Mus musculus

35 known processes

Ptrf

polymerase I and transcript release factor

(Aliases: AW546441,Cavin,Cav-p60,MGC118550,2310075E07Rik)

Ptrf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.940
Mouse
notochord cell development GO:0060035 1 0.918
membrane raft assembly GO:0001765 3 0.907
positive regulation of metalloenzyme activity GO:0048554 3 0.887
actin filament organization GO:0007015 113 0.852
gas homeostasis GO:0033483 3 0.846
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 2 0.813
protein localization to plasma membrane GO:0072659 57 0.743
skeletal muscle organ development GO:0060538 163 0.727
protein localization to membrane GO:0072657 108 0.716
epithelial tube morphogenesis GO:0060562 303 0.704
heart trabecula formation GO:0060347 14 0.691
negative regulation of reactive oxygen species biosynthetic process GO:1903427 0 0.688
p38mapk cascade GO:0038066 4 0.674
wound healing GO:0042060 157 0.666
negative regulation of tyrosine phosphorylation of stat protein GO:0042532 3 0.635
blood vessel morphogenesis GO:0048514 285 0.634
muscle cell differentiation GO:0042692 261 0.628
muscle contraction GO:0006936 101 0.578
regulation of smooth muscle contraction GO:0006940 22 0.569
cell matrix adhesion GO:0007160 68 0.563
angiogenesis GO:0001525 201 0.559
establishment of protein localization to plasma membrane GO:0090002 34 0.556
circulatory system process GO:0003013 197 0.543
establishment of protein localization to membrane GO:0090150 54 0.543
regulation of p38mapk cascade GO:1900744 3 0.534
notochord cell differentiation GO:0060034 1 0.530
positive regulation of vasoconstriction GO:0045907 4 0.508
heart morphogenesis GO:0003007 178 0.507
amine metabolic process GO:0009308 45 0.493
positive regulation of peptidase activity GO:0010952 49 0.486
epithelial cell development GO:0002064 159 0.484
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.477
muscle system process GO:0003012 141 0.471
regulation of body fluid levels GO:0050878 162 0.467
negative regulation of anoikis GO:2000811 2 0.459
multi multicellular organism process GO:0044706 109 0.456
plasma membrane organization GO:0007009 90 0.444
response to ischemia GO:0002931 14 0.428
cardiac muscle tissue development GO:0048738 130 0.428
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.422
muscle fiber development GO:0048747 76 0.419
cytoplasmic microtubule organization GO:0031122 14 0.412
regulation of metalloenzyme activity GO:0048552 4 0.398
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.394
regulation of cell adhesion GO:0030155 154 0.394
endomembrane system organization GO:0010256 147 0.393
cell substrate adhesion GO:0031589 130 0.393
organelle localization GO:0051640 179 0.389
regulation of organ morphogenesis GO:2000027 144 0.384
plasma membrane repair GO:0001778 7 0.378
negative regulation of cellular amine metabolic process GO:0033239 1 0.376
anatomical structure homeostasis GO:0060249 145 0.374
regulation of proteolysis GO:0030162 164 0.367
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.365
nuclear division GO:0000280 158 0.357
regionalization GO:0003002 337 0.354
microtubule based process GO:0007017 236 0.354
regulation of intracellular transport GO:0032386 159 0.353
cardiac chamber morphogenesis GO:0003206 93 0.353
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.348
regulation of muscle contraction GO:0006937 49 0.348
positive regulation of homeostatic process GO:0032846 64 0.346
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.341
blood circulation GO:0008015 195 0.340
small gtpase mediated signal transduction GO:0007264 97 0.339
regulation of myotube differentiation GO:0010830 62 0.339
meiotic nuclear division GO:0007126 115 0.337
notochord development GO:0030903 20 0.336
cell fate commitment GO:0045165 210 0.332
