Mus musculus

34 known processes

Traf3ip2

TRAF3 interacting protein 2

(Aliases: Act1,AI429613)

Traf3ip2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production involved in inflammatory response GO:0002534 9 0.998
positive regulation of defense response GO:0031349 124 0.921
regulation of cytokine production involved in inflammatory response GO:1900015 7 0.906
regulation of defense response GO:0031347 233 0.742
positive regulation of cytokine production involved in inflammatory response GO:1900017 7 0.706
activation of innate immune response GO:0002218 56 0.693
myeloid cell differentiation GO:0030099 233 0.618
immune response activating signal transduction GO:0002757 116 0.610
positive regulation of inflammatory response GO:0050729 47 0.555
inflammatory response GO:0006954 244 0.481
negative regulation of immune system process GO:0002683 209 0.471
immune response regulating signaling pathway GO:0002764 125 0.457
regulation of cytokine production GO:0001817 266 0.457
positive regulation of response to wounding GO:1903036 66 0.448
toll like receptor signaling pathway GO:0002224 38 0.389
regulation of cytokine biosynthetic process GO:0042035 59 0.385
lymphocyte proliferation GO:0046651 164 0.383
response to molecule of bacterial origin GO:0002237 143 0.363
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.353
positive regulation of protein homooligomerization GO:0032464 3 0.351
cellular response to lipopolysaccharide GO:0071222 77 0.345
positive regulation of cell death GO:0010942 224 0.328
regulation of inflammatory response GO:0050727 147 0.322
cytokine production GO:0001816 319 0.320
negative regulation of phosphorus metabolic process GO:0010563 184 0.299
activation of immune response GO:0002253 138 0.298
innate immune response activating signal transduction GO:0002758 50 0.279
i kappab kinase nf kappab signaling GO:0007249 85 0.279
negative regulation of cell activation GO:0050866 111 0.278
positive regulation of cytokine biosynthetic process GO:0042108 40 0.257
cytokine metabolic process GO:0042107 71 0.254
intrinsic apoptotic signaling pathway GO:0097193 132 0.234
apoptotic signaling pathway GO:0097190 306 0.224
regulation of protein oligomerization GO:0032459 4 0.217
regulation of response to wounding GO:1903034 189 0.215
eosinophil differentiation GO:0030222 1 0.211
interaction with host GO:0051701 22 0.210
leukocyte differentiation GO:0002521 342 0.206
positive regulation of interleukin 12 production GO:0032735 21 0.204
regulation of proteolysis GO:0030162 164 0.199
positive regulation of cytokine production GO:0001819 174 0.195
regulation of cysteine type endopeptidase activity GO:2000116 65 0.194
cellular response to cytokine stimulus GO:0071345 189 0.192
positive regulation of innate immune response GO:0045089 80 0.191
regulation of innate immune response GO:0045088 91 0.182
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.179
interleukin 10 secretion GO:0072608 4 0.171
homeostasis of number of cells GO:0048872 210 0.162
cellular response to molecule of bacterial origin GO:0071219 83 0.161
lymphocyte homeostasis GO:0002260 64 0.161
regulation of cellular ketone metabolic process GO:0010565 66 0.160
cation transport GO:0006812 399 0.160
regulation of cell activation GO:0050865 289 0.154
defense response to other organism GO:0098542 197 0.150
interferon beta production GO:0032608 16 0.143
interleukin 5 secretion GO:0072603 2 0.143
myeloid leukocyte differentiation GO:0002573 119 0.143
innate immune response GO:0045087 157 0.142
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.140
response to interleukin 1 GO:0070555 11 0.133
cellular response to biotic stimulus GO:0071216 92 0.132
regulation of multi organism process GO:0043900 111 0.127
regulation of cell cycle GO:0051726 281 0.126
modification by symbiont of host morphology or physiology GO:0044003 4 0.123
negative regulation of protein phosphorylation GO:0001933 126 0.122
negative regulation of phosphate metabolic process GO:0045936 184 0.120
cellular response to dna damage stimulus GO:0006974 207 0.118
production of molecular mediator of immune response GO:0002440 103 0.117
cytoplasmic transport GO:0016482 234 0.116
negative regulation of molecular function GO:0044092 258 0.114
positive regulation of programmed cell death GO:0043068 218 0.113
response to endoplasmic reticulum stress GO:0034976 53 0.113
regulation of jun kinase activity GO:0043506 40 0.112
regulation of apoptotic signaling pathway GO:2001233 197 0.111
circadian rhythm GO:0007623 114 0.110
