IMP

Process View

Mus musculus

3 genes annotated in mouse

positive regulation of cholesterol storage

Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cholesterol storage"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of cholesterol storage" (in gray)

Name	Description	Probability	Func Analog Organism
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.993
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.772
Apoa1	apolipoprotein A-I	0.649
Apoe	apolipoprotein E	0.363
Bcl2	B-cell leukemia/lymphoma 2	0.334
Ehd4	EH-domain containing 4	0.323	Mouse
Nphs2	nephrosis 2 homolog, podocin (human)	0.246
Vegfa	vascular endothelial growth factor A	0.246
C5ar1	complement component 5a receptor 1	0.208
Ccl2	chemokine (C-C motif) ligand 2	0.128
Ehd3	EH-domain containing 3	0.122	Mouse
Fabp4	fatty acid binding protein 4, adipocyte	0.121
Ldlr	low density lipoprotein receptor	0.117
C3ar1	complement component 3a receptor 1	0.114
F10	coagulation factor X	0.112
Myo1c	myosin IC	0.111
Gba	glucosidase, beta, acid	0.097
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.095
Dhcr24	24-dehydrocholesterol reductase	0.070
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.063
Lpl	lipoprotein lipase	0.062
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.061
Ppp3r1	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)	0.060
Gjb2	gap junction protein, beta 2	0.060
Dhcr7	7-dehydrocholesterol reductase	0.059
Saa3	serum amyloid A 3	0.059
Slc12a6	solute carrier family 12, member 6	0.055
Il1rn	interleukin 1 receptor antagonist	0.054
Apoc2	apolipoprotein C-II	0.053
Clec4a2	C-type lectin domain family 4, member a2	0.053
Fcgr1	Fc receptor, IgG, high affinity I	0.052
Cav1	caveolin 1, caveolae protein	0.048
Hgd	homogentisate 1, 2-dioxygenase	0.046
Fpr1	formyl peptide receptor 1	0.045
Myof	myoferlin	0.044
F7	coagulation factor VII	0.040
Msr1	macrophage scavenger receptor 1	0.038
Scd2	stearoyl-Coenzyme A desaturase 2	0.037
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.036
Tgm2	transglutaminase 2, C polypeptide	0.035
Bst1	bone marrow stromal cell antigen 1	0.035
Cd151	CD151 antigen	0.033
Ccl9	chemokine (C-C motif) ligand 9	0.033
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.032
Slc26a4	solute carrier family 26, member 4	0.031
Hpx	hemopexin	0.030
Fcgr4	Fc receptor, IgG, low affinity IV	0.030
Fcna	ficolin A	0.029
Aldob	aldolase B, fructose-bisphosphate	0.029
Fads2	fatty acid desaturase 2	0.029
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.028
Fgg	fibrinogen gamma chain	0.028
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.028
Fcgr3	Fc receptor, IgG, low affinity III	0.027
Cd5l	CD5 antigen-like	0.026
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.025
Clec4d	C-type lectin domain family 4, member d	0.025
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.024
Hp	haptoglobin	0.024
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.023
Pla2g12b	phospholipase A2, group XIIB	0.023
Mvd	mevalonate (diphospho) decarboxylase	0.023
Cfi	complement component factor i	0.023
Ncf1	neutrophil cytosolic factor 1	0.022
Clec4n	C-type lectin domain family 4, member n	0.021
Sqle	squalene epoxidase	0.020
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.020
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.020
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.019
Cybb	cytochrome b-245, beta polypeptide	0.018
Mapkapk2	MAP kinase-activated protein kinase 2	0.018
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.018
Tmem106a	transmembrane protein 106A	0.018
Chd4	chromodomain helicase DNA binding protein 4	0.017
Surf4	surfeit gene 4	0.017
Tcfec	transcription factor EC	0.017
Orm1	orosomucoid 1	0.017
Tbxas1	thromboxane A synthase 1, platelet	0.017
Cfb	complement factor B	0.017
