Mus musculus

0 known processes

Sqle

squalene epoxidase

(Aliases: AI323792)

Sqle biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular alcohol biosynthetic process GO:0044108 3 1.000
Yeast
sterol metabolic process GO:0016125 58 1.000
Yeast
cholesterol metabolic process GO:0008203 56 0.996
alcohol biosynthetic process GO:0046165 43 0.991
Yeast
alcohol metabolic process GO:0006066 116 0.987
Yeast
lipid biosynthetic process GO:0008610 179 0.987
Yeast
cholesterol biosynthetic process GO:0006695 15 0.975
sterol biosynthetic process GO:0016126 17 0.971
Yeast
small molecule biosynthetic process GO:0044283 132 0.963
Yeast
isoprenoid biosynthetic process GO:0008299 9 0.872
steroid metabolic process GO:0008202 119 0.826
Yeast
cellular lipid metabolic process GO:0044255 323 0.748
fatty acid elongation GO:0030497 3 0.710
sterol transmembrane transport GO:0035382 2 0.642
cellular alcohol metabolic process GO:0044107 3 0.637
Yeast
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.587
organic hydroxy compound biosynthetic process GO:1901617 77 0.502
Yeast
organic hydroxy compound metabolic process GO:1901615 203 0.478
Yeast
cellular biogenic amine metabolic process GO:0006576 28 0.411
oxidation reduction process GO:0055114 342 0.319
Yeast
sphingolipid metabolic process GO:0006665 45 0.302
isoprenoid metabolic process GO:0006720 29 0.302
regulation of phospholipid catabolic process GO:0060696 2 0.291
steroid biosynthetic process GO:0006694 47 0.253
Yeast
demethylation GO:0070988 23 0.200
triglyceride biosynthetic process GO:0019432 17 0.180
liver development GO:0001889 66 0.160
phospholipid catabolic process GO:0009395 5 0.146
long chain fatty acid metabolic process GO:0001676 26 0.137
regulation of cellular amine metabolic process GO:0033238 20 0.134
membrane lipid metabolic process GO:0006643 53 0.131
neutral lipid biosynthetic process GO:0046460 18 0.128
positive regulation of triglyceride metabolic process GO:0090208 9 0.125
monocarboxylic acid metabolic process GO:0032787 191 0.102
cellular ketone metabolic process GO:0042180 84 0.094
organonitrogen compound biosynthetic process GO:1901566 192 0.089
cholesterol transport GO:0030301 38 0.085
response to light stimulus GO:0009416 135 0.083
response to radiation GO:0009314 165 0.080
response to nutrient levels GO:0031667 109 0.080
regulation of lipid metabolic process GO:0019216 118 0.078
sterol transport GO:0015918 38 0.078
cellular amine metabolic process GO:0044106 44 0.073
regulation of cellular ketone metabolic process GO:0010565 66 0.073
positive regulation of cellular amine metabolic process GO:0033240 5 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
very long chain fatty acid biosynthetic process GO:0042761 2 0.068
skin development GO:0043588 220 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
lipoprotein metabolic process GO:0042157 43 0.061
lipid transport GO:0006869 98 0.061
amine metabolic process GO:0009308 45 0.059
negative regulation of molecular function GO:0044092 258 0.059
rhodopsin mediated signaling pathway GO:0016056 4 0.059
monocarboxylic acid biosynthetic process GO:0072330 61 0.058
response to organic cyclic compound GO:0014070 198 0.057
coenzyme biosynthetic process GO:0009108 23 0.056
regulation of triglyceride metabolic process GO:0090207 17 0.056
nadph regeneration GO:0006740 2 0.050
thioester biosynthetic process GO:0035384 7 0.049
sterol import GO:0035376 2 0.048
positive regulation of protein modification process GO:0031401 299 0.047
organic anion transport GO:0015711 137 0.047
response to peptide GO:1901652 136 0.047
response to acid chemical GO:0001101 111 0.045
adaptation of rhodopsin mediated signaling GO:0016062 2 0.045
positive regulation of creb transcription factor activity GO:0032793 4 0.045
fatty acid elongation unsaturated fatty acid GO:0019368 2 0.044
gland development GO:0048732 330 0.044
regulation of phospholipid biosynthetic process GO:0071071 3 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
fatty acid metabolic process GO:0006631 121 0.039
positive regulation of cell projection organization GO:0031346 95 0.039
positive regulation of triglyceride biosynthetic process GO:0010867 6 0.038
regulation of hormone levels GO:0010817 211 0.038
ethanolamine containing compound metabolic process GO:0042439 18 0.037
response to extracellular stimulus GO:0009991 127 0.034
long chain fatty acid biosynthetic process GO:0042759 5 0.034
lipid localization GO:0010876 126 0.034
thioester metabolic process GO:0035383 19 0.033