regulation of b cell differentiation GO:0045577 23 0.110
cytokine biosynthetic process GO:0042089 68 0.110
activation of nf kappab inducing kinase activity GO:0007250 4 0.109
response to peptide GO:1901652 136 0.107
ion transmembrane transport GO:0034220 361 0.107
regulation of peptidase activity GO:0052547 96 0.106
nucleocytoplasmic transport GO:0006913 139 0.105
type i interferon production GO:0032606 29 0.103
pattern recognition receptor signaling pathway GO:0002221 47 0.102
regulation of ion transmembrane transporter activity GO:0032412 54 0.102
negative regulation of apoptotic signaling pathway GO:2001234 104 0.099
response to lipopolysaccharide GO:0032496 128 0.098
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.097
protein catabolic process GO:0030163 221 0.097
immunoglobulin production GO:0002377 73 0.096
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.094
extrinsic apoptotic signaling pathway GO:0097191 126 0.093
leukocyte homeostasis GO:0001776 79 0.092
response to inorganic substance GO:0010035 96 0.089
leukocyte proliferation GO:0070661 172 0.089
protein modification by small protein conjugation or removal GO:0070647 207 0.087
positive regulation of protein oligomerization GO:0032461 4 0.087
regulation of interferon beta production GO:0032648 13 0.087
cd24 biosynthetic process GO:0035724 1 0.086
regulation of interleukin 12 production GO:0032655 30 0.083
negative regulation of protein metabolic process GO:0051248 282 0.079
peptidyl amino acid modification GO:0018193 336 0.078
negative regulation of cellular protein metabolic process GO:0032269 247 0.076
mapk cascade GO:0000165 281 0.074
negative regulation of cytokine production GO:0001818 84 0.074
regulation of ion transport GO:0043269 215 0.073
ras protein signal transduction GO:0007265 77 0.073
cytokine mediated signaling pathway GO:0019221 115 0.073
regulation of secretion GO:0051046 274 0.073
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.072
negative regulation of regulatory t cell differentiation GO:0045590 2 0.072
production of molecular mediator involved in inflammatory response GO:0002532 21 0.072
positive regulation of hydrolase activity GO:0051345 148 0.070
regulation of lymphocyte activation GO:0051249 240 0.070
covalent chromatin modification GO:0016569 163 0.070
positive regulation of glial cell proliferation GO:0060252 4 0.070
negative regulation of t cell activation GO:0050868 65 0.070
glycoprotein metabolic process GO:0009100 116 0.069
cellular ion homeostasis GO:0006873 165 0.069
metal ion homeostasis GO:0055065 189 0.069
leukocyte mediated cytotoxicity GO:0001909 62 0.069
response to tumor necrosis factor GO:0034612 26 0.068
modulation by virus of host morphology or physiology GO:0019048 3 0.068
nik nf kappab signaling GO:0038061 14 0.068
response to organic cyclic compound GO:0014070 198 0.068
regulation of stress activated mapk cascade GO:0032872 69 0.067
cell adhesion GO:0007155 329 0.066
regulation of transmembrane transport GO:0034762 128 0.065
negative regulation of phosphorylation GO:0042326 166 0.065
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.065
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.063
dna recombination GO:0006310 92 0.062
regulation of cellular amino acid metabolic process GO:0006521 5 0.062
immunoglobulin secretion GO:0048305 17 0.061
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.061
cellular response to nitric oxide GO:0071732 4 0.061
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.060
negative regulation of cellular amine metabolic process GO:0033239 1 0.060
amine metabolic process GO:0009308 45 0.060
regulation of organelle organization GO:0033043 289 0.059
negative regulation of lymphocyte activation GO:0051250 91 0.059
apical constriction GO:0003383 4 0.058
regulation of protein homooligomerization GO:0032462 3 0.058
cellular response to lipid GO:0071396 145 0.056
regulation of killing of cells of other organism GO:0051709 4 0.056
regulation of kinase activity GO:0043549 249 0.054
regulation of ion transmembrane transport GO:0034765 119 0.054
glial cell apoptotic process GO:0034349 3 0.054
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.053
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.053
positive regulation of protein modification process GO:0031401 299 0.053
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.052
small gtpase mediated signal transduction GO:0007264 97 0.052
b cell homeostasis GO:0001782 34 0.051
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.051
