IMP

Process View

Homo sapiens

3 genes annotated in human

negative regulation of gene silencing by rna

Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of gene silencing by rna"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of gene silencing by rna" (in gray)

Name	Description	Probability	Func Analog Organism
FOXD3	forkhead box D3	0.997
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.991
SP1	Sp1 transcription factor	0.957
SOX10	SRY (sex determining region Y)-box 10	0.905
HCFC1	host cell factor C1 (VP16-accessory protein)	0.891
SOX2	SRY (sex determining region Y)-box 2	0.874
PAX3	paired box 3	0.816
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.737
DAZL	deleted in azoospermia-like	0.683
TARDBP	TAR DNA binding protein	0.533
PUM2	pumilio homolog 2 (Drosophila)	0.518
IRF9	interferon regulatory factor 9	0.352
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.297
MOCS3	molybdenum cofactor synthesis 3	0.295
PARP12	poly (ADP-ribose) polymerase family, member 12	0.191
EXOSC10	exosome component 10	0.175
TOP1	topoisomerase (DNA) I	0.170
MEOX2	mesenchyme homeobox 2	0.122
HMGA1	high mobility group AT-hook 1	0.115
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.112
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.080
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.073
SMAD7	SMAD family member 7	0.061
SH3RF3	SH3 domain containing ring finger 3	0.056
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.044
CSNK2B	casein kinase 2, beta polypeptide	0.043
XPO7	exportin 7	0.042
SOX1	SRY (sex determining region Y)-box 1	0.041
POU3F3	POU class 3 homeobox 3	0.038	Human
PABPC1	poly(A) binding protein, cytoplasmic 1	0.037
HTT	huntingtin	0.037
SOX11	SRY (sex determining region Y)-box 11	0.035
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.034
POU3F2	POU class 3 homeobox 2	0.031	Human
ADARB1	adenosine deaminase, RNA-specific, B1	0.031
NKX2-1	NK2 homeobox 1	0.030
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.029
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.026
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.026
OTP	orthopedia homeobox	0.026
ZBTB17	zinc finger and BTB domain containing 17	0.024
NFYA	nuclear transcription factor Y, alpha	0.024
USP10	ubiquitin specific peptidase 10	0.024
SOX21	SRY (sex determining region Y)-box 21	0.024
HOXD12	homeobox D12	0.023
DZIP1	DAZ interacting protein 1	0.023
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.022
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.022
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.021
IFIT1	interferon-induced protein with tetratricopeptide repeats 1	0.021
DICER1	dicer 1, ribonuclease type III	0.021
KIAA0100	KIAA0100	0.020
LHX1	LIM homeobox 1	0.020
POU4F1	POU class 4 homeobox 1	0.020	Human
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.020
PURB	purine-rich element binding protein B	0.019
MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)	0.019
CSNK1G2	casein kinase 1, gamma 2	0.019
DTX3L	deltex 3-like (Drosophila)	0.018
VASP	vasodilator-stimulated phosphoprotein	0.018
NEUROG3	neurogenin 3	0.018
POU3F1	POU class 3 homeobox 1	0.018	Human
NONO	non-POU domain containing, octamer-binding	0.018
STK24	serine/threonine kinase 24	0.017
NOVA2	neuro-oncological ventral antigen 2	0.017
DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	0.017
FBXL15	F-box and leucine-rich repeat protein 15	0.017
MEX3B	mex-3 homolog B (C. elegans)	0.016
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.016
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.016
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.016
OLIG2	oligodendrocyte lineage transcription factor 2	0.016
CHN2	chimerin (chimaerin) 2	0.016
POU3F4	POU class 3 homeobox 4	0.016	Human
CHD8	chromodomain helicase DNA binding protein 8	0.015
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.015
TP73	tumor protein p73	0.015
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.014
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.014
PCBP2	poly(rC) binding protein 2	0.014
ESR1	estrogen receptor 1	0.014
SALL2	sal-like 2 (Drosophila)	0.014
TLX2	T-cell leukemia homeobox 2	0.014
SH3RF1	SH3 domain containing ring finger 1	0.014
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.014
COMT	catechol-O-methyltransferase	0.013
OCRL	oculocerebrorenal syndrome of Lowe	0.013
ZNF143	zinc finger protein 143	0.013
CHD4	chromodomain helicase DNA binding protein 4	0.013
THRAP3	thyroid hormone receptor associated protein 3	0.013
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.012
PDAP1	PDGFA associated protein 1	0.012
CUL1	cullin 1	0.012
MKRN1	makorin ring finger protein 1	0.012
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.012
TRIM39	tripartite motif containing 39	0.012
NKX2-8	NK2 homeobox 8	0.012
FAM120A	family with sequence similarity 120A	0.012
NPAS1	neuronal PAS domain protein 1	0.012
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.012
HOXB13	homeobox B13	0.011
VSX1	visual system homeobox 1	0.011
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.011
ATN1	atrophin 1	0.011
C20orf11	chromosome 20 open reading frame 11	0.011
NHLH2	nescient helix loop helix 2	0.011
C19orf6	chromosome 19 open reading frame 6	0.011
NKX2-2	NK2 homeobox 2	0.011
DCX	doublecortin	0.011
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.011
YTHDF1	YTH domain family, member 1	0.011
OSBP	oxysterol binding protein	0.011
RNF4	ring finger protein 4	0.011
PAX6	paired box 6	0.011
NKX6-1	NK6 homeobox 1	0.011
NCL	nucleolin	0.011
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.011
SALL3	sal-like 3 (Drosophila)	0.011
CASC3	cancer susceptibility candidate 3	0.011
FOXB1	forkhead box B1	0.010
NHLH1	nescient helix loop helix 1	0.010
PAX2	paired box 2	0.010
FMR1	fragile X mental retardation 1	0.010
HOXD3	homeobox D3	0.010
PAX5	paired box 5	0.010
NELL1	NEL-like 1 (chicken)	0.010
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.010
CD22	CD22 molecule	0.010
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.010
RNF114	ring finger protein 114	0.010