regulation of protein kinase activity GO:0045859 232 0.316
reactive oxygen species metabolic process GO:0072593 84 0.315
ras protein signal transduction GO:0007265 77 0.305
mapk cascade GO:0000165 281 0.302
Mouse
myotube cell development GO:0014904 60 0.301
canonical wnt signaling pathway GO:0060070 130 0.296
regulation of peptidase activity GO:0052547 96 0.296
positive regulation of proteolysis GO:0045862 85 0.292
response to oxygen levels GO:0070482 62 0.285
membrane biogenesis GO:0044091 12 0.281
cellular lipid metabolic process GO:0044255 323 0.280
regulation of bmp signaling pathway GO:0030510 60 0.279
cardiac chamber development GO:0003205 108 0.277
heart trabecula morphogenesis GO:0061384 26 0.276
regulation of reactive oxygen species metabolic process GO:2000377 40 0.273
meiotic cell cycle GO:0051321 122 0.272
regulation of cellular response to stress GO:0080135 159 0.272
gland development GO:0048732 330 0.272
membrane organization GO:0061024 245 0.266
regulation of striated muscle cell differentiation GO:0051153 81 0.265
regulation of muscle system process GO:0090257 80 0.261
stress activated protein kinase signaling cascade GO:0031098 81 0.257
smooth muscle contraction GO:0006939 44 0.256
regulation of cellular ketone metabolic process GO:0010565 66 0.256
branching morphogenesis of an epithelial tube GO:0048754 159 0.253
regulation of actin cytoskeleton organization GO:0032956 84 0.252
cardiac muscle cell development GO:0055013 39 0.252
heart contraction GO:0060047 93 0.250
renal system development GO:0072001 225 0.247
negative regulation of cellular component organization GO:0051129 194 0.245
muscle tissue development GO:0060537 308 0.245
immune effector process GO:0002252 321 0.244
response to transforming growth factor beta GO:0071559 88 0.242
regulation of multi organism process GO:0043900 111 0.240
nucleus localization GO:0051647 20 0.236
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.235
reactive nitrogen species metabolic process GO:2001057 0 0.234
regulation of cellular amine metabolic process GO:0033238 20 0.233
regulation of removal of superoxide radicals GO:2000121 4 0.232
somitogenesis GO:0001756 69 0.230
response to growth factor GO:0070848 198 0.227
regulation of cell substrate adhesion GO:0010810 73 0.226
neutral lipid metabolic process GO:0006638 57 0.226
cell adhesion GO:0007155 329 0.224
negative regulation of molecular function GO:0044092 258 0.223
vasoconstriction GO:0042310 27 0.223
positive regulation of intracellular transport GO:0032388 70 0.221
regulation of cell migration GO:0030334 219 0.219
response to calcium ion GO:0051592 20 0.215
cardiocyte differentiation GO:0035051 87 0.214
cartilage development GO:0051216 140 0.214
developmental maturation GO:0021700 193 0.213
mammary gland duct morphogenesis GO:0060603 38 0.212
regulation of anatomical structure size GO:0090066 178 0.209
myeloid cell differentiation GO:0030099 233 0.209
regulation of pinocytosis GO:0048548 1 0.209
positive regulation of mapk cascade GO:0043410 170 0.209
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.208
negative regulation of nitric oxide synthase activity GO:0051001 3 0.206
digestive system development GO:0055123 200 0.203
urogenital system development GO:0001655 261 0.203
regulation of cellular amino acid metabolic process GO:0006521 5 0.201
microtubule cytoskeleton organization GO:0000226 157 0.201
wnt signaling pathway GO:0016055 188 0.199
regulation of anoikis GO:2000209 2 0.198
lateral inhibition GO:0046331 1 0.196
heart process GO:0003015 94 0.193
cellular response to growth factor stimulus GO:0071363 197 0.193
reactive oxygen species biosynthetic process GO:1903409 8 0.191
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.188
regulation of hydrolase activity GO:0051336 246 0.186
