IMP

Process View

Mus musculus

25 genes annotated in mouse

nitric oxide biosynthetic process

The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nitric oxide biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nitric oxide biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Nos2	nitric oxide synthase 2, inducible	0.974
Tlr4	toll-like receptor 4	0.931
Nos1	nitric oxide synthase 1, neuronal	0.929
Lepr	leptin receptor	0.928
Lyz2	lysozyme 2	0.881
Ccr2	chemokine (C-C motif) receptor 2	0.848
Tlr2	toll-like receptor 2	0.694
Atxn1	ataxin 1	0.560
H2-D1	histocompatibility 2, D region locus 1	0.537	Mouse
Myd88	myeloid differentiation primary response gene 88	0.490
Vdr	vitamin D receptor	0.429
Cd44	CD44 antigen	0.405
Pparg	peroxisome proliferator activated receptor gamma	0.389
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.386
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.372
Esr1	estrogen receptor 1 (alpha)	0.364	Human
Insr	insulin receptor	0.340	Human
B2m	beta-2 microglobulin	0.339
Ccl2	chemokine (C-C motif) ligand 2	0.320
Ren1	renin 1 structural	0.290
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.259	Mouse
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.249
Lep	leptin	0.193
Mmp9	matrix metallopeptidase 9	0.191
Dmd	dystrophin, muscular dystrophy	0.191
Tgfb1	transforming growth factor, beta 1	0.186
Ar	androgen receptor	0.180
Il10	interleukin 10	0.178
Vhl	von Hippel-Lindau tumor suppressor	0.173
Tnf	tumor necrosis factor	0.169
Pten	phosphatase and tensin homolog	0.168
Ptgs2	prostaglandin-endoperoxide synthase 2	0.167	Rat
Akt1	thymoma viral proto-oncogene 1	0.157	Human
Ptrf	polymerase I and transcript release factor	0.151
Apoe	apolipoprotein E	0.146
Il6	interleukin 6	0.134
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.118
Agtr1a	angiotensin II receptor, type 1a	0.110
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.110
Smad3	MAD homolog 3 (Drosophila)	0.109
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.106	Mouse
Il1a	interleukin 1 alpha	0.101
H2-K1	histocompatibility 2, K1, K region	0.101	Mouse
Cd14	CD14 antigen	0.098
Gzma	granzyme A	0.093
Lif	leukemia inhibitory factor	0.089
Nos3	nitric oxide synthase 3, endothelial cell	0.089
Ncr1	natural cytotoxicity triggering receptor 1	0.086
F9	coagulation factor IX	0.086
Umod	uromodulin	0.081
Ccr5	chemokine (C-C motif) receptor 5	0.081
Socs1	suppressor of cytokine signaling 1	0.072
Gcet2	germinal center expressed transcript 2	0.069
Aoah	acyloxyacyl hydrolase	0.064
H2-Q7	histocompatibility 2, Q region locus 7	0.063
Gzmk	granzyme K	0.060
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.058
Cav1	caveolin 1, caveolae protein	0.058
Pyhin1	pyrin and HIN domain family, member 1	0.056
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.055
Fasl	Fas ligand (TNF superfamily, member 6)	0.053
Msr1	macrophage scavenger receptor 1	0.052
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.051	Mouse
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.049
Lair1	leukocyte-associated Ig-like receptor 1	0.048
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.048
Notch2	Notch gene homolog 2 (Drosophila)	0.046
H2-Q6	histocompatibility 2, Q region locus 6	0.046
Il7r	interleukin 7 receptor	0.046
Saa4	serum amyloid A 4	0.043
Ghr	growth hormone receptor	0.042
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.042
Il1r1	interleukin 1 receptor, type I	0.042
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.041
Plat	plasminogen activator, tissue	0.041
Il2rg	interleukin 2 receptor, gamma chain	0.039
Fpr1	formyl peptide receptor 1	0.039
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.039
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.039
Wt1	Wilms tumor 1 homolog	0.038
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.038
