|
|
negative regulation of synaptic transmission glutamatergic
|
GO:0051967 |
4 |
0.999
|
Mouse |
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
48 |
0.990
|
Mouse |
|
|
regulation of excitatory postsynaptic membrane potential
|
GO:0060079 |
41 |
0.989
|
Mouse |
|
|
membrane hyperpolarization
|
GO:0060081 |
21 |
0.987
|
Mouse |
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.982
|
Mouse |
|
|
ionotropic glutamate receptor signaling pathway
|
GO:0035235 |
29 |
0.943
|
Human Mouse Worm |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.902
|
|
|
|
directional locomotion
|
GO:0033058 |
3 |
0.868
|
Worm |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.844
|
Human Mouse Worm |
|
|
regulation of synaptic transmission glutamatergic
|
GO:0051966 |
19 |
0.825
|
Mouse |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.823
|
|
|
|
glutamate receptor signaling pathway
|
GO:0007215 |
35 |
0.809
|
Human Mouse Worm |
|
|
fear response
|
GO:0042596 |
33 |
0.790
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.773
|
Human Mouse Worm |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.762
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.756
|
Mouse |
|
|
regulation of glutamate receptor signaling pathway
|
GO:1900449 |
16 |
0.755
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.745
|
|
|
|
synaptic transmission glutamatergic
|
GO:0035249 |
36 |
0.731
|
Mouse Worm |
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.703
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.651
|
Mouse |
|
|
neuron neuron synaptic transmission
|
GO:0007270 |
69 |
0.651
|
Mouse Worm |
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.645
|
Mouse |
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.644
|
Mouse |
|
|
memory
|
GO:0007613 |
58 |
0.609
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.599
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.581
|
Mouse |
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.581
|
Mouse |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.578
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.573
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.557
|
Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.534
|
Mouse |
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.529
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.517
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.510
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.483
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.469
|
|
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.466
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.459
|
Mouse |
|
|
behavioral fear response
|
GO:0001662 |
28 |
0.442
|
Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.437
|
|
|
|
receptor recycling
|
GO:0001881 |
11 |
0.419
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.417
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.414
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.413
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.399
|
Mouse |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.398
|
Mouse |
|
|
long term synaptic depression
|
GO:0060292 |
13 |
0.395
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.381
|
|
|
|
axonal fasciculation
|
GO:0007413 |
15 |
0.380
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.377
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.369
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.355
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.339
|
|
|
|
sensory perception of bitter taste
|
GO:0050913 |
6 |
0.339
|
Worm |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.330
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.304
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.296
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.290
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.290
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.288
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.286
|
Mouse |
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.281
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.281
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.278
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.267
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.264
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.256
|
Mouse |
|
|
lateral line system development
|
GO:0048925 |
1 |
0.254
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.252
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.251
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.245
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.244
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.231
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.220
|
Mouse |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.218
|
|
|
|
regulation of sensory perception of pain
|
GO:0051930 |
8 |
0.216
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.216
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.215
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.212
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.210
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.209
|
Worm |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.209
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.209
|
Mouse |
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.204
|
|
|
|
regulation of receptor recycling
|
GO:0001919 |
8 |
0.198
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.195
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.194
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.188
|
|
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.186
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.181
|
Mouse |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.180
|
|
|
|
regulation of inhibitory postsynaptic membrane potential
|
GO:0060080 |
13 |
0.179
|
Mouse |
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.159
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.157
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.155
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.154
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.154
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.153
|
Mouse |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.149
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.148
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.145
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.145
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.144
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.144
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.143
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.142
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.142
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.138
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.138
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.137
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.137
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.137
|
|
|
|
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity
|
GO:2000311 |
11 |
0.136
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.135
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.135
|
|
|
|
regulation of n methyl d aspartate selective glutamate receptor activity
|
GO:2000310 |
10 |
0.132
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.131
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.131
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.129
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.129
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.128
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.124
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.123
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.123
|
Worm |
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.122
|
Worm |
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.122
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.121
|
Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.120
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.120
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.120
|
|
|
|
adult walking behavior
|
GO:0007628 |
41 |
0.119
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.119
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.119
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.116
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.115
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.114
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.112
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.111
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.110
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.109
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.109
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.108
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.107
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.107
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.107
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.107
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.104
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.104
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.103
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.103
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.102
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.101
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.101
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.101
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.100
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.100
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.100
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.099
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.098
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.097
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.097