cellular amino acid metabolic process GO:0006520 103 0.185
acylglycerol metabolic process GO:0006639 55 0.182
cellular amine metabolic process GO:0044106 44 0.181
peptidyl tyrosine modification GO:0018212 145 0.181
striated muscle tissue development GO:0014706 293 0.181
negative regulation of wnt signaling pathway GO:0030178 73 0.180
cellular response to lipid GO:0071396 145 0.178
protein modification by small protein conjugation or removal GO:0070647 207 0.176
placenta development GO:0001890 140 0.174
morphogenesis of a branching epithelium GO:0061138 193 0.174
myotube differentiation GO:0014902 105 0.172
camera type eye development GO:0043010 266 0.171
cardiac cell development GO:0055006 41 0.171
striated muscle cell development GO:0055002 125 0.169
innate immune response GO:0045087 157 0.168
peptidyl tyrosine phosphorylation GO:0018108 143 0.168
regulation of cell motility GO:2000145 236 0.168
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.167
mammary gland morphogenesis GO:0060443 54 0.167
negative regulation of protein phosphorylation GO:0001933 126 0.166
negative regulation of epithelial cell proliferation GO:0050680 64 0.166
regulation of map kinase activity GO:0043405 120 0.165
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.164
stress activated mapk cascade GO:0051403 80 0.164
oxidation reduction process GO:0055114 342 0.164
Mouse
bmp signaling pathway GO:0030509 93 0.164
regulation of heart contraction GO:0008016 77 0.163
vascular process in circulatory system GO:0003018 62 0.162
plasma membrane raft organization GO:0044857 2 0.160
regulation of blood vessel size GO:0050880 56 0.159
negative regulation of phosphorus metabolic process GO:0010563 184 0.159
negative regulation of bmp signaling pathway GO:0030514 35 0.158
regulation of t cell activation GO:0050863 170 0.157
regulation of homeostatic process GO:0032844 182 0.156
actomyosin structure organization GO:0031032 56 0.156
nitric oxide biosynthetic process GO:0006809 25 0.151
regulation of canonical wnt signaling pathway GO:0060828 82 0.150
positive regulation of striated muscle cell differentiation GO:0051155 35 0.150
mitochondrion organization GO:0007005 134 0.149
fatty acid metabolic process GO:0006631 121 0.148
negative regulation of cell proliferation GO:0008285 296 0.148
membrane assembly GO:0071709 12 0.146
positive regulation of cellular amine metabolic process GO:0033240 5 0.146
protein ubiquitination GO:0016567 171 0.145
muscle cell development GO:0055001 133 0.144
regulation of system process GO:0044057 200 0.144
cellular metal ion homeostasis GO:0006875 151 0.142
cellular component assembly involved in morphogenesis GO:0010927 139 0.141
locomotory behavior GO:0007626 195 0.140
lung development GO:0030324 164 0.137
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.135
organelle fission GO:0048285 170 0.134
regulation of protein serine threonine kinase activity GO:0071900 157 0.133
kidney development GO:0001822 213 0.132
hemostasis GO:0007599 78 0.132
positive regulation of protein modification process GO:0031401 299 0.131
regulation of purine nucleotide metabolic process GO:1900542 169 0.131
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.130
trunk neural crest cell migration GO:0036484 4 0.129
regulation of cytoplasmic transport GO:1903649 112 0.128
intracellular protein transport GO:0006886 204 0.128
somite development GO:0061053 81 0.124
mammary gland involution GO:0060056 9 0.124
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 17 0.122
cytoplasmic transport GO:0016482 234 0.122
regulation of response to wounding GO:1903034 189 0.119
skeletal system morphogenesis GO:0048705 203 0.118
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.118
protein localization to organelle GO:0033365 185 0.117
establishment or maintenance of cell polarity GO:0007163 86 0.117
