Homo sapiens

303 known processes

RAPGEF2

Rap guanine nucleotide exchange factor (GEF) 2

(Aliases: nRap GEP,RA-GEF,PDZ-GEF1,PDZGEF1,NRAPGEP,Rap-GEP,CNrasGEF)

RAPGEF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of cell development GO:0010720 92 0.827
Mouse Rat
cellular response to nerve growth factor stimulus GO:1990090 6 0.803
Rat
nucleoside catabolic process GO:0009164 408 0.795
cellular response to growth factor stimulus GO:0071363 197 0.669
Rat
positive regulation of cell differentiation GO:0045597 211 0.666
Mouse Rat
nerve growth factor signaling pathway GO:0038180 4 0.594
Rat
positive regulation of catabolic process GO:0009896 310 0.583
drinking behavior GO:0042756 1 0.571
nucleoside triphosphate metabolic process GO:0009141 422 0.565
regulation of cell differentiation GO:0045595 393 0.558
ribonucleoside triphosphate metabolic process GO:0009199 412 0.551
cellular component morphogenesis GO:0032989 314 0.533
purine ribonucleotide catabolic process GO:0009154 404 0.527
cellular ketone metabolic process GO:0042180 80 0.524
regulation of neuron projection development GO:0010975 57 0.503
response to nerve growth factor GO:1990089 6 0.497
Rat
regulation of cellular ketone metabolic process GO:0010565 50 0.489
cell development GO:0048468 328 0.483
organophosphate catabolic process GO:0046434 430 0.473
negative regulation of synaptic transmission GO:0050805 2 0.467
protein modification by small protein conjugation GO:0032446 342 0.454
neuron differentiation GO:0030182 138 0.452
negative regulation of transport GO:0051051 176 0.441
nervous system development GO:0007399 293 0.426
response to growth factor GO:0070848 205 0.420
Rat
ras protein signal transduction GO:0007265 73 0.412
ribonucleoside triphosphate catabolic process GO:0009203 391 0.412
nucleoside phosphate catabolic process GO:1901292 412 0.405
positive regulation of ras gtpase activity GO:0032320 117 0.405
cellular response to endogenous stimulus GO:0071495 336 0.404
positive regulation of cellular component organization GO:0051130 376 0.400
Human Rat
positive regulation of cell projection organization GO:0031346 64 0.395
Rat
positive regulation of neuron projection development GO:0010976 34 0.377
Rat
receptor internalization GO:0031623 43 0.373
purine ribonucleoside metabolic process GO:0046128 437 0.353
cytoplasmic transport GO:0016482 379 0.344
neurotransmitter secretion GO:0007269 4 0.338
purine containing compound catabolic process GO:0072523 411 0.336
system process GO:0003008 349 0.334
positive regulation of cellular catabolic process GO:0031331 284 0.330
establishment of organelle localization GO:0051656 59 0.326
response to oxygen containing compound GO:1901700 369 0.310
regulation of transferase activity GO:0051338 355 0.310
segmentation GO:0035282 4 0.308
neuron projection development GO:0031175 106 0.302
response to salt stress GO:0009651 3 0.299
purine ribonucleoside catabolic process GO:0046130 398 0.297
regulation of cellular component biogenesis GO:0044087 281 0.293
ion transmembrane transport GO:0034220 338 0.286
regulation of neuron differentiation GO:0045664 70 0.285
regulation of kinase activity GO:0043549 314 0.281
regulation of vesicle mediated transport GO:0060627 130 0.280
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.275
cell morphogenesis involved in differentiation GO:0000904 144 0.269
regulation of synaptic vesicle exocytosis GO:2000300 2 0.266
sodium ion transmembrane transport GO:0035725 59 0.262
regulation of cell projection organization GO:0031344 107 0.261
regulation of cell development GO:0060284 161 0.257
positive regulation of gtpase activity GO:0043547 166 0.256
glycosyl compound catabolic process GO:1901658 413 0.254
cell junction organization GO:0034330 79 0.253
gtp catabolic process GO:0006184 237 0.252
cardiovascular system development GO:0072358 262 0.249
Human Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.233
