Homo sapiens

227 known processes

PKD1

polycystic kidney disease 1 (autosomal dominant)

(Aliases: Pc-1,PBP,TRPP1)

PKD1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spinal cord development GO:0021510 4 0.955
metanephric collecting duct development GO:0072205 2 0.882
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.845
metanephric tubule development GO:0072170 3 0.836
metanephric nephron epithelium development GO:0072243 4 0.816
detection of mechanical stimulus GO:0050982 4 0.790
Mouse
mating GO:0007618 1 0.787
metanephric distal tubule development GO:0072235 2 0.771
distal tubule development GO:0072017 4 0.765
sodium ion transport GO:0006814 61 0.745
regulation of muscle contraction GO:0006937 45 0.716
regulation of camp metabolic process GO:0030814 52 0.709
striated muscle contraction GO:0006941 52 0.706
calcium ion transmembrane transport GO:0070588 76 0.674
Human Mouse
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.659
metanephric nephron tubule development GO:0072234 3 0.629
regulation of purine nucleotide metabolic process GO:1900542 264 0.624
regulation of transmembrane transporter activity GO:0022898 74 0.610
sodium ion transmembrane transport GO:0035725 59 0.609
cyclic nucleotide metabolic process GO:0009187 82 0.577
metanephric nephron morphogenesis GO:0072273 7 0.573
s shaped body morphogenesis GO:0072050 4 0.571
muscle contraction GO:0006936 73 0.526
blood circulation GO:0008015 113 0.520
inorganic ion transmembrane transport GO:0098660 231 0.508
Human Mouse
metanephric loop of henle development GO:0072236 2 0.508
sequestering of metal ion GO:0051238 24 0.506
regulation of ion transmembrane transport GO:0034765 132 0.501
mesonephric epithelium development GO:0072163 14 0.464
regulation of ion transmembrane transporter activity GO:0032412 72 0.442
muscle system process GO:0003012 81 0.433
camp metabolic process GO:0046058 61 0.428
regulation of metal ion transport GO:0010959 120 0.426
regulation of nucleotide metabolic process GO:0006140 269 0.413
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.412
response to water GO:0009415 2 0.411
metal ion transport GO:0030001 272 0.408
Human Mouse
cardiac muscle contraction GO:0060048 34 0.402
nephron tubule morphogenesis GO:0072078 13 0.402
kidney morphogenesis GO:0060993 19 0.389
circulatory system process GO:0003013 113 0.389
renal tubule development GO:0061326 19 0.371
metanephric s shaped body morphogenesis GO:0072284 4 0.370
divalent metal ion transport GO:0070838 152 0.364
Human Mouse
positive regulation of protein phosphorylation GO:0001934 313 0.352
cellular response to water stimulus GO:0071462 1 0.346
mesonephros development GO:0001823 17 0.337
intracellular protein transport GO:0006886 270 0.332
Mouse
cellular potassium ion transport GO:0071804 60 0.330
nephron morphogenesis GO:0072028 15 0.326
embryonic placenta development GO:0001892 1 0.325
Mouse
monovalent inorganic cation transport GO:0015672 128 0.321
metanephric nephron development GO:0072210 9 0.317
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.317
heart process GO:0003015 62 0.311
nephron epithelium morphogenesis GO:0072088 15 0.310
reactive nitrogen species metabolic process GO:2001057 3 0.309
heart contraction GO:0060047 62 0.309
collecting duct development GO:0072044 2 0.299
nervous system development GO:0007399 293 0.298
positive regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031659 8 0.298
regulation of transferase activity GO:0051338 355 0.291
regulation of cardiac muscle contraction GO:0055117 33 0.281
reactive oxygen species metabolic process GO:0072593 75 0.280
regulation of muscle system process GO:0090257 53 0.279
positive regulation of phosphorylation GO:0042327 394 0.279
cell cycle arrest GO:0007050 71 0.273
Mouse
regulation of calcium ion transmembrane transport GO:1903169 28 0.261
calcium ion import GO:0070509 23 0.257