interferon beta biosynthetic process GO:0045350 4 0.050
reactive oxygen species metabolic process GO:0072593 84 0.050
positive regulation of apoptotic process GO:0043065 217 0.049
negative regulation of protein modification process GO:0031400 163 0.048
regulation of interleukin 6 biosynthetic process GO:0045408 11 0.048
ossification GO:0001503 216 0.048
developmental maturation GO:0021700 193 0.048
mammary gland epithelial cell proliferation GO:0033598 24 0.047
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.047
regulation of mapk cascade GO:0043408 248 0.047
regulation of reactive oxygen species metabolic process GO:2000377 40 0.047
cellular response to inorganic substance GO:0071241 37 0.047
transmembrane transport GO:0055085 412 0.047
neuron apoptotic process GO:0051402 142 0.047
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.046
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.046
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.046
posttranscriptional regulation of gene expression GO:0010608 155 0.046
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.046
mammary gland lobule development GO:0061377 22 0.046
lipid biosynthetic process GO:0008610 179 0.046
regulation of interleukin 6 production GO:0032675 55 0.046
positive regulation of transmembrane transport GO:0034764 29 0.044
regulation of type i interferon production GO:0032479 22 0.044
regulation of transferase activity GO:0051338 263 0.044
chromatin organization GO:0006325 206 0.044
dna metabolic process GO:0006259 303 0.044
interleukin 12 production GO:0032615 32 0.044
t helper 2 cell cytokine production GO:0035745 4 0.044
regulation of interleukin 10 secretion GO:2001179 4 0.044
antibacterial peptide production GO:0002778 2 0.043
antigen receptor mediated signaling pathway GO:0050851 64 0.043
respiratory tube development GO:0030323 167 0.043
peptidyl serine phosphorylation GO:0018105 74 0.043
regulation of cytokine production involved in immune response GO:0002718 26 0.042
nuclear import GO:0051170 95 0.042
regulation of protein serine threonine kinase activity GO:0071900 157 0.041
nitrogen compound transport GO:0071705 271 0.041
positive regulation of apoptotic signaling pathway GO:2001235 95 0.041
immune effector process GO:0002252 321 0.041
regulation of cellular response to stress GO:0080135 159 0.041
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.041
tumor necrosis factor production GO:0032640 50 0.040
synaptic transmission GO:0007268 329 0.040
positive regulation of mapk cascade GO:0043410 170 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
defense response to bacterium GO:0042742 119 0.039
activation of meiosis GO:0090427 4 0.039
regulation of homeostatic process GO:0032844 182 0.039
natural killer cell activation GO:0030101 44 0.039
cellular metal ion homeostasis GO:0006875 151 0.039
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.039
organic hydroxy compound transport GO:0015850 93 0.038
carbohydrate derivative biosynthetic process GO:1901137 183 0.038
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.037
mammary gland epithelium development GO:0061180 65 0.037
neuron death GO:0070997 154 0.037
regulation of ion homeostasis GO:2000021 64 0.037
antigen processing and presentation of exogenous antigen GO:0019884 26 0.037
divalent metal ion transport GO:0070838 172 0.037
stress activated mapk cascade GO:0051403 80 0.037
liver development GO:0001889 66 0.037
adaptive immune response GO:0002250 155 0.037
negative regulation of hypersensitivity GO:0002884 3 0.037
positive regulation of killing of cells of other organism GO:0051712 3 0.036
immunoglobulin mediated immune response GO:0016064 69 0.036
regulation of interferon beta biosynthetic process GO:0045357 4 0.036
spermatogenesis GO:0007283 284 0.036
lipid transport GO:0006869 98 0.036
mitochondrion organization GO:0007005 134 0.036
regulation of cytokine secretion involved in immune response GO:0002739 4 0.036
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.036
regulation of cd24 biosynthetic process GO:2000559 1 0.036
regulation of interleukin 13 secretion GO:2000665 2 0.035
epithelial cell proliferation GO:0050673 174 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
organic cyclic compound catabolic process GO:1901361 295 0.034
interleukin 1 mediated signaling pathway GO:0070498 4 0.034
positive regulation of endopeptidase activity GO:0010950 43 0.034
natural killer cell proliferation GO:0001787 3 0.034
histone modification GO:0016570 159 0.034
positive regulation of adaptive immune response GO:0002821 61 0.034
