IMP

Process View

Homo sapiens

26 genes annotated in human

Multi-species View

vesicle localization

GO:0051648

Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "vesicle localization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "vesicle localization" (in gray)

Name	Description	Probability	Func Analog Organism
DNM2	dynamin 2	0.981	Fly
ITSN1	intersectin 1 (SH3 domain protein)	0.920	Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.723
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.703
SNAP25	synaptosomal-associated protein, 25kDa	0.703	Fly
DNM1	dynamin 1	0.647	Fly
DTNBP1	dystrobrevin binding protein 1	0.639
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.614
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.541	Mouse
LRRK2	leucine-rich repeat kinase 2	0.455
HTT	huntingtin	0.438
NUMB	numb homolog (Drosophila)	0.357
APP	amyloid beta (A4) precursor protein	0.335
RAB1A	RAB1A, member RAS oncogene family	0.283
AMPH	amphiphysin	0.280	Mouse
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.263
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.246	Rat
TMED2	transmembrane emp24 domain trafficking protein 2	0.242
VIPAR	VPS33B interacting protein, apical-basolateral polarity regulator	0.221
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.215
GSK3B	glycogen synthase kinase 3 beta	0.207
OCRL	oculocerebrorenal syndrome of Lowe	0.201
SH3GL3	SH3-domain GRB2-like 3	0.171	Fly
IQGAP1	IQ motif containing GTPase activating protein 1	0.166
SNX9	sorting nexin 9	0.158
VIM	vimentin	0.152
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.151
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.148	Mouse
BLOC1S2	biogenesis of lysosomal organelles complex-1, subunit 2	0.132
ARF6	ADP-ribosylation factor 6	0.124
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.124
ARRB1	arrestin, beta 1	0.124
SH3KBP1	SH3-domain kinase binding protein 1	0.120
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.110	Fly
PSEN1	presenilin 1	0.110	Mouse
KIF5B	kinesin family member 5B	0.110	Mouse Rat Worm
RAB6A	RAB6A, member RAS oncogene family	0.108
DAAM1	dishevelled associated activator of morphogenesis 1	0.103
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.101	Mouse Worm
STX5	syntaxin 5	0.092
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.086	Fly
RBM8A	RNA binding motif protein 8A	0.082
GOLGA2	golgin A2	0.080
MAP2K4	mitogen-activated protein kinase kinase 4	0.073
CSNK1A1	casein kinase 1, alpha 1	0.070
SYNJ1	synaptojanin 1	0.070	Mouse Fly
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.067
MED31	mediator complex subunit 31	0.067
ARF4	ADP-ribosylation factor 4	0.065
RAB7A	RAB7A, member RAS oncogene family	0.065
OPTN	optineurin	0.065
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.061	Mouse
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.060
TOR1A	torsin family 1, member A (torsin A)	0.060
KLHL2	kelch-like 2, Mayven (Drosophila)	0.058	Human
RAB2A	RAB2A, member RAS oncogene family	0.056
DAPK1	death-associated protein kinase 1	0.055
MAP2K7	mitogen-activated protein kinase kinase 7	0.055
CREBBP	CREB binding protein	0.055
GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	0.054
APC	adenomatous polyposis coli	0.054
MAPK1	mitogen-activated protein kinase 1	0.053
SNAP23	synaptosomal-associated protein, 23kDa	0.052	Fly
PICALM	phosphatidylinositol binding clathrin assembly protein	0.050	Mouse Worm Fly
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.049
MAPT	microtubule-associated protein tau	0.048
CLASP1	cytoplasmic linker associated protein 1	0.048
RAB5A	RAB5A, member RAS oncogene family	0.048
STX1A	syntaxin 1A (brain)	0.046	Mouse Rat Fly
AGTPBP1	ATP/GTP binding protein 1	0.045
SURF4	surfeit 4	0.043
NCF1	neutrophil cytosolic factor 1	0.042
CLIP1	CAP-GLY domain containing linker protein 1	0.040
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.039
DPYSL4	dihydropyrimidinase-like 4	0.039
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.039	Fly
RAP1GAP	RAP1 GTPase activating protein	0.039
BTRC	beta-transducin repeat containing	0.038
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.038
KIAA1377	KIAA1377	0.038
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.035
HIP1	huntingtin interacting protein 1	0.035
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.034