regulation of cell cycle arrest GO:0071156 36 0.253
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.241
mitotic cell cycle GO:0000278 326 0.240
regulation of transmembrane transport GO:0034762 139 0.235
cation transmembrane transport GO:0098655 238 0.235
Human Mouse
mesonephric tubule development GO:0072164 14 0.231
regulation of calcium ion transport GO:0051924 79 0.228
calcium mediated signaling GO:0019722 44 0.223
positive regulation of cell cycle arrest GO:0071158 23 0.221
regulation of cell cycle GO:0051726 393 0.221
regulation of kinase activity GO:0043549 314 0.219
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.219
positive regulation of ion transport GO:0043270 87 0.214
cellular response to oxygen containing compound GO:1901701 276 0.213
single organism cellular localization GO:1902580 332 0.210
Mouse
urogenital system development GO:0001655 65 0.210
cation transport GO:0006812 331 0.208
Human Mouse
cell development GO:0048468 328 0.200
regulation of ion transport GO:0043269 189 0.198
regulation of cell cycle process GO:0010564 266 0.198
Mouse
positive regulation of cell cycle process GO:0090068 106 0.196
cellular ion homeostasis GO:0006873 168 0.192
Rat
cellular response to fluid shear stress GO:0071498 7 0.187
cytoplasmic sequestering of protein GO:0051220 12 0.187
Mouse
nephron epithelium development GO:0072009 23 0.180
protein localization to organelle GO:0033365 280 0.178
Mouse
regulation of protein targeting GO:1903533 91 0.177
Mouse
collagen metabolic process GO:0032963 28 0.177
system process GO:0003008 349 0.177
positive regulation of cell cycle GO:0045787 140 0.176
regulation of heart contraction GO:0008016 50 0.176
transmembrane transport GO:0055085 399 0.174
Human Mouse
second messenger mediated signaling GO:0019932 78 0.171
cellular cation homeostasis GO:0030003 163 0.171
Rat
regulation of mitotic cell cycle GO:0007346 189 0.168
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.167
detection of stimulus GO:0051606 85 0.165
Mouse
divalent inorganic cation transport GO:0072511 158 0.164
Human Mouse
cell projection organization GO:0030030 252 0.164
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.162
regulation of reactive oxygen species metabolic process GO:2000377 41 0.162
regulation of protein import into nucleus GO:0042306 78 0.161
Mouse
protein import GO:0017038 130 0.157
Mouse
positive regulation of transferase activity GO:0051347 227 0.156
sequestering of calcium ion GO:0051208 17 0.156
positive regulation of transport GO:0051050 336 0.155
establishment of protein localization to organelle GO:0072594 172 0.153
Mouse
protein localization to nucleus GO:0034504 136 0.153
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 118 0.152
potassium ion transmembrane transport GO:0071805 60 0.151
cellular calcium ion homeostasis GO:0006874 117 0.151
Rat
negative regulation of protein transport GO:0051224 75 0.147
Mouse
nuclear transport GO:0051169 179 0.142
Mouse
potassium ion transport GO:0006813 62 0.141
cell adhesion GO:0007155 325 0.141
Mouse
reactive oxygen species biosynthetic process GO:1903409 4 0.139
neuron differentiation GO:0030182 138 0.137
regulation of cyclin dependent protein serine threonine kinase activity involved in g1 s transition of mitotic cell cycle GO:0031657 9 0.135
negative regulation of transmembrane transport GO:0034763 29 0.134
positive regulation of calcium ion transport GO:0051928 51 0.134
chemical homeostasis GO:0048878 306 0.133
Rat
cellular response to abiotic stimulus GO:0071214 117 0.132
tube development GO:0035295 125 0.132
heart development GO:0007507 95 0.131
maintenance of protein location GO:0045185 57 0.129
Mouse
cell cycle phase transition GO:0044770 173 0.128
muscle tissue development GO:0060537 62 0.126
purine nucleoside triphosphate catabolic process GO:0009146 392 0.126