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.037	Mouse
Klra7	killer cell lectin-like receptor, subfamily A, member 7	0.036	Mouse
Socs3	suppressor of cytokine signaling 3	0.036
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.036
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.035
Ccr6	chemokine (C-C motif) receptor 6	0.034
Itgb3	integrin beta 3	0.033
Clec4n	C-type lectin domain family 4, member n	0.032
Slc12a1	solute carrier family 12, member 1	0.032
Hspa8	heat shock protein 8	0.032
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.031
Cp	ceruloplasmin	0.031
Casp12	caspase 12	0.031
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.031
Mat1a	methionine adenosyltransferase I, alpha	0.030
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.029
Thbd	thrombomodulin	0.029
Ccr3	chemokine (C-C motif) receptor 3	0.029
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.028
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.028
Cps1	carbamoyl-phosphate synthetase 1	0.028
Bcar1	breast cancer anti-estrogen resistance 1	0.028
Ncoa3	nuclear receptor coactivator 3	0.028
Col1a1	collagen, type I, alpha 1	0.027
Ahsg	alpha-2-HS-glycoprotein	0.027
Klra3	killer cell lectin-like receptor, subfamily A, member 3	0.027	Mouse
Plau	plasminogen activator, urokinase	0.027
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.027
F7	coagulation factor VII	0.026
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.026
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.026
Ifna1	interferon alpha 1	0.025
Cd300ld	CD300 molecule-like family member d	0.025
Vegfa	vascular endothelial growth factor A	0.025
Slamf8	SLAM family member 8	0.025
Ilk	integrin linked kinase	0.024
Myod1	myogenic differentiation 1	0.024
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.024
Tktl1	transketolase-like 1	0.024
Cblb	Casitas B-lineage lymphoma b	0.024
Ccr1	chemokine (C-C motif) receptor 1	0.023
Gzmb	granzyme B	0.023
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.023
Ldlr	low density lipoprotein receptor	0.022
Havcr2	hepatitis A virus cellular receptor 2	0.022
Col14a1	collagen, type XIV, alpha 1	0.022
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.022
Invs	inversin	0.021
Cxcr6	chemokine (C-X-C motif) receptor 6	0.021
Niacr1	niacin receptor 1	0.021
Mapk14	mitogen-activated protein kinase 14	0.021
Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	0.020
Il12b	interleukin 12b	0.020
Bicc1	bicaudal C homolog 1 (Drosophila)	0.020
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.020
Mas1	MAS1 oncogene	0.019
Cxcl10	chemokine (C-X-C motif) ligand 10	0.019
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.019
Mb	myoglobin	0.019
Hspd1	heat shock protein 1 (chaperonin)	0.019
Hsph1	heat shock 105kDa/110kDa protein 1	0.019
Ccr4	chemokine (C-C motif) receptor 4	0.019
AA408251	expressed sequence AA408251	0.019
Chst3	carbohydrate (chondroitin 6/keratan) sulfotransferase 3	0.018
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.018
Stat3	signal transducer and activator of transcription 3	0.018
Il6st	interleukin 6 signal transducer	0.018
H2-Q8	histocompatibility 2, Q region locus 8	0.018
Itgax	integrin alpha X	0.018
Klra6	killer cell lectin-like receptor, subfamily A, member 6	0.018	Mouse
Vcp	valosin containing protein	0.018
Akr1c6	aldo-keto reductase family 1, member C6	0.018
Arf2	ADP-ribosylation factor 2	0.017
Gnrh1	gonadotropin releasing hormone 1	0.017
Lmna	lamin A	0.017
Fpr3	formyl peptide receptor 3	0.017
Adam23	a disintegrin and metallopeptidase domain 23	0.017
Prlhr	prolactin releasing hormone receptor	0.017
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.017	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.017
Meox2	mesenchyme homeobox 2	0.016
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.016
