|
|
hippo signaling
|
GO:0035329 |
20 |
1.000
|
Human Mouse Fly |
|
|
negative regulation of hippo signaling
|
GO:0035331 |
6 |
1.000
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
1.000
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.999
|
Mouse |
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.998
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.996
|
Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.994
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.994
|
Fly |
|
|
vasculature development
|
GO:0001944 |
181 |
0.994
|
Mouse |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.994
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.992
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.990
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.985
|
Mouse |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.984
|
Mouse |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.982
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.981
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.979
|
Human Mouse |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.978
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.976
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.975
|
Human |
|
|
system process
|
GO:0003008 |
349 |
0.972
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.972
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.970
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.964
|
Human Mouse Fly |
|
|
action potential
|
GO:0001508 |
34 |
0.963
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.963
|
Human Mouse Fly |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.962
|
Mouse |
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.960
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.960
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.958
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.948
|
Human Mouse |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.944
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.940
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.938
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.935
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.935
|
Human Mouse |
|
|
blood circulation
|
GO:0008015 |
113 |
0.922
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.921
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.920
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.919
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.913
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.911
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.911
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.907
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.901
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.891
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.887
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.885
|
Human |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.883
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.882
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.874
|
Human |
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.873
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.872
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.871
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.864
|
Human |
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.864
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.862
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.855
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.855
|
Human |
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.847
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.844
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.839
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.833
|
Fly |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.833
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.831
|
Human Mouse Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.826
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.819
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.814
|
Human Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.811
|
Human Mouse Fly |
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.806
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.804
|
Mouse |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.804
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.802
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.799
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.795
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.793
|
Human Mouse Fly |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.793
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.792
|
Human |
|
|
negative regulation of vascular permeability
|
GO:0043116 |
7 |
0.791
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.789
|
|
|
|
regulation of action potential
|
GO:0098900 |
2 |
0.787
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.782
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.780
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.778
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.774
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.772
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.769
|
Zebrafish Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.766
|
Human Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.757
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.748
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.742
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.741
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.738
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.738
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.737
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.734
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.726
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.725
|
Mouse |
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.725
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.724
|
Human Mouse Fly |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.724
|
Human Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.723
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.719
|
Human Mouse |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.717
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.715
|
|
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.711
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.705
|
Fly |
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.705
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.700
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.697
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.697
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.695
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.694
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.690
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.688
|
|
|
|
negative regulation of membrane protein ectodomain proteolysis
|
GO:0051045 |
4 |
0.684
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.678
|
Human Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.674
|
Fly |
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.663
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.657
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.654
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.645
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.644
|
Mouse Fly |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.644
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.636
|
Mouse |
|
|
membrane depolarization during action potential
|
GO:0086010 |
10 |
0.623
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.623
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.617
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.604
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.603
|
Mouse |
|
|
regulation of hippo signaling
|
GO:0035330 |
8 |
0.593
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.593
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.592
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.590
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.581
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.575
|
Human |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.573
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.572
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.569
|
|
|
|
gliogenesis
|
GO:0042063 |
21 |
0.567
|
Fly |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.562
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.562
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.562
|
Human |
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.556
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
15 |
0.551
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.547
|
Mouse Fly |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.541
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.522
|
Human |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.521
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.520
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.515
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.514
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.508
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.491
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.489
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.488
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.488
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.483
|
Human |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.480
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.479
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.478
|
Human Mouse |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.477
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.476
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.474
|
Mouse |
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.473
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.471
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.468
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.468
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
17 |
0.467
|
Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.452
|
Human |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.450
|
Human |
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.450
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.448
|
|
|
|
regulation of vascular permeability
|
GO:0043114 |
11 |
0.448
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.445
|
|
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.443
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.443
|
Human |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.441
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.441
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.440
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.439
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.439
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.438
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.436
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.430
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.421
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.411
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.408
|
Mouse |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.403
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.402
|
Mouse |
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.402
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.398
|
Human |
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.397
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.377
|
|
|
|
axon cargo transport
|
GO:0008088 |
2 |
0.373
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.372
|
Mouse Fly |
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.368
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.365
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.363
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.363
|
Mouse Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.357
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.354
|
Fly |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.353
|
|
|
|
heart growth
|
GO:0060419 |
6 |
0.348
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.348
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.347
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.344
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.343
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.342
|
Human |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.341
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.340
|
Human |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.339
|
Human |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.338
|
Mouse |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.331
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.330
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.329
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.328
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.327
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.322
|
Human |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.317
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.313
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.311
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
5 |
0.309
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.306
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.304
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.298
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.298
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.293
|
Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.292
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.291
|
Mouse Fly |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.289
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.287
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.287
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.286
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.284
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.283
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.275
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.271
|
Fly |
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.270
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.269
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.269
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.268
|
Fly |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.268