regulation of protein transport GO:0051223 213 0.125
Mouse
maintenance of protein location in cell GO:0032507 56 0.124
Mouse
pronephros morphogenesis GO:0072114 1 0.123
ribonucleoside triphosphate metabolic process GO:0009199 412 0.121
regulation of transporter activity GO:0032409 82 0.121
positive regulation of protein kinase activity GO:0045860 190 0.120
regulation of cell migration GO:0030334 289 0.119
behavior GO:0007610 112 0.117
regulation of cation channel activity GO:2001257 33 0.116
multicellular organismal metabolic process GO:0044236 34 0.116
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.115
mesenchyme development GO:0060485 59 0.114
regulation of blood circulation GO:1903522 59 0.114
negative regulation of ion transmembrane transport GO:0034766 26 0.114
determination of adult lifespan GO:0008340 2 0.114
regulation of protein localization to nucleus GO:1900180 85 0.113
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 9 0.112
negative regulation of transporter activity GO:0032410 25 0.112
nephron tubule development GO:0072080 17 0.112
positive regulation of ion transmembrane transport GO:0034767 40 0.112
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.112
Rat
protein targeting to nucleus GO:0044744 104 0.111
Mouse
nucleocytoplasmic transport GO:0006913 176 0.110
Mouse
post embryonic development GO:0009791 2 0.108
purine nucleotide catabolic process GO:0006195 405 0.108
regulation of cell cycle phase transition GO:1901987 126 0.106
mesonephric tubule morphogenesis GO:0072171 10 0.106
regulation of system process GO:0044057 101 0.106
organ morphogenesis GO:0009887 147 0.105
vesicle mediated transport GO:0016192 371 0.103
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.103
ion homeostasis GO:0050801 230 0.103
Rat
heart morphogenesis GO:0003007 48 0.102
negative regulation of protein localization to nucleus GO:1900181 34 0.101
Mouse
embryonic heart tube morphogenesis GO:0003143 8 0.101
cellular homeostasis GO:0019725 196 0.100
Rat
ribonucleoside catabolic process GO:0042454 406 0.100
pronephros development GO:0048793 2 0.100
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.099
small gtpase mediated signal transduction GO:0007264 78 0.097
regulation of intracellular protein transport GO:0033157 123 0.097
Mouse
kidney vasculature development GO:0061440 7 0.097
response to abiotic stimulus GO:0009628 336 0.096
Mouse
response to mechanical stimulus GO:0009612 51 0.096
Mouse
regulation of cell cycle g1 s phase transition GO:1902806 42 0.095
regulation of intracellular transport GO:0032386 195 0.094
Mouse
negative regulation of transport GO:0051051 176 0.093
Mouse
g1 s transition of mitotic cell cycle GO:0000082 78 0.092
positive regulation of calcium ion transmembrane transporter activity GO:1901021 13 0.091
nucleoside phosphate catabolic process GO:1901292 412 0.091
regulation of anatomical structure morphogenesis GO:0022603 286 0.090
purine ribonucleoside catabolic process GO:0046130 398 0.090
epithelial tube morphogenesis GO:0060562 38 0.088
metal ion homeostasis GO:0055065 169 0.088
Rat
purine nucleoside catabolic process GO:0006152 398 0.085
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 29 0.084
positive regulation of transporter activity GO:0032411 32 0.084
single organism nuclear import GO:1902593 104 0.082
Mouse
multicellular organismal aging GO:0010259 3 0.081
negative regulation of intracellular transport GO:0032387 60 0.081
Mouse
regulation of axon guidance GO:1902667 3 0.081
negative regulation of cell cycle process GO:0010948 121 0.079
negative regulation of cell cycle phase transition GO:1901988 89 0.079
ras protein signal transduction GO:0007265 73 0.079
regulation of calcium ion import GO:0090279 11 0.079
response to oxygen containing compound GO:1901700 369 0.078
neural tube development GO:0021915 9 0.077
ureteric bud morphogenesis GO:0060675 10 0.077