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.033	Human
EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	0.033
FGF1	fibroblast growth factor 1 (acidic)	0.033
SEC24D	SEC24 family, member D (S. cerevisiae)	0.032
MAPK14	mitogen-activated protein kinase 14	0.032
MAPK9	mitogen-activated protein kinase 9	0.032	Worm
SH3GL1	SH3-domain GRB2-like 1	0.032	Fly
SOS1	son of sevenless homolog 1 (Drosophila)	0.031
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.031	Mouse
FNBP1	formin binding protein 1	0.031	Human
SH3GL2	SH3-domain GRB2-like 2	0.030	Mouse Fly
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.030
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.029
ARRB2	arrestin, beta 2	0.029
RAB14	RAB14, member RAS oncogene family	0.029
SYT1	synaptotagmin I	0.029	Mouse Fly
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.029
CTNND1	catenin (cadherin-associated protein), delta 1	0.028
SPOP	speckle-type POZ protein	0.028
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.027
WNK4	WNK lysine deficient protein kinase 4	0.027
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.026	Mouse
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.026
FGF10	fibroblast growth factor 10	0.026
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.026
MAP4	microtubule-associated protein 4	0.026
DLG4	discs, large homolog 4 (Drosophila)	0.025	Mouse
STX4	syntaxin 4	0.025	Rat
KLHL12	kelch-like 12 (Drosophila)	0.024
BTBD10	BTB (POZ) domain containing 10	0.024
BBS9	Bardet-Biedl syndrome 9	0.024
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.024
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.023
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.023
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.023
RABIF	RAB interacting factor	0.023
SQSTM1	sequestosome 1	0.022
GRB2	growth factor receptor-bound protein 2	0.022
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.022
WDYHV1	WDYHV motif containing 1	0.022
NSF	N-ethylmaleimide-sensitive factor	0.021	Fly
BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1	0.021
RAB10	RAB10, member RAS oncogene family	0.021
AGFG1	ArfGAP with FG repeats 1	0.021
XPO6	exportin 6	0.021
PPP5C	protein phosphatase 5, catalytic subunit	0.020
TM9SF2	transmembrane 9 superfamily member 2	0.020
SEC24C	SEC24 family, member C (S. cerevisiae)	0.020
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.020
MTF1	metal-regulatory transcription factor 1	0.020
SH3BP4	SH3-domain binding protein 4	0.020
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.020
AP1B1	adaptor-related protein complex 1, beta 1 subunit	0.019
TJP2	tight junction protein 2 (zona occludens 2)	0.019
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.019
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.019
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.019
ANXA7	annexin A7	0.019
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.019
MAST1	microtubule associated serine/threonine kinase 1	0.019
PRKCA	protein kinase C, alpha	0.019
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.019
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.019
DCTN1	dynactin 1	0.018	Mouse
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.018
TOR1AIP2	torsin A interacting protein 2	0.018
RABAC1	Rab acceptor 1 (prenylated)	0.018
CALU	calumenin	0.018
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.018
MYO1E	myosin IE	0.018
RUSC2	RUN and SH3 domain containing 2	0.017
TMED7	transmembrane emp24 protein transport domain containing 7	0.017
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.017
CLPTM1	cleft lip and palate associated transmembrane protein 1	0.017
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.017
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.017
STX12	syntaxin 12	0.017
WASL	Wiskott-Aldrich syndrome-like	0.016	Rat
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.016
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.016
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.016
DPP3	dipeptidyl-peptidase 3	0.016
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.016
JUP	junction plakoglobin	0.016
FAM190B	family with sequence similarity 190, member B	0.016
RPN2	ribophorin II	0.015
TRAM1	translocation associated membrane protein 1	0.015
