Mus musculus

376 known processes

Pml

promyelocytic leukemia

(Aliases: Trim19,1200009E24Rik,AI661194)

Pml biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stem cell development GO:0048864 219 0.536
myelination in peripheral nervous system GO:0022011 19 0.500
stem cell differentiation GO:0048863 268 0.456
protein modification by small protein conjugation or removal GO:0070647 207 0.455
Human
negative regulation of multi organism process GO:0043901 68 0.418
positive regulation of apoptotic signaling pathway GO:2001235 95 0.406
viral process GO:0016032 41 0.405
schwann cell development GO:0014044 22 0.371
cellular response to growth factor stimulus GO:0071363 197 0.371
protein catabolic process GO:0030163 221 0.347
Human
extrinsic apoptotic signaling pathway GO:0097191 126 0.298
epithelial tube morphogenesis GO:0060562 303 0.287
muscle cell development GO:0055001 133 0.285
embryonic epithelial tube formation GO:0001838 130 0.282
chromatin organization GO:0006325 206 0.280
Human
forebrain development GO:0030900 302 0.275
negative regulation of molecular function GO:0044092 258 0.275
Human
negative regulation of cell proliferation GO:0008285 296 0.266
positive regulation of apoptotic process GO:0043065 217 0.264
stem cell maintenance GO:0019827 130 0.262
protein oligomerization GO:0051259 67 0.243
chromatin modification GO:0016568 187 0.241
Human
blastocyst development GO:0001824 80 0.237
regulation of apoptotic signaling pathway GO:2001233 197 0.234
regulation of membrane potential GO:0042391 192 0.233
negative regulation of protein metabolic process GO:0051248 282 0.220
Human
regulation of cytokine production GO:0001817 266 0.215
dna metabolic process GO:0006259 303 0.213
Human
histone modification GO:0016570 159 0.213
Human
positive regulation of programmed cell death GO:0043068 218 0.211
regulation of defense response GO:0031347 233 0.211
Human
positive regulation of kinase activity GO:0033674 155 0.205
activation of immune response GO:0002253 138 0.195
neural tube development GO:0021915 160 0.192
protein modification by small protein conjugation GO:0032446 187 0.185
Human
innate immune response GO:0045087 157 0.179
cytoplasmic transport GO:0016482 234 0.179
epithelial tube formation GO:0072175 130 0.179
cell fate commitment GO:0045165 210 0.179
muscle fiber development GO:0048747 76 0.179
tube formation GO:0035148 140 0.177
germ cell development GO:0007281 185 0.176
morphogenesis of embryonic epithelium GO:0016331 159 0.175
modification dependent macromolecule catabolic process GO:0043632 133 0.174
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.173
Human
ras protein signal transduction GO:0007265 77 0.166
blastocyst formation GO:0001825 33 0.164
muscle tissue development GO:0060537 308 0.158
regulation of multi organism process GO:0043900 111 0.158
negative regulation of cellular component organization GO:0051129 194 0.153
Human
neural tube formation GO:0001841 108 0.150
protein homotrimerization GO:0070207 4 0.149
positive regulation of protein phosphorylation GO:0001934 242 0.146
b cell activation GO:0042113 161 0.145
multicellular organismal signaling GO:0035637 91 0.139
regulation of kinase activity GO:0043549 249 0.137
negative regulation of organelle organization GO:0010639 90 0.134
Human
response to growth factor GO:0070848 198 0.134
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.131
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.127
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.126
Human
homeostasis of number of cells GO:0048872 210 0.124
positive regulation of cell death GO:0010942 224 0.123
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.121
regulation of innate immune response GO:0045088 91 0.121
myeloid cell differentiation GO:0030099 233 0.121
appendage morphogenesis GO:0035107 149 0.120
positive regulation of cytokine production GO:0001819 174 0.119
positive regulation of mapk cascade GO:0043410 170 0.117
cellular protein catabolic process GO:0044257 155 0.117
Human
positive regulation of peptidase activity GO:0010952 49 0.117
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.116
intracellular receptor signaling pathway GO:0030522 74 0.114
pattern recognition receptor signaling pathway GO:0002221 47 0.113
immune response activating signal transduction GO:0002757 116 0.113
covalent chromatin modification GO:0016569 163 0.113
Human
interspecies interaction between organisms GO:0044419 83 0.112
protein localization to organelle GO:0033365 185 0.112
regulation of protein complex assembly GO:0043254 83 0.111
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.110
respiratory system development GO:0060541 190 0.110