cellular response to acid chemical GO:0071229 44 0.077
branching morphogenesis of an epithelial tube GO:0048754 19 0.077
embryonic morphogenesis GO:0048598 85 0.076
taxis GO:0042330 157 0.074
kidney development GO:0001822 53 0.074
cell cycle g1 s phase transition GO:0044843 80 0.074
multicellular organismal macromolecule metabolic process GO:0044259 29 0.073
jak stat cascade GO:0007259 46 0.073
Mouse
regulation of cytoplasmic transport GO:1903649 149 0.073
Mouse
ureteric bud development GO:0001657 13 0.073
oogenesis GO:0048477 2 0.072
chemotaxis GO:0006935 157 0.072
regulation of receptor activity GO:0010469 47 0.071
positive regulation of cell proliferation GO:0008284 301 0.070
regionalization GO:0003002 29 0.070
aorta development GO:0035904 2 0.070
smooth muscle tissue development GO:0048745 3 0.069
response to acid chemical GO:0001101 66 0.069
positive regulation of gtpase activity GO:0043547 166 0.068
regulation of transcription factor import into nucleus GO:0042990 39 0.067
Mouse
collagen biosynthetic process GO:0032964 15 0.066
regulation of multicellular organismal metabolic process GO:0044246 17 0.066
female gamete generation GO:0007292 2 0.066
regulation of gtp catabolic process GO:0033124 180 0.065
purine nucleoside triphosphate metabolic process GO:0009144 412 0.064
neuromuscular junction development GO:0007528 3 0.064
tissue morphogenesis GO:0048729 96 0.062
negative regulation of protein import into nucleus GO:0042308 30 0.062
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 391 0.061
organophosphate catabolic process GO:0046434 430 0.061
positive regulation of cellular component organization GO:0051130 376 0.061
determination of liver left right asymmetry GO:0071910 6 0.061
gland development GO:0048732 48 0.061
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.061
negative regulation of ion transport GO:0043271 39 0.060
negative regulation of homeostatic process GO:0032845 59 0.060
regulation of cell motility GO:2000145 299 0.060
glycosyl compound catabolic process GO:1901658 413 0.060
regulation of purine nucleotide catabolic process GO:0033121 205 0.060
cellular divalent inorganic cation homeostasis GO:0072503 128 0.059
Rat
regulation of ion homeostasis GO:2000021 73 0.059
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.059
Mouse
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.059
blood vessel morphogenesis GO:0048514 162 0.059
response to inorganic substance GO:0010035 127 0.058
guanosine containing compound catabolic process GO:1901069 239 0.058
positive regulation of catabolic process GO:0009896 310 0.057
regulation of neuron differentiation GO:0045664 70 0.055
release of sequestered calcium ion into cytosol GO:0051209 41 0.055
apoptotic signaling pathway GO:0097190 268 0.054
negative regulation of intracellular protein transport GO:0090317 42 0.054
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.054
nucleoside catabolic process GO:0009164 408 0.053
positive regulation of locomotion GO:0040017 186 0.053
negative regulation of sequestering of calcium ion GO:0051283 41 0.053
secretion GO:0046903 254 0.052
detection of abiotic stimulus GO:0009582 15 0.052
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.051
regulation of nucleoside metabolic process GO:0009118 209 0.051
nucleoside triphosphate catabolic process GO:0009143 394 0.051
regulation of nucleotide catabolic process GO:0030811 205 0.051
purine ribonucleoside metabolic process GO:0046128 437 0.051
cytosolic calcium ion transport GO:0060401 48 0.051
gtp catabolic process GO:0006184 237 0.050
cytoplasmic transport GO:0016482 379 0.050
Mouse
lymph vessel morphogenesis GO:0036303 7 0.050
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.050
neurogenesis GO:0022008 169 0.050
cellular component morphogenesis GO:0032989 314 0.049
central nervous system development GO:0007417 123 0.049