cell type specific apoptotic process GO:0097285 268 0.034
lymphocyte activation involved in immune response GO:0002285 93 0.034
cell activation involved in immune response GO:0002263 126 0.034
somatic diversification of immunoglobulins GO:0016445 43 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
male gamete generation GO:0048232 285 0.032
regulation of leukocyte proliferation GO:0070663 121 0.032
cation transmembrane transport GO:0098655 266 0.032
amide transport GO:0042886 138 0.032
regulation of cytoskeleton organization GO:0051493 122 0.032
cytokine production involved in immune response GO:0002367 34 0.032
apoptotic mitochondrial changes GO:0008637 48 0.032
b cell differentiation GO:0030183 78 0.032
photoreceptor cell differentiation GO:0046530 52 0.031
jnk cascade GO:0007254 72 0.031
regulation of b cell mediated immunity GO:0002712 37 0.031
cell junction organization GO:0034330 77 0.031
extracellular structure organization GO:0043062 148 0.031
regulation of leukocyte differentiation GO:1902105 159 0.030
negative regulation of mapk cascade GO:0043409 65 0.030
regulation of jnk cascade GO:0046328 62 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.030
osteoclast differentiation GO:0030316 62 0.030
negative regulation of homeostatic process GO:0032845 71 0.029
negative regulation of b cell mediated immunity GO:0002713 7 0.029
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.029
mammary gland alveolus development GO:0060749 22 0.029
dna repair GO:0006281 107 0.029
defense response to gram positive bacterium GO:0050830 50 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
regulation of protein kinase activity GO:0045859 232 0.029
positive regulation of cellular component biogenesis GO:0044089 94 0.029
myotube differentiation GO:0014902 105 0.029
cellular protein complex assembly GO:0043623 116 0.028
regulation of protein localization GO:0032880 231 0.028
cellular response to organic cyclic compound GO:0071407 87 0.028
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 14 0.028
regulation of skeletal muscle fiber development GO:0048742 36 0.028
regulation of metal ion transport GO:0010959 106 0.028
regulation of interleukin 5 secretion GO:2000662 2 0.028
cellular response to interleukin 1 GO:0071347 8 0.028
monocyte extravasation GO:0035696 2 0.028
single organism nuclear import GO:1902593 95 0.028
protein import into nucleus GO:0006606 95 0.027
programmed necrotic cell death GO:0097300 28 0.027
antimicrobial peptide biosynthetic process GO:0002777 2 0.027
g1 s transition of mitotic cell cycle GO:0000082 57 0.027
leukocyte mediated immunity GO:0002443 174 0.027
cellular homeostasis GO:0019725 240 0.027
positive regulation of antimicrobial peptide production GO:0002225 1 0.027
anion transport GO:0006820 177 0.027
response to nitric oxide GO:0071731 4 0.026
negative regulation of humoral immune response mediated by circulating immunoglobulin GO:0002924 3 0.026
lateral inhibition GO:0046331 1 0.026
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.026
peptidyl lysine modification GO:0018205 77 0.026
odontogenesis GO:0042476 78 0.026
positive regulation of proteolysis GO:0045862 85 0.026
positive regulation of nervous system development GO:0051962 221 0.026
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.026
tube formation GO:0035148 140 0.025
modulation by symbiont of host cellular process GO:0044068 2 0.025
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 17 0.025
response to drug GO:0042493 75 0.025
positive regulation of cell cycle GO:0045787 92 0.025
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.025
regulation of mitotic cell cycle phase transition GO:1901990 73 0.025
calcium ion transmembrane transport GO:0070588 85 0.025
glycoprotein biosynthetic process GO:0009101 89 0.024
hepaticobiliary system development GO:0061008 67 0.024
protein oligomerization GO:0051259 67 0.024
regulation of transporter activity GO:0032409 57 0.024
regulation of membrane potential GO:0042391 192 0.024
t cell apoptotic process GO:0070231 39 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.024
regulation of gliogenesis GO:0014013 50 0.024
positive regulation of protein kinase activity GO:0045860 144 0.024
cellular amide metabolic process GO:0043603 58 0.024
regulation of ras protein signal transduction GO:0046578 114 0.024
glycerolipid biosynthetic process GO:0045017 50 0.024
regulation of response to biotic stimulus GO:0002831 38 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
