Mus musculus

0 known processes

Tspan4

tetraspanin 4

(Aliases: AI325509,Tspan-4,NAG-2,Tm4sf7,MGC102386,AI746565,D130042I01Rik)

Tspan4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.128
amine metabolic process GO:0009308 45 0.123
ion transmembrane transport GO:0034220 361 0.117
positive regulation of cellular amine metabolic process GO:0033240 5 0.116
transmembrane transport GO:0055085 412 0.107
regulation of cellular amino acid metabolic process GO:0006521 5 0.105
regulation of cellular amine metabolic process GO:0033238 20 0.102
cellular amine metabolic process GO:0044106 44 0.095
cellular ketone metabolic process GO:0042180 84 0.089
mapk cascade GO:0000165 281 0.087
oxidation reduction process GO:0055114 342 0.087
negative regulation of molecular function GO:0044092 258 0.079
immune effector process GO:0002252 321 0.078
regulation of cellular ketone metabolic process GO:0010565 66 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
regulation of mapk cascade GO:0043408 248 0.070
nucleotide metabolic process GO:0009117 332 0.069
regulation of apoptotic signaling pathway GO:2001233 197 0.067
hexose metabolic process GO:0019318 98 0.067
apoptotic signaling pathway GO:0097190 306 0.063
membrane organization GO:0061024 245 0.063
inflammatory response GO:0006954 244 0.058
circulatory system process GO:0003013 197 0.058
organic hydroxy compound metabolic process GO:1901615 203 0.057
positive regulation of protein phosphorylation GO:0001934 242 0.057
nitrogen compound transport GO:0071705 271 0.056
regulation of defense response GO:0031347 233 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
negative regulation of cellular protein metabolic process GO:0032269 247 0.054
striated muscle tissue development GO:0014706 293 0.052
monocarboxylic acid metabolic process GO:0032787 191 0.051
cellular lipid metabolic process GO:0044255 323 0.049
urogenital system development GO:0001655 261 0.048
regulation of response to wounding GO:1903034 189 0.048
purine nucleoside catabolic process GO:0006152 205 0.047
leukocyte differentiation GO:0002521 342 0.043
response to lipopolysaccharide GO:0032496 128 0.042
cell substrate adhesion GO:0031589 130 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
regulation of ossification GO:0030278 112 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.041
anion transport GO:0006820 177 0.041
cation transport GO:0006812 399 0.041
leukocyte mediated immunity GO:0002443 174 0.041
cellular response to molecule of bacterial origin GO:0071219 83 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
positive regulation of protein modification process GO:0031401 299 0.040
regulation of cell motility GO:2000145 236 0.039
lipid biosynthetic process GO:0008610 179 0.039
carbohydrate metabolic process GO:0005975 230 0.039
negative regulation of phosphorus metabolic process GO:0010563 184 0.039
negative regulation of phosphorylation GO:0042326 166 0.038
extracellular matrix organization GO:0030198 147 0.037
fat cell differentiation GO:0045444 160 0.037
cell adhesion GO:0007155 329 0.037
blood circulation GO:0008015 195 0.037
myeloid cell differentiation GO:0030099 233 0.037
regulation of protein kinase activity GO:0045859 232 0.036
regulation of blood pressure GO:0008217 93 0.036
lateral inhibition GO:0046331 1 0.036
monosaccharide metabolic process GO:0005996 106 0.036
response to nutrient levels GO:0031667 109 0.035
regulation of membrane potential GO:0042391 192 0.035
innate immune response GO:0045087 157 0.035
cellular modified amino acid metabolic process GO:0006575 63 0.035
purine containing compound metabolic process GO:0072521 311 0.034
activation of immune response GO:0002253 138 0.034
ossification GO:0001503 216 0.034
regulation of hydrolase activity GO:0051336 246 0.034
regulation of protein processing GO:0070613 96 0.034
aromatic compound catabolic process GO:0019439 286 0.034
regulation of peptidase activity GO:0052547 96 0.033
cation transmembrane transport GO:0098655 266 0.032
glycerolipid metabolic process GO:0046486 122 0.032
positive regulation of mapk cascade GO:0043410 170 0.031
purine ribonucleoside metabolic process GO:0046128 241 0.031
negative regulation of phosphate metabolic process GO:0045936 184 0.031
purine containing compound catabolic process GO:0072523 213 0.031
intracellular protein transport GO:0006886 204 0.030
male gamete generation GO:0048232 285 0.030
regulation of protein localization GO:0032880 231 0.030
regulation of cell migration GO:0030334 219 0.030
immune response activating signal transduction GO:0002757 116 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.029
cellular chemical homeostasis GO:0055082 215 0.029
heterocycle catabolic process GO:0046700 280 0.029
response to insulin GO:0032868 100 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
small molecule biosynthetic process GO:0044283 132 0.028
cellular carbohydrate metabolic process GO:0044262 119 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
dna metabolic process GO:0006259 303 0.028
angiogenesis GO:0001525 201 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
cellular homeostasis GO:0019725 240 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