endomembrane system organization GO:0010256 196 0.049
regulation of sequestering of calcium ion GO:0051282 41 0.049
regulation of mapk cascade GO:0043408 262 0.049
regulation of ryanodine sensitive calcium release channel activity GO:0060314 12 0.049
regulation of cellular amino acid metabolic process GO:0006521 6 0.049
regulation of gtpase activity GO:0043087 180 0.048
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.048
purine containing compound catabolic process GO:0072523 411 0.046
determination of bilateral symmetry GO:0009855 15 0.046
negative regulation of phosphate metabolic process GO:0045936 267 0.046
ribonucleotide catabolic process GO:0009261 405 0.046
actin filament based process GO:0030029 224 0.046
nucleotide catabolic process GO:0009166 408 0.046
membrane organization GO:0061024 292 0.046
segmentation GO:0035282 4 0.045
maintenance of location GO:0051235 112 0.045
Mouse
positive regulation of cation channel activity GO:2001259 16 0.045
regulation of nitric oxide biosynthetic process GO:0045428 17 0.044
negative regulation of mitotic cell cycle GO:0045930 102 0.044
guanosine containing compound metabolic process GO:1901068 244 0.044
tube morphogenesis GO:0035239 95 0.043
cell morphogenesis involved in differentiation GO:0000904 144 0.043
negative regulation of ion transmembrane transporter activity GO:0032413 19 0.043
cardiovascular system development GO:0072358 262 0.042
neuron projection development GO:0031175 106 0.042
morphogenesis of a branching epithelium GO:0061138 20 0.042
g protein coupled receptor signaling pathway GO:0007186 207 0.042
calcium ion transport into cytosol GO:0060402 48 0.042
nitric oxide metabolic process GO:0046209 22 0.041
regulation of collagen metabolic process GO:0010712 15 0.041
heart looping GO:0001947 7 0.040
embryo development GO:0009790 123 0.040
regulation of collagen biosynthetic process GO:0032965 11 0.040
single organism reproductive process GO:0044702 98 0.039
calcium ion transport GO:0006816 147 0.039
Human Mouse
regulation of cellular response to stress GO:0080135 244 0.039
positive regulation of nitric oxide biosynthetic process GO:0045429 13 0.039
cell morphogenesis GO:0000902 296 0.039
oocyte differentiation GO:0009994 2 0.038
cytokine production GO:0001816 247 0.038
regulation of cellular component biogenesis GO:0044087 281 0.038
carbohydrate derivative biosynthetic process GO:1901137 207 0.038
cytosolic calcium ion homeostasis GO:0051480 89 0.037
Rat
lymphangiogenesis GO:0001946 7 0.037
endosomal transport GO:0016197 129 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
mapk cascade GO:0000165 288 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.037
positive regulation of gtp catabolic process GO:0033126 166 0.037
response to osmotic stress GO:0006970 17 0.037
negative regulation of phosphorus metabolic process GO:0010563 267 0.037
dorsal ventral pattern formation GO:0009953 15 0.037
negative regulation of calcium ion transport GO:0051926 19 0.036
nitric oxide biosynthetic process GO:0006809 20 0.036
positive regulation of cell differentiation GO:0045597 211 0.036
cell substrate adhesion GO:0031589 132 0.036
signal transduction by phosphorylation GO:0023014 297 0.036
positive regulation of nucleotide catabolic process GO:0030813 185 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.035
protein localization to membrane GO:0072657 160 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
negative regulation of calcium ion transmembrane transport GO:1903170 11 0.035
regulation of cell projection organization GO:0031344 107 0.034
gtp metabolic process GO:0046039 239 0.034
regulation of cell differentiation GO:0045595 393 0.034
spermatid differentiation GO:0048515 4 0.034
chordate embryonic development GO:0043009 34 0.033
biological adhesion GO:0022610 331 0.033
Mouse
negative regulation of catalytic activity GO:0043086 335 0.032
