Homo sapiens

125 known processes

OAS1

2',5'-oligoadenylate synthetase 1, 40/46kDa

(Aliases: OIAS,OIASI,IFI-4)

OAS1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral process GO:0048525 66 0.999
viral life cycle GO:0019058 132 0.999
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.997
multi organism cellular process GO:0044764 156 0.994
negative regulation of viral genome replication GO:0045071 35 0.994
regulation of viral genome replication GO:0045069 48 0.986
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.983
interspecies interaction between organisms GO:0044419 156 0.983
viral genome replication GO:0019079 50 0.978
negative regulation of multi organism process GO:0043901 92 0.967
response to biotic stimulus GO:0009607 276 0.965
viral process GO:0016032 146 0.940
defense response to virus GO:0051607 71 0.925
response to other organism GO:0051707 261 0.917
regulation of multi organism process GO:0043900 157 0.915
defense response GO:0006952 315 0.908
regulation of viral process GO:0050792 103 0.895
immune response GO:0006955 307 0.883
defense response to other organism GO:0098542 129 0.836
innate immune response GO:0045087 178 0.832
response to external biotic stimulus GO:0043207 261 0.820
protein myristoylation GO:0018377 1 0.782
Human
response to virus GO:0009615 126 0.765
immune effector process GO:0002252 159 0.737
positive regulation of rig i signaling pathway GO:1900246 4 0.693
regulation of nuclease activity GO:0032069 11 0.666
protein oligomerization GO:0051259 173 0.596
response to interferon alpha GO:0035455 11 0.564
nucleoside phosphate biosynthetic process GO:1901293 109 0.544
regulation of defense response GO:0031347 154 0.517
positive regulation of cell death GO:0010942 263 0.511
regulation of intracellular transport of viral material GO:1901252 2 0.487
macromolecule glycosylation GO:0043413 63 0.478
Human
immune response activating signal transduction GO:0002757 90 0.473
purine nucleotide biosynthetic process GO:0006164 84 0.420
glycoprotein metabolic process GO:0009100 110 0.416
Human
regulation of defense response to virus GO:0050688 33 0.415
regulation of intracellular transport GO:0032386 195 0.406
response to cytokine GO:0034097 232 0.387
regulation of cytokine production GO:0001817 232 0.361
glycosylation GO:0070085 71 0.348
Human
positive regulation of interferon beta production GO:0032728 17 0.331
regulation of apoptotic signaling pathway GO:2001233 175 0.327
innate immune response activating signal transduction GO:0002758 48 0.322
positive regulation of interferon alpha production GO:0032727 11 0.305
negative regulation of protein maturation GO:1903318 142 0.304
regulation of innate immune response GO:0045088 97 0.301
protein glycosylation GO:0006486 62 0.289
Human
pattern recognition receptor signaling pathway GO:0002221 48 0.282
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.282
carbohydrate derivative biosynthetic process GO:1901137 207 0.261
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.254
cytokine production GO:0001816 247 0.234
nuclear transport GO:0051169 179 0.233
response to dsrna GO:0043331 25 0.217
organonitrogen compound biosynthetic process GO:1901566 200 0.209
negative regulation of catalytic activity GO:0043086 335 0.198
negative regulation of protein metabolic process GO:0051248 391 0.195
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.192
cytoplasmic transport GO:0016482 379 0.177
positive regulation of multi organism process GO:0043902 56 0.173
lipoprotein metabolic process GO:0042157 42 0.172
Human
intracellular protein transport GO:0006886 270 0.166
positive regulation of innate immune response GO:0045089 79 0.162
multi organism intracellular transport GO:1902583 14 0.159
single organism carbohydrate metabolic process GO:0044723 193 0.154
nucleotide biosynthetic process GO:0009165 109 0.151
positive regulation of cytokine production GO:0001819 167 0.149
lipoprotein biosynthetic process GO:0042158 33 0.146
Human
negative regulation of mitochondrial depolarization GO:0051902 2 0.143
glycoprotein biosynthetic process GO:0009101 91 0.141
Human
regulation of immune effector process GO:0002697 91 0.139
viral transcription GO:0019083 35 0.139
organophosphate biosynthetic process GO:0090407 163 0.135
chemical homeostasis GO:0048878 306 0.132
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.132
regulation of cytoplasmic transport GO:1903649 149 0.128
negative regulation of multicellular organismal process GO:0051241 317 0.126
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.121
positive regulation of intracellular transport GO:0032388 104 0.120
transport of virus GO:0046794 14 0.117
protein acylation GO:0043543 138 0.114
Human
positive regulation of programmed cell death GO:0043068 249 0.108
multi organism metabolic process GO:0044033 41 0.108