CUL3	cullin 3	0.015
BSN	bassoon (presynaptic cytomatrix protein)	0.015
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.015
DUSP3	dual specificity phosphatase 3	0.015
ADAM9	ADAM metallopeptidase domain 9	0.015
CADM4	cell adhesion molecule 4	0.015
NCSTN	nicastrin	0.015
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.015
ARCN1	archain 1	0.015
ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	0.015
CLIC4	chloride intracellular channel 4	0.014
VAMP7	vesicle-associated membrane protein 7	0.014
SDF2L1	stromal cell-derived factor 2-like 1	0.014
APLP1	amyloid beta (A4) precursor-like protein 1	0.014
CORO1C	coronin, actin binding protein, 1C	0.014
EEA1	early endosome antigen 1	0.014
PRMT6	protein arginine methyltransferase 6	0.014
PIAS4	protein inhibitor of activated STAT, 4	0.014
CTTN	cortactin	0.014
AP3B1	adaptor-related protein complex 3, beta 1 subunit	0.014	Mouse
FNDC3B	fibronectin type III domain containing 3B	0.014
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.014
LIN7A	lin-7 homolog A (C. elegans)	0.014	Mouse
NUP54	nucleoporin 54kDa	0.014
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.013
ZDHHC17	zinc finger, DHHC-type containing 17	0.013
GOLGB1	golgin B1	0.013
MYO5A	myosin VA (heavy chain 12, myoxin)	0.013
EPS8	epidermal growth factor receptor pathway substrate 8	0.013
ERC2	ELKS/RAB6-interacting/CAST family member 2	0.013
SSFA2	sperm specific antigen 2	0.013
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.013
FASLG	Fas ligand (TNF superfamily, member 6)	0.013
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.013
BAG1	BCL2-associated athanogene	0.013
GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	0.013
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.013
GDI2	GDP dissociation inhibitor 2	0.013
RUNDC3B	RUN domain containing 3B	0.013
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.013
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.013
TAOK1	TAO kinase 1	0.012
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.012
DDN	dendrin	0.012
SERP1	stress-associated endoplasmic reticulum protein 1	0.012
TOR1B	torsin family 1, member B (torsin B)	0.012	Human
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.012
CABLES1	Cdk5 and Abl enzyme substrate 1	0.012
CRMP1	collapsin response mediator protein 1	0.012
DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	0.012	Rat
MAP1B	microtubule-associated protein 1B	0.012
PFN2	profilin 2	0.012	Mouse
NIN	ninein (GSK3B interacting protein)	0.012
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.012
ACTL6B	actin-like 6B	0.012
MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	0.012
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
RPH3A	rabphilin 3A homolog (mouse)	0.011
ARF5	ADP-ribosylation factor 5	0.011
SPAG9	sperm associated antigen 9	0.011	Worm
AP3S1	adaptor-related protein complex 3, sigma 1 subunit	0.011	Mouse
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.011
SEC13	SEC13 homolog (S. cerevisiae)	0.011
PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	0.011
MEA1	male-enhanced antigen 1	0.011
YAP1	Yes-associated protein 1	0.011
KLHL20	kelch-like 20 (Drosophila)	0.011	Human
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.011
SNX2	sorting nexin 2	0.011
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.011	Mouse
COPA	coatomer protein complex, subunit alpha	0.011
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.011
MAP7D1	MAP7 domain containing 1	0.011
RUNDC3A	RUN domain containing 3A	0.011
EPN1	epsin 1	0.011
RHOA	ras homolog gene family, member A	0.011
PRKCE	protein kinase C, epsilon	0.011	Worm
ADAM10	ADAM metallopeptidase domain 10	0.011
RPN1	ribophorin I	0.011
REEP5	receptor accessory protein 5	0.011
EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.011
TOR1AIP1	torsin A interacting protein 1	0.010
SDC2	syndecan 2	0.010
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.010	Mouse
SPRY2	sprouty homolog 2 (Drosophila)	0.010
MBIP	MAP3K12 binding inhibitory protein 1	0.010
QKI	quaking homolog, KH domain RNA binding (mouse)	0.010
STRN3	striatin, calmodulin binding protein 3	0.010
GIPC1	GIPC PDZ domain containing family, member 1	0.010
NPTN	neuroplastin	0.010
DSP	desmoplakin	0.010
ANKRD11	ankyrin repeat domain 11	0.010
CNTF	ciliary neurotrophic factor	0.010
EMD	emerin	0.010