positive regulation of apoptotic process GO:0043065 246 0.032
negative regulation of cation channel activity GO:2001258 12 0.032
kidney mesenchyme development GO:0072074 1 0.032
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.031
blastoderm segmentation GO:0007350 2 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
rho protein signal transduction GO:0007266 26 0.030
neuron projection morphogenesis GO:0048812 50 0.030
regulation of nervous system development GO:0051960 88 0.030
proteoglycan metabolic process GO:0006029 29 0.030
locomotory behavior GO:0007626 1 0.030
carbohydrate metabolic process GO:0005975 207 0.030
determination of heart left right asymmetry GO:0061371 8 0.030
cell matrix adhesion GO:0007160 85 0.029
actin cytoskeleton organization GO:0030036 207 0.029
cell projection assembly GO:0030031 126 0.029
ion transmembrane transport GO:0034220 338 0.029
Human Mouse
cellular ketone metabolic process GO:0042180 80 0.028
sensory perception of mechanical stimulus GO:0050954 37 0.028
artery morphogenesis GO:0048844 7 0.028
regulation of response to external stimulus GO:0032101 222 0.028
specification of symmetry GO:0009799 16 0.028
developmental process involved in reproduction GO:0003006 66 0.028
circulatory system development GO:0072359 262 0.028
reproductive system development GO:0061458 56 0.027
positive regulation of cell motility GO:2000147 177 0.027
negative regulation of calcium ion transmembrane transporter activity GO:1901020 11 0.027
positive regulation of nucleotide metabolic process GO:0045981 230 0.027
positive regulation of cellular amine metabolic process GO:0033240 7 0.027
reproduction GO:0000003 63 0.027
regulation of homeostatic process GO:0032844 121 0.026
cilium organization GO:0044782 68 0.026
negative regulation of apoptotic process GO:0043066 316 0.026
associative learning GO:0008306 1 0.026
response to wounding GO:0009611 168 0.026
kidney vasculature morphogenesis GO:0061439 1 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.026
growth GO:0040007 202 0.026
placenta development GO:0001890 10 0.026
Mouse
microtubule cytoskeleton organization GO:0000226 176 0.025
Mouse
covalent chromatin modification GO:0016569 254 0.025
mitotic cell cycle process GO:1903047 286 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
morphogenesis of a branching structure GO:0001763 21 0.024
single organism carbohydrate metabolic process GO:0044723 193 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
lipid transport GO:0006869 90 0.024
regulation of jnk cascade GO:0046328 73 0.024
glycoprotein metabolic process GO:0009100 110 0.024
metanephric part of ureteric bud development GO:0035502 2 0.024
cell fate determination GO:0001709 3 0.024
regulation of canonical wnt signaling pathway GO:0060828 88 0.024
cell part morphogenesis GO:0032990 137 0.024
anterior posterior axis specification GO:0009948 2 0.024
single organism membrane organization GO:0044802 268 0.023
lymph vessel development GO:0001945 9 0.023
Mouse
rhythmic behavior GO:0007622 2 0.023
morphogenesis of embryonic epithelium GO:0016331 4 0.023
immune response GO:0006955 307 0.023
negative regulation of cell death GO:0060548 345 0.023
amine metabolic process GO:0009308 44 0.022
cellular response to osmotic stress GO:0071470 8 0.022
negative regulation of intracellular signal transduction GO:1902532 183 0.022
cell cell signaling GO:0007267 155 0.022
hepaticobiliary system development GO:0061008 10 0.022
Mouse
regulation of cell adhesion GO:0030155 166 0.022
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.021
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.021
hindbrain development GO:0030902 3 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
organ formation GO:0048645 3 0.021
defense response GO:0006952 315 0.021
pattern specification process GO:0007389 43 0.021