regulation of intracellular transport GO:0032386 159 0.028
peptidyl amino acid modification GO:0018193 336 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.027
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.027
defense response to other organism GO:0098542 197 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
positive regulation of secretion GO:0051047 130 0.026
regulation of proteolysis GO:0030162 164 0.026
cellular response to cytokine stimulus GO:0071345 189 0.026
alcohol metabolic process GO:0006066 116 0.026
cellular nitrogen compound catabolic process GO:0044270 280 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
organic anion transport GO:0015711 137 0.026
nucleoside metabolic process GO:0009116 246 0.026
glycerophospholipid metabolic process GO:0006650 71 0.025
gland development GO:0048732 330 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
synaptic transmission GO:0007268 329 0.025
immune response regulating signaling pathway GO:0002764 125 0.024
carboxylic acid transport GO:0046942 100 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
response to oxidative stress GO:0006979 123 0.024
positive regulation of cell death GO:0010942 224 0.024
protein maturation GO:0051604 176 0.024
divalent metal ion transport GO:0070838 172 0.024
purine ribonucleoside catabolic process GO:0046130 205 0.024
regulation of organelle organization GO:0033043 289 0.024
response to extracellular stimulus GO:0009991 127 0.023
guanosine containing compound metabolic process GO:1901068 144 0.023
response to organonitrogen compound GO:0010243 246 0.023
negative regulation of protein modification process GO:0031400 163 0.023
extracellular structure organization GO:0043062 148 0.023
regulation of transferase activity GO:0051338 263 0.023
glycerolipid biosynthetic process GO:0045017 50 0.023
positive regulation of protein kinase activity GO:0045860 144 0.023
cytoplasmic transport GO:0016482 234 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of innate immune response GO:0045088 91 0.022
small molecule catabolic process GO:0044282 71 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of osteoblast differentiation GO:0045667 67 0.022
glucose metabolic process GO:0006006 92 0.022
regulation of endocytosis GO:0030100 69 0.022
lung development GO:0030324 164 0.022
cellular response to lipopolysaccharide GO:0071222 77 0.022
regulation of cell activation GO:0050865 289 0.022
endocytosis GO:0006897 168 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
regulation of secretion by cell GO:1903530 249 0.022
regulation of ion transport GO:0043269 215 0.022
regulation of anatomical structure size GO:0090066 178 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
mitochondrion organization GO:0007005 134 0.021
glucose homeostasis GO:0042593 128 0.021
positive regulation of defense response GO:0031349 124 0.021
organophosphate catabolic process GO:0046434 232 0.021
endomembrane system organization GO:0010256 147 0.021
carbohydrate homeostasis GO:0033500 128 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
cell matrix adhesion GO:0007160 68 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.020
regulation of hormone levels GO:0010817 211 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
protein localization to membrane GO:0072657 108 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
anion transmembrane transport GO:0098656 71 0.020
positive regulation of response to wounding GO:1903036 66 0.020
negative regulation of defense response GO:0031348 77 0.020
divalent inorganic cation transport GO:0072511 178 0.019
leukocyte proliferation GO:0070661 172 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
entry into host cell GO:0030260 15 0.019
negative regulation of multi organism process GO:0043901 68 0.019
sulfur compound metabolic process GO:0006790 100 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
epithelial cell proliferation GO:0050673 174 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
cell type specific apoptotic process GO:0097285 268 0.019
regulation of multi organism process GO:0043900 111 0.019
negative regulation of transferase activity GO:0051348 85 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
cation homeostasis GO:0055080 212 0.019
regulation of protein transport GO:0051223 163 0.019
macromolecule catabolic process GO:0009057 281 0.018
skeletal muscle organ development GO:0060538 163 0.018
organic acid biosynthetic process GO:0016053 86 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
muscle cell differentiation GO:0042692 261 0.018
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
wound healing GO:0042060 157 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
protein processing GO:0016485 163 0.018
phospholipid metabolic process GO:0006644 87 0.018
regulation of cell adhesion GO:0030155 154 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
action potential GO:0001508 78 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
cellular response to lipid GO:0071396 145 0.018
single organism nuclear import GO:1902593 95 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
organic acid transport GO:0015849 101 0.018