positive regulation of neuron differentiation GO:0045666 40 0.230
Rat
positive regulation of mapk cascade GO:0043410 190 0.230
neuron development GO:0048666 113 0.228
regulation of neurotransmitter secretion GO:0046928 3 0.227
nucleoside triphosphate catabolic process GO:0009143 394 0.226
regulation of cellular amine metabolic process GO:0033238 11 0.224
erk1 and erk2 cascade GO:0070371 104 0.217
positive regulation of hydrolase activity GO:0051345 331 0.214
regulation of vasculogenesis GO:2001212 3 0.210
Mouse
cellular amino acid metabolic process GO:0006520 116 0.210
regulation of receptor mediated endocytosis GO:0048259 32 0.209
protein autophosphorylation GO:0046777 123 0.207
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.207
lipid metabolic process GO:0006629 381 0.204
positive regulation of transport GO:0051050 336 0.203
single organism cellular localization GO:1902580 332 0.201
circulatory system development GO:0072359 262 0.198
Human Mouse
regulation of actin filament based process GO:0032970 141 0.197
Human
lipid biosynthetic process GO:0008610 177 0.196
vesicle mediated transport GO:0016192 371 0.196
regulation of dendrite development GO:0050773 18 0.193
glomerular visceral epithelial cell development GO:0072015 2 0.192
regulation of system process GO:0044057 101 0.192
cell projection morphogenesis GO:0048858 129 0.188
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.188
regulation of nucleotide catabolic process GO:0030811 205 0.186
cell projection organization GO:0030030 252 0.184
renal filtration cell differentiation GO:0061318 4 0.184
positive regulation of developmental process GO:0051094 314 0.181
Human Mouse Rat
positive regulation of phosphorylation GO:0042327 394 0.178
transmembrane transport GO:0055085 399 0.173
regulation of neurogenesis GO:0050767 82 0.172
positive regulation of lipid biosynthetic process GO:0046889 22 0.168
mapk cascade GO:0000165 288 0.167
negative regulation of apoptotic process GO:0043066 316 0.163
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.162
cellular response to organonitrogen compound GO:0071417 124 0.161
synaptic vesicle exocytosis GO:0016079 3 0.159
response to biotic stimulus GO:0009607 276 0.155
enzyme linked receptor protein signaling pathway GO:0007167 303 0.155
Rat
regulation of protein transport GO:0051223 213 0.152
positive regulation of protein phosphorylation GO:0001934 313 0.150
protein localization to membrane GO:0072657 160 0.149
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 45 0.148
positive regulation of nucleotide catabolic process GO:0030813 185 0.145
gtp metabolic process GO:0046039 239 0.142
wound healing GO:0042060 115 0.142
cellular macromolecule catabolic process GO:0044265 380 0.141
dephosphorylation GO:0016311 209 0.140
somitogenesis GO:0001756 2 0.139
negative regulation of cell proliferation GO:0008285 228 0.138
purine nucleotide catabolic process GO:0006195 405 0.138
positive regulation of transferase activity GO:0051347 227 0.137
protein ubiquitination GO:0016567 314 0.136
multi organism cellular process GO:0044764 156 0.136
inorganic cation transmembrane transport GO:0098662 194 0.135
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.134
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.133
coenzyme metabolic process GO:0006732 65 0.132
regulation of cell morphogenesis GO:0022604 153 0.131
positive regulation of neurogenesis GO:0050769 49 0.131
Mouse Rat
anterior posterior axis specification GO:0009948 2 0.130
positive regulation of cellular amine metabolic process GO:0033240 7 0.129
positive regulation of nucleoside metabolic process GO:0045979 186 0.129
blood vessel morphogenesis GO:0048514 162 0.128
Human Mouse
cellular response to camp GO:0071320 21 0.128
monovalent inorganic cation transport GO:0015672 128 0.127
regulation of proteasomal protein catabolic process GO:0061136 87 0.127
regulation of potassium ion transmembrane transport GO:1901379 20 0.124