positive regulation of cd24 biosynthetic process GO:2000560 1 0.023
positive regulation of binding GO:0051099 49 0.023
protein polyubiquitination GO:0000209 33 0.023
necroptotic signaling pathway GO:0097527 3 0.023
regulation of monocyte extravasation GO:2000437 2 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
response to water GO:0009415 1 0.023
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.022
circadian regulation of gene expression GO:0032922 48 0.022
positive regulation of protein complex assembly GO:0031334 45 0.022
myeloid dendritic cell differentiation GO:0043011 16 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
germ cell development GO:0007281 185 0.022
calcium ion transport GO:0006816 159 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.022
small molecule biosynthetic process GO:0044283 132 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
spleen development GO:0048536 39 0.022
regulation of cytoplasmic transport GO:1903649 112 0.022
toll like receptor 4 signaling pathway GO:0034142 9 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
response to amino acid GO:0043200 37 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.021
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.021
membrane organization GO:0061024 245 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
positive regulation of cell development GO:0010720 237 0.021
neutrophil chemotaxis GO:0030593 36 0.021
negative regulation of peptidase activity GO:0010466 46 0.021
regulation of binding GO:0051098 111 0.021
protein processing GO:0016485 163 0.021
rhythmic process GO:0048511 174 0.021
microtubule based process GO:0007017 236 0.021
positive regulation of leukocyte proliferation GO:0070665 73 0.021
positive regulation of kinase activity GO:0033674 155 0.021
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.021
plasma membrane organization GO:0007009 90 0.021
negative regulation of leukocyte differentiation GO:1902106 51 0.020
myeloid dendritic cell activation GO:0001773 25 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
intracellular protein transport GO:0006886 204 0.020
macromolecule catabolic process GO:0009057 281 0.020
muscle tissue development GO:0060537 308 0.020
dephosphorylation GO:0016311 129 0.020
humoral immune response GO:0006959 57 0.020
regulation of neuron differentiation GO:0045664 281 0.020
t cell mediated immunity GO:0002456 50 0.020
activation of meiosis involved in egg activation GO:0060466 2 0.020
membrane tubulation GO:0097320 4 0.020
regulation of hepatocyte proliferation GO:2000345 6 0.020
release of sequestered calcium ion into cytosol GO:0051209 42 0.020
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.020
positive regulation of peptidase activity GO:0010952 49 0.020
negative regulation of kinase activity GO:0033673 81 0.020
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.020
positive regulation of leukocyte mediated immunity GO:0002705 70 0.020
negative regulation of protein processing GO:0010955 79 0.020
calcium ion homeostasis GO:0055074 127 0.019
myeloid leukocyte activation GO:0002274 83 0.019
regulation of hydrolase activity GO:0051336 246 0.019
regulation of intracellular protein transport GO:0033157 82 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
regulation of protein binding GO:0043393 60 0.019
cellular response to tumor necrosis factor GO:0071356 21 0.019
inter male aggressive behavior GO:0002121 3 0.019
gtp catabolic process GO:0006184 143 0.019
organophosphate ester transport GO:0015748 28 0.019
skeletal muscle fiber development GO:0048741 58 0.019
calcium ion dependent exocytosis GO:0017156 35 0.019
carbohydrate homeostasis GO:0033500 128 0.019
protein import GO:0017038 101 0.018
positive regulation of isotype switching GO:0045830 15 0.018
positive regulation of stress activated mapk cascade GO:0032874 48 0.018
regulation of cell cycle phase transition GO:1901987 77 0.018
regulation of production of molecular mediator of immune response GO:0002700 65 0.018
regulation of immunoglobulin production GO:0002637 42 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
interspecies interaction between organisms GO:0044419 83 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
purine containing compound metabolic process GO:0072521 311 0.018
regulation of protein maturation GO:1903317 96 0.018
fat cell differentiation GO:0045444 160 0.018
regulation of interleukin 2 production GO:0032663 28 0.018
negative regulation of interleukin 13 secretion GO:2000666 1 0.018
response to organonitrogen compound GO:0010243 246 0.017
