IMP

Process View

Homo sapiens

17 genes annotated in human

mesonephros development

The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesonephros development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesonephros development" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD3	SMAD family member 3	1.000	Mouse
SMAD2	SMAD family member 2	0.999	Mouse
SMAD1	SMAD family member 1	0.998	Mouse
FGFR1	fibroblast growth factor receptor 1	0.971	Mouse
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.969
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.966
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.931
MSN	moesin	0.842
EGR3	early growth response 3	0.819	Human
EGR1	early growth response 1	0.812	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.716
RXRA	retinoid X receptor, alpha	0.670
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.617
MEIS1	Meis homeobox 1	0.532
EGR2	early growth response 2	0.526	Human
SMAD5	SMAD family member 5	0.504	Mouse
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.499
SMAD7	SMAD family member 7	0.477	Mouse
NKX2-1	NK2 homeobox 1	0.436
MEIS2	Meis homeobox 2	0.399
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.381
BMPR1B	bone morphogenetic protein receptor, type IB	0.377
BMP7	bone morphogenetic protein 7	0.346
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.337
NOG	noggin	0.311	Mouse
SMAD4	SMAD family member 4	0.246	Mouse
WNT1	wingless-type MMTV integration site family, member 1	0.241	Human Mouse
PAX8	paired box 8	0.237
SPRY2	sprouty homolog 2 (Drosophila)	0.233
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.231
NRP1	neuropilin 1	0.231
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.223
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.220
TGFB3	transforming growth factor, beta 3	0.215
SKIL	SKI-like oncogene	0.209
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.203
COL2A1	collagen, type II, alpha 1	0.199
PLCG1	phospholipase C, gamma 1	0.188
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.183
FGF18	fibroblast growth factor 18	0.173	Human
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.160
FGFR2	fibroblast growth factor receptor 2	0.156	Mouse
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.156
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.155
BCL2L1	BCL2-like 1	0.151
PJA1	praja ring finger 1	0.141
SFRP1	secreted frizzled-related protein 1	0.134	Mouse
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.133
ENG	endoglin	0.129
SMAD6	SMAD family member 6	0.118	Mouse
CPE	carboxypeptidase E	0.115
FGF2	fibroblast growth factor 2 (basic)	0.109
WNT7A	wingless-type MMTV integration site family, member 7A	0.106	Human
TIMP3	TIMP metallopeptidase inhibitor 3	0.106
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.105
FGF8	fibroblast growth factor 8 (androgen-induced)	0.103
THBS1	thrombospondin 1	0.100
CCNE1	cyclin E1	0.098
TGFBR1	transforming growth factor, beta receptor 1	0.097
FGF4	fibroblast growth factor 4	0.097	Human
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.097
MYOD1	myogenic differentiation 1	0.095
BMP4	bone morphogenetic protein 4	0.094
FGF1	fibroblast growth factor 1 (acidic)	0.092
BMP2	bone morphogenetic protein 2	0.088	Human Mouse
FOXF1	forkhead box F1	0.080
IER2	immediate early response 2	0.076
TGFB2	transforming growth factor, beta 2	0.076
MAGED2	melanoma antigen family D, 2	0.075
ADAM17	ADAM metallopeptidase domain 17	0.073
ACAN	aggrecan	0.072
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.068
SOX1	SRY (sex determining region Y)-box 1	0.068
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.062
HOXA10	homeobox A10	0.062
FOXC1	forkhead box C1	0.062	Mouse
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.059
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.059
FOXF2	forkhead box F2	0.051
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.050
TBX2	T-box 2	0.049
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.044
SOX2	SRY (sex determining region Y)-box 2	0.044
INHBB	inhibin, beta B	0.041
FGF3	fibroblast growth factor 3	0.040	Human
GATA2	GATA binding protein 2	0.039
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.039
PAX3	paired box 3	0.038
