axoneme assembly GO:0035082 3 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
nucleoside monophosphate catabolic process GO:0009125 159 0.010
associative learning GO:0008306 1 0.010
establishment of organelle localization GO:0051656 59 0.010
regulation of chromatin organization GO:1902275 56 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.010

NUP153 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.043
Human
cancer DOID:162 167 0.026
Human
organ system cancer DOID:0050686 164 0.026
Human
central nervous system disease DOID:331 186 0.021
neurodegenerative disease DOID:1289 102 0.021
nervous system disease DOID:863 431 0.021