Mcoln2	mucolipin 2	0.017
Ces1g	carboxylesterase 1G	0.016
Otc	ornithine transcarbamylase	0.016
Tmcc3	transmembrane and coiled coil domains 3	0.016
Fga	fibrinogen alpha chain	0.016
Arg1	arginase, liver	0.015
0610007P14Rik	RIKEN cDNA 0610007P14 gene	0.015
Apoa2	apolipoprotein A-II	0.015
Ghr	growth hormone receptor	0.015
Pdzk1	PDZ domain containing 1	0.015
Mmp12	matrix metallopeptidase 12	0.015
Mbl2	mannose-binding lectin (protein C) 2	0.015
Pilra	paired immunoglobin-like type 2 receptor alpha	0.015
Scd1	stearoyl-Coenzyme A desaturase 1	0.015
Tmem66	transmembrane protein 66	0.015
Cxcl13	chemokine (C-X-C motif) ligand 13	0.015
Lass2	LAG1 homolog, ceramide synthase 2	0.015
Ambp	alpha 1 microglobulin/bikunin	0.015
Plvap	plasmalemma vesicle associated protein	0.015
Dgcr2	DiGeorge syndrome critical region gene 2	0.015
F13b	coagulation factor XIII, beta subunit	0.014
Fez2	fasciculation and elongation protein zeta 2 (zygin II)	0.014
Il1a	interleukin 1 alpha	0.014
Man2a1	mannosidase 2, alpha 1	0.014
Hal	histidine ammonia lyase	0.014
Rragc	Ras-related GTP binding C	0.014
Fasn	fatty acid synthase	0.013
Rdh7	retinol dehydrogenase 7	0.013
Ccr1	chemokine (C-C motif) receptor 1	0.013
Actn4	actinin alpha 4	0.013
Ccl7	chemokine (C-C motif) ligand 7	0.013
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.013
Ap2a2	adaptor protein complex AP-2, alpha 2 subunit	0.013
Il1b	interleukin 1 beta	0.013
Hmox1	heme oxygenase (decycling) 1	0.013
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.013
Vnn3	vanin 3	0.013
Hk3	hexokinase 3	0.013
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.013
Aacs	acetoacetyl-CoA synthetase	0.013
Hnf4a	hepatic nuclear factor 4, alpha	0.013
Apom	apolipoprotein M	0.013
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.013
Cd36	CD36 antigen	0.012
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.012
Fabp1	fatty acid binding protein 1, liver	0.012
F2	coagulation factor II	0.012
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.012
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.012
Cfh	complement component factor h	0.012
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.012
Tspan4	tetraspanin 4	0.012
Hamp	hepcidin antimicrobial peptide	0.012
Ralb	v-ral simian leukemia viral oncogene homolog B (ras related)	0.012
Dag1	dystroglycan 1	0.012
Pecam1	platelet/endothelial cell adhesion molecule 1	0.012
Marco	macrophage receptor with collagenous structure	0.012	Mouse
Cd86	CD86 antigen	0.012
Lpin1	lipin 1	0.012
Angptl4	angiopoietin-like 4	0.011
Timp3	tissue inhibitor of metalloproteinase 3	0.011
Fads1	fatty acid desaturase 1	0.011
Gns	glucosamine (N-acetyl)-6-sulfatase	0.011
Aco1	aconitase 1	0.011
Prnp	prion protein	0.011
Sdc3	syndecan 3	0.011
Por	P450 (cytochrome) oxidoreductase	0.011
Lss	lanosterol synthase	0.011
Plg	plasminogen	0.011
9530008L14Rik	RIKEN cDNA 9530008L14 gene	0.011
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.011
Asgr2	asialoglycoprotein receptor 2	0.011
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.011
Igsf6	immunoglobulin superfamily, member 6	0.011
Ccl6	chemokine (C-C motif) ligand 6	0.011
Folr2	folate receptor 2 (fetal)	0.011
Hs6st1	heparan sulfate 6-O-sulfotransferase 1	0.011
Pparg	peroxisome proliferator activated receptor gamma	0.011
Plin2	perilipin 2	0.011
Agtr1a	angiotensin II receptor, type 1a	0.011
Kng1	kininogen 1	0.010
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.010
Stom	stomatin	0.010
Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M	0.010
Fgb	fibrinogen beta chain	0.010
Tpp1	tripeptidyl peptidase I	0.010
Ppp6r1	protein phosphatase 6, regulatory subunit 1	0.010
Vasp	vasodilator-stimulated phosphoprotein	0.010
Gatad2a	GATA zinc finger domain containing 2A	0.010
Dysf	dysferlin	0.010