tissue remodeling GO:0048771 102 0.117
positive regulation of muscle cell differentiation GO:0051149 39 0.116
endothelial cell proliferation GO:0001935 27 0.115
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.115
glial cell differentiation GO:0010001 131 0.115
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.114
myofibril assembly GO:0030239 34 0.114
protein modification by small protein conjugation GO:0032446 187 0.113
negative regulation of phosphate metabolic process GO:0045936 184 0.112
negative regulation of cell fate specification GO:0009996 4 0.111
multicellular organism growth GO:0035264 161 0.111
syncytium formation GO:0006949 43 0.111
cell junction assembly GO:0034329 52 0.110
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.110
regulation of calcium ion transport GO:0051924 69 0.109
coagulation GO:0050817 78 0.109
energy derivation by oxidation of organic compounds GO:0015980 77 0.109
Mouse
receptor mediated endocytosis GO:0006898 51 0.109
positive regulation of lymphocyte activation GO:0051251 140 0.108
cardiac muscle cell differentiation GO:0055007 69 0.107
regulation of mapk cascade GO:0043408 248 0.105
Mouse
response to organic cyclic compound GO:0014070 198 0.105
regulation of transferase activity GO:0051338 263 0.105
ear morphogenesis GO:0042471 118 0.104
positive regulation of cytoplasmic transport GO:1903651 40 0.103
appendage development GO:0048736 166 0.102
regulation of calcium ion transport into cytosol GO:0010522 31 0.102
regulation of stress activated mapk cascade GO:0032872 69 0.101
regulation of fatty acid metabolic process GO:0019217 28 0.101
regulation of organelle organization GO:0033043 289 0.101
lateral line system development GO:0048925 1 0.100
epidermis development GO:0008544 187 0.100
apoptotic signaling pathway GO:0097190 306 0.100
protein kinase b signaling GO:0043491 74 0.100
Mouse
negative regulation of endocytosis GO:0045806 12 0.100
positive regulation of myotube differentiation GO:0010831 24 0.099
intrinsic apoptotic signaling pathway GO:0097193 132 0.099
multicellular organismal reproductive behavior GO:0033057 23 0.099
male gamete generation GO:0048232 285 0.099
regulation of epithelial cell proliferation GO:0050678 141 0.098
regulation of protein binding GO:0043393 60 0.096
peptidyl amino acid modification GO:0018193 336 0.096
negative regulation of monooxygenase activity GO:0032769 3 0.095
multi organism behavior GO:0051705 62 0.095
cytokine mediated signaling pathway GO:0019221 115 0.095
anoikis GO:0043276 6 0.095
endocytosis GO:0006897 168 0.094
cytosolic calcium ion homeostasis GO:0051480 70 0.093
central nervous system vasculogenesis GO:0022009 3 0.091
positive regulation of calcium ion transport GO:0051928 27 0.091
positive regulation of cell substrate adhesion GO:0010811 47 0.091
morphogenesis of embryonic epithelium GO:0016331 159 0.091
multicellular organismal homeostasis GO:0048871 164 0.091
nucleobase containing small molecule metabolic process GO:0055086 352 0.091
muscle cell cellular homeostasis GO:0046716 12 0.090
regulation of ion transport GO:0043269 215 0.090
epithelial cell proliferation GO:0050673 174 0.090
regulation of membrane potential GO:0042391 192 0.090
regulation of wnt signaling pathway GO:0030111 123 0.089
single organism cell adhesion GO:0098602 156 0.088
t cell activation GO:0042110 289 0.087
epithelial cell morphogenesis GO:0003382 41 0.087
cell junction organization GO:0034330 77 0.085
negative regulation of response to cytokine stimulus GO:0060761 9 0.084
ossification GO:0001503 216 0.084
cytosolic calcium ion transport GO:0060401 48 0.084
regulation of vesicle mediated transport GO:0060627 139 0.083
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.083
regulation of binding GO:0051098 111 0.082
respiratory tube development GO:0030323 167 0.082