lymphocyte proliferation GO:0046651 164 0.017
nucleotide catabolic process GO:0009166 217 0.017
glycoprotein biosynthetic process GO:0009101 89 0.017
cell activation involved in immune response GO:0002263 126 0.017
glycoprotein metabolic process GO:0009100 116 0.017
respiratory system development GO:0060541 190 0.017
cytokine production GO:0001816 319 0.017
regulation of secretion GO:0051046 274 0.017
protein secretion GO:0009306 111 0.017
regulation of cytokine production GO:0001817 266 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
regulation of fat cell differentiation GO:0045598 81 0.017
respiratory tube development GO:0030323 167 0.017
chemotaxis GO:0006935 247 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
wnt signaling pathway GO:0016055 188 0.017
nucleoside catabolic process GO:0009164 206 0.017
epithelial cell development GO:0002064 159 0.017
sensory perception GO:0007600 245 0.016
cellular response to peptide hormone stimulus GO:0071375 92 0.016
renal system development GO:0072001 225 0.016
regulation of system process GO:0044057 200 0.016
calcium ion transport GO:0006816 159 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
regulation of transmembrane transport GO:0034762 128 0.016
negative regulation of ossification GO:0030279 49 0.016
protein localization to organelle GO:0033365 185 0.016
kidney development GO:0001822 213 0.016
cytokine mediated signaling pathway GO:0019221 115 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
response to monosaccharide GO:0034284 67 0.016
phagosome maturation GO:0090382 4 0.016
cellular response to peptide GO:1901653 92 0.016
response to inorganic substance GO:0010035 96 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.016
regulation of systemic arterial blood pressure GO:0003073 61 0.016
placenta development GO:0001890 140 0.016
bone development GO:0060348 120 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
myeloid leukocyte differentiation GO:0002573 119 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
sterol metabolic process GO:0016125 58 0.015
cellular response to carbohydrate stimulus GO:0071322 50 0.015
interspecies interaction between organisms GO:0044419 83 0.015
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.015
brown fat cell differentiation GO:0050873 36 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
renal system process GO:0003014 48 0.015
regulation of kinase activity GO:0043549 249 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
regulation of inflammatory response GO:0050727 147 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
positive regulation of map kinase activity GO:0043406 84 0.015
metal ion homeostasis GO:0055065 189 0.015
acetylcholine transport GO:0015870 2 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.014
protein catabolic process GO:0030163 221 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
response to acid chemical GO:0001101 111 0.014
t cell activation GO:0042110 289 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
nuclear import GO:0051170 95 0.014
regulation of glucose metabolic process GO:0010906 60 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
positive regulation of inflammatory response GO:0050729 47 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
response to growth factor GO:0070848 198 0.014
rhythmic process GO:0048511 174 0.014
l amino acid transport GO:0015807 32 0.014
multicellular organism growth GO:0035264 161 0.014
regulation of homeostatic process GO:0032844 182 0.014
somite development GO:0061053 81 0.014
positive regulation of kinase activity GO:0033674 155 0.014
spermatogenesis GO:0007283 284 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
negative regulation of proteolysis GO:0045861 74 0.014
sphingolipid metabolic process GO:0006665 45 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
stress activated mapk cascade GO:0051403 80 0.013
positive regulation of endocytosis GO:0045807 42 0.013
regulation of map kinase activity GO:0043405 120 0.013
muscle tissue development GO:0060537 308 0.013
cholesterol storage GO:0010878 4 0.013
response to peptide GO:1901652 136 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
organic hydroxy compound transport GO:0015850 93 0.013
positive regulation of transferase activity GO:0051347 167 0.013
skeletal system development GO:0001501 356 0.013
response to light stimulus GO:0009416 135 0.013
peptide transport GO:0015833 133 0.013
anatomical structure homeostasis GO:0060249 145 0.013
adaptive immune response GO:0002250 155 0.013
hindbrain development GO:0030902 128 0.013
t cell proliferation GO:0042098 120 0.013
cellular biogenic amine metabolic process GO:0006576 28 0.013
nuclear transport GO:0051169 139 0.013
nephron epithelium development GO:0072009 92 0.013
protein localization to vacuole GO:0072665 4 0.013
response to organic cyclic compound GO:0014070 198 0.013
positive regulation of ossification GO:0045778 47 0.013
plasma lipoprotein particle clearance GO:0034381 13 0.013
neuron apoptotic process GO:0051402 142 0.013
female meiosis chromosome segregation GO:0016321 1 0.012
amide transport GO:0042886 138 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
