|
positive regulation of immune response
|
GO:0050778 |
159 |
1.000
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
1.000
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
1.000
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.999
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.999
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.998
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.998
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.997
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.997
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.995
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.995
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.995
|
|
|
defense response
|
GO:0006952 |
315 |
0.995
|
Mouse |
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.993
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.993
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.993
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.993
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.992
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.990
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.990
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.989
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.988
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.987
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.986
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.985
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.984
|
Mouse |
|
response to bacterium
|
GO:0009617 |
144 |
0.979
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.977
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.977
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.977
|
Mouse |
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.971
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.970
|
|
|
cell activation
|
GO:0001775 |
213 |
0.970
|
Mouse |
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.968
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.968
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.965
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.962
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.959
|
Mouse |
|
immune system development
|
GO:0002520 |
195 |
0.959
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.954
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.952
|
Mouse |
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.949
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.943
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.924
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.921
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.920
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.908
|
Mouse |
|
immune response
|
GO:0006955 |
307 |
0.898
|
Mouse |
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.896
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.896
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.890
|
Mouse |
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.889
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.889
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.888
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.878
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.878
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.878
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
25 |
0.873
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.869
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.868
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.867
|
Mouse |
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.862
|
Mouse |
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.862
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.856
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
17 |
0.851
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.847
|
Mouse |
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.840
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
20 |
0.830
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.827
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.818
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.812
|
Mouse |
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.799
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.761
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.759
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.758
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.749
|
Mouse |
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.741
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.734
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.724
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.712
|
|
|
chemokine metabolic process
|
GO:0050755 |
4 |
0.709
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.708
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.705
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.700
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.697
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.697
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.692
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.685
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.677
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.675
|
|
|
positive regulation of nf kappab import into nucleus
|
GO:0042346 |
13 |
0.672
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.670
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.670
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.666
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.661
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.658
|
Mouse |
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.654
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.634
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.626
|
|
|
positive regulation of smooth muscle cell proliferation
|
GO:0048661 |
14 |
0.607
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.598
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.594
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.593
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.593
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.588
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.572
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.555
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.554
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.553
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.548
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.541
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.540
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.538
|
Mouse |
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.535
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.529
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.527
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.518
|
|
|
regulation of granzyme b production
|
GO:0071661 |
1 |
0.506
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.503
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
4 |
0.498
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.488
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.486
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
22 |
0.484
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.480
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.480
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.470
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
3 |
0.461
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.460
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.459
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.451
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.451
|
Mouse |
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.450
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.446
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.445
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.442
|
Human |
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.427
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.424
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.419
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.418
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.417
|
|
|
response to virus
|
GO:0009615 |
126 |
0.415
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.415
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
4 |
0.411
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.409
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.409
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.405
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.401
|
Mouse |
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.396
|
|
|
fat soluble vitamin metabolic process
|
GO:0006775 |
19 |
0.395
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.388
|
Mouse |
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.385
|
|
|
vitamin d metabolic process
|
GO:0042359 |
10 |
0.380
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.371
|
Mouse |
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.368
|
Mouse |
|
regulation of heterotypic cell cell adhesion
|
GO:0034114 |
14 |
0.367
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.365
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.361
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.355
|
Mouse |
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.351
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.349
|
Mouse |
|
regulation of interleukin 6 production
|
GO:0032675 |
37 |
0.348
|
Mouse |
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.348
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.347
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.346
|
|
|
cd40 signaling pathway
|
GO:0023035 |
3 |
0.344
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.342
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.340
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.340
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.332
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.321
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.318
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.315
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.309
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.308
|
|
|
interleukin 2 production
|
GO:0032623 |
20 |
0.306
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.302
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.301
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.297
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.292
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.291
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.290
|
Human |
|
positive regulation of transport
|
GO:0051050 |
336 |
0.288
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.287
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.280
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.274
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.274
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.273
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.268
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.268
|
|
|
nf kappab import into nucleus
|
GO:0042348 |
22 |
0.268
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.266
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.265
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.262
|
Human Mouse |
|
nuclear transport
|
GO:0051169 |
179 |
0.260
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.257
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.254
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.252
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.246
|
|
|
receptor biosynthetic process
|
GO:0032800 |
18 |
0.243
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.238
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.231
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.231
|
Mouse |
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.225
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.223
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.223
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.223
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.223
|
Mouse |
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.220
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.220
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.219
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.217
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.217
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.217
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.215
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.214
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.212
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.212
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.205
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.204
|
Mouse |
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.203
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.203
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.202
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.202
|
|
|
regulation of b cell activation
|
GO:0050864 |
24 |
0.200
|
Mouse |
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
2 |
0.198
|
|
|
response to peptidoglycan
|
GO:0032494 |
3 |
0.198
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.195
|
Human |
|
jak stat cascade
|
GO:0007259 |
46 |
0.195
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.194
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.190
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.190
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.188
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.183
|
|
|
positive regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000566 |
1 |
0.183
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.183
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.181
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.181
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.179
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.177
|
|
|
viral process
|
GO:0016032 |
146 |
0.177
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.177
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.173
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.172
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.170