purine nucleoside catabolic process GO:0006152 398 0.121
cellular lipid metabolic process GO:0044255 303 0.121
ribonucleoside monophosphate catabolic process GO:0009158 158 0.118
small gtpase mediated signal transduction GO:0007264 78 0.118
regulation of ion transmembrane transport GO:0034765 132 0.117
receptor catabolic process GO:0032801 11 0.115
regulation of protein catabolic process GO:0042176 155 0.115
response to nitrogen compound GO:1901698 184 0.115
glomerular epithelial cell development GO:0072310 3 0.113
cell adhesion GO:0007155 325 0.113
endosome transport via multivesicular body sorting pathway GO:0032509 3 0.113
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.112
regulation of nucleoside metabolic process GO:0009118 209 0.111
kidney development GO:0001822 53 0.109
biological adhesion GO:0022610 331 0.109
carboxylic acid biosynthetic process GO:0046394 97 0.108
urogenital system development GO:0001655 65 0.108
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.107
positive regulation of nervous system development GO:0051962 54 0.106
Mouse Rat
cell part morphogenesis GO:0032990 137 0.105
regulation of erk1 and erk2 cascade GO:0070372 99 0.104
vasculature development GO:0001944 181 0.104
Human Mouse
actin filament based process GO:0030029 224 0.103
Human
atp catabolic process GO:0006200 157 0.103
regulation of phosphatase activity GO:0010921 81 0.101
sodium ion transport GO:0006814 61 0.100
organic acid biosynthetic process GO:0016053 97 0.100
adherens junction organization GO:0034332 36 0.100
Fly
regulation of mapk cascade GO:0043408 262 0.099
regulation of transmembrane transporter activity GO:0022898 74 0.097
regulation of cell junction assembly GO:1901888 29 0.097
cell junction assembly GO:0034329 67 0.097
ubiquitin dependent smad protein catabolic process GO:0030579 4 0.096
blood vessel development GO:0001568 172 0.095
Human Mouse
locomotory behavior GO:0007626 1 0.095
regulation of cellular amino acid metabolic process GO:0006521 6 0.095
regulation of ion homeostasis GO:2000021 73 0.095
protein catabolic process GO:0030163 325 0.095
female gamete generation GO:0007292 2 0.094
Fly
endocardial cushion development GO:0003197 3 0.094
positive regulation of endocytosis GO:0045807 42 0.094
intracellular protein transport GO:0006886 270 0.094
negative regulation of sodium ion transmembrane transporter activity GO:2000650 2 0.093
regulation of protein kinase activity GO:0045859 289 0.093
nucleotide catabolic process GO:0009166 408 0.093
epithelial cell development GO:0002064 34 0.092
mitochondrion organization GO:0007005 156 0.092
regulation of nucleotide metabolic process GO:0006140 269 0.091
defense response to virus GO:0051607 71 0.090
actin cytoskeleton organization GO:0030036 207 0.090
Human
positive regulation of kinase activity GO:0033674 204 0.089
autophagy GO:0006914 88 0.088
regulation of isoprenoid metabolic process GO:0019747 1 0.088
receptor metabolic process GO:0043112 81 0.088
inorganic ion transmembrane transport GO:0098660 231 0.088
response to organic cyclic compound GO:0014070 204 0.086
response to transforming growth factor beta GO:0071559 94 0.086
cellular amine metabolic process GO:0044106 41 0.085
convergent extension GO:0060026 1 0.083
monocarboxylic acid biosynthetic process GO:0072330 67 0.083
rap protein signal transduction GO:0032486 7 0.083
epithelium development GO:0060429 227 0.082
cellular potassium ion transport GO:0071804 60 0.082
epidermis development GO:0008544 59 0.082
Worm
regulation of ribosome biogenesis GO:0090069 1 0.081
regulation of cell adhesion GO:0030155 166 0.081
neurological system process GO:0050877 163 0.081
positive regulation of protein kinase activity GO:0045860 190 0.081
negative regulation of secretion GO:0051048 58 0.080
synaptic transmission GO:0007268 61 0.079
Rat
response to abiotic stimulus GO:0009628 336 0.079
oogenesis GO:0048477 2 0.079
Fly
regulation of membrane potential GO:0042391 95 0.079