AF251705	cDNA sequence AF251705	0.016
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.016
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.016
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.016
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.016
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.016
Plek	pleckstrin	0.016
Slamf7	SLAM family member 7	0.016
Cx3cr1	chemokine (C-X3-C) receptor 1	0.016
Prkce	protein kinase C, epsilon	0.016
Tlr6	toll-like receptor 6	0.016	Mouse
Shisa5	shisa homolog 5 (Xenopus laevis)	0.016
Mapkapk2	MAP kinase-activated protein kinase 2	0.015
Klra8	killer cell lectin-like receptor, subfamily A, member 8	0.015
Agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	0.015
Stat1	signal transducer and activator of transcription 1	0.015
Irak4	interleukin-1 receptor-associated kinase 4	0.015
Drd2	dopamine receptor D2	0.015
Saa2	serum amyloid A 2	0.015
Tlr5	toll-like receptor 5	0.015	Mouse
Ccr9	chemokine (C-C motif) receptor 9	0.015
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.015
Idua	iduronidase, alpha-L-	0.015
Ccl4	chemokine (C-C motif) ligand 4	0.015
Casp1	caspase 1	0.015
Omt2b	oocyte maturation, beta	0.015
Adipoq	adiponectin, C1Q and collagen domain containing	0.015
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.015
Klk1b4	kallikrein 1-related pepidase b4	0.014
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.014	Mouse
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.014
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.014
Ly9	lymphocyte antigen 9	0.014
Cd33	CD33 antigen	0.014
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.014
H2-Eb1	histocompatibility 2, class II antigen E beta	0.014
Elf1	E74-like factor 1	0.014
Pnpla2	patatin-like phospholipase domain containing 2	0.014
Npy1r	neuropeptide Y receptor Y1	0.014
Btk	Bruton agammaglobulinemia tyrosine kinase	0.014
Cysltr1	cysteinyl leukotriene receptor 1	0.014
Spp1	secreted phosphoprotein 1	0.014
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.014
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.014
Ifngr1	interferon gamma receptor 1	0.014
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.014
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.014
G6pc	glucose-6-phosphatase, catalytic	0.014
Blk	B lymphoid kinase	0.014
Il10ra	interleukin 10 receptor, alpha	0.014
Tlr1	toll-like receptor 1	0.014	Mouse
Cd300a	CD300A antigen	0.014
Tapbp	TAP binding protein	0.013
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.013
Mup4	major urinary protein 4	0.013
Akt2	thymoma viral proto-oncogene 2	0.013	Rat
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.013
Il13	interleukin 13	0.013
Cytip	cytohesin 1 interacting protein	0.013
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.013
Aqp9	aquaporin 9	0.013
Ptafr	platelet-activating factor receptor	0.013
Olfr16	olfactory receptor 16	0.013
Igf1r	insulin-like growth factor I receptor	0.013
Mcoln2	mucolipin 2	0.013
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.013
Hmox1	heme oxygenase (decycling) 1	0.013
Cxcl13	chemokine (C-X-C motif) ligand 13	0.013
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.013
Olfr49	olfactory receptor 49	0.013
H2-Q10	histocompatibility 2, Q region locus 10	0.013	Mouse
Ccl5	chemokine (C-C motif) ligand 5	0.013
Tdo2	tryptophan 2,3-dioxygenase	0.013
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.013
Dmgdh	dimethylglycine dehydrogenase precursor	0.013
Prnp	prion protein	0.013
Tert	telomerase reverse transcriptase	0.013
Ptgir	prostaglandin I receptor (IP)	0.013
Fosb	FBJ osteosarcoma oncogene B	0.013
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.013
Src	Rous sarcoma oncogene	0.013
Agxt	alanine-glyoxylate aminotransferase	0.012
Hopx	HOP homeobox	0.012
Prdm1	PR domain containing 1, with ZNF domain	0.012
