Homo sapiens

222 known processes

TNFAIP3

tumor necrosis factor, alpha-induced protein 3

(Aliases: A20,OTUD7C,MGC138687,MGC104522,MGC138688,TNFA1P2)

TNFAIP3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of immune response GO:0050778 159 1.000
cellular response to biotic stimulus GO:0071216 71 1.000
immune response activating signal transduction GO:0002757 90 1.000
lipopolysaccharide mediated signaling pathway GO:0031663 26 0.999
regulation of defense response GO:0031347 154 0.999
i kappab kinase nf kappab signaling GO:0007249 166 0.998
regulation of reactive oxygen species metabolic process GO:2000377 41 0.998
positive regulation of defense response GO:0031349 87 0.997
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.997
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.995
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.995
response to external biotic stimulus GO:0043207 261 0.995
defense response GO:0006952 315 0.995
Mouse
positive regulation of immune system process GO:0002684 283 0.993
reactive oxygen species biosynthetic process GO:1903409 4 0.993
activation of innate immune response GO:0002218 55 0.993
cytokine mediated signaling pathway GO:0019221 109 0.993
reactive nitrogen species metabolic process GO:2001057 3 0.992
cytokine production GO:0001816 247 0.990
immune effector process GO:0002252 159 0.990
response to molecule of bacterial origin GO:0002237 82 0.989
regulation of immune response GO:0050776 201 0.988
pattern recognition receptor signaling pathway GO:0002221 48 0.987
apoptotic signaling pathway GO:0097190 268 0.986
cellular response to lipid GO:0071396 127 0.985
leukocyte activation GO:0045321 164 0.984
Mouse
response to bacterium GO:0009617 144 0.979
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.977
negative regulation of apoptotic process GO:0043066 316 0.977
interleukin 6 production GO:0032635 37 0.977
Mouse
reactive oxygen species metabolic process GO:0072593 75 0.971
cell type specific apoptotic process GO:0097285 125 0.970
cell activation GO:0001775 213 0.970
Mouse
immune response regulating signaling pathway GO:0002764 97 0.968
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.968
cellular response to oxygen containing compound GO:1901701 276 0.965
response to biotic stimulus GO:0009607 276 0.962
lymphocyte activation GO:0046649 133 0.959
Mouse
immune system development GO:0002520 195 0.959
cellular response to molecule of bacterial origin GO:0071219 62 0.954
response to organonitrogen compound GO:0010243 156 0.952
Mouse
innate immune response activating signal transduction GO:0002758 48 0.949
response to interleukin 1 GO:0070555 47 0.943
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.924
regulation of response to external stimulus GO:0032101 222 0.921
activation of immune response GO:0002253 114 0.920
adaptive immune response GO:0002250 49 0.908
Mouse
immune response GO:0006955 307 0.898
Mouse
response to lipopolysaccharide GO:0032496 70 0.896
regulation of apoptotic signaling pathway GO:2001233 175 0.896
innate immune response GO:0045087 178 0.890
Mouse
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.889
response to cytokine GO:0034097 232 0.889
response to other organism GO:0051707 261 0.888
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.878
positive regulation of lymphocyte activation GO:0051251 73 0.878
negative regulation of cell death GO:0060548 345 0.878
toll like receptor signaling pathway GO:0002224 25 0.873
hemopoiesis GO:0030097 180 0.869
cellular ketone metabolic process GO:0042180 80 0.868
response to nitrogen compound GO:1901698 184 0.867
Mouse
regulation of lymphocyte activation GO:0051249 103 0.862
Mouse
response to oxygen containing compound GO:1901700 369 0.862
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.856
regulation of nitric oxide biosynthetic process GO:0045428 17 0.851
positive regulation of cell proliferation GO:0008284 301 0.847
Mouse
negative regulation of programmed cell death GO:0043069 321 0.840
nitric oxide biosynthetic process GO:0006809 20 0.830