response to radiation GO:0009314 165 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
negative regulation of cell motility GO:2000146 61 0.012
protein targeting GO:0006605 143 0.012
leukocyte migration GO:0050900 124 0.012
regulation of protein targeting GO:1903533 61 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
detection of molecule of bacterial origin GO:0032490 2 0.012
regulation of monocyte chemotaxis GO:0090025 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
response to oxygen radical GO:0000305 16 0.012
organelle fission GO:0048285 170 0.012
steroid metabolic process GO:0008202 119 0.012
multi multicellular organism process GO:0044706 109 0.012
positive regulation of nervous system development GO:0051962 221 0.012
cholesterol catabolic process GO:0006707 5 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
positive regulation of cholesterol storage GO:0010886 3 0.012
regulation of angiogenesis GO:0045765 81 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
cofactor metabolic process GO:0051186 80 0.012
gtp metabolic process GO:0046039 144 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
neuronal action potential GO:0019228 54 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
axonogenesis GO:0007409 274 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
vascular process in circulatory system GO:0003018 62 0.012
negative regulation of immune system process GO:0002683 209 0.012
response to reactive oxygen species GO:0000302 56 0.012
neuron death GO:0070997 154 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
development of primary sexual characteristics GO:0045137 143 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.011
multicellular organismal signaling GO:0035637 91 0.011
monosaccharide transport GO:0015749 58 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
homeostasis of number of cells GO:0048872 210 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
negative regulation of growth GO:0045926 99 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
protein localization to plasma membrane GO:0072659 57 0.011
sterol homeostasis GO:0055092 45 0.011
negative regulation of cell activation GO:0050866 111 0.011
male gonad development GO:0008584 88 0.011
defense response to virus GO:0051607 68 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
regulation of neuron death GO:1901214 134 0.011
rho protein signal transduction GO:0007266 32 0.011
protein kinase b signaling GO:0043491 74 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
peptide hormone secretion GO:0030072 109 0.011
hormone metabolic process GO:0042445 86 0.011
regulation of tube size GO:0035150 57 0.011
circadian regulation of gene expression GO:0032922 48 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of immunological synapse formation GO:2000520 2 0.011
blood vessel morphogenesis GO:0048514 285 0.011
positive regulation of apoptotic cell clearance GO:2000427 3 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
regulation of protein maturation GO:1903317 96 0.011
gonad development GO:0008406 141 0.011
regulation of body fluid levels GO:0050878 162 0.011
hexose transport GO:0008645 56 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
heart contraction GO:0060047 93 0.011
negative regulation of neuron death GO:1901215 98 0.011
regulation of cellular response to stress GO:0080135 159 0.011
organic hydroxy compound catabolic process GO:1901616 25 0.011
hemostasis GO:0007599 78 0.011
response to peptide hormone GO:0043434 127 0.011
skeletal system morphogenesis GO:0048705 203 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
positive regulation of cell migration GO:0030335 109 0.010
hormone secretion GO:0046879 128 0.010
cellular response to inorganic substance GO:0071241 37 0.010
muscle system process GO:0003012 141 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
lipid homeostasis GO:0055088 63 0.010
cognition GO:0050890 149 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
positive regulation of cell development GO:0010720 237 0.010
cellular glucose homeostasis GO:0001678 52 0.010
hepaticobiliary system development GO:0061008 67 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
regulation of mitochondrion organization GO:0010821 27 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
positive regulation of coagulation GO:0050820 13 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
macromolecule glycosylation GO:0043413 55 0.010
recognition of apoptotic cell GO:0043654 3 0.010
locomotory behavior GO:0007626 195 0.010
t cell mediated immunity GO:0002456 50 0.010
regulation of removal of superoxide radicals GO:2000121 4 0.010
glutathione metabolic process GO:0006749 16 0.010

Tspan4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
inherited metabolic disorder DOID:655 0 0.041
bone disease DOID:0080001 0 0.035
disease of anatomical entity DOID:7 0 0.035
musculoskeletal system disease DOID:17 0 0.035
connective tissue disease DOID:65 0 0.035
bone development disease DOID:0080006 0 0.030
immune system disease DOID:2914 0 0.020
osteochondrodysplasia DOID:2256 0 0.016
nervous system disease DOID:863 0 0.016
hematopoietic system disease DOID:74 0 0.011