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.103
protein maturation GO:0051604 233 0.102
viral gene expression GO:0019080 35 0.101
positive regulation of defense response GO:0031349 87 0.099
regulation of proteolysis GO:0030162 293 0.095
negative regulation of programmed cell death GO:0043069 321 0.094
positive regulation of type i interferon production GO:0032481 20 0.091
regulation of establishment of protein localization GO:0070201 242 0.087
negative regulation of transport GO:0051051 176 0.087
positive regulation of immune effector process GO:0002699 40 0.084
negative regulation of cellular protein metabolic process GO:0032269 353 0.080
rig i signaling pathway GO:0039529 7 0.078
negative regulation of hydrolase activity GO:0051346 182 0.078
regulation of nucleocytoplasmic transport GO:0046822 98 0.075
protein modification by small protein conjugation GO:0032446 342 0.073
protein polyubiquitination GO:0000209 110 0.072
regulation of protein maturation GO:1903317 150 0.072
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.072
positive regulation of proteolysis GO:0045862 142 0.069
negative regulation of proteolysis GO:0045861 132 0.069
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.067
positive regulation of apoptotic process GO:0043065 246 0.066
nucleocytoplasmic transport GO:0006913 176 0.065
apoptotic mitochondrial changes GO:0008637 57 0.065
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.065
apoptotic signaling pathway GO:0097190 268 0.064
regulation of rig i signaling pathway GO:0039535 6 0.063
protein ubiquitination GO:0016567 314 0.061
negative regulation of peptidase activity GO:0010466 91 0.061
regulation of protein processing GO:0070613 150 0.060
positive regulation of transport GO:0051050 336 0.060
activation of innate immune response GO:0002218 55 0.059
cellular macromolecule catabolic process GO:0044265 380 0.058
carbohydrate homeostasis GO:0033500 31 0.057
intracellular transport of virus GO:0075733 14 0.057
posttranscriptional regulation of gene expression GO:0010608 213 0.056
negative regulation of locomotion GO:0040013 118 0.055
response to lipid GO:0033993 206 0.054
regulation of peptidase activity GO:0052547 180 0.054
regulation of endopeptidase activity GO:0052548 170 0.053
negative regulation of secretion GO:0051048 58 0.052
release of cytochrome c from mitochondria GO:0001836 35 0.049
regulation of protein transport GO:0051223 213 0.048
activation of cysteine type endopeptidase activity GO:0097202 57 0.046
protein targeting GO:0006605 187 0.046
regulation of response to biotic stimulus GO:0002831 55 0.044
response to nitrogen compound GO:1901698 184 0.043
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.042
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.041
protein processing GO:0016485 226 0.040
positive regulation of intracellular protein transport GO:0090316 76 0.040
regulation of immune response GO:0050776 201 0.039
cell fate determination GO:0001709 3 0.039
cellular protein catabolic process GO:0044257 261 0.038
regulation of cell migration GO:0030334 289 0.037
regulation of transferase activity GO:0051338 355 0.037
single organism cellular localization GO:1902580 332 0.036
metal ion transport GO:0030001 272 0.035
glucose homeostasis GO:0042593 31 0.035
cellular response to interferon alpha GO:0035457 4 0.035
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.034
intracellular receptor signaling pathway GO:0030522 104 0.034
regulation of cellular component biogenesis GO:0044087 281 0.034
negative regulation of endopeptidase activity GO:0010951 84 0.034
transmembrane transport GO:0055085 399 0.034
negative regulation of protein processing GO:0010955 142 0.034
cellular response to cytokine stimulus GO:0071345 181 0.033
cellular response to external stimulus GO:0071496 111 0.033
hexose metabolic process GO:0019318 55 0.033
protein localization to organelle GO:0033365 280 0.032
positive regulation of viral entry into host cell GO:0046598 3 0.031
cellular macromolecular complex assembly GO:0034622 324 0.031
cell cycle arrest GO:0007050 71 0.031
negative regulation of apoptotic process GO:0043066 316 0.031
protein import into nucleus GO:0006606 104 0.031
regulation of protein localization GO:0032880 296 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.029
response to organic cyclic compound GO:0014070 204 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
regulation of angiogenesis GO:0045765 92 0.029
positive regulation of immune response GO:0050778 159 0.029
regulation of anatomical structure morphogenesis GO:0022603 286 0.029
carbohydrate metabolic process GO:0005975 207 0.029
cellular response to organic cyclic compound GO:0071407 127 0.028
regulation of kinase activity GO:0043549 314 0.028
organophosphate catabolic process GO:0046434 430 0.028
rna interference GO:0016246 4 0.027