leukocyte apoptotic process GO:0071887 71 0.017
male gonad development GO:0008584 88 0.017
protein homooligomerization GO:0051260 43 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
positive regulation of jnk cascade GO:0046330 46 0.017
negative regulation of defense response GO:0031348 77 0.017
receptor mediated endocytosis GO:0006898 51 0.017
regulation of ossification GO:0030278 112 0.017
protein targeting GO:0006605 143 0.017
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
endomembrane system organization GO:0010256 147 0.017
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.017
regulation of lymphocyte proliferation GO:0050670 117 0.017
small molecule catabolic process GO:0044282 71 0.017
negative regulation of immune effector process GO:0002698 55 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
negative regulation of b cell activation GO:0050869 27 0.017
positive regulation of defense response to bacterium GO:1900426 1 0.017
positive regulation of jun kinase activity GO:0043507 30 0.017
regulation of receptor binding GO:1900120 4 0.017
positive regulation of interleukin 13 production GO:0032736 4 0.017
myeloid dendritic cell chemotaxis GO:0002408 2 0.016
apoptotic process involved in embryonic digit morphogenesis GO:1902263 3 0.016
regulation of erk1 and erk2 cascade GO:0070372 71 0.016
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.016
glycogen cell differentiation involved in embryonic placenta development GO:0060709 1 0.016
negative regulation of protein transport GO:0051224 46 0.016
pallium development GO:0021543 120 0.016
modulation by virus of host process GO:0019054 2 0.016
neutrophil apoptotic process GO:0001781 3 0.016
regulation of hormone levels GO:0010817 211 0.016
cell junction assembly GO:0034329 52 0.016
compound eye development GO:0048749 1 0.016
regulation of cell migration GO:0030334 219 0.016
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
regulation of natural killer cell proliferation GO:0032817 2 0.016
organophosphate catabolic process GO:0046434 232 0.016
activation induced cell death of t cells GO:0006924 10 0.016
monocarboxylic acid biosynthetic process GO:0072330 61 0.016
positive regulation of antibacterial peptide production GO:0002803 1 0.016
regulation of leukocyte mediated immunity GO:0002703 104 0.016
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.016
negative regulation of protein maturation GO:1903318 79 0.016
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.016
response to epidermal growth factor GO:0070849 4 0.016
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.016
negative regulation of sterol transport GO:0032372 4 0.015
regulation of b cell activation GO:0050864 81 0.015
regulation of cation channel activity GO:2001257 22 0.015
positive regulation of interferon beta production GO:0032728 8 0.015
t cell activation GO:0042110 289 0.015
response to metal ion GO:0010038 47 0.015
endothelial cell apoptotic process GO:0072577 9 0.015
actin filament organization GO:0007015 113 0.015
sterol metabolic process GO:0016125 58 0.015
regulation of hypersensitivity GO:0002883 10 0.015
vesicle organization GO:0016050 60 0.015
regulation of adaptive immune response GO:0002819 90 0.015
cellular amine metabolic process GO:0044106 44 0.015
regulation of nucleocytoplasmic transport GO:0046822 73 0.015
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.015
interleukin 6 production GO:0032635 58 0.015
cellular process regulating host cell cycle in response to virus GO:0060154 3 0.015
regulation of exocytosis GO:0017157 61 0.015

Traf3ip2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.431
disease of anatomical entity DOID:7 0 0.431
musculoskeletal system disease DOID:17 0 0.173
connective tissue disease DOID:65 0 0.173
hematopoietic system disease DOID:74 0 0.132
bone disease DOID:0080001 0 0.097
lupus erythematosus DOID:8857 0 0.082
hypersensitivity reaction disease DOID:0060056 0 0.082
hypersensitivity reaction type ii disease DOID:417 0 0.082
disease of metabolism DOID:0014667 0 0.056
acquired metabolic disease DOID:0060158 0 0.056
primary immunodeficiency disease DOID:612 0 0.052
blood protein disease DOID:620 0 0.052
agammaglobulinemia DOID:2583 0 0.052
common variable immunodeficiency DOID:12177 0 0.052
b cell deficiency DOID:2115 0 0.052
bone inflammation disease DOID:3342 0 0.050
arthritis DOID:848 0 0.050
carbohydrate metabolism disease DOID:0050013 0 0.026
glucose metabolism disease DOID:4194 0 0.026
diabetes mellitus DOID:9351 0 0.022