Homo sapiens

31 known processes

UPF2

UPF2 regulator of nonsense transcripts homolog (yeast)

(Aliases: DKFZp434D222,KIAA1408,smg-3,RENT2,MGC138835,MGC138834,HUPF2)

UPF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna catabolic process GO:0006402 56 0.999
male genitalia development GO:0030539 1 0.999
nuclear transcribed mrna catabolic process GO:0000956 48 0.999
rna catabolic process GO:0006401 71 0.999
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.997
cellular macromolecule catabolic process GO:0044265 380 0.918
intracellular mrna localization GO:0008298 1 0.900
histone mrna catabolic process GO:0071044 10 0.778
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.662
mrna metabolic process GO:0016071 175 0.650
nucleoside phosphate catabolic process GO:1901292 412 0.640
purine nucleotide catabolic process GO:0006195 405 0.631
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.480
ribonucleoside catabolic process GO:0042454 406 0.470
organophosphate catabolic process GO:0046434 430 0.455
male sex differentiation GO:0046661 25 0.393
positive regulation of translation GO:0045727 35 0.347
female gamete generation GO:0007292 2 0.305
rna phosphodiester bond hydrolysis GO:0090501 35 0.303
purine nucleoside catabolic process GO:0006152 398 0.300
neuromuscular synaptic transmission GO:0007274 5 0.275
enzyme linked receptor protein signaling pathway GO:0007167 303 0.248
ncrna processing GO:0034470 83 0.244
glycosyl compound catabolic process GO:1901658 413 0.241
microtubule cytoskeleton organization GO:0000226 176 0.230
regulation of cellular component biogenesis GO:0044087 281 0.223
ribonucleoprotein complex biogenesis GO:0022613 116 0.212
nucleoside catabolic process GO:0009164 408 0.206
purine ribonucleotide catabolic process GO:0009154 404 0.201
multicellular organismal aging GO:0010259 3 0.187
purine nucleoside monophosphate metabolic process GO:0009126 186 0.175
reproductive process GO:0022414 106 0.174
ncrna metabolic process GO:0034660 108 0.162
rna localization GO:0006403 41 0.160
vesicle mediated transport GO:0016192 371 0.158
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.148
translation GO:0006412 132 0.146
ribonucleoside triphosphate metabolic process GO:0009199 412 0.144
rrna metabolic process GO:0016072 40 0.139
purine nucleoside monophosphate catabolic process GO:0009128 158 0.137
snrna metabolic process GO:0016073 15 0.133
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.130
nucleoside triphosphate metabolic process GO:0009141 422 0.115
protein ubiquitination GO:0016567 314 0.110
oocyte differentiation GO:0009994 2 0.110
lipid metabolic process GO:0006629 381 0.106
positive regulation of cellular amine metabolic process GO:0033240 7 0.106
rna processing GO:0006396 255 0.105
single organism reproductive process GO:0044702 98 0.104
nucleoside triphosphate catabolic process GO:0009143 394 0.102
dna templated transcription initiation GO:0006352 35 0.095
purine containing compound catabolic process GO:0072523 411 0.095
positive regulation of protein complex assembly GO:0031334 86 0.091
intracellular protein transport GO:0006886 270 0.088
single organism cellular localization GO:1902580 332 0.087
glycerophospholipid metabolic process GO:0006650 84 0.087
glycerolipid metabolic process GO:0046486 107 0.084
purine nucleoside triphosphate catabolic process GO:0009146 392 0.083
nucleotide catabolic process GO:0009166 408 0.081
purine ribonucleoside metabolic process GO:0046128 437 0.080
regulation of translation GO:0006417 89 0.079
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.078
mapk cascade GO:0000165 288 0.075
purine ribonucleoside catabolic process GO:0046130 398 0.075
regulation of protein complex assembly GO:0043254 147 0.075
lipid modification GO:0030258 84 0.071
determination of adult lifespan GO:0008340 2 0.070
tissue regeneration GO:0042246 3 0.067
oogenesis GO:0048477 2 0.065
positive regulation of cellular component organization GO:0051130 376 0.065
microtubule based process GO:0007017 210 0.064
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.063
dna repair GO:0006281 198 0.063
reproductive system development GO:0061458 56 0.062
