Mus musculus

59 known processes

Klhl10

kelch-like 10 (Drosophila)

(Aliases: 4921517C11Rik)

Klhl10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis GO:0007283 284 0.143
cellular ketone metabolic process GO:0042180 84 0.101
cellular amino acid metabolic process GO:0006520 103 0.095
male gamete generation GO:0048232 285 0.094
cellular amine metabolic process GO:0044106 44 0.082
regulation of cellular amino acid metabolic process GO:0006521 5 0.075
germ cell development GO:0007281 185 0.072
regulation of cellular ketone metabolic process GO:0010565 66 0.068
spermatid development GO:0007286 108 0.066
nucleoside phosphate metabolic process GO:0006753 338 0.052
male meiosis GO:0007140 37 0.052
negative regulation of phosphate metabolic process GO:0045936 184 0.045
positive regulation of programmed cell death GO:0043068 218 0.045
negative regulation of phosphorylation GO:0042326 166 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.044
organonitrogen compound catabolic process GO:1901565 264 0.041
peptidyl amino acid modification GO:0018193 336 0.040
amine metabolic process GO:0009308 45 0.040
extracellular structure organization GO:0043062 148 0.039
regulation of cell cycle GO:0051726 281 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
organelle assembly GO:0070925 177 0.035
purine containing compound metabolic process GO:0072521 311 0.034
positive regulation of cell death GO:0010942 224 0.034
nitrogen compound transport GO:0071705 271 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
cellular lipid metabolic process GO:0044255 323 0.033
amide transport GO:0042886 138 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
regulation of organelle organization GO:0033043 289 0.032
actin cytoskeleton organization GO:0030036 220 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
spermatid differentiation GO:0048515 115 0.030
asymmetric stem cell division GO:0098722 3 0.030
camera type eye development GO:0043010 266 0.030
macromolecule catabolic process GO:0009057 281 0.029
oxidation reduction process GO:0055114 342 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
renal system development GO:0072001 225 0.029
negative regulation of intracellular signal transduction GO:1902532 167 0.029
Mouse
protein catabolic process GO:0030163 221 0.028
organic anion transport GO:0015711 137 0.028
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
extracellular matrix organization GO:0030198 147 0.027
heterocycle catabolic process GO:0046700 280 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
cellular chemical homeostasis GO:0055082 215 0.027
regulation of cell cycle process GO:0010564 160 0.026
rho protein signal transduction GO:0007266 32 0.026
ras protein signal transduction GO:0007265 77 0.026
nucleoside metabolic process GO:0009116 246 0.026
response to organonitrogen compound GO:0010243 246 0.026
regulation of cell projection organization GO:0031344 206 0.026
glycosyl compound metabolic process GO:1901657 246 0.025
regionalization GO:0003002 337 0.025
leukocyte differentiation GO:0002521 342 0.025
meiosis i GO:0007127 60 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
purine containing compound catabolic process GO:0072523 213 0.025
synaptic transmission GO:0007268 329 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
organophosphate catabolic process GO:0046434 232 0.024
immune effector process GO:0002252 321 0.024
regulation of secretion GO:0051046 274 0.024
cell type specific apoptotic process GO:0097285 268 0.023
nucleoside phosphate catabolic process GO:1901292 222 0.023
cellular protein catabolic process GO:0044257 155 0.023
carbohydrate metabolic process GO:0005975 230 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
protein ubiquitination GO:0016567 171 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
positive regulation of protein modification process GO:0031401 299 0.022
chromatin modification GO:0016568 187 0.022
embryonic organ morphogenesis GO:0048562 276 0.022
regulation of hydrolase activity GO:0051336 246 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
lipid biosynthetic process GO:0008610 179 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
cellular homeostasis GO:0019725 240 0.022
organelle fission GO:0048285 170 0.022
cell adhesion GO:0007155 329 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
apoptotic signaling pathway GO:0097190 306 0.021
Mouse
regulation of secretion by cell GO:1903530 249 0.021
mapk cascade GO:0000165 281 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
regulation of cellular response to stress GO:0080135 159 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
adult behavior GO:0030534 135 0.021
Mouse
ribose phosphate metabolic process GO:0019693 291 0.020
positive regulation of organelle organization GO:0010638 128 0.020
methylation GO:0032259 134 0.020
positive regulation of apoptotic signaling pathway GO:2001235 95 0.020
ion transmembrane transport GO:0034220 361 0.020
covalent chromatin modification GO:0016569 163 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
sensory organ morphogenesis GO:0090596 242 0.020
dna metabolic process GO:0006259 303 0.019
regulation of ion transport GO:0043269 215 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
stem cell differentiation GO:0048863 268 0.019
cytoplasmic transport GO:0016482 234 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
blastocyst development GO:0001824 80 0.019
t cell activation GO:0042110 289 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
regulation of protein localization GO:0032880 231 0.019
urogenital system development GO:0001655 261 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
regulation of transferase activity GO:0051338 263 0.018
male meiosis i GO:0007141 16 0.018
small molecule biosynthetic process GO:0044283 132 0.018