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.078
cell morphogenesis GO:0000902 296 0.078
regulation of small gtpase mediated signal transduction GO:0051056 156 0.078
metal ion homeostasis GO:0055065 169 0.078
generation of neurons GO:0048699 152 0.077
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.076
synaptic vesicle transport GO:0048489 5 0.076
nuclear transport GO:0051169 179 0.076
immune effector process GO:0002252 159 0.076
potassium ion transmembrane transport GO:0071805 60 0.076
organelle localization GO:0051640 84 0.075
regulation of feeding behavior GO:0060259 3 0.075
regulation of anatomical structure morphogenesis GO:0022603 286 0.075
regulation of lipid biosynthetic process GO:0046890 47 0.075
fatty acid biosynthetic process GO:0006633 46 0.075
response to external biotic stimulus GO:0043207 261 0.075
regulation of dephosphorylation GO:0035303 96 0.075
hemostasis GO:0007599 76 0.074
positive regulation of nucleotide metabolic process GO:0045981 230 0.073
carbohydrate metabolic process GO:0005975 207 0.073
regulation of cofactor metabolic process GO:0051193 3 0.073
regulation of intracellular transport GO:0032386 195 0.072
metal ion transport GO:0030001 272 0.071
guanosine containing compound metabolic process GO:1901068 244 0.071
chromatin assembly or disassembly GO:0006333 78 0.070
regulation of metal ion transport GO:0010959 120 0.070
regulation of locomotion GO:0040012 329 0.070
Mouse
behavior GO:0007610 112 0.069
muscle adaptation GO:0043500 12 0.069
cell activation GO:0001775 213 0.068
viral process GO:0016032 146 0.068
regulation of endocytosis GO:0030100 72 0.067
signal transduction by phosphorylation GO:0023014 297 0.067
establishment of ribosome localization GO:0033753 4 0.066
regulation of cell motility GO:2000145 299 0.066
Mouse
sensory perception of pain GO:0019233 4 0.066
regulation of nervous system development GO:0051960 88 0.066
regulation of protein serine threonine kinase activity GO:0071900 179 0.066
coenzyme biosynthetic process GO:0009108 24 0.066
defense response to other organism GO:0098542 129 0.065
positive regulation of vasculogenesis GO:2001214 1 0.065
Mouse
regulation of establishment of protein localization GO:0070201 242 0.065
membrane organization GO:0061024 292 0.065
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.064
dendrite development GO:0016358 24 0.064
proteasomal protein catabolic process GO:0010498 176 0.064
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.064
purine nucleoside monophosphate catabolic process GO:0009128 158 0.063
modification dependent macromolecule catabolic process GO:0043632 212 0.063
neurogenesis GO:0022008 169 0.062
nucleobase containing compound transport GO:0015931 51 0.062
adherens junction assembly GO:0034333 34 0.062
Fly
regulation of transmembrane transport GO:0034762 139 0.062
positive regulation of rap gtpase activity GO:0032854 8 0.061
ncrna processing GO:0034470 83 0.061
synaptic vesicle localization GO:0097479 5 0.061
defense response GO:0006952 315 0.061
cellular protein catabolic process GO:0044257 261 0.061
protein oligomerization GO:0051259 173 0.060
negative regulation of protein metabolic process GO:0051248 391 0.060
regulation of multi organism process GO:0043900 157 0.060
glycerolipid metabolic process GO:0046486 107 0.060
chromatin organization GO:0006325 351 0.059
small molecule biosynthetic process GO:0044283 157 0.059
regulation of muscle system process GO:0090257 53 0.059
purine nucleoside monophosphate metabolic process GO:0009126 186 0.059
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.058
monocarboxylic acid metabolic process GO:0032787 185 0.058
muscle system process GO:0003012 81 0.058
nucleocytoplasmic transport GO:0006913 176 0.058
regulation of immune effector process GO:0002697 91 0.058
positive regulation of protein catabolic process GO:0045732 75 0.057
ribonucleoside monophosphate metabolic process GO:0009161 187 0.057