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.264
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.262
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.261
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.259
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.259
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.258
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.256
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.250
|
Human Mouse Fly |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.249
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.249
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.249
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.248
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.247
|
Mouse |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.247
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.246
|
|
|
|
gastrulation with mouth forming second
|
GO:0001702 |
1 |
0.246
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.245
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.243
|
|
|
|
growth
|
GO:0040007 |
202 |
0.241
|
Mouse Fly |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.241
|
Human |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.241
|
Human |
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.238
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.236
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.235
|
Mouse Fly |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.233
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.231
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.231
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.231
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.230
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.230
|
Mouse |
|
|
dna packaging
|
GO:0006323 |
77 |
0.226
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.225
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.224
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.223
|
Fly |
|
|
schwann cell differentiation
|
GO:0014037 |
1 |
0.222
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.222
|
Mouse |
|
|
muscle system process
|
GO:0003012 |
81 |
0.219
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.218
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.216
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.216
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.213
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.211
|
Human |
|
|
stem cell proliferation
|
GO:0072089 |
25 |
0.211
|
Mouse Fly |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.211
|
|
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.210
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.209
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.207
|
Mouse |
|
|
axon ensheathment
|
GO:0008366 |
6 |
0.207
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.207
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.206
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.205
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.205
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.204
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.201
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.200
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.199
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.199
|
Human Mouse |
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.197
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.196
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.196
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
6 |
0.194
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.194
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.192
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.192
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.191
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.191
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.189
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.189
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.189
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.188
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.187
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.186
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.185
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.185
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.184
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.183
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.182
|
|
|
|
nephron tubule epithelial cell differentiation
|
GO:0072160 |
3 |
0.182
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.181
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.181
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.181
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.180
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.179
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.178
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.178
|
|
|
|
lymph vessel morphogenesis
|
GO:0036303 |
7 |
0.178
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.178
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.177
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.175
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.175
|
|
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.175
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.174
|
Mouse |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.173
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.171
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.171
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.171
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.171
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.169
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.167
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.166
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.166
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.165
|
Mouse Fly |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.165
|
|
|
|
negative regulation of stem cell proliferation
|
GO:2000647 |
3 |
0.164
|
|
|
|
regulation of myelination
|
GO:0031641 |
1 |
0.163
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.163
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.162
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.162
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.162
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.161
|
Human |
|
|
aging
|
GO:0007568 |
66 |
0.160
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.160
|
Zebrafish |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.160
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.159
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.159
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.158
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
5 |
0.157
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.155
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.154
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.154
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.152
|
Mouse Fly |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.152
|
|
|
|
glial cell differentiation
|
GO:0010001 |
11 |
0.151
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.150
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.149
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
2 |
0.148
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.148
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.148
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.148
|
Human |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.148
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.146
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.146
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.145
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.145
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.145
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.144
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.144
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.143
|
Mouse |
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.140
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.140
|
Mouse |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.140
|
Fly |
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.140
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.139
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.138
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.138
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.137
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.137
|
Zebrafish |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.137
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.136
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.135
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.135
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.134
|
Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.133
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.133
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.132
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.132
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.132
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.132
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.131
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.131
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.131
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.127
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.127
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.127
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.127
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.126
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.125
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.125
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.125
|
Mouse |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.124
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
15 |
0.123
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.123
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.123
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.122
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.120
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.119
|
Human |
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.117
|
Human |
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.115
|
Mouse |
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.114
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.114
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.113
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.113
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.112
|
|
|
|
response to starvation
|
GO:0042594 |
59 |
0.112
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.111
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.110
|
|
|
|
positive regulation of embryonic development
|
GO:0040019 |
6 |
0.110
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.108
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.108
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.108
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.108
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.107
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.105
|
Zebrafish |
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.105
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.104
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.103
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.103
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.102
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.102
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.102
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.101
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.101
|
Human Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.101
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.100
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.100
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.100
|
Human |
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.100
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.099
|
|
|
|
glial cell development
|
GO:0021782 |
7 |
0.098
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.097
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.097
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.096
|
Mouse |
|
|
pharynx development
|
GO:0060465 |
1 |
0.095
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.094
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.094
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.093
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.093
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.092
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.092
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.092
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.092
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.092
|
Human |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.092
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.091
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.091
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.091
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.090
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.089
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.089
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.089
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.088
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.088
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.087
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.086
|
Human |
|
|
cell growth
|
GO:0016049 |
160 |
0.086
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.085
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.085
|
Human |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.085
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.084
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.084
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.084
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.083
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.082
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.082
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.082
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.082
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.082
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.082
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.081
|
|