negative regulation of cell proliferation GO:0008285 228 0.027
regulation of cell motility GO:2000145 299 0.027
positive regulation of immune system process GO:0002684 283 0.026
negative regulation of viral transcription GO:0032897 23 0.026
regulation of transmembrane transport GO:0034762 139 0.026
regulation of dna metabolic process GO:0051052 153 0.026
rna catabolic process GO:0006401 71 0.026
mitochondrion organization GO:0007005 156 0.025
positive regulation of endopeptidase activity GO:0010950 84 0.025
multi organism transport GO:0044766 14 0.025
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.025
response to exogenous dsrna GO:0043330 10 0.024
response to oxygen containing compound GO:1901700 369 0.024
cellular response to lipid GO:0071396 127 0.024
regulation of binding GO:0051098 111 0.024
glucose metabolic process GO:0006006 45 0.023
regulation of viral transcription GO:0046782 34 0.023
positive regulation of apoptotic signaling pathway GO:2001235 70 0.023
vesicle mediated transport GO:0016192 371 0.023
positive regulation of response to external stimulus GO:0032103 88 0.023
regulation of protein localization to nucleus GO:1900180 85 0.023
response to bacterium GO:0009617 144 0.023
extrinsic apoptotic signaling pathway GO:0097191 119 0.022
regulation of cytoskeleton organization GO:0051493 177 0.022
multi organism localization GO:1902579 14 0.022
regulation of dna binding GO:0051101 37 0.022
cellular response to oxygen containing compound GO:1901701 276 0.022
response to interferon gamma GO:0034341 39 0.022
regulation of cysteine type endopeptidase activity GO:2000116 127 0.021
positive regulation of cytoplasmic transport GO:1903651 82 0.021
regulation of ion transport GO:0043269 189 0.021
negative regulation of protein modification process GO:0031400 200 0.021
regulation of protein complex assembly GO:0043254 147 0.021
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.021
protein catabolic process GO:0030163 325 0.021
negative regulation of cell death GO:0060548 345 0.021
chromatin organization GO:0006325 351 0.021
immune response regulating signaling pathway GO:0002764 97 0.021
regulation of interleukin 4 biosynthetic process GO:0045402 2 0.020
type i interferon biosynthetic process GO:0045351 4 0.020
dna conformation change GO:0071103 113 0.020
determination of adult lifespan GO:0008340 2 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
regulation of secretion by cell GO:1903530 177 0.020
regulation of protein stability GO:0031647 87 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.019
regulation of actin filament based process GO:0032970 141 0.019
cellular response to molecule of bacterial origin GO:0071219 62 0.019
positive regulation of peptidase activity GO:0010952 88 0.019
response to lipopolysaccharide GO:0032496 70 0.019
regulation of membrane potential GO:0042391 95 0.019
protein import GO:0017038 130 0.019
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.019
membrane organization GO:0061024 292 0.019
cytidine deamination GO:0009972 7 0.018
secretion GO:0046903 254 0.018
negative regulation of defense response to virus by host GO:0050689 4 0.018
positive regulation of cellular component biogenesis GO:0044089 158 0.018
regulation of protein ubiquitination GO:0031396 95 0.018
zymogen activation GO:0031638 70 0.018
mapk cascade GO:0000165 288 0.018
protein k11 linked ubiquitination GO:0070979 24 0.018
regulation of protein export from nucleus GO:0046825 15 0.018
regulation of mapk cascade GO:0043408 262 0.018
interleukin 2 secretion GO:0070970 3 0.018
negative regulation of cell cycle GO:0045786 193 0.017
protein deubiquitination GO:0016579 79 0.017
negative regulation of secretion by cell GO:1903531 52 0.017
ion homeostasis GO:0050801 230 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.017
regulation of defense response to virus by host GO:0050691 22 0.017
production of molecular mediator of immune response GO:0002440 37 0.016
immune system development GO:0002520 195 0.016
negative regulation of intracellular transport GO:0032387 60 0.016
negative regulation of intracellular protein transport GO:0090317 42 0.016
negative regulation of phosphorylation GO:0042326 174 0.016
response to molecule of bacterial origin GO:0002237 82 0.016
double strand break repair GO:0006302 101 0.016
regulation of gene expression epigenetic GO:0040029 73 0.016
regulation of interferon beta production GO:0032648 22 0.015
positive regulation of organelle organization GO:0010638 195 0.015
protein export from nucleus GO:0006611 29 0.015
negative regulation of cell motility GO:2000146 104 0.015
regulation of intracellular protein transport GO:0033157 123 0.015
negative regulation of transferase activity GO:0051348 124 0.015
actin nucleation GO:0045010 21 0.015
positive regulation of protein complex assembly GO:0031334 86 0.015