Cldn1	claudin 1	0.012
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.012
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.012
Cd86	CD86 antigen	0.012
Vnn3	vanin 3	0.012
Aplp2	amyloid beta (A4) precursor-like protein 2	0.012
Ccl3	chemokine (C-C motif) ligand 3	0.012
Il18rap	interleukin 18 receptor accessory protein	0.012
Fcrla	Fc receptor-like A	0.012
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.012
Il7	interleukin 7	0.012
Itga2	integrin alpha 2	0.012
Klrb1a	killer cell lectin-like receptor subfamily B member 1A	0.012
Kynu	kynureninase (L-kynurenine hydrolase)	0.012
Sykb	spleen tyrosine kinase	0.012
Nppb	natriuretic peptide type B	0.012
Ctsw	cathepsin W	0.012
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.012
Ifngr2	interferon gamma receptor 2	0.012
Cxcl9	chemokine (C-X-C motif) ligand 9	0.012
Glrp1	glutamine repeat protein 1	0.012
Klre1	killer cell lectin-like receptor family E member 1	0.012	Mouse
Ptgs1	prostaglandin-endoperoxide synthase 1	0.012
Cys1	cystin 1	0.012
Il18r1	interleukin 18 receptor 1	0.012
Itga4	integrin alpha 4	0.012
Cd84	CD84 antigen	0.012
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.012
Grb10	growth factor receptor bound protein 10	0.012
Sox17	SRY-box containing gene 17	0.012
Unc93b1	unc-93 homolog B1 (C. elegans)	0.012
Orm2	orosomucoid 2	0.012
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.012
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.012
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.012
C4b	complement component 4B (Childo blood group)	0.012
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.012
Stat6	signal transducer and activator of transcription 6	0.011
C9	complement component 9	0.011
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.011
Clcn5	chloride channel 5	0.011
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.011
Csprs	component of Sp100-rs	0.011
Mapkap1	mitogen-activated protein kinase associated protein 1	0.011
H2-Q5	histocompatibility 2, Q region locus 5	0.011
Cd7	CD7 antigen	0.011
Il2ra	interleukin 2 receptor, alpha chain	0.011
Gpr18	G protein-coupled receptor 18	0.011
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.011
Nt5e	5' nucleotidase, ecto	0.011
Maged1	melanoma antigen, family D, 1	0.011
Ciita	class II transactivator	0.011
Fcgr4	Fc receptor, IgG, low affinity IV	0.011
Klc1	kinesin light chain 1	0.011
Il1rl1	interleukin 1 receptor-like 1	0.011
Slfn1	schlafen 1	0.011
Timp4	tissue inhibitor of metalloproteinase 4	0.011
Cd80	CD80 antigen	0.011
Olfr2	olfactory receptor 2	0.011
Kcnk6	potassium inwardly-rectifying channel, subfamily K, member 6	0.011
H2-M2	histocompatibility 2, M region locus 2	0.011
Dnase1l3	deoxyribonuclease 1-like 3	0.011
Prlr	prolactin receptor	0.011
Tcfec	transcription factor EC	0.011
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.011
Car5a	carbonic anhydrase 5a, mitochondrial	0.011
C2	complement component 2 (within H-2S)	0.011
Ahr	aryl-hydrocarbon receptor	0.010
Lgals8	lectin, galactose binding, soluble 8	0.010
Cybb	cytochrome b-245, beta polypeptide	0.010
Il15	interleukin 15	0.010
Selp	selectin, platelet	0.010
Npy2r	neuropeptide Y receptor Y2	0.010
Fpr2	formyl peptide receptor 2	0.010
Csf1	colony stimulating factor 1 (macrophage)	0.010
F10	coagulation factor X	0.010
Traf1	TNF receptor-associated factor 1	0.010
Ptgfrn	prostaglandin F2 receptor negative regulator	0.010
Hgf	hepatocyte growth factor	0.010
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.010
Axl	AXL receptor tyrosine kinase	0.010
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.010
Fyb	FYN binding protein	0.010
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.010
Cd36	CD36 antigen	0.010
Trpv1	transient receptor potential cation channel, subfamily V, member 1	0.010	Rat
Tll1	tolloid-like	0.010