amine metabolic process GO:0009308 44 0.057
response to other organism GO:0051707 261 0.057
negative regulation of cell death GO:0060548 345 0.057
establishment of endothelial barrier GO:0061028 16 0.056
single organism carbohydrate metabolic process GO:0044723 193 0.056
cofactor metabolic process GO:0051186 87 0.056
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.056
negative regulation of intracellular signal transduction GO:1902532 183 0.056
post embryonic development GO:0009791 2 0.056
Fly
ribonucleoprotein complex export from nucleus GO:0071426 4 0.056
regulation of cell migration GO:0030334 289 0.056
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.056
regulation of vasculature development GO:1901342 97 0.056
Human Mouse
late endosome to vacuole transport GO:0045324 2 0.056
response to virus GO:0009615 126 0.056
regulation of purine nucleotide catabolic process GO:0033121 205 0.055
negative regulation of neurotransmitter transport GO:0051589 1 0.055
purine nucleoside triphosphate catabolic process GO:0009146 392 0.055
positive regulation of proteolysis GO:0045862 142 0.054
response to uv GO:0009411 73 0.054
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.054
rna transport GO:0050658 39 0.054
regulation of gtpase activity GO:0043087 180 0.054
forebrain generation of neurons GO:0021872 3 0.054
Mouse
smad protein signal transduction GO:0060395 10 0.054
positive regulation of transporter activity GO:0032411 32 0.053
regulation of gtp catabolic process GO:0033124 180 0.053
mrna export from nucleus GO:0006406 29 0.053
neuron projection morphogenesis GO:0048812 50 0.052
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.052
rna processing GO:0006396 255 0.052
negative regulation of programmed cell death GO:0043069 321 0.052
negative regulation of cellular amine metabolic process GO:0033239 3 0.051
heart development GO:0007507 95 0.051
regulation of activin receptor signaling pathway GO:0032925 14 0.051
cellular response to oxygen containing compound GO:1901701 276 0.051
kidney epithelium development GO:0072073 25 0.050
protein polyubiquitination GO:0000209 110 0.050
alcohol metabolic process GO:0006066 114 0.050
nitrogen compound transport GO:0071705 191 0.050
tissue morphogenesis GO:0048729 96 0.049
Fly
regulation of endosome size GO:0051036 3 0.049
regulation of saliva secretion GO:0046877 2 0.049
ribonucleoprotein complex localization GO:0071166 4 0.049
negative regulation of feeding behavior GO:2000252 1 0.048
positive regulation of receptor internalization GO:0002092 12 0.047
sodium ion homeostasis GO:0055078 14 0.047
regulation of cellular response to stress GO:0080135 244 0.047
regulation of body fluid levels GO:0050878 99 0.047
receptor mediated endocytosis GO:0006898 84 0.047
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.047
establishment of vesicle localization GO:0051650 23 0.047
endothelium development GO:0003158 33 0.047
oocyte differentiation GO:0009994 2 0.046
negative regulation of locomotion GO:0040013 118 0.046
negative regulation of catalytic activity GO:0043086 335 0.046
regulation of mrna export from nucleus GO:0010793 3 0.046
response to camp GO:0051591 25 0.046
nuclear export GO:0051168 69 0.046
establishment of protein localization to organelle GO:0072594 172 0.046
regulation of sodium ion transmembrane transport GO:1902305 23 0.046
negative regulation of cellular component organization GO:0051129 235 0.046
determination of adult lifespan GO:0008340 2 0.046
regulation of secretion by cell GO:1903530 177 0.045
response to radiation GO:0009314 151 0.045
negative regulation of protein transport GO:0051224 75 0.045
hindbrain development GO:0030902 3 0.045
regulation of cytoplasmic transport GO:1903649 149 0.044
peptidyl tyrosine phosphorylation GO:0018108 170 0.044
peripheral nervous system development GO:0007422 2 0.044
cellular response to organic cyclic compound GO:0071407 127 0.044