regulation of meiosis GO:0040020 3 0.061
positive regulation of phosphorylation GO:0042327 394 0.061
cellular ketone metabolic process GO:0042180 80 0.060
cellular response to dna damage stimulus GO:0006974 379 0.060
dosage compensation GO:0007549 3 0.059
ncrna catabolic process GO:0034661 14 0.059
ribonucleoprotein complex assembly GO:0022618 78 0.059
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.058
regulation of cellular amino acid metabolic process GO:0006521 6 0.058
protein localization to organelle GO:0033365 280 0.057
reproductive structure development GO:0048608 55 0.056
endomembrane system organization GO:0010256 196 0.054
negative regulation of posttranscriptional gene silencing GO:0060149 3 0.054
cytokinesis GO:0000910 96 0.054
post embryonic development GO:0009791 2 0.053
peptidyl serine modification GO:0018209 106 0.052
atp catabolic process GO:0006200 157 0.052
cellular lipid metabolic process GO:0044255 303 0.051
ribonucleoside triphosphate catabolic process GO:0009203 391 0.050
positive regulation of cellular component biogenesis GO:0044089 158 0.050
sex differentiation GO:0007548 45 0.049
cell cell signaling GO:0007267 155 0.048
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.048
nucleoside monophosphate metabolic process GO:0009123 191 0.047
phosphatidylinositol phosphorylation GO:0046854 24 0.046
phospholipid metabolic process GO:0006644 99 0.046
regulation of growth GO:0040008 165 0.045
cell morphogenesis GO:0000902 296 0.045
gonad development GO:0008406 34 0.044
regulation of cell differentiation GO:0045595 393 0.044
regulation of protein localization GO:0032880 296 0.044
embryonic epithelial tube formation GO:0001838 4 0.044
blastoderm segmentation GO:0007350 2 0.043
regulation of meiotic cell cycle GO:0051445 4 0.042
nucleocytoplasmic transport GO:0006913 176 0.042
protein localization to nucleus GO:0034504 136 0.040
segmentation GO:0035282 4 0.040
tripartite regional subdivision GO:0007351 2 0.040
regulation of cell division GO:0051302 116 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.039
positive regulation of catabolic process GO:0009896 310 0.039
modification dependent macromolecule catabolic process GO:0043632 212 0.039
cellular response to endogenous stimulus GO:0071495 336 0.039
positive regulation of cellular catabolic process GO:0031331 284 0.039
covalent chromatin modification GO:0016569 254 0.038
double strand break repair GO:0006302 101 0.038
neuromuscular junction development GO:0007528 3 0.038
defense response GO:0006952 315 0.037
regulation of cell maturation GO:1903429 3 0.037
posttranscriptional regulation of gene expression GO:0010608 213 0.037
embryonic morphogenesis GO:0048598 85 0.037
mitotic cell cycle GO:0000278 326 0.037
dephosphorylation GO:0016311 209 0.036
ribonucleotide catabolic process GO:0009261 405 0.036
chromatin organization GO:0006325 351 0.035
cellular response to oxygen containing compound GO:1901701 276 0.035
embryo development GO:0009790 123 0.034
cell projection organization GO:0030030 252 0.034
locomotory behavior GO:0007626 1 0.033
developmental process involved in reproduction GO:0003006 66 0.033
protein autophosphorylation GO:0046777 123 0.033
synaptic transmission GO:0007268 61 0.033
embryo development ending in birth or egg hatching GO:0009792 34 0.033
primary mirna processing GO:0031053 3 0.033
regulation of cell development GO:0060284 161 0.032
organelle fission GO:0048285 149 0.032
cell development GO:0048468 328 0.031
regulation of nuclear division GO:0051783 65 0.031
aging GO:0007568 66 0.031
long term memory GO:0007616 2 0.031
nucleoside monophosphate catabolic process GO:0009125 159 0.031
ribonucleoside monophosphate metabolic process GO:0009161 187 0.031
regulation of mrna processing GO:0050684 48 0.030
growth GO:0040007 202 0.030
cellular amine metabolic process GO:0044106 41 0.030
regulation of dna repair GO:0006282 47 0.030
cytoplasmic transport GO:0016482 379 0.030
regulation of dephosphorylation GO:0035303 96 0.029
protein modification by small protein conjugation GO:0032446 342 0.028
regulation of cell cycle GO:0051726 393 0.028
purine nucleoside triphosphate metabolic process GO:0009144 412 0.028