positive regulation of cell development GO:0010720 237 0.082
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.082
neuroepithelial cell differentiation GO:0060563 37 0.082
bone development GO:0060348 120 0.080
negative regulation of cellular protein metabolic process GO:0032269 247 0.080
morphogenesis of a branching structure GO:0001763 203 0.079
regulation of monooxygenase activity GO:0032768 7 0.078
lipid transport GO:0006869 98 0.078
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.077
nitric oxide metabolic process GO:0046209 25 0.077
sensory organ morphogenesis GO:0090596 242 0.076
divalent metal ion transport GO:0070838 172 0.076
skeletal system development GO:0001501 356 0.076
forebrain development GO:0030900 302 0.076
positive regulation of cell adhesion GO:0045785 80 0.076
cellular response to hormone stimulus GO:0032870 150 0.076
negative regulation of endothelial cell proliferation GO:0001937 8 0.074
regulation of endocytosis GO:0030100 69 0.074
regulation of vasoconstriction GO:0019229 14 0.073
negative regulation of protein modification process GO:0031400 163 0.073
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.073
purine containing compound metabolic process GO:0072521 311 0.073
stem cell development GO:0048864 219 0.073
cardiac septum development GO:0003279 59 0.072
single organismal cell cell adhesion GO:0016337 131 0.072
positive regulation of protein kinase activity GO:0045860 144 0.070
positive regulation of t cell activation GO:0050870 101 0.070
regulation of actin filament based process GO:0032970 99 0.070
divalent inorganic cation homeostasis GO:0072507 138 0.070
negative regulation of nitric oxide biosynthetic process GO:0045019 3 0.070
reproductive behavior GO:0019098 32 0.069
negative regulation of protein metabolic process GO:0051248 282 0.068
carbohydrate homeostasis GO:0033500 128 0.068
regulation of muscle adaptation GO:0043502 31 0.068
regulation of protein localization GO:0032880 231 0.067
trabecula formation GO:0060343 24 0.067
response to alkaloid GO:0043279 34 0.067
cellular calcium ion homeostasis GO:0006874 119 0.067
regulation of blood circulation GO:1903522 93 0.067
leukocyte differentiation GO:0002521 342 0.066
negative regulation of muscle hypertrophy GO:0014741 9 0.065
regulation of peptidyl serine phosphorylation GO:0033135 39 0.064
sarcomere organization GO:0045214 24 0.064
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.063
mammary gland epithelium development GO:0061180 65 0.063
embryonic organ morphogenesis GO:0048562 276 0.063
positive regulation of epithelial cell proliferation GO:0050679 68 0.063
negative regulation of phosphorylation GO:0042326 166 0.062
cellular divalent inorganic cation homeostasis GO:0072503 127 0.062
protein localization to nucleus GO:0034504 121 0.062
trabecula morphogenesis GO:0061383 40 0.062
cell maturation GO:0048469 127 0.062
regulation of angiogenesis GO:0045765 81 0.061
monocarboxylic acid metabolic process GO:0032787 191 0.061
glycerolipid metabolic process GO:0046486 122 0.061
multi organism reproductive behavior GO:0044705 29 0.060
lipid homeostasis GO:0055088 63 0.060
elastic fiber assembly GO:0048251 4 0.060
ear development GO:0043583 200 0.060
organelle assembly GO:0070925 177 0.060
cellular ketone metabolic process GO:0042180 84 0.059
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.059
negative regulation of synapse assembly GO:0051964 3 0.059
regulation of stem cell proliferation GO:0072091 78 0.059
ameboidal type cell migration GO:0001667 128 0.059
cation transport GO:0006812 399 0.058
positive regulation of apoptotic process GO:0043065 217 0.058
response to oxygen radical GO:0000305 16 0.058
single organism nuclear import GO:1902593 95 0.058
membrane raft organization GO:0031579 5 0.057
