Mus musculus

23 known processes

H2-DMb1

histocompatibility 2, class II, locus Mb1

(Aliases: H-2Mb1,AI385589,H2-Mb1)

H2-DMb1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
innate immune response GO:0045087 157 0.073
amine metabolic process GO:0009308 45 0.058
lymphocyte mediated immunity GO:0002449 139 0.044
cellular ketone metabolic process GO:0042180 84 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.043
cytokine production GO:0001816 319 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
immune effector process GO:0002252 321 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.037
cell adhesion GO:0007155 329 0.036
adaptive immune response GO:0002250 155 0.036
cellular amine metabolic process GO:0044106 44 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
antigen processing and presentation of peptide antigen GO:0048002 29 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.033
regulation of mapk cascade GO:0043408 248 0.033
oxidation reduction process GO:0055114 342 0.032
cellular chemical homeostasis GO:0055082 215 0.032
small gtpase mediated signal transduction GO:0007264 97 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
reactive nitrogen species metabolic process GO:2001057 0 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of transferase activity GO:0051338 263 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
cellular amino acid metabolic process GO:0006520 103 0.028
response to organic cyclic compound GO:0014070 198 0.027
cellular lipid metabolic process GO:0044255 323 0.027
positive regulation of protein modification process GO:0031401 299 0.027
lymphocyte proliferation GO:0046651 164 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
ras protein signal transduction GO:0007265 77 0.027
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.026
regulation of secretion by cell GO:1903530 249 0.026
positive regulation of cytokine production GO:0001819 174 0.026
antigen processing and presentation GO:0019882 47 0.025
regulation of secretion GO:0051046 274 0.025
positive regulation of cell development GO:0010720 237 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.025
macromolecule catabolic process GO:0009057 281 0.025
regulation of cell cycle GO:0051726 281 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
apoptotic signaling pathway GO:0097190 306 0.025
response to organonitrogen compound GO:0010243 246 0.025
t cell activation GO:0042110 289 0.025
peptidyl amino acid modification GO:0018193 336 0.024
cellular homeostasis GO:0019725 240 0.024
muscle tissue development GO:0060537 308 0.024
purine ribonucleotide metabolic process GO:0009150 290 0.024
aromatic compound catabolic process GO:0019439 286 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
negative regulation of cell proliferation GO:0008285 296 0.023
heterocycle catabolic process GO:0046700 280 0.023
glucose homeostasis GO:0042593 128 0.023
cell type specific apoptotic process GO:0097285 268 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
carbohydrate metabolic process GO:0005975 230 0.023
positive regulation of transferase activity GO:0051347 167 0.023
nucleotide metabolic process GO:0009117 332 0.022
negative regulation of immune system process GO:0002683 209 0.022
positive regulation of kinase activity GO:0033674 155 0.022
rho protein signal transduction GO:0007266 32 0.022
muscle cell differentiation GO:0042692 261 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
response to lipopolysaccharide GO:0032496 128 0.022
regulation of cell activation GO:0050865 289 0.022
cation homeostasis GO:0055080 212 0.022
male gamete generation GO:0048232 285 0.021
regulation of lipid metabolic process GO:0019216 118 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of kinase activity GO:0043549 249 0.021
ear development GO:0043583 200 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
leukocyte differentiation GO:0002521 342 0.021
lymphocyte differentiation GO:0030098 242 0.020
leukocyte proliferation GO:0070661 172 0.020
reactive oxygen species biosynthetic process GO:1903409 8 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
regulation of cytokine production GO:0001817 266 0.020
response to molecule of bacterial origin GO:0002237 143 0.020
defense response to other organism GO:0098542 197 0.020
mapk cascade GO:0000165 281 0.020
defense response to bacterium GO:0042742 119 0.020
spermatogenesis GO:0007283 284 0.020
sensory perception GO:0007600 245 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
cation transport GO:0006812 399 0.019
purine containing compound metabolic process GO:0072521 311 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
regulation of membrane potential GO:0042391 192 0.019
developmental maturation GO:0021700 193 0.019
regulation of protein kinase activity GO:0045859 232 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
regulation of neuron differentiation GO:0045664 281 0.018
fatty acid metabolic process GO:0006631 121 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
extracellular matrix organization GO:0030198 147 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
dephosphorylation GO:0016311 129 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of cell projection organization GO:0031344 206 0.018
b cell mediated immunity GO:0019724 71 0.018
leukocyte mediated immunity GO:0002443 174 0.018
negative regulation of cell activation GO:0050866 111 0.018
protein catabolic process GO:0030163 221 0.018
histone modification GO:0016570 159 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
synaptic transmission GO:0007268 329 0.017
locomotory behavior GO:0007626 195 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
sulfur compound metabolic process GO:0006790 100 0.017
positive regulation of nervous system development GO:0051962 221 0.017
protein maturation GO:0051604 176 0.017
carbohydrate homeostasis GO:0033500 128 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
regulation of defense response GO:0031347 233 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.016
cellular response to lipid GO:0071396 145 0.016
response to oxidative stress GO:0006979 123 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
germ cell development GO:0007281 185 0.016
epithelial cell development GO:0002064 159 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
response to extracellular stimulus GO:0009991 127 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
hormone secretion GO:0046879 128 0.016
calcium ion transport GO:0006816 159 0.016
striated muscle tissue development GO:0014706 293 0.016
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.016
regulation of ossification GO:0030278 112 0.016
regulation of organelle organization GO:0033043 289 0.016
cell killing GO:0001906 67 0.016
lateral inhibition GO:0046331 1 0.015
humoral immune response GO:0006959 57 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