positive regulation of cell death GO:0010942 263 0.827
cellular response to lipopolysaccharide GO:0071222 57 0.818
regulation of cell activation GO:0050865 125 0.812
Mouse
negative regulation of immune system process GO:0002683 136 0.799
regulation of cytokine biosynthetic process GO:0042035 35 0.761
cytokine biosynthetic process GO:0042089 37 0.759
regulation of cytokine production GO:0001817 232 0.758
regulation of response to wounding GO:1903034 101 0.749
Mouse
positive regulation of lymphocyte proliferation GO:0050671 46 0.741
positive regulation of leukocyte proliferation GO:0070665 48 0.734
regulation of transcription factor import into nucleus GO:0042990 39 0.724
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.712
chemokine metabolic process GO:0050755 4 0.709
regulation of immune effector process GO:0002697 91 0.708
regulation of leukocyte proliferation GO:0070663 67 0.705
erk1 and erk2 cascade GO:0070371 104 0.700
negative regulation of apoptotic signaling pathway GO:2001234 97 0.697
positive regulation of apoptotic process GO:0043065 246 0.697
positive regulation of innate immune response GO:0045089 79 0.692
endothelial cell apoptotic process GO:0072577 26 0.685
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.677
cellular response to endogenous stimulus GO:0071495 336 0.675
positive regulation of nf kappab import into nucleus GO:0042346 13 0.672
response to radiation GO:0009314 151 0.670
leukocyte differentiation GO:0002521 98 0.670
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.666
positive regulation of cytokine production GO:0001819 167 0.661
establishment of protein localization to organelle GO:0072594 172 0.658
Mouse
regulation of mapk cascade GO:0043408 262 0.654
mature natural killer cell chemotaxis GO:0035782 1 0.634
regulation of cellular amine metabolic process GO:0033238 11 0.626
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.607
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.598
lipid metabolic process GO:0006629 381 0.594
positive regulation of transcription factor import into nucleus GO:0042993 25 0.593
cellular amino acid metabolic process GO:0006520 116 0.593
mapk cascade GO:0000165 288 0.588
cellular response to cytokine stimulus GO:0071345 181 0.572
negative regulation of alpha beta t cell proliferation GO:0046642 1 0.555
regulation of leukocyte differentiation GO:1902105 61 0.554
negative regulation of multicellular organismal process GO:0051241 317 0.553
organic hydroxy compound biosynthetic process GO:1901617 71 0.548
steroid biosynthetic process GO:0006694 46 0.541
cellular response to nitrogen compound GO:1901699 144 0.540
positive regulation of developmental process GO:0051094 314 0.538
Mouse
intrinsic apoptotic signaling pathway GO:0097193 127 0.535
response to lipid GO:0033993 206 0.529
regulation of cell differentiation GO:0045595 393 0.527
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.518
regulation of granzyme b production GO:0071661 1 0.506
protein modification by small protein conjugation GO:0032446 342 0.503
regulation of chemokine biosynthetic process GO:0045073 4 0.498
muscle cell proliferation GO:0033002 35 0.488
positive regulation of cell differentiation GO:0045597 211 0.486
nitric oxide metabolic process GO:0046209 22 0.484
positive regulation of catabolic process GO:0009896 310 0.480
chemokine production GO:0032602 32 0.480
positive regulation of cell activation GO:0050867 81 0.470
positive regulation of chemokine biosynthetic process GO:0045080 3 0.461
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.460
interspecies interaction between organisms GO:0044419 156 0.459
cellular response to tumor necrosis factor GO:0071356 63 0.451
regulation of inflammatory response GO:0050727 46 0.451
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.450
regulation of cellular ketone metabolic process GO:0010565 50 0.446
leukocyte migration GO:0050900 107 0.445
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.442
Human
toll like receptor 2 signaling pathway GO:0034134 4 0.427
activation of protein kinase activity GO:0032147 90 0.424