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.170
|
Human |
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.170
|
|
|
necroptotic process
|
GO:0070266 |
16 |
0.170
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.169
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.166
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.164
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.162
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.161
|
Mouse |
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.160
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.154
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.154
|
Mouse |
|
lymphocyte migration
|
GO:0072676 |
28 |
0.153
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
21 |
0.153
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.152
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.150
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.150
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.148
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.146
|
Mouse |
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.146
|
Human |
|
post embryonic development
|
GO:0009791 |
2 |
0.145
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.145
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.143
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
6 |
0.141
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.137
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.136
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.136
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.135
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.135
|
Mouse |
|
protein targeting
|
GO:0006605 |
187 |
0.133
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.132
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.132
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.132
|
|
|
positive regulation of vitamin d biosynthetic process
|
GO:0060557 |
3 |
0.131
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.131
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.128
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.127
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.126
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.124
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.124
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.124
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.123
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
11 |
0.123
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.121
|
Human Mouse |
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.121
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.120
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.119
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.119
|
Mouse |
|
secretion
|
GO:0046903 |
254 |
0.119
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.117
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.116
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.115
|
|
|
positive regulation of interleukin 8 biosynthetic process
|
GO:0045416 |
8 |
0.115
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.112
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
13 |
0.112
|
|
|
natural killer cell activation
|
GO:0030101 |
12 |
0.111
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.110
|
Human Mouse |
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.109
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.106
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.106
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
39 |
0.106
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.105
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.105
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.104
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.103
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.102
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.102
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.102
|
Mouse |
|
positive regulation of calcidiol 1 monooxygenase activity
|
GO:0060559 |
3 |
0.101
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.100
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.100
|
|
|
response to exogenous dsrna
|
GO:0043330 |
10 |
0.100
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.099
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.098
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.098
|
Mouse |
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.097
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.097
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.096
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.096
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.096
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.095
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.094
|
Mouse |
|
regulation of protein localization
|
GO:0032880 |
296 |
0.094
|
Human |
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.093
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.092
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.092
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.091
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.091
|
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.090
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.090
|
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.088
|
Human |
|
jnk cascade
|
GO:0007254 |
80 |
0.088
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.087
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.086
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.086
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.085
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.085
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.084
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.084
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.084
|
|
|
response to nicotine
|
GO:0035094 |
12 |
0.084
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.083
|
Human |
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.082
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.082
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.082
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.081
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.081
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.081
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.080
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.078
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.077
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.076
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.076
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.074
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.073
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.073
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.073
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.073
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.072
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.072
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.071
|
Mouse |
|
tube morphogenesis
|
GO:0035239 |
95 |
0.071
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.070
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.069
|
|
|
tube development
|
GO:0035295 |
125 |
0.069
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.068
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.068
|
|
|
amide transport
|
GO:0042886 |
76 |
0.067
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.067
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.067
|
Mouse |
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.066
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.066
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.065
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.064
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.063
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.063
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.063
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.062
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.061
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.061
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.060
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.060
|
|
|
regulation of cd40 signaling pathway
|
GO:2000348 |
3 |
0.059
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.059
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.059
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.059
|
|
|
protein complex localization
|
GO:0031503 |
31 |
0.059
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.059
|
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.059
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.058
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.058
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.058
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.058
|
Mouse |
|
interleukin 12 biosynthetic process
|
GO:0042090 |
1 |
0.057
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.057
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.057
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
5 |
0.056
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.056
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
17 |
0.056
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.056
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
1 |
0.056
|
|
|
negative regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000562 |
1 |
0.056
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.055
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.055
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.055
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.054
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
22 |
0.053
|
Mouse |
|
single organism cellular localization
|
GO:1902580 |
332 |
0.053
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.053
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.052
|
|
|
t cell proliferation
|
GO:0042098 |
45 |
0.052
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.052
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.052
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.052
|
|
|
negative regulation of lymphocyte chemotaxis
|
GO:1901624 |
2 |
0.052
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.051
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.051
|
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.051
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.051
|
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.050
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.050
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.050
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.049
|
|
|
response to uv
|
GO:0009411 |
73 |
0.049
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
9 |
0.049
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.049
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.049
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.049
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.048
|
|
|
response to glucocorticoid
|
GO:0051384 |
13 |
0.048
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.047
|
|
|
rna processing
|
GO:0006396 |
255 |
0.047
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.047
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.047
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.046
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.046
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.046
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.046
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.045
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.045
|
Mouse |
|
response to hormone
|
GO:0009725 |
175 |
0.045
|
|
|
mirna metabolic process
|
GO:0010586 |
10 |
0.045
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.045
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.044
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.044
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.044
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.044
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.044
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.043
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.043
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.043
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.042
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.042
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.042
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.042
|
|
|
behavior
|
GO:0007610 |
112 |
0.042
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.042
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.042
|
|
|
response to dsrna
|
GO:0043331 |
25 |
0.041
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.041
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.041
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.041
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.040
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
4 |
0.040
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.040
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.040
|
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.039
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.039
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.039
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.038
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.037
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.037
|
|
|
regulation of chemokine mediated signaling pathway
|
GO:0070099 |
6 |
0.037
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.037
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.037
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
12 |
0.037
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.037
|
Mouse |
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.037
|
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
14 |
0.037
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.036
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.036
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.036
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.036
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
8 |
0.036
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.035
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.035
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.035
|
|