regulation of protein localization GO:0032880 296 0.043
negative regulation of sodium ion transport GO:0010766 3 0.043
regulation of membrane repolarization GO:0060306 16 0.043
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.043
endosomal transport GO:0016197 129 0.042
protein k48 linked ubiquitination GO:0070936 38 0.042
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.042
negative regulation of immune system process GO:0002683 136 0.042
cellular macromolecular complex assembly GO:0034622 324 0.042
modification dependent protein catabolic process GO:0019941 209 0.042
activin receptor signaling pathway GO:0032924 24 0.041
nucleoside monophosphate catabolic process GO:0009125 159 0.041
mitotic cell cycle GO:0000278 326 0.041
regulation of rap protein signal transduction GO:0032487 9 0.041
platelet activation GO:0030168 44 0.041
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.041
response to organophosphorus GO:0046683 41 0.041
cofactor biosynthetic process GO:0051188 31 0.040
neuromuscular junction development GO:0007528 3 0.040
response to metal ion GO:0010038 84 0.040
memory GO:0007613 3 0.040
ubiquitin dependent protein catabolic process GO:0006511 206 0.040
protein autoubiquitination GO:0051865 37 0.040
ribosome localization GO:0033750 4 0.039
intracellular receptor signaling pathway GO:0030522 104 0.039
regulation of fatty acid biosynthetic process GO:0042304 9 0.039
tissue regeneration GO:0042246 3 0.039
regulation of exocytosis GO:0017157 46 0.039
multicellular organismal response to stress GO:0033555 1 0.039
negative regulation of sodium ion transmembrane transport GO:1902306 2 0.039
oocyte development GO:0048599 1 0.039
positive regulation of intracellular transport GO:0032388 104 0.039
stress activated mapk cascade GO:0051403 93 0.039
regulation of nucleocytoplasmic transport GO:0046822 98 0.038
cellular response to abiotic stimulus GO:0071214 117 0.038
single organismal cell cell adhesion GO:0016337 148 0.038
ubiquitin dependent endocytosis GO:0070086 1 0.038
trna processing GO:0008033 23 0.038
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.038
bmp signaling pathway GO:0030509 49 0.038
water homeostasis GO:0030104 14 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.038
positive regulation of transmembrane transport GO:0034764 41 0.038
regulation of protein ubiquitination GO:0031396 95 0.037
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 28 0.037
blastoderm segmentation GO:0007350 2 0.037
protein localization to organelle GO:0033365 280 0.037
single organism cell adhesion GO:0098602 179 0.037
ncrna metabolic process GO:0034660 108 0.037
negative regulation of secretion by cell GO:1903531 52 0.037
regulation of ketone biosynthetic process GO:0010566 7 0.036
glial cell migration GO:0008347 4 0.035
regulation of stress activated mapk cascade GO:0032872 84 0.035
regulation of ras gtpase activity GO:0032318 128 0.035
positive regulation of cell proliferation GO:0008284 301 0.035
blood coagulation GO:0007596 76 0.035
regulation of synaptic transmission GO:0050804 11 0.035
Rat
regulation of potassium ion transport GO:0043266 24 0.035
negative regulation of catabolic process GO:0009895 104 0.035
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.035
vesicle localization GO:0051648 26 0.035
blood circulation GO:0008015 113 0.035
coagulation GO:0050817 78 0.034
transmission of virus GO:0019089 1 0.034
regulation of cytoskeleton organization GO:0051493 177 0.034
Human
steroid metabolic process GO:0008202 94 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.034
positive regulation of ion transmembrane transport GO:0034767 40 0.034
nucleic acid transport GO:0050657 39 0.034
response to purine containing compound GO:0014074 40 0.033
multicellular organismal aging GO:0010259 3 0.033
stress activated protein kinase signaling cascade GO:0031098 94 0.033
regulation of anatomical structure size GO:0090066 101 0.033