regulation of cellular amino acid metabolic process GO:0006521 6 0.419
positive regulation of protein ubiquitination GO:0031398 53 0.418
negative regulation of cell proliferation GO:0008285 228 0.417
response to virus GO:0009615 126 0.415
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.415
chemokine biosynthetic process GO:0042033 4 0.411
myeloid leukocyte activation GO:0002274 34 0.409
response to growth factor GO:0070848 205 0.409
positive regulation of phosphorylation GO:0042327 394 0.405
regulation of cell cycle GO:0051726 393 0.401
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.396
fat soluble vitamin metabolic process GO:0006775 19 0.395
cellular response to oxidative stress GO:0034599 85 0.388
Mouse
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.385
vitamin d metabolic process GO:0042359 10 0.380
inflammatory response GO:0006954 79 0.371
Mouse
regulation of leukocyte activation GO:0002694 115 0.368
Mouse
regulation of heterotypic cell cell adhesion GO:0034114 14 0.367
vasculature development GO:0001944 181 0.365
regulation of cell cell adhesion GO:0022407 57 0.361
regulation of transferase activity GO:0051338 355 0.355
Mouse
positive regulation of myeloid cell differentiation GO:0045639 39 0.351
b cell activation GO:0042113 33 0.349
Mouse
regulation of interleukin 6 production GO:0032675 37 0.348
Mouse
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.348
steroid metabolic process GO:0008202 94 0.347
regulation of myeloid cell differentiation GO:0045637 81 0.346
cd40 signaling pathway GO:0023035 3 0.344
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.342
negative regulation of developmental process GO:0051093 247 0.340
regulation of intracellular protein transport GO:0033157 123 0.340
multi organism cellular process GO:0044764 156 0.332
regulation of innate immune response GO:0045088 97 0.321
negative regulation of response to external stimulus GO:0032102 83 0.318
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.315
regulation of chemokine production GO:0032642 31 0.309
cellular response to interleukin 1 GO:0071347 35 0.308
interleukin 2 production GO:0032623 20 0.306
response to organic cyclic compound GO:0014070 204 0.302
regulation of alcohol biosynthetic process GO:1902930 22 0.301
regulation of smooth muscle cell proliferation GO:0048660 28 0.297
regulation of steroid metabolic process GO:0019218 32 0.292
positive regulation of stress activated mapk cascade GO:0032874 60 0.291
regulation of protein localization to nucleus GO:1900180 85 0.290
Human
positive regulation of transport GO:0051050 336 0.288
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.287
smooth muscle cell proliferation GO:0048659 28 0.280
regulation of mononuclear cell proliferation GO:0032944 65 0.274
regulation of jnk cascade GO:0046328 73 0.274
regulation of cellular response to stress GO:0080135 244 0.273
positive regulation of apoptotic signaling pathway GO:2001235 70 0.268
positive regulation of programmed cell death GO:0043068 249 0.268
nf kappab import into nucleus GO:0042348 22 0.268
regulation of lipid biosynthetic process GO:0046890 47 0.266
receptor metabolic process GO:0043112 81 0.265
cellular macromolecule catabolic process GO:0044265 380 0.262
Human Mouse
nuclear transport GO:0051169 179 0.260
positive regulation of transferase activity GO:0051347 227 0.257
nitrogen compound transport GO:0071705 191 0.254
response to abiotic stimulus GO:0009628 336 0.252
cellular amine metabolic process GO:0044106 41 0.246
receptor biosynthetic process GO:0032800 18 0.243
positive regulation of protein phosphorylation GO:0001934 313 0.238
intracellular protein transport GO:0006886 270 0.231
response to oxidative stress GO:0006979 121 0.231
Mouse
positive regulation of t cell proliferation GO:0042102 33 0.225
negative regulation of cytokine production GO:0001818 82 0.223
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.223
cellular response to growth factor stimulus GO:0071363 197 0.223
regulation of kinase activity GO:0043549 314 0.223
Mouse
small molecule biosynthetic process GO:0044283 157 0.220
