Homo sapiens

114 known processes

SUV39H1

suppressor of variegation 3-9 homolog 1 (Drosophila)

(Aliases: SUV39H,MG44,KMT1A)

SUV39H1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin modification GO:0016568 298 0.992
covalent chromatin modification GO:0016569 254 0.988
positive regulation of collateral sprouting GO:0048672 2 0.984
macromolecule methylation GO:0043414 97 0.982
chromatin organization GO:0006325 351 0.982
histone methylation GO:0016571 60 0.968
protein alkylation GO:0008213 74 0.958
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.944
gene silencing GO:0016458 49 0.915
chromatin silencing at rdna GO:0000183 5 0.906
positive regulation of hormone biosynthetic process GO:0046886 4 0.872
histone lysine methylation GO:0034968 50 0.829
protein demethylation GO:0006482 17 0.823
histone h3 k9 modification GO:0061647 11 0.660
histone modification GO:0016570 251 0.624
methylation GO:0032259 106 0.559
chromatin silencing GO:0006342 12 0.549
dna hypermethylation GO:0044026 1 0.547
mitotic cell cycle GO:0000278 326 0.546
negative regulation of gene expression epigenetic GO:0045814 19 0.496
peptidyl lysine dimethylation GO:0018027 3 0.425
Mouse
histone demethylation GO:0016577 15 0.406
post embryonic development GO:0009791 2 0.400
chromatin assembly GO:0031497 61 0.374
regulation of cell cycle GO:0051726 393 0.353
t cell differentiation in thymus GO:0033077 4 0.304
positive regulation of cell proliferation GO:0008284 301 0.296
histone h3 k9 demethylation GO:0033169 7 0.281
chromatin assembly or disassembly GO:0006333 78 0.252
Human
dna conformation change GO:0071103 113 0.251
peptidyl lysine modification GO:0018205 144 0.242
regulation of cell cycle arrest GO:0071156 36 0.239
nuclear division GO:0000280 128 0.232
negative regulation of chromatin modification GO:1903309 21 0.229
positive regulation of histone modification GO:0031058 29 0.225
pituitary gland development GO:0021983 2 0.220
regulation of histone methylation GO:0031060 16 0.218
regulation of histone h3 k27 methylation GO:0061085 4 0.210
head development GO:0060322 108 0.206
mitotic sister chromatid segregation GO:0000070 53 0.205
post embryonic organ development GO:0048569 1 0.192
positive regulation of cell differentiation GO:0045597 211 0.188
regulation of chromosome organization GO:0033044 103 0.185
chromosome segregation GO:0007059 114 0.179
positive regulation of cellular component organization GO:0051130 376 0.177
brain development GO:0007420 97 0.172
nervous system development GO:0007399 293 0.169
regulation of anatomical structure size GO:0090066 101 0.163
female gamete generation GO:0007292 2 0.161
positive regulation of neural precursor cell proliferation GO:2000179 2 0.155
demethylation GO:0070988 37 0.154
regulation of nucleocytoplasmic transport GO:0046822 98 0.151
establishment of protein localization to organelle GO:0072594 172 0.145
negative regulation of cellular component organization GO:0051129 235 0.144
positive regulation of developmental process GO:0051094 314 0.139
regulation of chromatin organization GO:1902275 56 0.136
protein dealkylation GO:0008214 17 0.132
positive regulation of organelle organization GO:0010638 195 0.131
negative regulation of programmed cell death GO:0043069 321 0.130
organelle fission GO:0048285 149 0.129
dna dependent dna replication GO:0006261 44 0.122
cellular macromolecular complex assembly GO:0034622 324 0.121
methylation dependent chromatin silencing GO:0006346 3 0.118
positive regulation of transcription during mitosis GO:0045897 2 0.115
protein localization to nucleus GO:0034504 136 0.114
negative regulation of cellular protein metabolic process GO:0032269 353 0.111
regulation of gene silencing GO:0060968 24 0.109
mitotic cell cycle process GO:1903047 286 0.104
positive regulation of chromatin modification GO:1903310 30 0.103
cell development GO:0048468 328 0.102
camera type eye development GO:0043010 25 0.100
Zebrafish
negative regulation of histone methylation GO:0031061 6 0.097
negative regulation of histone h3 k9 methylation GO:0051573 3 0.097
regulation of growth GO:0040008 165 0.096
positive regulation of dna metabolic process GO:0051054 73 0.094
response to fungus GO:0009620 4 0.094
v d j recombination GO:0033151 3 0.090
dna replication independent nucleosome assembly GO:0006336 27 0.085
cardiovascular system development GO:0072358 262 0.085
positive regulation of chromosome organization GO:2001252 41 0.082
cell projection organization GO:0030030 252 0.082
double strand break repair GO:0006302 101 0.081
cellular response to decreased oxygen levels GO:0036294 51 0.079
regulation of cell cycle process GO:0010564 266 0.079
forebrain neuron differentiation GO:0021879 3 0.079
male meiosis GO:0007140 1 0.073
protein import GO:0017038 130 0.069
reproductive process GO:0022414 106 0.069
hematopoietic or lymphoid organ development GO:0048534 186 0.068
