IMP

Process View

Mus musculus

3 genes annotated in mouse

synaptic vesicle fusion to presynaptic membrane

Fusion of the membrane of a synaptic vesicle with its target presynaptic membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "synaptic vesicle fusion to presynaptic membrane"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "synaptic vesicle fusion to presynaptic membrane" (in gray)

Name	Description	Probability	Func Analog Organism
Vamp2	vesicle-associated membrane protein 2	0.998
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.985
Stx1a	syntaxin 1A (brain)	0.952	Fly
Snap25	synaptosomal-associated protein 25	0.902	Fly
Dlg4	discs, large homolog 4 (Drosophila)	0.834
Syt2	synaptotagmin II	0.527
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.401
Grik2	glutamate receptor, ionotropic, kainate 2 (beta 2)	0.394
Syp	synaptophysin	0.307
Clstn1	calsyntenin 1	0.274
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.223
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.215
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.197
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.196
Stxbp1	syntaxin binding protein 1	0.184
Arc	activity regulated cytoskeletal-associated protein	0.156
Rusc1	RUN and SH3 domain containing 1	0.141
Ina	internexin neuronal intermediate filament protein, alpha	0.124
Dlg2	discs, large homolog 2 (Drosophila)	0.115
Htt	huntingtin	0.115
Mapk10	mitogen-activated protein kinase 10	0.095
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.090
Shank2	SH3/ankyrin domain gene 2	0.077
Dnm1	dynamin 1	0.074
Dlg3	discs, large homolog 3 (Drosophila)	0.065
Syt1	synaptotagmin I	0.059
Bsn	bassoon	0.057
Mtap2	microtubule-associated protein 2	0.056
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.054
Emx1	empty spiracles homolog 1 (Drosophila)	0.051
Stxbp5	syntaxin binding protein 5 (tomosyn)	0.051
Gnao1	guanine nucleotide binding protein, alpha O	0.051
Cdh8	cadherin 8	0.047
Homer1	homer homolog 1 (Drosophila)	0.046
Nefl	neurofilament, light polypeptide	0.046
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.045
Calb1	calbindin 1	0.042
Klc2	kinesin light chain 2	0.041
Resp18	regulated endocrine-specific protein 18	0.040
Scn1a	sodium channel, voltage-gated, type I, alpha	0.038
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.036
Ikbkb	inhibitor of kappaB kinase beta	0.035
Prkar2b	protein kinase, cAMP dependent regulatory, type II beta	0.031
Dsg1a	desmoglein 1 alpha	0.030
Dcx	doublecortin	0.030
Kifc2	kinesin family member C2	0.029
Nrg3	neuregulin 3	0.029
Tmod3	tropomodulin 3	0.028
Prkce	protein kinase C, epsilon	0.027
Ccdc64b	coiled-coil domain containing 64B	0.026
Kif5c	kinesin family member 5C	0.024
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.023
Kalrn	kalirin, RhoGEF kinase	0.023
Nefm	neurofilament, medium polypeptide	0.023
Snca	synuclein, alpha	0.023
Scg5	secretogranin V	0.022
Cit	citron	0.022
Rps6ka3	ribosomal protein S6 kinase polypeptide 3	0.021
Myh10	myosin, heavy polypeptide 10, non-muscle	0.021
Fgf12	fibroblast growth factor 12	0.020
Scn8a	sodium channel, voltage-gated, type VIII, alpha	0.020
Gdap1	ganglioside-induced differentiation-associated-protein 1	0.020
Chga	chromogranin A	0.020
Adcy1	adenylate cyclase 1	0.020
C78859	expressed sequence C78859	0.020
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.020
Ctnna2	catenin (cadherin associated protein), alpha 2	0.019
L1cam	L1 cell adhesion molecule	0.019
Rph3al	rabphilin 3A-like (without C2 domains)	0.019
Ptpn9	protein tyrosine phosphatase, non-receptor type 9	0.019
Cux2	cut-like homeobox 2	0.019
Nsf	N-ethylmaleimide sensitive fusion protein	0.018	Fly
Rab3a	RAB3A, member RAS oncogene family	0.018
Syngr1	synaptogyrin 1	0.018
Nrsn1	neurensin 1	0.018
Cnih2	cornichon homolog 2 (Drosophila)	0.018
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.017
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.016
Mapk3	mitogen-activated protein kinase 3	0.016
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.016
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.015
Scg3	secretogranin III	0.015
Epha5	Eph receptor A5	0.015
BC018242	cDNA sequence BC018242	0.015
Kif1a	kinesin family member 1A	0.015
Gap43	growth associated protein 43	0.015
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.015
Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	0.015
Ppp1r1a	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.014
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.014
Stmn3	stathmin-like 3	0.014
Src	Rous sarcoma oncogene	0.014
Nos1	nitric oxide synthase 1, neuronal	0.014
Prkcb	protein kinase C, beta	0.014
Lin7b	lin-7 homolog B (C. elegans)	0.014
Cltc	clathrin, heavy polypeptide (Hc)	0.013
Syt5	synaptotagmin V	0.013
Rasgrf1	RAS protein-specific guanine nucleotide-releasing factor 1	0.013
Mtap6	microtubule-associated protein 6	0.013
Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor	0.013
Cntn3	contactin 3	0.013
Fxyd7	FXYD domain-containing ion transport regulator 7	0.012
Rp2h	retinitis pigmentosa 2 homolog (human)	0.012
Tubb4	tubulin, beta 4	0.012
Grm1	glutamate receptor, metabotropic 1	0.012
St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.012
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.012
Palm	paralemmin	0.012
Gnaz	guanine nucleotide binding protein, alpha z subunit	0.012
Scg2	secretogranin II	0.011
Ptprn	protein tyrosine phosphatase, receptor type, N	0.011
Cabp7	calcium binding protein 7	0.011
Ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.011
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.011
Slc7a14	solute carrier family 7 (cationic amino acid transporter, y+ system), member 14	0.011
Cttn	cortactin	0.011
Actl6b	actin-like 6B	0.011
Pfkl	phosphofructokinase, liver, B-type	0.011
Hpca	hippocalcin	0.011
Neurod6	neurogenic differentiation 6	0.011
Ly96	lymphocyte antigen 96	0.011
Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	0.011
Nxph1	neurexophilin 1	0.011
Golph3l	golgi phosphoprotein 3-like	0.011
Trhr	thyrotropin releasing hormone receptor	0.010
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.010
Dtx3	deltex 3 homolog (Drosophila)	0.010
Mog	myelin oligodendrocyte glycoprotein	0.010
Tuba4a	tubulin, alpha 4A	0.010
Cyp46a1	cytochrome P450, family 46, subfamily a, polypeptide 1	0.010
Pde6d	phosphodiesterase 6D, cGMP-specific, rod, delta	0.010
Kcna6	potassium voltage-gated channel, shaker-related, subfamily, member 6	0.010