negative regulation of ion transport GO:0043271 39 0.015
cytokine mediated signaling pathway GO:0019221 109 0.015
positive regulation of cellular component organization GO:0051130 376 0.015
protein lipidation GO:0006497 33 0.015
Human
regulation of response to external stimulus GO:0032101 222 0.015
regulation of ion homeostasis GO:2000021 73 0.015
regulation of cell cycle GO:0051726 393 0.015
positive regulation of toll like receptor signaling pathway GO:0034123 10 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
positive regulation of transferase activity GO:0051347 227 0.014
negative regulation of developmental process GO:0051093 247 0.014
negative regulation of kinase activity GO:0033673 106 0.014
ion transmembrane transport GO:0034220 338 0.014
positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling GO:0071848 2 0.014
negative regulation of protein transport GO:0051224 75 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
regulation of ion transmembrane transport GO:0034765 132 0.014
modification dependent macromolecule catabolic process GO:0043632 212 0.014
regulation of growth GO:0040008 165 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
anatomical structure homeostasis GO:0060249 100 0.014
regulation of vasculature development GO:1901342 97 0.014
fas signaling pathway GO:0036337 3 0.013
single organism membrane organization GO:0044802 268 0.013
regulation of metal ion transport GO:0010959 120 0.013
regulation of homeostatic process GO:0032844 121 0.013
myeloid cell differentiation GO:0030099 117 0.013
protein secretion GO:0009306 98 0.013
protein autoubiquitination GO:0051865 37 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
single organism nuclear import GO:1902593 104 0.013
signal transduction by p53 class mediator GO:0072331 72 0.013
spermatid differentiation GO:0048515 4 0.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.013
regulation of protein secretion GO:0050708 86 0.013
regulation of mitochondrial membrane potential GO:0051881 23 0.013
protein localization to nucleus GO:0034504 136 0.012
vasculature development GO:0001944 181 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
negative regulation of intracellular transport of viral material GO:1901253 2 0.012
purine ribonucleotide catabolic process GO:0009154 404 0.012
activation of immune response GO:0002253 114 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
regulation of protein catabolic process GO:0042176 155 0.012
positive regulation of protein import into nucleus GO:0042307 46 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.012
regulation of adaptive immune response GO:0002819 33 0.012
mrna metabolic process GO:0016071 175 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
interferon gamma production GO:0032609 39 0.012
dna repair GO:0006281 198 0.012
negative regulation of synaptic transmission GO:0050805 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 158 0.012
regulation of type i interferon production GO:0032479 26 0.011
response to type i interferon GO:0034340 14 0.011
cardiovascular system development GO:0072358 262 0.011
hematopoietic or lymphoid organ development GO:0048534 186 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
regulation of protein deubiquitination GO:0090085 4 0.011
negative regulation of catabolic process GO:0009895 104 0.011
adaptive immune response GO:0002250 49 0.011
cellular response to abiotic stimulus GO:0071214 117 0.011
negative regulation of protein ubiquitination GO:0031397 35 0.011
secretion by cell GO:0032940 226 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
divalent inorganic cation transport GO:0072511 158 0.011
negative regulation of epithelial cell migration GO:0010633 38 0.011
regulation of t helper 2 cell cytokine production GO:2000551 2 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.011
calcium ion import GO:0070509 23 0.010
purine ribonucleoside catabolic process GO:0046130 398 0.010
tissue migration GO:0090130 119 0.010
protein localization to membrane GO:0072657 160 0.010
circulatory system development GO:0072359 262 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
interferon alpha production GO:0032607 11 0.010
response to abiotic stimulus GO:0009628 336 0.010
purine containing compound catabolic process GO:0072523 411 0.010
actin filament based process GO:0030029 224 0.010
cellular protein complex assembly GO:0043623 188 0.010
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.010
response to radiation GO:0009314 151 0.010

OAS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 40 0.020
disease of metabolism DOID:0014667 295 0.002
carbohydrate metabolism disease DOID:0050013 32 0.002
acquired metabolic disease DOID:0060158 58 0.002
diabetes mellitus DOID:9351 31 0.001
glucose metabolism disease DOID:4194 32 0.001
type 1 diabetes mellitus DOID:9744 4 0.000