IMP

Process View

Mus musculus

2 genes annotated in mouse

male germ line stem cell asymmetric division

The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "male germ line stem cell asymmetric division"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "male germ line stem cell asymmetric division" (in gray)

Name	Description	Probability	Func Analog Organism
Irs2	insulin receptor substrate 2	0.937	Fly
Grb10	growth factor receptor bound protein 10	0.886
Insr	insulin receptor	0.874	Fly
Ghr	growth hormone receptor	0.533
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.236
Hrh1	histamine receptor H1	0.170
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.156
Irs1	insulin receptor substrate 1	0.142	Fly
Igf2r	insulin-like growth factor 2 receptor	0.136
Zfp592	zinc finger protein 592	0.135
Kiss1	KiSS-1 metastasis-suppressor	0.134
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.117
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.083
Igf2	insulin-like growth factor 2	0.071
Ins2	insulin II	0.068
Cav1	caveolin 1, caveolae protein	0.061
Piwil2	piwi-like homolog 2 (Drosophila)	0.060	Fly
Lipe	lipase, hormone sensitive	0.058
Pnpla2	patatin-like phospholipase domain containing 2	0.055
Drd2	dopamine receptor D2	0.050
Sik3	SIK family kinase 3	0.044
Pparg	peroxisome proliferator activated receptor gamma	0.042
Mark2	MAP/microtubule affinity-regulating kinase 2	0.042
Thra	thyroid hormone receptor alpha	0.042
Tsx	testis specific X-linked gene	0.040
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.039
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.039
Esr1	estrogen receptor 1 (alpha)	0.032
Tex14	testis expressed gene 14	0.031
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.031
Ar	androgen receptor	0.031
Kiss1r	KISS1 receptor	0.030
Igf1r	insulin-like growth factor I receptor	0.030	Fly
Lep	leptin	0.030
Klf13	Kruppel-like factor 13	0.028
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.028
Tcam1	testicular cell adhesion molecule 1	0.027
Neo1	neogenin	0.025
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.024
Foxf1a	forkhead box F1a	0.024
Hoxa13	homeobox A13	0.023
Map3k6	mitogen-activated protein kinase kinase kinase 6	0.022
Rest	RE1-silencing transcription factor	0.022
Zfhx3	zinc finger homeobox 3	0.021
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.021
Il12rb1	interleukin 12 receptor, beta 1	0.021
Brd4	bromodomain containing 4	0.020
Med13l	mediator complex subunit 13-like	0.020
Sim1	single-minded homolog 1 (Drosophila)	0.020
Mael	maelstrom homolog (Drosophila)	0.020
Hoxa10	homeobox A10	0.020
Tcf23	transcription factor 23	0.019
Irf2bp2	interferon regulatory factor 2 binding protein 2	0.019
Cdh23	cadherin 23 (otocadherin)	0.019
Adipoq	adiponectin, C1Q and collagen domain containing	0.018
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.018
Amhr2	anti-Mullerian hormone type 2 receptor	0.017
Nos3	nitric oxide synthase 3, endothelial cell	0.017
Amdhd1	amidohydrolase domain containing 1	0.017
H1f0	H1 histone family, member 0	0.017
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.017
Plin4	perilipin 4	0.016
Wwc2	WW, C2 and coiled-coil domain containing 2	0.015
Klf7	Kruppel-like factor 7 (ubiquitous)	0.015
Wfikkn1	WAP, FS, Ig, KU, and NTR-containing protein 1	0.015
Npc1	Niemann Pick type C1	0.015
Fgf21	fibroblast growth factor 21	0.014
Trp53bp2	transformation related protein 53 binding protein 2	0.014
Fabp9	fatty acid binding protein 9, testis	0.013
Nhlh2	nescient helix loop helix 2	0.013
Defb3	defensin beta 3	0.013
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.013
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.013
Rsph6a	radial spoke head 6 homolog A (Chlamydomonas)	0.013
Smc1b	structural maintenance of chromosomes 1B	0.013
Per1	period homolog 1 (Drosophila)	0.013
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.012
Lhx3	LIM homeobox protein 3	0.012
Enah	enabled homolog (Drosophila)	0.012
Angpt4	angiopoietin 4	0.012
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.012
Lpin1	lipin 1	0.012
Nfia	nuclear factor I/A	0.011
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.011
4933407C03Rik	RIKEN cDNA 4933407C03 gene	0.011
Fzd4	frizzled homolog 4 (Drosophila)	0.011
Klf3	Kruppel-like factor 3 (basic)	0.011
Zbtb7a	zinc finger and BTB domain containing 7a	0.011
Hoxd11	homeobox D11	0.011
Prok2	prokineticin 2	0.011
Tcfl5	transcription factor-like 5 (basic helix-loop-helix)	0.011
Sorbs1	sorbin and SH3 domain containing 1	0.011
Rhox6	reproductive homeobox 6	0.011
Ell	elongation factor RNA polymerase II	0.011
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.011
Krtcap3	keratinocyte associated protein 3	0.011
Adcy9	adenylate cyclase 9	0.011
H1fnt	H1 histone family, member N, testis-specific	0.011
Klhl10	kelch-like 10 (Drosophila)	0.011
Pim3	proviral integration site 3	0.011
Fkbp5	FK506 binding protein 5	0.010
Csnk1e	casein kinase 1, epsilon	0.010
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.010
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.010
Hoxa11	homeobox A11	0.010
Pbx1	pre B-cell leukemia transcription factor 1	0.010
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.010