oviduct development GO:0060066 3 0.018
skeletal system morphogenesis GO:0048705 203 0.018
carbohydrate biosynthetic process GO:0016051 74 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
peptide transport GO:0015833 133 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
macromolecule methylation GO:0043414 120 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of nucleoside metabolic process GO:0009118 130 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
transmembrane transport GO:0055085 412 0.018
digestive system development GO:0055123 200 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.018
response to amino acid GO:0043200 37 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
sensory perception GO:0007600 245 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
muscle cell differentiation GO:0042692 261 0.018
regulation of system process GO:0044057 200 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
dendrite development GO:0016358 115 0.017
Mouse
metal ion homeostasis GO:0055065 189 0.017
rna interference GO:0016246 2 0.017
inflammatory response GO:0006954 244 0.017
nucleotide catabolic process GO:0009166 217 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
aromatic compound catabolic process GO:0019439 286 0.017
negative regulation of molecular function GO:0044092 258 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
chromatin organization GO:0006325 206 0.017
hexose metabolic process GO:0019318 98 0.017
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.017
positive regulation of cell projection organization GO:0031346 95 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
nuclear transport GO:0051169 139 0.017
mitotic cell cycle GO:0000278 195 0.017
regulation of mapk cascade GO:0043408 248 0.017
carboxylic acid transport GO:0046942 100 0.017
histone modification GO:0016570 159 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.016
cell division GO:0051301 120 0.016
multi multicellular organism process GO:0044706 109 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
Mouse
purine nucleoside catabolic process GO:0006152 205 0.016
cation homeostasis GO:0055080 212 0.016
nuclear division GO:0000280 158 0.016
adult locomotory behavior GO:0008344 91 0.016
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.016
membrane organization GO:0061024 245 0.016
positive regulation of neuron projection development GO:0010976 79 0.016
protein localization to organelle GO:0033365 185 0.016
positive regulation of nervous system development GO:0051962 221 0.016
glycoprotein metabolic process GO:0009100 116 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
regulation of actin filament based process GO:0032970 99 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
cilium morphogenesis GO:0060271 102 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
microtubule based process GO:0007017 236 0.015
photoreceptor cell development GO:0042461 40 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
regulation of response to wounding GO:1903034 189 0.015
neuron death GO:0070997 154 0.015
positive regulation of kinase activity GO:0033674 155 0.015
dna methylation involved in gamete generation GO:0043046 15 0.015
cell maturation GO:0048469 127 0.015
pirna metabolic process GO:0034587 12 0.015
gonad development GO:0008406 141 0.015
glucose homeostasis GO:0042593 128 0.015
synapsis GO:0007129 34 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
maintenance of location GO:0051235 89 0.015
lipid localization GO:0010876 126 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
Mouse
calcium ion homeostasis GO:0055074 127 0.015
regulation of establishment of protein localization GO:0070201 181 0.014
mitochondrion organization GO:0007005 134 0.014
regulation of actin cytoskeleton organization GO:0032956 84 0.014
cation transport GO:0006812 399 0.014
vitamin metabolic process GO:0006766 23 0.014
cell substrate adhesion GO:0031589 130 0.014
t cell proliferation GO:0042098 120 0.014
intracellular protein transport GO:0006886 204 0.014
insulin secretion GO:0030073 89 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
negative regulation of protein modification process GO:0031400 163 0.014
blood vessel morphogenesis GO:0048514 285 0.014
regulation of t cell activation GO:0050863 170 0.014
regulation of glucose metabolic process GO:0010906 60 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
muscle tissue development GO:0060537 308 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
rna processing GO:0006396 105 0.014
regulation of cell activation GO:0050865 289 0.014
physiological cardiac muscle hypertrophy GO:0003301 3 0.014
chromosome organization involved in meiosis GO:0070192 39 0.014
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.014
regulation of protein kinase activity GO:0045859 232 0.014
androgen biosynthetic process GO:0006702 4 0.014
glycerolipid metabolic process GO:0046486 122 0.014
physiological muscle hypertrophy GO:0003298 3 0.014
regulation of hormone levels GO:0010817 211 0.013
hormone secretion GO:0046879 128 0.013
oocyte axis specification GO:0007309 2 0.013
alcohol metabolic process GO:0006066 116 0.013
regulation of cell adhesion GO:0030155 154 0.013
learning or memory GO:0007611 148 0.013
gastrulation GO:0007369 116 0.013
response to organic cyclic compound GO:0014070 198 0.013
protein targeting GO:0006605 143 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
response to drug GO:0042493 75 0.013
development of primary sexual characteristics GO:0045137 143 0.013
response to radiation GO:0009314 165 0.013
response to monosaccharide GO:0034284 67 0.013
nucleotide metabolic process GO:0009117 332 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
organic hydroxy compound transport GO:0015850 93 0.013