defense response to virus GO:0051607 71 0.220
lipid biosynthetic process GO:0008610 177 0.219
regulation of lymphocyte proliferation GO:0050670 64 0.217
cellular response to muramyl dipeptide GO:0071225 3 0.217
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.217
activation of nf kappab inducing kinase activity GO:0007250 9 0.215
regulation of response to biotic stimulus GO:0002831 55 0.214
positive regulation of chemokine production GO:0032722 22 0.212
lymphocyte proliferation GO:0046651 70 0.212
positive regulation of locomotion GO:0040017 186 0.205
intracellular receptor signaling pathway GO:0030522 104 0.204
Mouse
negative regulation of protein transport GO:0051224 75 0.203
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.203
positive regulation of acute inflammatory response GO:0002675 2 0.202
myeloid cell differentiation GO:0030099 117 0.202
regulation of b cell activation GO:0050864 24 0.200
Mouse
myd88 independent toll like receptor signaling pathway GO:0002756 2 0.198
response to peptidoglycan GO:0032494 3 0.198
modification dependent protein catabolic process GO:0019941 209 0.195
Human
jak stat cascade GO:0007259 46 0.195
epithelium development GO:0060429 227 0.194
positive regulation of protein kinase activity GO:0045860 190 0.190
extrinsic apoptotic signaling pathway GO:0097191 119 0.190
response to tumor necrosis factor GO:0034612 76 0.188
protein oligomerization GO:0051259 173 0.183
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.183
cellular response to organonitrogen compound GO:0071417 124 0.183
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.181
chemical homeostasis GO:0048878 306 0.181
blood vessel development GO:0001568 172 0.179
regulation of lipid metabolic process GO:0019216 96 0.177
viral process GO:0016032 146 0.177
regulation of protein localization to cell surface GO:2000008 15 0.177
cellular response to organic cyclic compound GO:0071407 127 0.173
positive regulation of mapk cascade GO:0043410 190 0.172
single organism cell adhesion GO:0098602 179 0.170
regulation of interleukin 8 production GO:0032677 49 0.170
Human
leukocyte proliferation GO:0070661 74 0.170
necroptotic process GO:0070266 16 0.170
alcohol biosynthetic process GO:0046165 52 0.169
peptide hormone secretion GO:0030072 50 0.166
morphogenesis of an epithelium GO:0002009 60 0.164
t cell differentiation in thymus GO:0033077 4 0.162
negative regulation of response to wounding GO:1903035 47 0.161
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.160
t cell receptor signaling pathway GO:0050852 21 0.154
negative regulation of defense response GO:0031348 47 0.154
Mouse
lymphocyte migration GO:0072676 28 0.153
positive regulation of interleukin 6 production GO:0032755 21 0.153
peptidyl serine autophosphorylation GO:0036289 2 0.152
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.150
programmed necrotic cell death GO:0097300 18 0.150
blood vessel morphogenesis GO:0048514 162 0.148
negative regulation of catalytic activity GO:0043086 335 0.146
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.146
Human
post embryonic development GO:0009791 2 0.145
negative regulation of intracellular signal transduction GO:1902532 183 0.145
protein catabolic process GO:0030163 325 0.143
necroptotic signaling pathway GO:0097527 6 0.141
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.137
cell projection organization GO:0030030 252 0.136
positive regulation of kinase activity GO:0033674 204 0.136
regulation of endothelial cell apoptotic process GO:2000351 24 0.135
response to reactive oxygen species GO:0000302 61 0.135
Mouse
protein targeting GO:0006605 187 0.133
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.132
calcium ion homeostasis GO:0055074 122 0.132
regulation of establishment of protein localization GO:0070201 242 0.132
positive regulation of vitamin d biosynthetic process GO:0060557 3 0.131
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.131
protein k63 linked ubiquitination GO:0070534 31 0.128
regulation of multi organism process GO:0043900 157 0.127