regulation of protein localization to nucleus GO:1900180 85 0.068
positive regulation of cell cycle process GO:0090068 106 0.067
regulation of cell differentiation GO:0045595 393 0.067
protein import into nucleus GO:0006606 104 0.067
atp catabolic process GO:0006200 157 0.065
negative regulation of protein metabolic process GO:0051248 391 0.064
dna replication GO:0006260 116 0.064
regulation of cellular component size GO:0032535 82 0.061
t cell selection GO:0045058 4 0.061
sensory organ development GO:0007423 52 0.060
Zebrafish
positive regulation of intracellular protein transport GO:0090316 76 0.060
multicellular organismal aging GO:0010259 3 0.059
regulation of protein targeting GO:1903533 91 0.058
nucleosome assembly GO:0006334 50 0.058
transcription factor import into nucleus GO:0042991 40 0.056
single organism nuclear import GO:1902593 104 0.056
neuron differentiation GO:0030182 138 0.056
neurogenesis GO:0022008 169 0.056
negative regulation of apoptotic process GO:0043066 316 0.055
positive regulation of cytoplasmic transport GO:1903651 82 0.054
eye development GO:0001654 42 0.053
Zebrafish
ribonucleoside monophosphate metabolic process GO:0009161 187 0.052
protein targeting to nucleus GO:0044744 104 0.051
histone h3 k4 demethylation GO:0034720 4 0.049
regulation of transcription factor import into nucleus GO:0042990 39 0.049
protein methylation GO:0006479 74 0.047
protein sumoylation GO:0016925 25 0.047
growth GO:0040007 202 0.047
mitotic cell cycle phase transition GO:0044772 162 0.046
response to hypoxia GO:0001666 96 0.046
negative regulation of organelle organization GO:0010639 126 0.045
protein modification by small protein conjugation GO:0032446 342 0.045
positive regulation of hematopoietic progenitor cell differentiation GO:1901534 5 0.045
negative regulation of mitotic cell cycle GO:0045930 102 0.044
neuron fate commitment GO:0048663 2 0.044
nucleosome organization GO:0034728 66 0.044
negative regulation of cell cycle phase transition GO:1901988 89 0.044
regulation of cell growth GO:0001558 135 0.044
cell part morphogenesis GO:0032990 137 0.043
regulation of protein transport GO:0051223 213 0.042
oogenesis GO:0048477 2 0.042
negative regulation of cell death GO:0060548 345 0.041
negative regulation of developmental process GO:0051093 247 0.041
purine containing compound catabolic process GO:0072523 411 0.041
response to oxygen containing compound GO:1901700 369 0.041
regulation of mitotic cell cycle GO:0007346 189 0.039
regulation of histone h3 k4 methylation GO:0051569 10 0.039
regulation of dna replication GO:0006275 68 0.038
positive regulation of transcription factor import into nucleus GO:0042993 25 0.038
cellular response to endogenous stimulus GO:0071495 336 0.037
mitotic sister chromatid cohesion GO:0007064 12 0.037
nuclear import GO:0051170 106 0.037
regulation of protein import into nucleus GO:0042306 78 0.036
protein targeting GO:0006605 187 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
regulation of gene expression epigenetic GO:0040029 73 0.036
negative regulation of cell cycle GO:0045786 193 0.036
regulation of cell development GO:0060284 161 0.036
forebrain generation of neurons GO:0021872 3 0.035
organelle assembly GO:0070925 176 0.035
negative regulation of histone modification GO:0031057 19 0.035
positive regulation of intracellular transport GO:0032388 104 0.035
positive regulation of protein import into nucleus GO:0042307 46 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.034
leukocyte differentiation GO:0002521 98 0.033
histone h3 k4 methylation GO:0051568 27 0.033
embryo development GO:0009790 123 0.033
nuclear transport GO:0051169 179 0.033
regulation of intracellular protein transport GO:0033157 123 0.033
single organism cellular localization GO:1902580 332 0.033
positive regulation of nervous system development GO:0051962 54 0.032
response to inorganic substance GO:0010035 127 0.032
lymphocyte differentiation GO:0030098 35 0.032
neuron development GO:0048666 113 0.032
negative regulation of cell differentiation GO:0045596 171 0.032
purine nucleoside catabolic process GO:0006152 398 0.031
positive regulation of cell development GO:0010720 92 0.031
response to purine containing compound GO:0014074 40 0.031
thymus development GO:0048538 3 0.031
purine nucleoside monophosphate catabolic process GO:0009128 158 0.031
regulation of histone modification GO:0031056 47 0.031
intracellular protein transport GO:0006886 270 0.031
gland development GO:0048732 48 0.031
regulation of neuron projection development GO:0010975 57 0.031
dna replication dependent nucleosome organization GO:0034723 32 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.030
single organism reproductive process GO:0044702 98 0.029
regulation of histone h3 k9 methylation GO:0051570 6 0.029
protein localization to organelle GO:0033365 280 0.029
t cell differentiation GO:0030217 29 0.029
central nervous system development GO:0007417 123 0.029