anion transport GO:0006820 177 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
meiotic cell cycle process GO:1903046 77 0.013
regulation of proteolysis GO:0030162 164 0.013
stem cell maintenance GO:0019827 130 0.013
stem cell development GO:0048864 219 0.013
cell recognition GO:0008037 83 0.013
fat cell differentiation GO:0045444 160 0.013
cofactor transport GO:0051181 4 0.013
axonogenesis GO:0007409 274 0.013
peptide secretion GO:0002790 114 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
negative regulation of cell cycle GO:0045786 123 0.013
dna recombination GO:0006310 92 0.013
positive regulation of cell development GO:0010720 237 0.013
germ line stem cell division GO:0042078 2 0.013
response to acid chemical GO:0001101 111 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
retina development in camera type eye GO:0060041 119 0.013
cell growth involved in cardiac muscle cell development GO:0061049 3 0.013
cerebellum development GO:0021549 77 0.013
Mouse
regulation of intracellular transport GO:0032386 159 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
rac protein signal transduction GO:0016601 13 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
epidermis development GO:0008544 187 0.012
Mouse
b cell activation GO:0042113 161 0.012
striated muscle tissue development GO:0014706 293 0.012
ossification GO:0001503 216 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
monosaccharide metabolic process GO:0005996 106 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
Mouse
negative regulation of transposition GO:0010529 2 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
kidney development GO:0001822 213 0.012
telencephalon development GO:0021537 186 0.012
organic acid transport GO:0015849 101 0.012
development of primary male sexual characteristics GO:0046546 88 0.012
anatomical structure homeostasis GO:0060249 145 0.012
endocytosis GO:0006897 168 0.012
placenta development GO:0001890 140 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
interleukin 8 production GO:0032637 4 0.012
glucose metabolic process GO:0006006 92 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
cellularization GO:0007349 1 0.012
cellular response to peptide GO:1901653 92 0.012
regulation of cardiac muscle tissue development GO:0055024 31 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
male sex differentiation GO:0046661 109 0.012
intracellular mrna localization GO:0008298 4 0.012
blood circulation GO:0008015 195 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
compound eye development GO:0048749 1 0.012
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.012
multicellular organism growth GO:0035264 161 0.012
protein maturation GO:0051604 176 0.011
lymphocyte proliferation GO:0046651 164 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
response to oxidative stress GO:0006979 123 0.011
dna modification GO:0006304 50 0.011
exocytosis GO:0006887 121 0.011
female sex differentiation GO:0046660 84 0.011
embryonic appendage morphogenesis GO:0035113 126 0.011
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.011
synapse organization GO:0050808 125 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
meiotic cell cycle GO:0051321 122 0.011
epithelial cell development GO:0002064 159 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
lymphocyte differentiation GO:0030098 242 0.011
respiratory system development GO:0060541 190 0.011
nephron development GO:0072006 109 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
steroid metabolic process GO:0008202 119 0.011
regulation of peptide transport GO:0090087 91 0.011
mitotic cell cycle process GO:1903047 159 0.011
mrna metabolic process GO:0016071 84 0.011
bone development GO:0060348 120 0.011
regulation of neuron death GO:1901214 134 0.011
gtp catabolic process GO:0006184 143 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
male germ line stem cell asymmetric division GO:0048133 2 0.011
negative regulation of cell development GO:0010721 169 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
directional locomotion GO:0033058 3 0.011
negative regulation of organelle organization GO:0010639 90 0.011
heterochromatin organization GO:0070828 4 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.010
regulation of synaptic plasticity GO:0048167 87 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
photoreceptor cell morphogenesis GO:0008594 3 0.010
muscle adaptation GO:0043500 39 0.010
peptide hormone secretion GO:0030072 109 0.010
bundle of his development GO:0003166 4 0.010
neuron apoptotic process GO:0051402 142 0.010
regulation of peptide hormone secretion GO:0090276 75 0.010
photoreceptor cell differentiation GO:0046530 52 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
regulation of mitotic cell cycle phase transition GO:1901990 73 0.010
myeloid cell differentiation GO:0030099 233 0.010
positive regulation of protein transport GO:0051222 93 0.010
asymmetric neuroblast division GO:0055059 1 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
neural precursor cell proliferation GO:0061351 121 0.010
cellular response to amino acid stimulus GO:0071230 29 0.010
cellular ion homeostasis GO:0006873 165 0.010
rap protein signal transduction GO:0032486 3 0.010
negative regulation of kinase activity GO:0033673 81 0.010
stem cell proliferation GO:0072089 117 0.010
protein processing GO:0016485 163 0.010
lateral inhibition GO:0046331 1 0.010
male gonad development GO:0008584 88 0.010
epithelial tube morphogenesis GO:0060562 303 0.010

Klhl10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
musculoskeletal system disease DOID:17 0 0.030
bone disease DOID:0080001 0 0.019
connective tissue disease DOID:65 0 0.019
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.016
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012