positive regulation of kinase activity GO:0033674 204 0.021
organonitrogen compound biosynthetic process GO:1901566 200 0.021
morphogenesis of an epithelium GO:0002009 60 0.020
head development GO:0060322 108 0.020
organelle fission GO:0048285 149 0.020
regulation of cellular component size GO:0032535 82 0.020
cellular amino acid metabolic process GO:0006520 116 0.020
cell activation GO:0001775 213 0.020
protein ubiquitination GO:0016567 314 0.020
endochondral bone morphogenesis GO:0060350 3 0.020
oocyte development GO:0048599 1 0.020
reproductive process GO:0022414 106 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
protein localization to plasma membrane GO:0072659 93 0.020
regulation of epithelial cell migration GO:0010632 93 0.019
negative regulation of developmental process GO:0051093 247 0.019
divalent inorganic cation homeostasis GO:0072507 136 0.019
Rat
multicellular organism reproduction GO:0032504 42 0.019
motor neuron axon guidance GO:0008045 2 0.019
regulation of map kinase activity GO:0043405 108 0.019
regulation of ras protein signal transduction GO:0046578 155 0.019
negative regulation of cellular component movement GO:0051271 106 0.019
response to organonitrogen compound GO:0010243 156 0.018
detection of external stimulus GO:0009581 15 0.018
Mouse
neurological system process GO:0050877 163 0.018
memory GO:0007613 3 0.018
multi organism reproductive process GO:0044703 54 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
skeletal system development GO:0001501 79 0.018
plasma membrane organization GO:0007009 115 0.018
renal system vasculature morphogenesis GO:0061438 1 0.018
neuron development GO:0048666 113 0.018
regulation of protein localization GO:0032880 296 0.018
Mouse
negative regulation of hydrolase activity GO:0051346 182 0.018
regulation of neurogenesis GO:0050767 82 0.018
intrinsic apoptotic signaling pathway GO:0097193 127 0.017
neurotransmitter secretion GO:0007269 4 0.017
regulation of stress activated mapk cascade GO:0032872 84 0.017
cellular macromolecular complex assembly GO:0034622 324 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
hematopoietic or lymphoid organ development GO:0048534 186 0.017
determination of left right symmetry GO:0007368 11 0.017
nuclear division GO:0000280 128 0.017
single organismal cell cell adhesion GO:0016337 148 0.017
Mouse
negative regulation of protein modification process GO:0031400 200 0.017
ossification GO:0001503 121 0.017
liver development GO:0001889 9 0.017
Mouse
multicellular organismal reproductive process GO:0048609 40 0.016
organelle assembly GO:0070925 176 0.016
positive regulation of developmental process GO:0051094 314 0.016
response to low density lipoprotein particle GO:0055098 4 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
melanin metabolic process GO:0006582 1 0.016
reproductive structure development GO:0048608 55 0.016
organic hydroxy compound metabolic process GO:1901615 147 0.016
negative regulation of cell migration GO:0030336 102 0.016
cell cell junction organization GO:0045216 69 0.016
cell type specific apoptotic process GO:0097285 125 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
retinal ganglion cell axon guidance GO:0031290 2 0.016
embryonic organ development GO:0048568 36 0.016
Mouse
positive regulation of hydrolase activity GO:0051345 331 0.016
regulation of protein complex assembly GO:0043254 147 0.016
sensory perception of light stimulus GO:0050953 35 0.015
cell junction organization GO:0034330 79 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
protein modification by small protein conjugation GO:0032446 342 0.015

PKD1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.117
muscular disease DOID:0080000 114 0.036
myopathy DOID:423 104 0.033
muscle tissue disease DOID:66 113 0.033
connective tissue disease DOID:65 109 0.017
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015