defense response to other organism GO:0098542 197 0.108
Human
primary neural tube formation GO:0014020 95 0.108
tube closure GO:0060606 91 0.105
regulation of cellular amino acid metabolic process GO:0006521 5 0.104
regulation of defense response to virus GO:0050688 18 0.103
Human
cellular amino acid metabolic process GO:0006520 103 0.101
response to transforming growth factor beta GO:0071559 88 0.101
neural tube closure GO:0001843 90 0.101
positive regulation of protein kinase activity GO:0045860 144 0.100
regulation of transferase activity GO:0051338 263 0.100
Human
myeloid cell homeostasis GO:0002262 114 0.100
regulation of intracellular transport GO:0032386 159 0.100
negative regulation of viral process GO:0048525 23 0.099
striated muscle tissue development GO:0014706 293 0.097
cellular response to dna damage stimulus GO:0006974 207 0.097
telencephalon development GO:0021537 186 0.097
negative regulation of protein modification process GO:0031400 163 0.096
Human
limb morphogenesis GO:0035108 149 0.095
myotube differentiation GO:0014902 105 0.094
cellular response to lipid GO:0071396 145 0.093
mitotic cell cycle GO:0000278 195 0.092
regulation of cellular amine metabolic process GO:0033238 20 0.091
negative regulation of cellular protein metabolic process GO:0032269 247 0.090
Human
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.090
immune response regulating signaling pathway GO:0002764 125 0.089
small gtpase mediated signal transduction GO:0007264 97 0.089
regulation of protein catabolic process GO:0042176 108 0.089
Human
purine ribonucleotide metabolic process GO:0009150 290 0.089
regulation of protein deacetylation GO:0090311 17 0.088
Human
olfactory bulb development GO:0021772 30 0.088
positive regulation of nervous system development GO:0051962 221 0.086
regulation of chromatin modification GO:1903308 57 0.086
Human
regulation of chromosome organization GO:0033044 83 0.086
Human
olfactory lobe development GO:0021988 32 0.086
regulation of organelle organization GO:0033043 289 0.086
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.085
glial cell development GO:0021782 54 0.084
ribonucleoside triphosphate metabolic process GO:0009199 220 0.083
peptidyl amino acid modification GO:0018193 336 0.082
aromatic compound catabolic process GO:0019439 286 0.082
skeletal muscle fiber development GO:0048741 58 0.081
glial cell differentiation GO:0010001 131 0.081
regulation of cellular component biogenesis GO:0044087 181 0.081
regulation of hydrolase activity GO:0051336 246 0.080
appendage development GO:0048736 166 0.080
positive regulation of transferase activity GO:0051347 167 0.079
viral life cycle GO:0019058 36 0.079
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.079
regulation of cell projection organization GO:0031344 206 0.078
muscle cell differentiation GO:0042692 261 0.078
lymphocyte homeostasis GO:0002260 64 0.076
striated muscle cell development GO:0055002 125 0.076
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.076
hematopoietic progenitor cell differentiation GO:0002244 143 0.076
nucleoside catabolic process GO:0009164 206 0.075
transmission of nerve impulse GO:0019226 76 0.075
somatic stem cell maintenance GO:0035019 47 0.074
carbohydrate derivative catabolic process GO:1901136 231 0.074
regionalization GO:0003002 337 0.073
positive regulation of innate immune response GO:0045089 80 0.072
regulation of proteolysis GO:0030162 164 0.071
regulation of peptidase activity GO:0052547 96 0.071
protein homooligomerization GO:0051260 43 0.070
regulation of mapk cascade GO:0043408 248 0.070
organic cyclic compound catabolic process GO:1901361 295 0.069
camera type eye development GO:0043010 266 0.069
ensheathment of neurons GO:0007272 76 0.069
negative regulation of phosphorylation GO:0042326 166 0.069
purine nucleoside triphosphate metabolic process GO:0009144 226 0.068
regulation of binding GO:0051098 111 0.068
regulation of cell motility GO:2000145 236 0.067
sensory organ morphogenesis GO:0090596 242 0.067
myotube cell development GO:0014904 60 0.067
regulation of cellular response to stress GO:0080135 159 0.066
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.066
activation of innate immune response GO:0002218 56 0.066
regulation of endopeptidase activity GO:0052548 89 0.065
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.065
nucleotide metabolic process GO:0009117 332 0.065
negative regulation of nervous system development GO:0051961 156 0.064
neuron death GO:0070997 154 0.064
establishment of protein localization to organelle GO:0072594 118 0.063
negative regulation of protein phosphorylation GO:0001933 126 0.063