HOXC8	homeobox C8	0.038
WNT11	wingless-type MMTV integration site family, member 11	0.035
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.035
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.035
PARVA	parvin, alpha	0.034
LHX1	LIM homeobox 1	0.034	Mouse Rat
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.033
FGF10	fibroblast growth factor 10	0.033
GAS1	growth arrest-specific 1	0.031
SMAD9	SMAD family member 9	0.030	Mouse
FRS2	fibroblast growth factor receptor substrate 2	0.030
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.029
COL7A1	collagen, type VII, alpha 1	0.029
PITX2	paired-like homeodomain 2	0.029
CXXC5	CXXC finger protein 5	0.029
AQP5	aquaporin 5	0.028
FOXA2	forkhead box A2	0.028
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.027
GDNF	glial cell derived neurotrophic factor	0.027
PDX1	pancreatic and duodenal homeobox 1	0.027
IHH	Indian hedgehog	0.027
SIX2	SIX homeobox 2	0.027	Mouse
FBXW7	F-box and WD repeat domain containing 7	0.027
SIM2	single-minded homolog 2 (Drosophila)	0.026
LBX1	ladybird homeobox 1	0.025
FGFR3	fibroblast growth factor receptor 3	0.025
NPAS1	neuronal PAS domain protein 1	0.024
PBK	PDZ binding kinase	0.024
FOXD3	forkhead box D3	0.024
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.024
WIF1	WNT inhibitory factor 1	0.024
SIX1	SIX homeobox 1	0.023	Mouse
COL13A1	collagen, type XIII, alpha 1	0.023
WNT2	wingless-type MMTV integration site family member 2	0.023	Human
FZD10	frizzled homolog 10 (Drosophila)	0.023
HOXB5	homeobox B5	0.023
SRGN	serglycin	0.022
CCND1	cyclin D1	0.022
HOXA11	homeobox A11	0.022	Mouse
NEUROG2	neurogenin 2	0.022
SOD3	superoxide dismutase 3, extracellular	0.022
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.021
WNT3	wingless-type MMTV integration site family, member 3	0.021	Human
DLX4	distal-less homeobox 4	0.021
EYA2	eyes absent homolog 2 (Drosophila)	0.021
SLIT2	slit homolog 2 (Drosophila)	0.021
BMP8A	bone morphogenetic protein 8a	0.021	Human
COL14A1	collagen, type XIV, alpha 1	0.020
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.020
CRLF1	cytokine receptor-like factor 1	0.020	Mouse
RUNX1	runt-related transcription factor 1	0.020
BTG2	BTG family, member 2	0.020
RAX	retina and anterior neural fold homeobox	0.020
WNT4	wingless-type MMTV integration site family, member 4	0.020	Human
HOXD13	homeobox D13	0.020
ELN	elastin	0.019
JAG1	jagged 1	0.019
FZD7	frizzled homolog 7 (Drosophila)	0.019
SSR1	signal sequence receptor, alpha	0.019
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.019
VSX1	visual system homeobox 1	0.019
FBLN1	fibulin 1	0.019
VEGFC	vascular endothelial growth factor C	0.018
IGFBP5	insulin-like growth factor binding protein 5	0.018
SIX3	SIX homeobox 3	0.018
FOXL1	forkhead box L1	0.018
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.018
RET	ret proto-oncogene	0.018	Mouse
SFRP4	secreted frizzled-related protein 4	0.017
DUSP6	dual specificity phosphatase 6	0.017
PAX2	paired box 2	0.017
SOX9	SRY (sex determining region Y)-box 9	0.017	Mouse
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.017
PGR	progesterone receptor	0.017
PRRX2	paired related homeobox 2	0.016
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.016
TCF21	transcription factor 21	0.016	Mouse
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.016
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.016
FZD8	frizzled homolog 8 (Drosophila)	0.016
WT1	Wilms tumor 1	0.016
GCSH	glycine cleavage system protein H (aminomethyl carrier)	0.016
HOXD10	homeobox D10	0.016
WNT6	wingless-type MMTV integration site family, member 6	0.016	Human
ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	0.016
CARD10	caspase recruitment domain family, member 10	0.015
HNF1A	HNF1 homeobox A	0.015
CXCL12	chemokine (C-X-C motif) ligand 12	0.015
MNX1	motor neuron and pancreas homeobox 1	0.015
GPC3	glypican 3	0.015
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.015
NKX3-2	NK3 homeobox 2	0.015
DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	0.015
SCARF2	scavenger receptor class F, member 2	0.015
EYA1	eyes absent homolog 1 (Drosophila)	0.015
RXRB	retinoid X receptor, beta	0.014
GJA3	gap junction protein, alpha 3, 46kDa	0.014