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.097
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.096
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.094
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.093
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.093
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.092
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.092
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.090
|
|
|
|
receptor internalization
|
GO:0031623 |
16 |
0.089
|
|
|
|
dendritic spine development
|
GO:0060996 |
30 |
0.089
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.088
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.088
|
|
|
|
regulation of short term neuronal synaptic plasticity
|
GO:0048172 |
8 |
0.088
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.088
|
Mouse |
|
|
acid secretion
|
GO:0046717 |
33 |
0.087
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.086
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.086
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.086
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.085
|
|
|
|
cellular response to temperature stimulus
|
GO:0071502 |
2 |
0.084
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.084
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.084
|
|
|
|
positive regulation of long term neuronal synaptic plasticity
|
GO:0048170 |
3 |
0.084
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.083
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.082
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.081
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.081
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.080
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.080
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.079
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.078
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.073
|
|
|
|
positive regulation of heart rate by epinephrine norepinephrine
|
GO:0001996 |
4 |
0.073
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.073
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.072
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.072
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.071
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.071
|
|
|
|
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure
|
GO:0002025 |
3 |
0.071
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.070
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.070
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.070
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.069
|
|
|
|
negative regulation of adenylate cyclase activity
|
GO:0007194 |
1 |
0.068
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.068
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.067
|
|
|
|
sa node cell action potential
|
GO:0086015 |
4 |
0.066
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.066
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.064
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.064
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.064
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.063
|
|
|
|
membrane depolarization during sa node cell action potential
|
GO:0086046 |
2 |
0.063
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.063
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.063
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.062
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.061
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.061
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.061
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.061
|
|
|
|
regulation of response to drug
|
GO:2001023 |
2 |
0.061
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.061
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.061
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.061
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.061
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.061
|
|
|
|
cellular response to ammonium ion
|
GO:0071242 |
2 |
0.061
|
|
|
|
mitochondrion transport along microtubule
|
GO:0047497 |
3 |
0.060
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.060
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.060
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.060
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.059
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.059
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.059
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.059
|
|
|
|
response to histamine
|
GO:0034776 |
1 |
0.059
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.058
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.058
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.058
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.058
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.058
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.058
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.058
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.057
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.056
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.056
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.056
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.056
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.056
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.056
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.056
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.055
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.055
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.055
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.054
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.054
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.054
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.053
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.053
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.053
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.053
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.053
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.053
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.053
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.053
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.052
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.052
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.051
|
|
|
|
positive regulation of synaptic transmission gabaergic
|
GO:0032230 |
8 |
0.051
|
|
|
|
positive regulation of membrane potential
|
GO:0045838 |
15 |
0.051
|
|
|
|
protein tetramerization
|
GO:0051262 |
23 |
0.051
|
|
|
|
regulation of the force of heart contraction
|
GO:0002026 |
17 |
0.051
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.051
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.050
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.050
|
|
|
|
cerebral cortex gabaergic interneuron development
|
GO:0021894 |
6 |
0.050
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.050
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.050
|
|
|
|
regulation of striated muscle contraction
|
GO:0006942 |
25 |
0.049
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.049
|
|
|
|
regulation of dendritic spine morphogenesis
|
GO:0061001 |
17 |
0.048
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.048
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.048
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.048
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.048
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.048
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.048
|
|
|
|
adrenergic receptor signaling pathway
|
GO:0071875 |
13 |
0.048
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.047
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.047
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.047
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.047
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.047
|
|
|
|
regulation of heart rate
|
GO:0002027 |
36 |
0.047
|
|
|
|
positive regulation of excitatory postsynaptic membrane potential
|
GO:2000463 |
14 |
0.047
|
|
|
|
fasciculation of sensory neuron axon
|
GO:0097155 |
3 |
0.047
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.046
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.046
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.046
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.046
|
Mouse |
|
|
regulation of sensory perception
|
GO:0051931 |
8 |
0.046
|
|
|
|
cellular response to histamine
|
GO:0071420 |
1 |
0.046
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.046
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.046
|
|
|
|
establishment of glial blood brain barrier
|
GO:0060857 |
2 |
0.045
|
|
|
|
fasciculation of motor neuron axon
|
GO:0097156 |
2 |
0.045
|
|
|
|
synaptic vesicle fusion to presynaptic membrane
|
GO:0031629 |
3 |
0.045
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.044
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.044
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.044
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.044
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
4 |
0.044
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.044
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
22 |
0.043
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.043
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.043
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.043
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.043
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.043
|
|
|
|
response to amphetamine
|
GO:0001975 |
16 |
0.043
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.042
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.042
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.042
|
|
|
|
histamine induced gastric acid secretion
|
GO:0001697 |
1 |
0.042
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.042