sterol homeostasis GO:0055092 45 0.032
positive regulation of protein kinase activity GO:0045860 144 0.030
response to peptide hormone GO:0043434 127 0.030
cerebral cortex radially oriented cell migration GO:0021799 31 0.030
regulation of organelle organization GO:0033043 289 0.030
cellular response to lipid GO:0071396 145 0.029
small molecule catabolic process GO:0044282 71 0.029
regulation of triglyceride biosynthetic process GO:0010866 10 0.028
positive regulation of lipid metabolic process GO:0045834 40 0.028
molting cycle GO:0042303 90 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
organic acid transport GO:0015849 101 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of cell adhesion GO:0030155 154 0.027
ion transmembrane transport GO:0034220 361 0.026
transmembrane transport GO:0055085 412 0.026
anion transport GO:0006820 177 0.026
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.026
smoothened signaling pathway GO:0007224 105 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
response to monosaccharide GO:0034284 67 0.026
sphingolipid biosynthetic process GO:0030148 26 0.026
response to cholesterol GO:0070723 4 0.026
epidermis development GO:0008544 187 0.025
response to sterol GO:0036314 4 0.025
lung development GO:0030324 164 0.025
forebrain development GO:0030900 302 0.025
response to organonitrogen compound GO:0010243 246 0.025
glycerolipid biosynthetic process GO:0045017 50 0.024
negative regulation of multi organism process GO:0043901 68 0.024
methylation GO:0032259 134 0.024
ketone body metabolic process GO:1902224 3 0.024
mapk cascade GO:0000165 281 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
negative regulation of protein metabolic process GO:0051248 282 0.024
protein catabolic process GO:0030163 221 0.024
organic hydroxy compound transport GO:0015850 93 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
acyl coa biosynthetic process GO:0071616 7 0.022
cellular response to acid chemical GO:0071229 68 0.022
extracellular structure organization GO:0043062 148 0.022
chromatin organization GO:0006325 206 0.022
regulation of secretion GO:0051046 274 0.022
positive regulation of cell adhesion GO:0045785 80 0.022
regulation of plasma lipoprotein particle levels GO:0097006 23 0.022
detection of abiotic stimulus GO:0009582 60 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
response to steroid hormone GO:0048545 56 0.022
organophosphate catabolic process GO:0046434 232 0.022
ras protein signal transduction GO:0007265 77 0.022
cellular response to nutrient levels GO:0031669 64 0.022
positive regulation of organelle organization GO:0010638 128 0.021
cellular response to external stimulus GO:0071496 88 0.021
camera type eye development GO:0043010 266 0.021
cellular response to organic cyclic compound GO:0071407 87 0.021
regulation of transferase activity GO:0051338 263 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
regulation of cell cycle GO:0051726 281 0.021
response to yeast GO:0001878 6 0.021
response to phenylpropanoid GO:0080184 22 0.021
phospholipid biosynthetic process GO:0008654 36 0.021
positive regulation of cholesterol storage GO:0010886 3 0.020
respiratory tube development GO:0030323 167 0.020
response to low density lipoprotein particle GO:0055098 2 0.020
cation transmembrane transport GO:0098655 266 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
ribose phosphate biosynthetic process GO:0046390 59 0.020
histone modification GO:0016570 159 0.020
low density lipoprotein particle clearance GO:0034383 8 0.020
response to starvation GO:0042594 65 0.020
positive regulation of dna biosynthetic process GO:2000573 4 0.020
positive regulation of cell development GO:0010720 237 0.019
regulation of neuron differentiation GO:0045664 281 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
positive regulation of cholesterol biosynthetic process GO:0045542 3 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
response to oleic acid GO:0034201 1 0.019
hormone secretion GO:0046879 128 0.019
positive regulation of steroid biosynthetic process GO:0010893 4 0.018
respiratory system development GO:0060541 190 0.018
response to testosterone GO:0033574 3 0.018
inorganic ion transmembrane transport GO:0098660 234 0.018
cholesterol storage GO:0010878 4 0.018
cellular response to carbohydrate stimulus GO:0071322 50 0.018
positive regulation of secretion GO:0051047 130 0.018
asymmetric stem cell division GO:0098722 3 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