positive regulation of response to external stimulus GO:0032103 88 0.126
maintenance of location GO:0051235 112 0.124
regulation of map kinase activity GO:0043405 108 0.124
regulation of camp metabolic process GO:0030814 52 0.124
posttranscriptional regulation of gene expression GO:0010608 213 0.123
positive regulation of interleukin 2 production GO:0032743 11 0.123
protein localization to organelle GO:0033365 280 0.121
Human Mouse
protein autophosphorylation GO:0046777 123 0.121
amine metabolic process GO:0009308 44 0.120
positive regulation of lipid metabolic process GO:0045834 50 0.119
negative regulation of immune response GO:0050777 40 0.119
Mouse
secretion GO:0046903 254 0.119
signal transduction by phosphorylation GO:0023014 297 0.117
cellular homeostasis GO:0019725 196 0.116
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.115
positive regulation of interleukin 8 biosynthetic process GO:0045416 8 0.115
regulation of intracellular transport GO:0032386 195 0.112
positive regulation of nitric oxide biosynthetic process GO:0045429 13 0.112
natural killer cell activation GO:0030101 12 0.111
cellular protein catabolic process GO:0044257 261 0.110
Human Mouse
lymphocyte mediated immunity GO:0002449 48 0.109
cellular response to abiotic stimulus GO:0071214 117 0.106
regulation of homeostatic process GO:0032844 121 0.106
response to fibroblast growth factor GO:0071774 39 0.106
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.105
cytokine metabolic process GO:0042107 38 0.105
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.104
regulation of erk1 and erk2 cascade GO:0070372 99 0.103
peptidyl serine modification GO:0018209 106 0.102
regulation of cysteine type endopeptidase activity GO:2000116 127 0.102
tumor necrosis factor production GO:0032640 43 0.102
Mouse
positive regulation of calcidiol 1 monooxygenase activity GO:0060559 3 0.101
leukocyte cell cell adhesion GO:0007159 37 0.100
positive regulation of protein import into nucleus GO:0042307 46 0.100
response to exogenous dsrna GO:0043330 10 0.100
negative regulation of multi organism process GO:0043901 92 0.099
positive regulation of protein catabolic process GO:0045732 75 0.098
response to hydrogen peroxide GO:0042542 40 0.098
Mouse
regulation of peptidase activity GO:0052547 180 0.097
cellular metal ion homeostasis GO:0006875 146 0.097
regulation of interleukin 2 production GO:0032663 19 0.096
response to metal ion GO:0010038 84 0.096
regulation of protein ubiquitination GO:0031396 95 0.096
negative regulation of protein metabolic process GO:0051248 391 0.095
negative regulation of cell cycle GO:0045786 193 0.094
Mouse
regulation of protein localization GO:0032880 296 0.094
Human
regulation of myeloid leukocyte differentiation GO:0002761 39 0.093
single organismal cell cell adhesion GO:0016337 148 0.092
positive regulation of secretion GO:0051047 116 0.092
positive regulation of secretion by cell GO:1903532 108 0.091
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.091
regulation of cofactor metabolic process GO:0051193 3 0.090
regulation of protein catabolic process GO:0042176 155 0.090
interleukin 8 production GO:0032637 51 0.088
Human
jnk cascade GO:0007254 80 0.088
nucleocytoplasmic transport GO:0006913 176 0.087
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.086
regulation of endopeptidase activity GO:0052548 170 0.086
negative regulation of cell cycle process GO:0010948 121 0.085
organic hydroxy compound metabolic process GO:1901615 147 0.085
phosphatidylinositol mediated signaling GO:0048015 55 0.084
regulation of secretion GO:0051046 194 0.084
positive regulation of leukocyte differentiation GO:1902107 37 0.084
response to nicotine GO:0035094 12 0.084
ubiquitin dependent protein catabolic process GO:0006511 206 0.083
Human
cyclic nucleotide metabolic process GO:0009187 82 0.082
mononuclear cell proliferation GO:0032943 71 0.082
cell adhesion GO:0007155 325 0.082
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.081
antigen receptor mediated signaling pathway GO:0050851 38 0.081