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.063
production of molecular mediator of immune response GO:0002440 103 0.062
cell adhesion GO:0007155 329 0.062
positive regulation of hydrolase activity GO:0051345 148 0.062
immune effector process GO:0002252 321 0.061
Human
regulation of protein transport GO:0051223 163 0.061
b cell activation involved in immune response GO:0002312 50 0.061
limb development GO:0060173 166 0.061
gland development GO:0048732 330 0.061
development of primary sexual characteristics GO:0045137 143 0.061
skeletal system development GO:0001501 356 0.061
glycosyl compound metabolic process GO:1901657 246 0.060
purine ribonucleoside catabolic process GO:0046130 205 0.060
purine ribonucleotide catabolic process GO:0009154 208 0.060
protein import into nucleus GO:0006606 95 0.059
leukocyte differentiation GO:0002521 342 0.059
regulation of cellular ketone metabolic process GO:0010565 66 0.059
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.058
action potential GO:0001508 78 0.058
negative regulation of intracellular signal transduction GO:1902532 167 0.058
negative regulation of chromatin modification GO:1903309 19 0.058
regulation of neuron differentiation GO:0045664 281 0.057
positive regulation of cellular component biogenesis GO:0044089 94 0.057
cellular macromolecule catabolic process GO:0044265 206 0.057
Human
cellular amine metabolic process GO:0044106 44 0.057
organonitrogen compound catabolic process GO:1901565 264 0.056
schwann cell differentiation GO:0014037 26 0.056
cellular nitrogen compound catabolic process GO:0044270 280 0.056
cytokine production GO:0001816 319 0.056
leukocyte homeostasis GO:0001776 79 0.055
purine nucleoside metabolic process GO:0042278 241 0.055
palate development GO:0060021 76 0.054
embryonic limb morphogenesis GO:0030326 126 0.054
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.054
cellular response to type i interferon GO:0071357 10 0.054
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.053
dna conformation change GO:0071103 37 0.052
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.052
purine nucleoside catabolic process GO:0006152 205 0.052
stress activated mapk cascade GO:0051403 80 0.052
regulation of neuron death GO:1901214 134 0.052
regulation of interferon beta production GO:0032648 13 0.052
protein processing GO:0016485 163 0.051
regulation of actin cytoskeleton organization GO:0032956 84 0.051
bone development GO:0060348 120 0.051
retina development in camera type eye GO:0060041 119 0.051
protein localization to nucleus GO:0034504 121 0.051
nucleoside monophosphate metabolic process GO:0009123 85 0.051
response to radiation GO:0009314 165 0.051
lens morphogenesis in camera type eye GO:0002089 24 0.050
negative regulation of cellular amine metabolic process GO:0033239 1 0.050
mitotic cytokinesis GO:0000281 4 0.050
head morphogenesis GO:0060323 34 0.050
regulation of establishment of protein localization GO:0070201 181 0.050
microtubule cytoskeleton organization GO:0000226 157 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.049
Human
lens development in camera type eye GO:0002088 62 0.049
regulation of protein kinase activity GO:0045859 232 0.049
anatomical structure homeostasis GO:0060249 145 0.049
Human
positive regulation of cell development GO:0010720 237 0.048
Human
nose development GO:0043584 12 0.048
programmed necrotic cell death GO:0097300 28 0.048
macromolecule catabolic process GO:0009057 281 0.048
Human
nucleotide catabolic process GO:0009166 217 0.048
positive regulation of type i interferon production GO:0032481 14 0.048
skeletal system morphogenesis GO:0048705 203 0.047
bone resorption GO:0045453 38 0.047
regulation of cellular catabolic process GO:0031329 242 0.047
Human
peptidyl serine modification GO:0018209 83 0.047
histone deacetylation GO:0016575 26 0.047
Human
positive regulation of proteolysis GO:0045862 85 0.047
apoptotic signaling pathway GO:0097190 306 0.047
positive regulation of interferon alpha production GO:0032727 4 0.047
skin development GO:0043588 220 0.046
heterocycle catabolic process GO:0046700 280 0.046
intrinsic apoptotic signaling pathway GO:0097193 132 0.045
response to interferon gamma GO:0034341 34 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.045
lymphocyte differentiation GO:0030098 242 0.045
response to lipopolysaccharide GO:0032496 128 0.045
atp catabolic process GO:0006200 55 0.045
positive regulation of organelle organization GO:0010638 128 0.044
Human
peripheral nervous system development GO:0007422 53 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.043
cellular protein complex assembly GO:0043623 116 0.043