positive regulation of phosphorylation GO:0042327 394 0.028
regulation of protein localization GO:0032880 296 0.028
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.028
circulatory system development GO:0072359 262 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
positive regulation of growth GO:0045927 58 0.027
vesicle mediated transport GO:0016192 371 0.027
positive regulation of cell cycle GO:0045787 140 0.027
epidermal cell differentiation GO:0009913 45 0.027
protein dna complex assembly GO:0065004 64 0.026
sister chromatid segregation GO:0000819 54 0.026
regulation of collateral sprouting GO:0048670 2 0.026
membrane organization GO:0061024 292 0.025
cell morphogenesis GO:0000902 296 0.025
purine nucleoside monophosphate metabolic process GO:0009126 186 0.025
cellular response to organic cyclic compound GO:0071407 127 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
positive regulation of protein transport GO:0051222 135 0.025
neuron projection development GO:0031175 106 0.024
cellular component morphogenesis GO:0032989 314 0.024
positive regulation of histone methylation GO:0031062 12 0.024
negative regulation of transcription factor import into nucleus GO:0042992 17 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
mitotic cell cycle checkpoint GO:0007093 68 0.024
regulation of neurogenesis GO:0050767 82 0.023
meiotic chromosome segregation GO:0045132 4 0.023
positive regulation of immune system process GO:0002684 283 0.023
negative regulation of cell cycle process GO:0010948 121 0.023
g2 m transition of mitotic cell cycle GO:0000086 41 0.023
response to organic cyclic compound GO:0014070 204 0.022
regulation of transcription by chromatin organization GO:0034401 1 0.022
response to abiotic stimulus GO:0009628 336 0.022
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.022
cellular response to oxygen levels GO:0071453 55 0.022
positive regulation of neurogenesis GO:0050769 49 0.021
organophosphate catabolic process GO:0046434 430 0.021
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.021
ribonucleoside catabolic process GO:0042454 406 0.021
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.021
oocyte differentiation GO:0009994 2 0.021
defense response to fungus GO:0050832 4 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.020
regulation of lipid metabolic process GO:0019216 96 0.020
negative regulation of phosphate metabolic process GO:0045936 267 0.020
positive regulation of protein catabolic process GO:0045732 75 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
dna replication independent nucleosome organization GO:0034724 27 0.020
purine ribonucleotide catabolic process GO:0009154 404 0.020
positive regulation of transferase activity GO:0051347 227 0.020
immune system development GO:0002520 195 0.020
negative regulation of chromosome organization GO:2001251 48 0.020
cell growth GO:0016049 160 0.020
microtubule cytoskeleton organization GO:0000226 176 0.020
mitotic dna damage checkpoint GO:0044773 28 0.019
response to ionizing radiation GO:0010212 65 0.019
epidermis development GO:0008544 59 0.019
negative regulation of cell proliferation GO:0008285 228 0.019
muscle cell differentiation GO:0042692 63 0.019
negative regulation of developmental growth GO:0048640 10 0.019
dna methylation or demethylation GO:0044728 19 0.019
regulation of cellular response to stress GO:0080135 244 0.019
response to nitrogen compound GO:1901698 184 0.019
Rat
regulation of intracellular transport GO:0032386 195 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
hormone biosynthetic process GO:0042446 22 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
maintenance of protein location GO:0045185 57 0.018
striated muscle myosin thick filament assembly GO:0071688 2 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
nucleoside triphosphate catabolic process GO:0009143 394 0.018
positive regulation of cell projection organization GO:0031346 64 0.018
positive regulation of protein kinase activity GO:0045860 190 0.018
posttranscriptional regulation of gene expression GO:0010608 213 0.018
forebrain development GO:0030900 26 0.018
negative regulation of growth GO:0045926 97 0.018
response to organophosphorus GO:0046683 41 0.018
signal transduction by p53 class mediator GO:0072331 72 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.017
nucleobase metabolic process GO:0009112 8 0.017
negative regulation of collateral sprouting GO:0048671 1 0.017
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.017
positive regulation of cell growth GO:0030307 48 0.017
positive regulation of protein localization to nucleus GO:1900182 48 0.017
negative regulation of axonogenesis GO:0050771 4 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
nucleotide catabolic process GO:0009166 408 0.017
cellular response to camp GO:0071320 21 0.017
regulation of nervous system development GO:0051960 88 0.017