positive regulation of ion transport GO:0043270 87 0.081
positive regulation of cytoplasmic transport GO:1903651 82 0.080
regulation of stress activated mapk cascade GO:0032872 84 0.078
t cell activation GO:0042110 99 0.077
regulation of protein import into nucleus GO:0042306 78 0.076
positive regulation of intracellular transport GO:0032388 104 0.076
peptidyl serine phosphorylation GO:0018105 101 0.074
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.073
receptor internalization GO:0031623 43 0.073
cellular response to radiation GO:0071478 65 0.073
cellular component disassembly GO:0022411 92 0.073
cytosolic calcium ion homeostasis GO:0051480 89 0.072
regulation of cell adhesion GO:0030155 166 0.072
regulation of protein kinase activity GO:0045859 289 0.071
Mouse
tube morphogenesis GO:0035239 95 0.071
ion homeostasis GO:0050801 230 0.070
regulation of ion homeostasis GO:2000021 73 0.069
tube development GO:0035295 125 0.069
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.068
positive regulation of intracellular protein transport GO:0090316 76 0.068
amide transport GO:0042886 76 0.067
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.067
regulation of protein serine threonine kinase activity GO:0071900 179 0.067
Mouse
cellular response to mechanical stimulus GO:0071260 39 0.066
alcohol metabolic process GO:0006066 114 0.066
positive regulation of protein localization to nucleus GO:1900182 48 0.065
alpha beta t cell differentiation GO:0046632 7 0.064
transcription factor import into nucleus GO:0042991 40 0.063
multicellular organismal homeostasis GO:0048871 67 0.063
signal transduction by p53 class mediator GO:0072331 72 0.063
protein polyubiquitination GO:0000209 110 0.062
mitotic cell cycle GO:0000278 326 0.061
cellular response to external stimulus GO:0071496 111 0.061
response to corticosteroid GO:0031960 15 0.060
regulation of ion transmembrane transport GO:0034765 132 0.060
regulation of cd40 signaling pathway GO:2000348 3 0.059
positive regulation of nucleotide metabolic process GO:0045981 230 0.059
regulation of peptide transport GO:0090087 62 0.059
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.059
protein complex localization GO:0031503 31 0.059
regulation of hormone levels GO:0010817 125 0.059
osteoclast differentiation GO:0030316 21 0.059
cellular response to dna damage stimulus GO:0006974 379 0.058
generation of neurons GO:0048699 152 0.058
negative regulation of binding GO:0051100 57 0.058
negative regulation of cell activation GO:0050866 33 0.058
Mouse
interleukin 12 biosynthetic process GO:0042090 1 0.057
defense response to other organism GO:0098542 129 0.057
coenzyme metabolic process GO:0006732 65 0.057
regulation of cd4 positive alpha beta t cell activation GO:2000514 5 0.056
second messenger mediated signaling GO:0019932 78 0.056
lymphocyte chemotaxis GO:0048247 17 0.056
digestive system development GO:0055123 75 0.056
negative regulation of cd4 positive alpha beta t cell activation GO:2000515 1 0.056
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.056
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
stress activated mapk cascade GO:0051403 93 0.055
negative regulation of immune effector process GO:0002698 38 0.055
positive regulation of proteolysis GO:0045862 142 0.054
negative regulation of inflammatory response GO:0050728 22 0.053
Mouse
single organism cellular localization GO:1902580 332 0.053
response to transition metal nanoparticle GO:1990267 29 0.053
production of molecular mediator of immune response GO:0002440 37 0.052
t cell proliferation GO:0042098 45 0.052
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.052
cytoplasmic transport GO:0016482 379 0.052
regulation of response to cytokine stimulus GO:0060759 46 0.052
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.052
female gamete generation GO:0007292 2 0.051
negative regulation of lipid metabolic process GO:0045833 38 0.051
cellular extravasation GO:0045123 21 0.051
response to endoplasmic reticulum stress GO:0034976 49 0.051
oxidoreduction coenzyme metabolic process GO:0006733 19 0.050