ubiquitin dependent protein catabolic process GO:0006511 129 0.043
Human
positive regulation of cell projection organization GO:0031346 95 0.043
protein trimerization GO:0070206 13 0.042
positive regulation of neuron projection development GO:0010976 79 0.042
viral genome replication GO:0019079 17 0.042
positive regulation of neuron death GO:1901216 28 0.042
protein import GO:0017038 101 0.041
regulation of protein binding GO:0043393 60 0.041
negative regulation of synapse assembly GO:0051964 3 0.041
positive regulation of defense response GO:0031349 124 0.041
positive regulation of protein modification process GO:0031401 299 0.041
Human
negative regulation of immune system process GO:0002683 209 0.041
nucleoside metabolic process GO:0009116 246 0.040
proteasomal protein catabolic process GO:0010498 98 0.040
Human
nucleoside phosphate catabolic process GO:1901292 222 0.040
epithelial cell proliferation GO:0050673 174 0.040
positive regulation of protein complex assembly GO:0031334 45 0.040
membrane organization GO:0061024 245 0.040
gene silencing by mirna GO:0035195 10 0.040
negative regulation of bmp signaling pathway GO:0030514 35 0.039
embryonic appendage morphogenesis GO:0035113 126 0.039
cellular response to lipopolysaccharide GO:0071222 77 0.039
regulation of cellular response to growth factor stimulus GO:0090287 82 0.039
protein heterooligomerization GO:0051291 14 0.039
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.039
response to organonitrogen compound GO:0010243 246 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
axon ensheathment GO:0008366 76 0.038
defense response to virus GO:0051607 68 0.038
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
ossification GO:0001503 216 0.038
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.038
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.038
protein maturation GO:0051604 176 0.038
sensory perception GO:0007600 245 0.037
regulation of response to wounding GO:1903034 189 0.037
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.037
protein ubiquitination GO:0016567 171 0.037
Human
cell maturation GO:0048469 127 0.037
organophosphate catabolic process GO:0046434 232 0.037
epidermis development GO:0008544 187 0.037
digestive tract development GO:0048565 190 0.037
endocytosis GO:0006897 168 0.037
regulation of cell migration GO:0030334 219 0.037
blood vessel morphogenesis GO:0048514 285 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.036
carbohydrate metabolic process GO:0005975 230 0.036
mammary gland epithelium development GO:0061180 65 0.036
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.036
atp metabolic process GO:0046034 75 0.036
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.036
protein polyubiquitination GO:0000209 33 0.036
face morphogenesis GO:0060325 29 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
amine metabolic process GO:0009308 45 0.035
negative regulation of viral genome replication GO:0045071 10 0.035
body morphogenesis GO:0010171 45 0.035
ribonucleoside monophosphate metabolic process GO:0009161 80 0.035
gliogenesis GO:0042063 141 0.035
wnt signaling pathway GO:0016055 188 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
response to type i interferon GO:0034340 12 0.035
positive regulation of neuron differentiation GO:0045666 141 0.034
lipid localization GO:0010876 126 0.034
multicellular organismal homeostasis GO:0048871 164 0.034
skeletal muscle organ development GO:0060538 163 0.033
negative regulation of kinase activity GO:0033673 81 0.033
cellular ketone metabolic process GO:0042180 84 0.033
purine containing compound metabolic process GO:0072521 311 0.033
macromolecule deacylation GO:0098732 37 0.033
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
transmembrane transport GO:0055085 412 0.033
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
keratinocyte differentiation GO:0030216 48 0.032
regulation of actin nucleation GO:0051125 4 0.032
regulation of striated muscle cell differentiation GO:0051153 81 0.032
cellular response to biotic stimulus GO:0071216 92 0.032
digestive system development GO:0055123 200 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.032
divalent inorganic cation transport GO:0072511 178 0.032
regulation of protein localization GO:0032880 231 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
posttranscriptional regulation of gene expression GO:0010608 155 0.031
Human
axonogenesis GO:0007409 274 0.031
innate immune response activating signal transduction GO:0002758 50 0.031
negative regulation of cell development GO:0010721 169 0.031
dendrite development GO:0016358 115 0.030
regulation of leukocyte differentiation GO:1902105 159 0.030