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.042
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.042
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.042
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.041
|
|
|
|
substrate independent telencephalic tangential migration
|
GO:0021826 |
8 |
0.041
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.041
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.041
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.041
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.041
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.041
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.040
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.040
|
|
|
|
cerebral cortex gabaergic interneuron differentiation
|
GO:0021892 |
9 |
0.040
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.040
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.039
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.039
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.039
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.039
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.039
|
|
|
|
behavioral defense response
|
GO:0002209 |
28 |
0.039
|
Mouse |
|
|
dorsal ventral axon guidance
|
GO:0033563 |
3 |
0.038
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.038
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.038
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.038
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.038
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.038
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.038
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.037
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
29 |
0.037
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.037
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.037
|
|
|
|
response to amine
|
GO:0014075 |
16 |
0.036
|
|
|
|
notochord cell development
|
GO:0060035 |
1 |
0.036
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.036
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.036
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway in response to osmotic stress
|
GO:0008627 |
2 |
0.036
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.036
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.036
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.036
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.036
|
|
|
|
synaptic transmission glycinergic
|
GO:0060012 |
2 |
0.036
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.036
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.035
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.035
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
13 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.035
|
|
|
|
regulation of neurological system process
|
GO:0031644 |
22 |
0.035
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.035
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
13 |
0.035
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.035
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.035
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.034
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.034
|
|
|
|
sensory perception of taste
|
GO:0050909 |
18 |
0.034
|
Worm |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.034
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.034
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.034
|
|
|
|
positive regulation of striated muscle contraction
|
GO:0045989 |
3 |
0.034
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.034
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.034
|
|
|
|
dopamine receptor signaling pathway
|
GO:0007212 |
16 |
0.034
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.034
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.034
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.034
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.034
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.033
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.033
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.033
|
|
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.032
|
|
|
|
vasodilation
|
GO:0042311 |
28 |
0.032
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
5 |
0.032
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.032
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.032
|
|
|
|
anion transmembrane transport
|
GO:0098656 |
71 |
0.032
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.032
|
|
|
|
neuron maturation
|
GO:0042551 |
29 |
0.032
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.031
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.031
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
22 |
0.031
|
|
|
|
positive regulation of the force of heart contraction by chemical signal
|
GO:0003099 |
3 |
0.031
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
21 |
0.031
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.031
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
28 |
0.031
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.031
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.031
|
|
|
|
regulation of long term synaptic potentiation
|
GO:1900271 |
4 |
0.031
|
|
|
|
neurotransmitter gated ion channel clustering
|
GO:0072578 |
6 |
0.031
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.031
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.031
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.031
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.031
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.030
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.030
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.030
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.030
|
|
|
|
anatomical structure maturation
|
GO:0071695 |
49 |
0.030
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.030
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.030
|
|
|
|
regulation of systemic arterial blood pressure by norepinephrine epinephrine
|
GO:0001993 |
8 |
0.030
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.030
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.030
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.030
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.029
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.029
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.029
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.029
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.029
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.029
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.029
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.029
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.029
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.029
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.029
|
|
|
|
positive regulation of the force of heart contraction by epinephrine norepinephrine
|
GO:0001997 |
3 |
0.029
|
|
|
|
reflex
|
GO:0060004 |
22 |
0.028
|
|
|
|
cerebral cortex gabaergic interneuron migration
|
GO:0021853 |
6 |
0.028
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
4 |
0.028
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.028
|
|
|
|
male courtship behavior
|
GO:0008049 |
2 |
0.028
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.028
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.028
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.028
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
29 |
0.028
|
|
|
|
positive regulation of high voltage gated calcium channel activity
|
GO:1901843 |
1 |
0.028
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.027
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.027
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.027
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.027
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.027
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.027
|
|
|
|
catecholamine transport
|
GO:0051937 |
21 |
0.026
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.026
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.026
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.026
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.026
|
|
|
|
regulation of renin secretion into blood stream
|
GO:1900133 |
4 |
0.026
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.026
|
|
|
|
regulation of urine volume
|
GO:0035809 |
6 |
0.026
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.026
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.026
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.026
|
|
|
|
exploration behavior
|
GO:0035640 |
21 |
0.026
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.026
|
|
|
|
cerebellar cortex formation
|
GO:0021697 |
22 |
0.026
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.026
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.025
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
3 |
0.025
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.025
|
|
|
|
gamma aminobutyric acid secretion
|
GO:0014051 |
6 |
0.025
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.025
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.025
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.025
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.025
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.025
|
|
|
|
gonadotrophin releasing hormone neuronal migration to the hypothalamus
|
GO:0021828 |
3 |
0.025
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.025
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.024
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.024
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.024
|
|
|
|
negative regulation of lyase activity
|
GO:0051350 |
1 |
0.024
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.024
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.024
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.024
|
|
