IMP

Process View

Mus musculus

8 genes annotated in mouse

cellular response to interleukin 1

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to interleukin 1"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to interleukin 1" (in gray)

Name	Description	Probability	Func Analog Organism
Traf6	TNF receptor-associated factor 6	0.764
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.719
Ccl2	chemokine (C-C motif) ligand 2	0.691
Myd88	myeloid differentiation primary response gene 88	0.584
Cd44	CD44 antigen	0.277
Icam1	intercellular adhesion molecule 1	0.230	Rat
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.191
Stat3	signal transducer and activator of transcription 3	0.179
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.175
Fas	Fas (TNF receptor superfamily member 6)	0.137	Rat
Il6	interleukin 6	0.133
Fgfr2	fibroblast growth factor receptor 2	0.125
Ptgs2	prostaglandin-endoperoxide synthase 2	0.122
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.093
Cd40	CD40 antigen	0.088
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.080
Cxcl2	chemokine (C-X-C motif) ligand 2	0.078	Rat
Ifng	interferon gamma	0.072
Tlr4	toll-like receptor 4	0.069
Tnf	tumor necrosis factor	0.062
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.058
Igh	immunoglobulin heavy chain complex	0.055
Ccl7	chemokine (C-C motif) ligand 7	0.052
Cxcl1	chemokine (C-X-C motif) ligand 1	0.048
Birc3	baculoviral IAP repeat-containing 3	0.045
Csf1	colony stimulating factor 1 (macrophage)	0.042
Bcl3	B-cell leukemia/lymphoma 3	0.039
Nos2	nitric oxide synthase 2, inducible	0.035	Rat
Il1rn	interleukin 1 receptor antagonist	0.035	Human
Irf1	interferon regulatory factor 1	0.030
Traf3ip2	TRAF3 interacting protein 2	0.028
Gbp5	guanylate binding protein 5	0.027
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.025
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.025
Osmr	oncostatin M receptor	0.023
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.023
Ccr2	chemokine (C-C motif) receptor 2	0.023
Mmp9	matrix metallopeptidase 9	0.022	Rat
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.020
Junb	Jun-B oncogene	0.020
Il1r1	interleukin 1 receptor, type I	0.019	Human Rat
Lyz2	lysozyme 2	0.019
Ch25h	cholesterol 25-hydroxylase	0.017
Socs3	suppressor of cytokine signaling 3	0.016
Ccl4	chemokine (C-C motif) ligand 4	0.016
Il10	interleukin 10	0.015
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.015
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.015
Dab1	disabled homolog 1 (Drosophila)	0.015
Irak3	interleukin-1 receptor-associated kinase 3	0.015
Aim2	absent in melanoma 2	0.014
Il1b	interleukin 1 beta	0.013
Tnip1	TNFAIP3 interacting protein 1	0.013
Ccl12	chemokine (C-C motif) ligand 12	0.013
Nlrp3	NLR family, pyrin domain containing 3	0.013
Ptgir	prostaglandin I receptor (IP)	0.012
Casp1	caspase 1	0.012
Lox	lysyl oxidase	0.012
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.012	Rat
Fbn1	fibrillin 1	0.011
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.011
Mapk1	mitogen-activated protein kinase 1	0.011
Mavs	mitochondrial antiviral signaling protein	0.011