regulation of cellular response to growth factor stimulus GO:0090287 76 0.033
signal release GO:0023061 70 0.033
phospholipid metabolic process GO:0006644 99 0.033
protein targeting GO:0006605 187 0.033
ribonucleoprotein complex biogenesis GO:0022613 116 0.033
morphogenesis of embryonic epithelium GO:0016331 4 0.032
Fly
sensory perception of chemical stimulus GO:0007606 38 0.032
mesodermal cell fate commitment GO:0001710 2 0.032
negative regulation of blood pressure GO:0045776 3 0.032
secretion GO:0046903 254 0.032
regulation of sodium ion transport GO:0002028 24 0.032
cell projection assembly GO:0030031 126 0.032
Fly
positive regulation of receptor mediated endocytosis GO:0048260 21 0.032
establishment of nucleus localization GO:0040023 1 0.031
regulation of cellular component movement GO:0051270 334 0.031
Mouse
endodermal cell fate specification GO:0001714 4 0.031
inner ear morphogenesis GO:0042472 4 0.031
regulation of ras protein signal transduction GO:0046578 155 0.031
cation transmembrane transport GO:0098655 238 0.031
cellular response to uv GO:0034644 32 0.031
regulation of cell cycle GO:0051726 393 0.031
secretion by cell GO:0032940 226 0.030
regulation of proteolysis GO:0030162 293 0.030
plasma membrane organization GO:0007009 115 0.030
regulation of ion transport GO:0043269 189 0.030
vasculogenesis GO:0001570 8 0.030
Mouse
chemical homeostasis GO:0048878 306 0.030
dendrite morphogenesis GO:0048813 14 0.030
negative regulation of ion transmembrane transport GO:0034766 26 0.029
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.029
reactive oxygen species metabolic process GO:0072593 75 0.029
positive regulation of synaptic transmission GO:0050806 4 0.029
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.029
positive regulation of ion transport GO:0043270 87 0.029
nucleoside monophosphate metabolic process GO:0009123 191 0.029
endodermal cell fate commitment GO:0001711 4 0.028
positive regulation of heart growth GO:0060421 2 0.028
cellular protein complex assembly GO:0043623 188 0.028
peptidyl serine modification GO:0018209 106 0.028
heart morphogenesis GO:0003007 48 0.028
somatic muscle development GO:0007525 1 0.028
regulation of ion transmembrane transporter activity GO:0032412 72 0.028
endothelial cell differentiation GO:0045446 26 0.028
negative regulation of proteolysis GO:0045861 132 0.028
establishment of protein localization to membrane GO:0090150 121 0.027
isoprenoid metabolic process GO:0006720 39 0.027
progesterone receptor signaling pathway GO:0050847 3 0.027
quinone metabolic process GO:1901661 18 0.027
positive regulation of cell adhesion GO:0045785 84 0.027
nuclear division GO:0000280 128 0.027
regulation of coenzyme metabolic process GO:0051196 3 0.027
negative regulation of potassium ion transmembrane transporter activity GO:1901017 3 0.027
establishment or maintenance of cell polarity GO:0007163 31 0.027
negative regulation of protein modification process GO:0031400 200 0.027
regeneration GO:0031099 4 0.026
regulation of jnk cascade GO:0046328 73 0.026
regulation of dendrite morphogenesis GO:0048814 11 0.026
stem cell development GO:0048864 69 0.026
Fly
mrna transport GO:0051028 30 0.026
jnk cascade GO:0007254 80 0.026
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 1 0.026
response to wounding GO:0009611 168 0.026
ketone biosynthetic process GO:0042181 17 0.026
stem cell division GO:0017145 2 0.026
negative regulation of defense response GO:0031348 47 0.026
glomerular visceral epithelial cell differentiation GO:0072112 4 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
cell fate determination GO:0001709 3 0.026
response to light stimulus GO:0009416 87 0.026
reactive oxygen species biosynthetic process GO:1903409 4 0.026

RAPGEF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
respiratory system disease DOID:1579 14 0.071
lower respiratory tract disease DOID:0050161 13 0.071
urinary system disease DOID:18 40 0.032
kidney disease DOID:557 36 0.026