regulation of kinase activity GO:0043549 249 0.056
response to decreased oxygen levels GO:0036293 59 0.056
lipid storage GO:0019915 36 0.055
calcium ion homeostasis GO:0055074 127 0.055
regulation of cell shape GO:0008360 39 0.055
segmentation GO:0035282 93 0.055
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.054
calcium ion transport GO:0006816 159 0.054
appendage morphogenesis GO:0035107 149 0.054
response to organonitrogen compound GO:0010243 246 0.053
lactation GO:0007595 25 0.053
stem cell differentiation GO:0048863 268 0.053
response to hypoxia GO:0001666 58 0.052
nephron tubule morphogenesis GO:0072078 68 0.052
renal tubule morphogenesis GO:0061333 72 0.052
lens development in camera type eye GO:0002088 62 0.051
actin filament bundle assembly GO:0051017 40 0.051
negative regulation of intracellular signal transduction GO:1902532 167 0.051
Mouse
cation homeostasis GO:0055080 212 0.051
regulation of lymphocyte activation GO:0051249 240 0.051
syncytium formation by plasma membrane fusion GO:0000768 42 0.050
establishment of protein localization to organelle GO:0072594 118 0.050
regulation of apoptotic signaling pathway GO:2001233 197 0.050
cell growth GO:0016049 130 0.050
response to peptide hormone GO:0043434 127 0.050
cellular response to hyperoxia GO:0071455 1 0.049
hormone secretion GO:0046879 128 0.049
gonad development GO:0008406 141 0.049
sympathetic neuron projection guidance GO:0097491 4 0.049
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.048
peptidyl serine phosphorylation GO:0018105 74 0.048
mesonephric tubule development GO:0072164 94 0.048
metal ion homeostasis GO:0055065 189 0.048
body fluid secretion GO:0007589 53 0.048
regulation of tube size GO:0035150 57 0.048
neural tube development GO:0021915 160 0.048
regulation of protein ubiquitination GO:0031396 52 0.047
positive regulation of hydrolase activity GO:0051345 148 0.047
action potential GO:0001508 78 0.047
nephron epithelium development GO:0072009 92 0.047
hair follicle development GO:0001942 85 0.047
cardiac muscle fiber development GO:0048739 4 0.046
nucleocytoplasmic transport GO:0006913 139 0.046
organ growth GO:0035265 117 0.046
epithelial tube formation GO:0072175 130 0.046
mitotic cell cycle GO:0000278 195 0.046
triglyceride metabolic process GO:0006641 51 0.046
membrane depolarization GO:0051899 64 0.045
nephron epithelium morphogenesis GO:0072088 68 0.045
cell cell junction organization GO:0045216 72 0.045
cellular response to oxidative stress GO:0034599 76 0.045
positive regulation of ion transport GO:0043270 65 0.045
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.045
autonomic nervous system development GO:0048483 43 0.044
protein homooligomerization GO:0051260 43 0.044
cellular ion homeostasis GO:0006873 165 0.044
regulation of the force of heart contraction GO:0002026 17 0.044
sterol homeostasis GO:0055092 45 0.044
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.044
development of primary sexual characteristics GO:0045137 143 0.044
glucose homeostasis GO:0042593 128 0.044
regulation of intracellular protein transport GO:0033157 82 0.044
nuclear transport GO:0051169 139 0.043
ureteric bud development GO:0001657 94 0.043
negative regulation of binding GO:0051100 39 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.043
negative regulation of calcium ion transport GO:0051926 9 0.043
protein catabolic process GO:0030163 221 0.043
regulation of neural precursor cell proliferation GO:2000177 70 0.043
regulation of lipid metabolic process GO:0019216 118 0.043
muscle adaptation GO:0043500 39 0.042
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.042
regulation of extent of cell growth GO:0061387 52 0.042
peptidyl serine modification GO:0018209 83 0.042
negative regulation of protein ubiquitination GO:0031397 19 0.042