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.017
anatomical structure formation involved in morphogenesis GO:0048646 284 0.017
meiosis i GO:0007127 4 0.017
regulation of epithelial cell proliferation GO:0050678 113 0.016
myosin filament assembly GO:0031034 2 0.016
protein dna complex subunit organization GO:0071824 80 0.016
response to oxygen levels GO:0070482 100 0.016
cellular response to lipid GO:0071396 127 0.016
regulation of neuron differentiation GO:0045664 70 0.015
response to biotic stimulus GO:0009607 276 0.015
chemotaxis GO:0006935 157 0.015
spermatid development GO:0007286 4 0.015
spermatid differentiation GO:0048515 4 0.015
developmental growth GO:0048589 48 0.015
lymphocyte activation GO:0046649 133 0.015
cellular component assembly involved in morphogenesis GO:0010927 73 0.015
regulation of homeostatic process GO:0032844 121 0.015
negative regulation of cell development GO:0010721 48 0.015
response to steroid hormone GO:0048545 80 0.014
response to radiation GO:0009314 151 0.014
regulation of transcription during mitosis GO:0045896 2 0.014
regulation of cell cycle phase transition GO:1901987 126 0.014
positive regulation of cell death GO:0010942 263 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.014
purine nucleoside triphosphate metabolic process GO:0009144 412 0.014
sister chromatid cohesion GO:0007062 24 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
regulation of cell size GO:0008361 19 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
positive regulation of developmental growth GO:0048639 16 0.014
keratinocyte differentiation GO:0030216 36 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
maintenance of location GO:0051235 112 0.014
digestive tract morphogenesis GO:0048546 56 0.014
epithelial cell development GO:0002064 34 0.014
response to external biotic stimulus GO:0043207 261 0.013
cell fate commitment GO:0045165 27 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
cell division GO:0051301 168 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 24 0.013
ribonucleoside monophosphate catabolic process GO:0009158 158 0.013
mitotic nuclear division GO:0007067 119 0.013
cellular response to organonitrogen compound GO:0071417 124 0.013
oocyte maturation GO:0001556 1 0.013
cell cycle phase transition GO:0044770 173 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
cofactor metabolic process GO:0051186 87 0.013
generation of neurons GO:0048699 152 0.013
embryonic morphogenesis GO:0048598 85 0.013
mitotic dna integrity checkpoint GO:0044774 30 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.012
oocyte development GO:0048599 1 0.012
cell cycle g2 m phase transition GO:0044839 43 0.012
endocytosis GO:0006897 159 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
regeneration GO:0031099 4 0.012
negative regulation of nervous system development GO:0051961 28 0.012
nucleocytoplasmic transport GO:0006913 176 0.012
response to metal ion GO:0010038 84 0.011
regulation of mapk cascade GO:0043408 262 0.011
negative regulation of neurogenesis GO:0050768 26 0.011
maintenance of protein location in cell GO:0032507 56 0.011
positive regulation of transport GO:0051050 336 0.011
stress activated mapk cascade GO:0051403 93 0.011
defense response GO:0006952 315 0.011
endomembrane system organization GO:0010256 196 0.011
regulation of circadian rhythm GO:0042752 11 0.011
Mouse
actin filament based process GO:0030029 224 0.011
heart development GO:0007507 95 0.011
positive regulation of cell cycle arrest GO:0071158 23 0.011
reproductive structure development GO:0048608 55 0.011
regulation of chromatin modification GO:1903308 51 0.011
protein oligomerization GO:0051259 173 0.011
cell fate determination GO:0001709 3 0.011
double strand break repair via nonhomologous end joining GO:0006303 10 0.011
amine metabolic process GO:0009308 44 0.011
regulation of cellular amine metabolic process GO:0033238 11 0.011
reproduction GO:0000003 63 0.011
muscle structure development GO:0061061 98 0.011
cellular protein catabolic process GO:0044257 261 0.011
compound eye development GO:0048749 1 0.011
cerebral cortex development GO:0021987 10 0.010
signal transduction in response to dna damage GO:0042770 57 0.010
regulation of hormone metabolic process GO:0032350 14 0.010
positive regulation of catabolic process GO:0009896 310 0.010
granulocyte differentiation GO:0030851 16 0.010
telencephalon development GO:0021537 17 0.010
dephosphorylation GO:0016311 209 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
subpallium development GO:0021544 2 0.010
myosin filament organization GO:0031033 2 0.010
neuron projection morphogenesis GO:0048812 50 0.010

SUV39H1 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.033
disease of cellular proliferation DOID:14566 174 0.033
organ system cancer DOID:0050686 164 0.033
gastrointestinal system cancer DOID:3119 52 0.013