oocyte development GO:0048599 1 0.028
ribosome biogenesis GO:0042254 48 0.027
rna splicing GO:0008380 131 0.027
regulation of protein transport GO:0051223 213 0.026
regulation of small gtpase mediated signal transduction GO:0051056 156 0.025
cellular amino acid metabolic process GO:0006520 116 0.025
snrna transcription from rna polymerase ii promoter GO:0042795 7 0.025
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.025
protein maturation GO:0051604 233 0.024
nervous system development GO:0007399 293 0.024
histone methylation GO:0016571 60 0.023
cellular component morphogenesis GO:0032989 314 0.023
atp metabolic process GO:0046034 176 0.023
organelle assembly GO:0070925 176 0.023
nuclear division GO:0000280 128 0.023
anterior posterior axis specification embryo GO:0008595 2 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
immune response GO:0006955 307 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
negative regulation of gene silencing by rna GO:0060967 3 0.022
positive regulation of cell division GO:0051781 59 0.022
response to radiation GO:0009314 151 0.021
anatomical structure homeostasis GO:0060249 100 0.021
cell growth GO:0016049 160 0.021
negative regulation of programmed cell death GO:0043069 321 0.021
ras protein signal transduction GO:0007265 73 0.021
erk1 and erk2 cascade GO:0070371 104 0.021
cell cycle phase transition GO:0044770 173 0.021
cell part morphogenesis GO:0032990 137 0.020
regulation of dna metabolic process GO:0051052 153 0.020
response to biotic stimulus GO:0009607 276 0.020
chromatin modification GO:0016568 298 0.020
nuclear transport GO:0051169 179 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
regulation of establishment of protein localization GO:0070201 242 0.020
regulation of gene expression epigenetic GO:0040029 73 0.019
circulatory system development GO:0072359 262 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
regeneration GO:0031099 4 0.019
cell adhesion GO:0007155 325 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
actin filament based process GO:0030029 224 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
response to abiotic stimulus GO:0009628 336 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
dna recombination GO:0006310 77 0.018
regulation of intracellular transport GO:0032386 195 0.018
stem cell division GO:0017145 2 0.018
cellular macromolecular complex assembly GO:0034622 324 0.018
cellular protein complex disassembly GO:0043624 36 0.017
establishment of organelle localization GO:0051656 59 0.017
reproduction GO:0000003 63 0.017
macromolecule methylation GO:0043414 97 0.017
organ morphogenesis GO:0009887 147 0.017
anterior posterior axis specification GO:0009948 2 0.017
regulation of cellular amine metabolic process GO:0033238 11 0.017
amine metabolic process GO:0009308 44 0.017
regulation of binding GO:0051098 111 0.017
positive regulation of organelle organization GO:0010638 195 0.017
response to oxygen containing compound GO:1901700 369 0.017
cut metabolic process GO:0071043 3 0.017
histone modification GO:0016570 251 0.016
protein targeting GO:0006605 187 0.016
cell activation GO:0001775 213 0.016
response to fungus GO:0009620 4 0.016
positive regulation of histone modification GO:0031058 29 0.016
mitotic cell cycle process GO:1903047 286 0.016
signal transduction by phosphorylation GO:0023014 297 0.015
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.015
head development GO:0060322 108 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
phosphatidylinositol metabolic process GO:0046488 53 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
mitotic cell cycle phase transition GO:0044772 162 0.015
gtp metabolic process GO:0046039 239 0.015
maturation of ssu rrna GO:0030490 3 0.015
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.015
meiosis i GO:0007127 4 0.015
histone lysine methylation GO:0034968 50 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.014
neurological system process GO:0050877 163 0.014
double strand break repair via homologous recombination GO:0000724 50 0.014
regulation of cytoskeleton organization GO:0051493 177 0.014
behavior GO:0007610 112 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