lipid localization GO:0010876 126 0.042
cellular response to biotic stimulus GO:0071216 92 0.042
striated muscle myosin thick filament assembly GO:0071688 1 0.042
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.041
limb development GO:0060173 166 0.041
cellular response to cytokine stimulus GO:0071345 189 0.041
cellular homeostasis GO:0019725 240 0.041
purine nucleotide metabolic process GO:0006163 302 0.041
muscle cell fate specification GO:0042694 1 0.041
response to inorganic substance GO:0010035 96 0.041
cell recognition GO:0008037 83 0.040
embryonic limb morphogenesis GO:0030326 126 0.040
outflow tract morphogenesis GO:0003151 53 0.040
regulation of cell cycle GO:0051726 281 0.040
ribonucleoside triphosphate metabolic process GO:0009199 220 0.040
inner ear morphogenesis GO:0042472 101 0.040
negative regulation of immune system process GO:0002683 209 0.040
ventral trunk neural crest cell migration GO:0036486 4 0.040
protein targeting GO:0006605 143 0.039
cholesterol homeostasis GO:0042632 44 0.039
skeletal muscle fiber development GO:0048741 58 0.039
blood coagulation GO:0007596 76 0.039
extracellular matrix organization GO:0030198 147 0.039
cardiac septum morphogenesis GO:0060411 46 0.039
regulation of muscle hypertrophy GO:0014743 13 0.039
positive regulation of glial cell proliferation GO:0060252 4 0.039
vesicle organization GO:0016050 60 0.039
regulation of branching involved in mammary gland duct morphogenesis GO:0060762 6 0.039
developmental cell growth GO:0048588 84 0.039
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.038
negative regulation of map kinase activity GO:0043407 34 0.038
response to estrogen GO:0043627 24 0.038
regulation of cysteine type endopeptidase activity GO:2000116 65 0.038
defense response to virus GO:0051607 68 0.038
peripheral nervous system development GO:0007422 53 0.038
cellular chemical homeostasis GO:0055082 215 0.038
organophosphate biosynthetic process GO:0090407 122 0.038
negative regulation of reactive oxygen species metabolic process GO:2000378 10 0.038
compound eye development GO:0048749 1 0.038
negative regulation of transferase activity GO:0051348 85 0.038
positive regulation of smooth muscle cell migration GO:0014911 4 0.038
positive regulation of cell death GO:0010942 224 0.038
negative regulation of oxidoreductase activity GO:0051354 4 0.038
regulation of neuron projection development GO:0010975 169 0.038
regulation of ossification GO:0030278 112 0.037
actin mediated cell contraction GO:0070252 15 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.037
neural tube formation GO:0001841 108 0.037
response to oxidative stress GO:0006979 123 0.037
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.036
regulation of reproductive process GO:2000241 66 0.036
negative regulation of intracellular transport GO:0032387 38 0.036
regulation of morphogenesis of a branching structure GO:0060688 53 0.036
receptor biosynthetic process GO:0032800 3 0.036
positive regulation of wnt signaling pathway GO:0030177 45 0.035
mesenchymal cell development GO:0014031 93 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
positive regulation of kinase activity GO:0033674 155 0.035
pinocytosis GO:0006907 6 0.035
cellular response to oxygen levels GO:0071453 20 0.035
lung morphogenesis GO:0060425 50 0.035
neuron projection extension GO:1990138 64 0.035
response to superoxide GO:0000303 16 0.035
regulation of cardiac muscle hypertrophy GO:0010611 13 0.034
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.034

Ptrf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
Human
musculoskeletal system disease DOID:17 0 0.059
muscular disease DOID:0080000 0 0.053
muscle tissue disease DOID:66 0 0.053
heart disease DOID:114 0 0.051
cardiovascular system disease DOID:1287 0 0.051
neuromuscular disease DOID:440 0 0.034