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.050
muscle structure development GO:0061061 98 0.050
positive regulation of behavior GO:0048520 60 0.049
response to uv GO:0009411 73 0.049
regulation of vitamin metabolic process GO:0030656 9 0.049
cellular chemical homeostasis GO:0055082 180 0.049
regulation of cytoplasmic transport GO:1903649 149 0.049
lymphocyte apoptotic process GO:0070227 20 0.049
cell activation involved in immune response GO:0002263 30 0.048
response to glucocorticoid GO:0051384 13 0.048
neurogenesis GO:0022008 169 0.047
rna processing GO:0006396 255 0.047
cell morphogenesis involved in differentiation GO:0000904 144 0.047
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.047
single organism nuclear import GO:1902593 104 0.046
positive regulation of cytokine biosynthetic process GO:0042108 25 0.046
divalent inorganic cation homeostasis GO:0072507 136 0.046
stress activated protein kinase signaling cascade GO:0031098 94 0.046
negative regulation of cellular component organization GO:0051129 235 0.045
response to inorganic substance GO:0010035 127 0.045
Mouse
response to hormone GO:0009725 175 0.045
mirna metabolic process GO:0010586 10 0.045
regulation of defense response to virus GO:0050688 33 0.045
modification of morphology or physiology of other organism GO:0035821 43 0.044
isoprenoid metabolic process GO:0006720 39 0.044
regulation of osteoclast differentiation GO:0045670 18 0.044
nucleotide catabolic process GO:0009166 408 0.044
negative regulation of protein maturation GO:1903318 142 0.044
protein complex disassembly GO:0043241 52 0.043
regulation of isoprenoid metabolic process GO:0019747 1 0.043
nucleoside triphosphate metabolic process GO:0009141 422 0.043
viral life cycle GO:0019058 132 0.042
ncrna processing GO:0034470 83 0.042
cellular response to uv GO:0034644 32 0.042
positive regulation of protein secretion GO:0050714 60 0.042
behavior GO:0007610 112 0.042
regulation of peptidyl serine phosphorylation GO:0033135 50 0.042
negative regulation of lipid biosynthetic process GO:0051055 22 0.042
response to dsrna GO:0043331 25 0.041
purine ribonucleoside metabolic process GO:0046128 437 0.041
regulation of protein secretion GO:0050708 86 0.041
regulation of cellular component movement GO:0051270 334 0.041
regulation of proteolysis GO:0030162 293 0.040
positive regulation of interferon beta biosynthetic process GO:0045359 4 0.040
protein acetylation GO:0006473 116 0.040
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.040
dolichol biosynthetic process GO:0019408 1 0.039
regulation of protein targeting GO:1903533 91 0.039
regulation of t cell activation GO:0050863 77 0.039
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.038
positive regulation of jak stat cascade GO:0046427 35 0.037
regulation of transmembrane transporter activity GO:0022898 74 0.037
regulation of chemokine mediated signaling pathway GO:0070099 6 0.037
positive regulation of cell migration GO:0030335 172 0.037
neuron projection development GO:0031175 106 0.037
positive regulation of b cell proliferation GO:0030890 12 0.037
lymphocyte homeostasis GO:0002260 4 0.037
Mouse
single organism carbohydrate metabolic process GO:0044723 193 0.037
positive regulation of sodium ion transport GO:0010765 14 0.037
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.036
leukocyte mediated immunity GO:0002443 59 0.036
regulation of protein transport GO:0051223 213 0.036
protein maturation GO:0051604 233 0.036
negative regulation of t cell proliferation GO:0042130 8 0.036
interaction with host GO:0051701 42 0.035
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
protein ubiquitination GO:0016567 314 0.035

TNFAIP3 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.634
disease of cellular proliferation DOID:14566 174 0.634
organ system cancer DOID:0050686 164 0.634
disease by infectious agent DOID:0050117 34 0.298
hematopoietic system disease DOID:74 100 0.085
immune system disease DOID:2914 155 0.085
central nervous system disease DOID:331 186 0.050
nervous system disease DOID:863 431 0.050