tube morphogenesis GO:0035239 95 0.014
neuronal action potential GO:0019228 9 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
protein methylation GO:0006479 74 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
positive regulation of transport GO:0051050 336 0.014
regulation of cellular response to stress GO:0080135 244 0.014
regulation of nucleoside metabolic process GO:0009118 209 0.014
response to external biotic stimulus GO:0043207 261 0.013
regulation of cell growth GO:0001558 135 0.013
organelle localization GO:0051640 84 0.013
regulation of cell cycle process GO:0010564 266 0.013
negative regulation of phosphate metabolic process GO:0045936 267 0.013
response to wounding GO:0009611 168 0.013
protein import GO:0017038 130 0.013
defense response to other organism GO:0098542 129 0.013
centrosome organization GO:0051297 58 0.013
synapse organization GO:0050808 14 0.013
histone ubiquitination GO:0016574 31 0.013
regulation of protein catabolic process GO:0042176 155 0.013
chordate embryonic development GO:0043009 34 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.012
neurogenesis GO:0022008 169 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
rrna processing GO:0006364 35 0.012
gtp catabolic process GO:0006184 237 0.012
dna catabolic process GO:0006308 49 0.012
spermatid differentiation GO:0048515 4 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
establishment of rna localization GO:0051236 39 0.012
defense response to fungus GO:0050832 4 0.012
nuclear import GO:0051170 106 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
multi organism reproductive process GO:0044703 54 0.012
recombinational repair GO:0000725 50 0.011
negative regulation of immune system process GO:0002683 136 0.011
mating GO:0007618 1 0.011
regulation of proteolysis GO:0030162 293 0.011
response to nitrogen compound GO:1901698 184 0.011
exonucleolytic nuclear transcribed mrna catabolic process involved in deadenylation dependent decay GO:0043928 6 0.011
mitotic spindle elongation GO:0000022 4 0.011
protein catabolic process GO:0030163 325 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
epidermal growth factor receptor signaling pathway GO:0007173 39 0.011
transmission of nerve impulse GO:0019226 11 0.011
mrna processing GO:0006397 133 0.011
positive regulation of protein transport GO:0051222 135 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
regulation of protein maturation GO:1903317 150 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
negative regulation of multicellular organismal process GO:0051241 317 0.011
positive regulation of growth GO:0045927 58 0.011
adult locomotory behavior GO:0008344 1 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
cell projection morphogenesis GO:0048858 129 0.011
synaptic vesicle transport GO:0048489 5 0.011
rna polyadenylation GO:0043631 14 0.011
regulation of multi organism process GO:0043900 157 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
regulation of kinase activity GO:0043549 314 0.010
response to other organism GO:0051707 261 0.010
developmental growth GO:0048589 48 0.010
negative regulation of growth GO:0045926 97 0.010
regulation of nervous system development GO:0051960 88 0.010
protein complex disassembly GO:0043241 52 0.010
rna 3 end processing GO:0031123 35 0.010
deadenylation dependent decapping of nuclear transcribed mrna GO:0000290 1 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
actin filament organization GO:0007015 128 0.010
regulation of response to external stimulus GO:0032101 222 0.010
regulation of neurogenesis GO:0050767 82 0.010
skeletal system development GO:0001501 79 0.010
single organism nuclear import GO:1902593 104 0.010
endothelial cell migration GO:0043542 86 0.010
spindle elongation GO:0051231 4 0.010
microtubule organizing center organization GO:0031023 62 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
rna interference GO:0016246 4 0.010

UPF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.018
neurodegenerative disease DOID:1289 102 0.018
nervous system disease DOID:863 431 0.018
disease of cellular proliferation DOID:14566 174 0.012