GFRA1	GDNF family receptor alpha 1	0.014
PUM1	pumilio homolog 1 (Drosophila)	0.014
FOXN4	forkhead box N4	0.014
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.014
HAND1	heart and neural crest derivatives expressed 1	0.014
PTHLH	parathyroid hormone-like hormone	0.014
HMGA2	high mobility group AT-hook 2	0.014
SIX6	SIX homeobox 6	0.014
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.014
CLDN1	claudin 1	0.014
LDLR	low density lipoprotein receptor	0.014
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.014
ITGA8	integrin, alpha 8	0.014
HOXA13	homeobox A13	0.014
TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.013
KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.013
FOXB1	forkhead box B1	0.013
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.013
BBS1	Bardet-Biedl syndrome 1	0.013
HOXB1	homeobox B1	0.013
PTPRB	protein tyrosine phosphatase, receptor type, B	0.013
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.013
ALX4	ALX homeobox 4	0.013
A4GALT	alpha 1,4-galactosyltransferase	0.013
DIO3	deiodinase, iodothyronine, type III	0.013
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.013
GATA6	GATA binding protein 6	0.013
HES2	hairy and enhancer of split 2 (Drosophila)	0.013
CYR61	cysteine-rich, angiogenic inducer, 61	0.013
HBEGF	heparin-binding EGF-like growth factor	0.013
FOXA1	forkhead box A1	0.013
NPPC	natriuretic peptide C	0.013
ZNF205	zinc finger protein 205	0.012
TBX3	T-box 3	0.012
SVEP1	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	0.012
SOX11	SRY (sex determining region Y)-box 11	0.012
TGFBR3	transforming growth factor, beta receptor III	0.012
STC1	stanniocalcin 1	0.012
SNAI1	snail homolog 1 (Drosophila)	0.012
KISS1	KiSS-1 metastasis-suppressor	0.012
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.012
HOXC5	homeobox C5	0.012
CAPN6	calpain 6	0.012
SOX7	SRY (sex determining region Y)-box 7	0.012
GSC	goosecoid homeobox	0.012
HOXB9	homeobox B9	0.012
CREBBP	CREB binding protein	0.012
RARB	retinoic acid receptor, beta	0.012	Mouse
MED25	mediator complex subunit 25	0.012
EFNB3	ephrin-B3	0.012
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.012
FBLN2	fibulin 2	0.012
NPHP1	nephronophthisis 1 (juvenile)	0.012
HIC1	hypermethylated in cancer 1	0.012
RUNX2	runt-related transcription factor 2	0.012
TBX1	T-box 1	0.011
TCF4	transcription factor 4	0.011
ANGPT4	angiopoietin 4	0.011
HOXD11	homeobox D11	0.011	Mouse
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.011
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.011
DLX2	distal-less homeobox 2	0.011
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.011
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.011
JUNB	jun B proto-oncogene	0.011
RARG	retinoic acid receptor, gamma	0.011
HOXD9	homeobox D9	0.011
TAL1	T-cell acute lymphocytic leukemia 1	0.011
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.011
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.011
TG	thyroglobulin	0.011
CALCA	calcitonin-related polypeptide alpha	0.011
PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	0.011
EPHA8	EPH receptor A8	0.011
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.011
HMX1	H6 family homeobox 1	0.011
RBMS3	RNA binding motif, single stranded interacting protein 3	0.010
PAX7	paired box 7	0.010
CTGF	connective tissue growth factor	0.010
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.010
FSCN2	fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)	0.010
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.010
CADM4	cell adhesion molecule 4	0.010
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.010
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.010
TACR1	tachykinin receptor 1	0.010
STK36	serine/threonine kinase 36	0.010
THBS2	thrombospondin 2	0.010
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.010
CLDN7	claudin 7	0.010
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.010
C1QL1	complement component 1, q subcomponent-like 1	0.010
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.010
DUSP2	dual specificity phosphatase 2	0.010
HAS2	hyaluronan synthase 2	0.010
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.010
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.010