regulation of kinase activity GO:0043549 249 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.018
spermatogenesis GO:0007283 284 0.018
glycerolipid metabolic process GO:0046486 122 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.018
male gamete generation GO:0048232 285 0.017
sensory organ morphogenesis GO:0090596 242 0.017
regulation of homeostatic process GO:0032844 182 0.017
maintenance of location GO:0051235 89 0.017
acylglycerol biosynthetic process GO:0046463 18 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
nucleotide metabolic process GO:0009117 332 0.017
response to insulin GO:0032868 100 0.017
regulation of ras protein signal transduction GO:0046578 114 0.017
cellular response to steroid hormone stimulus GO:0071383 33 0.017
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
attachment of spindle microtubules to kinetochore GO:0008608 4 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
regulation of cell projection organization GO:0031344 206 0.017
cell adhesion GO:0007155 329 0.017
phospholipid metabolic process GO:0006644 87 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of neuron projection development GO:0010975 169 0.017
microtubule based process GO:0007017 236 0.016
activation of adenylate cyclase activity GO:0007190 4 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
negative regulation of cholesterol transport GO:0032375 4 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
cofactor metabolic process GO:0051186 80 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
sterol esterification GO:0034434 3 0.016
regulation of system process GO:0044057 200 0.016
blood circulation GO:0008015 195 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of mapk cascade GO:0043408 248 0.015
rho protein signal transduction GO:0007266 32 0.015
diterpenoid metabolic process GO:0016101 24 0.015
insulin secretion GO:0030073 89 0.015
response to inorganic substance GO:0010035 96 0.015
myeloid cell differentiation GO:0030099 233 0.015
leukocyte differentiation GO:0002521 342 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of map kinase activity GO:0043405 120 0.015
synaptic transmission GO:0007268 329 0.015
fatty acid biosynthetic process GO:0006633 41 0.015
acetyl coa biosynthetic process GO:0006085 5 0.015
rhythmic process GO:0048511 174 0.015
cellular aldehyde metabolic process GO:0006081 12 0.015
divalent metal ion transport GO:0070838 172 0.014
negative regulation of cholesterol efflux GO:0090370 4 0.014
regulation of protein kinase activity GO:0045859 232 0.014
pallium development GO:0021543 120 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
lipid homeostasis GO:0055088 63 0.014
positive regulation of transferase activity GO:0051347 167 0.014
membrane lipid biosynthetic process GO:0046467 32 0.014
t cell activation GO:0042110 289 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
regulation of secretion by cell GO:1903530 249 0.014
mrna metabolic process GO:0016071 84 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
limb development GO:0060173 166 0.014
regulation of chromatin modification GO:1903308 57 0.014
carbohydrate derivative catabolic process GO:1901136 231 0.013
sensory perception GO:0007600 245 0.013
spermatid development GO:0007286 108 0.013
glycerophospholipid catabolic process GO:0046475 5 0.013
response to oxidative stress GO:0006979 123 0.013
cytoplasmic transport GO:0016482 234 0.013
cellular chemical homeostasis GO:0055082 215 0.013
covalent chromatin modification GO:0016569 163 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
hair follicle development GO:0001942 85 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
erythrocyte differentiation GO:0030218 88 0.013
positive regulation of lipid biosynthetic process GO:0046889 18 0.013
regulation of transmembrane transport GO:0034762 128 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
hair cycle GO:0042633 90 0.013
neural precursor cell proliferation GO:0061351 121 0.013
regulation of cell activation GO:0050865 289 0.013
dna recombination GO:0006310 92 0.013
dna metabolic process GO:0006259 303 0.013
mating behavior sex discrimination GO:0048047 1 0.013
protein alkylation GO:0008213 81 0.013
circulatory system process GO:0003013 197 0.013
multicellular organismal signaling GO:0035637 91 0.013
inflammatory response GO:0006954 244 0.013
regulation of cholesterol homeostasis GO:2000188 9 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