negative regulation of t cell activation GO:0050868 65 0.015
covalent chromatin modification GO:0016569 163 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
chromatin modification GO:0016568 187 0.015
ossification GO:0001503 216 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
cognition GO:0050890 149 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
immunoglobulin mediated immune response GO:0016064 69 0.015
neuron death GO:0070997 154 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
hexose metabolic process GO:0019318 98 0.015
regulation of t cell activation GO:0050863 170 0.015
blood vessel morphogenesis GO:0048514 285 0.015
b cell activation GO:0042113 161 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
maintenance of location GO:0051235 89 0.015
lipid biosynthetic process GO:0008610 179 0.015
membrane organization GO:0061024 245 0.015
reactive oxygen species metabolic process GO:0072593 84 0.014
skeletal muscle organ development GO:0060538 163 0.014
dendrite development GO:0016358 115 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of cell motility GO:2000145 236 0.014
response to nutrient levels GO:0031667 109 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
regulation of blood pressure GO:0008217 93 0.014
mitochondrion organization GO:0007005 134 0.014
cell substrate adhesion GO:0031589 130 0.013
peptide secretion GO:0002790 114 0.013
spermatid differentiation GO:0048515 115 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
amide transport GO:0042886 138 0.013
regulation of hydrolase activity GO:0051336 246 0.013
sequestering of metal ion GO:0051238 19 0.013
defense response to gram positive bacterium GO:0050830 50 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
monosaccharide metabolic process GO:0005996 106 0.013
microtubule based process GO:0007017 236 0.013
neural tube development GO:0021915 160 0.013
methylation GO:0032259 134 0.013
activation of immune response GO:0002253 138 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
cytoplasmic transport GO:0016482 234 0.013
chromatin organization GO:0006325 206 0.013
positive regulation of cell migration GO:0030335 109 0.013
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 17 0.013
cell growth GO:0016049 130 0.013
inflammatory response GO:0006954 244 0.013
camera type eye development GO:0043010 266 0.012
regulation of adaptive immune response GO:0002819 90 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
dna metabolic process GO:0006259 303 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of adaptive immune response GO:0002821 61 0.012
response to peptide hormone GO:0043434 127 0.012
sequestering of calcium ion GO:0051208 18 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
dendritic spine development GO:0060996 30 0.012
stem cell differentiation GO:0048863 268 0.012
macromolecule methylation GO:0043414 120 0.012
protein ubiquitination GO:0016567 171 0.012
protein processing GO:0016485 163 0.012
epidermis development GO:0008544 187 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
actin filament organization GO:0007015 113 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
chemotaxis GO:0006935 247 0.012
intracellular protein transport GO:0006886 204 0.012
metal ion homeostasis GO:0055065 189 0.012
peptide transport GO:0015833 133 0.012
nuclear division GO:0000280 158 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
organelle fission GO:0048285 170 0.012
endocytosis GO:0006897 168 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
gtp metabolic process GO:0046039 144 0.012
negative regulation of cell cycle GO:0045786 123 0.012
nucleotide catabolic process GO:0009166 217 0.012
skeletal system development GO:0001501 356 0.012
fat cell differentiation GO:0045444 160 0.012
negative regulation of organelle organization GO:0010639 90 0.012
cell maturation GO:0048469 127 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
meiotic nuclear division GO:0007126 115 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
gtp catabolic process GO:0006184 143 0.011
regulation of innate immune response GO:0045088 91 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
negative regulation of defense response GO:0031348 77 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
urogenital system development GO:0001655 261 0.011
carbohydrate transport GO:0008643 62 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
purine containing compound catabolic process GO:0072523 213 0.011
negative regulation of t cell proliferation GO:0042130 38 0.011
lipid catabolic process GO:0016042 69 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of intracellular transport GO:0032386 159 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of neuron death GO:1901214 134 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
tissue homeostasis GO:0001894 115 0.011
cellular lipid catabolic process GO:0044242 52 0.011
nucleoside metabolic process GO:0009116 246 0.011
regulation of protein localization GO:0032880 231 0.011
regulation of b cell activation GO:0050864 81 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
activation of mapk activity GO:0000187 59 0.011
blood circulation GO:0008015 195 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
rhythmic process GO:0048511 174 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
response to peptide GO:1901652 136 0.011
learning or memory GO:0007611 148 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
response to oxygen levels GO:0070482 62 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
regulation of ion transport GO:0043269 215 0.011
renal system development GO:0072001 225 0.011
response to radiation GO:0009314 165 0.011
natural killer cell mediated immunity GO:0002228 29 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.010
response to light stimulus GO:0009416 135 0.010
response to monosaccharide GO:0034284 67 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
regulation of cell migration GO:0030334 219 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
angiogenesis GO:0001525 201 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
glycerolipid metabolic process GO:0046486 122 0.010
negative regulation of molecular function GO:0044092 258 0.010
calcium ion homeostasis GO:0055074 127 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
response to interferon gamma GO:0034341 34 0.010
regulation of vasculature development GO:1901342 88 0.010
mitotic cell cycle GO:0000278 195 0.010
regulation of system process GO:0044057 200 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
hexose transport GO:0008645 56 0.010
t cell proliferation GO:0042098 120 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010

H2-DMb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
central nervous system disease DOID:331 0 0.014
sensory system disease DOID:0050155 0 0.010