positive regulation of nervous system development GO:0051962 221 0.013
ossification GO:0001503 216 0.013
cholesterol homeostasis GO:0042632 44 0.013
regulation of defense response GO:0031347 233 0.013
dendrite development GO:0016358 115 0.013
locomotory behavior GO:0007626 195 0.012
asymmetric neuroblast division GO:0055059 1 0.012
cation transport GO:0006812 399 0.012
negative regulation of sterol transport GO:0032372 4 0.012
sequestering of calcium ion GO:0051208 18 0.012
response to vitamin a GO:0033189 1 0.012
macromolecule catabolic process GO:0009057 281 0.012
peptide hormone secretion GO:0030072 109 0.012
regulation of histone modification GO:0031056 56 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
positive regulation of chromatin modification GO:1903310 28 0.012
macromolecule methylation GO:0043414 120 0.012
tissue homeostasis GO:0001894 115 0.012
heart contraction GO:0060047 93 0.012
lipoprotein catabolic process GO:0042159 7 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
cerebral cortex development GO:0021987 86 0.012
fat cell differentiation GO:0045444 160 0.012
cholesterol efflux GO:0033344 24 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
appendage development GO:0048736 166 0.012
stem cell differentiation GO:0048863 268 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
regulation of cellular response to stress GO:0080135 159 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
aromatic compound catabolic process GO:0019439 286 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
dna repair GO:0006281 107 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
response to stilbenoid GO:0035634 22 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
skeletal system development GO:0001501 356 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
negative regulation of defense response GO:0031348 77 0.011
heterocycle catabolic process GO:0046700 280 0.011
terpenoid metabolic process GO:0006721 25 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
actin cytoskeleton organization GO:0030036 220 0.011
protein methylation GO:0006479 81 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
positive regulation of kinase activity GO:0033674 155 0.011
homeostasis of number of cells GO:0048872 210 0.011
protein deacylation GO:0035601 36 0.011
single organism cell adhesion GO:0098602 156 0.011
chemotaxis GO:0006935 247 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.011
regulation of intracellular transport GO:0032386 159 0.011
cofactor biosynthetic process GO:0051188 41 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
regulation of cholesterol metabolic process GO:0090181 14 0.011
regulation of ion transport GO:0043269 215 0.011
compound eye development GO:0048749 1 0.011
purine containing compound metabolic process GO:0072521 311 0.011
kidney development GO:0001822 213 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
organelle disassembly GO:1903008 2 0.011
cytokine production GO:0001816 319 0.010
organelle assembly GO:0070925 177 0.010
regulation of phospholipase c activity GO:1900274 3 0.010
ribonucleotide biosynthetic process GO:0009260 59 0.010
carbohydrate metabolic process GO:0005975 230 0.010
regulation of dendritic spine development GO:0060998 22 0.010
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.010
substantia nigra development GO:0021762 2 0.010
rac protein signal transduction GO:0016601 13 0.010
mitotic cell cycle process GO:1903047 159 0.010
pyridine containing compound catabolic process GO:0072526 4 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
nucleoside phosphate catabolic process GO:1901292 222 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
regulation of chromatin organization GO:1902275 57 0.010
glucose homeostasis GO:0042593 128 0.010
inclusion body assembly GO:0070841 3 0.010
protein maturation GO:0051604 176 0.010
innate immune response GO:0045087 157 0.010
amide transport GO:0042886 138 0.010
fatty acid transmembrane transport GO:1902001 1 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
myeloid cell homeostasis GO:0002262 114 0.010

Sqle disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.073
inherited metabolic disorder DOID:655 0 0.073
lipid metabolism disorder DOID:3146 0 0.050
disease of cellular proliferation DOID:14566 0 0.023
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
neuropathy DOID:870 0 0.023
cancer DOID:162 0 0.019
central nervous system disease DOID:331 0 0.011
neuromuscular disease DOID:440 0 0.010