rho protein signal transduction GO:0007266 32 0.030
regulation of cytoskeleton organization GO:0051493 122 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.030
spermatid differentiation GO:0048515 115 0.030
leukocyte mediated immunity GO:0002443 174 0.030
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.030
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 14 0.030
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.030
glycosyl compound catabolic process GO:1901658 206 0.029
negative regulation of transferase activity GO:0051348 85 0.029
Human
rhythmic process GO:0048511 174 0.029
modification dependent protein catabolic process GO:0019941 133 0.029
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
apoptotic mitochondrial changes GO:0008637 48 0.029
negative regulation of histone modification GO:0031057 18 0.029
immunoglobulin production GO:0002377 73 0.029
meiotic cell cycle GO:0051321 122 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.028
release of cytochrome c from mitochondria GO:0001836 23 0.028
cell type specific apoptotic process GO:0097285 268 0.028
necrotic cell death GO:0070265 30 0.028
erythrocyte differentiation GO:0030218 88 0.028
regulation of t cell activation GO:0050863 170 0.028
histone h3 acetylation GO:0043966 14 0.028
adaptive immune response GO:0002250 155 0.028
interferon beta production GO:0032608 16 0.028
negative regulation of viral transcription GO:0032897 3 0.028
regulation of cellular component size GO:0032535 121 0.028
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
actin filament polymerization GO:0030041 44 0.028
mesenchyme development GO:0060485 152 0.028
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.027
pallium development GO:0021543 120 0.027
androgen receptor signaling pathway GO:0030521 8 0.027
regulation of response to biotic stimulus GO:0002831 38 0.027
Human
positive regulation of growth GO:0045927 104 0.027
positive regulation of binding GO:0051099 49 0.027
female sex differentiation GO:0046660 84 0.027
i kappab kinase nf kappab signaling GO:0007249 85 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
regulation of necroptotic process GO:0060544 10 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
regulation of ossification GO:0030278 112 0.027
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.027
macromolecule methylation GO:0043414 120 0.026
methylation GO:0032259 134 0.026
nuclear transport GO:0051169 139 0.026
epithelial cell development GO:0002064 159 0.026
negative regulation of cytokine production GO:0001818 84 0.026
bone morphogenesis GO:0060349 78 0.026
actin polymerization or depolymerization GO:0008154 54 0.026
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
response to dsrna GO:0043331 30 0.026
positive regulation of actin nucleation GO:0051127 3 0.026
wound healing GO:0042060 157 0.026
apical constriction GO:0003383 4 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.025
viral gene expression GO:0019080 3 0.025
cellular lipid metabolic process GO:0044255 323 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
cation homeostasis GO:0055080 212 0.025
regulation of interferon beta biosynthetic process GO:0045357 4 0.025
regulation of toll like receptor signaling pathway GO:0034121 20 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
nuclear import GO:0051170 95 0.025
male gamete generation GO:0048232 285 0.025
toll like receptor signaling pathway GO:0002224 38 0.025
response to light stimulus GO:0009416 135 0.024
regulation of actin polymerization or depolymerization GO:0008064 45 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
er nucleus signaling pathway GO:0006984 27 0.024
t cell proliferation GO:0042098 120 0.024
response to antibiotic GO:0046677 11 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
microtubule based process GO:0007017 236 0.024
type i interferon signaling pathway GO:0060337 10 0.024
leukocyte proliferation GO:0070661 172 0.024
cellular homeostasis GO:0019725 240 0.024
negative regulation of histone deacetylation GO:0031064 2 0.023
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.023
negative regulation of growth GO:0045926 99 0.023
Human
cellular response to molecule of bacterial origin GO:0071219 83 0.023
interaction with host GO:0051701 22 0.023
citrate metabolic process GO:0006101 3 0.023
inflammatory response GO:0006954 244 0.023
lymphocyte proliferation GO:0046651 164 0.023
regulation of bmp signaling pathway GO:0030510 60 0.023
regulation of actin filament polymerization GO:0030833 38 0.022
lymphocyte activation involved in immune response GO:0002285 93 0.022
response to peptide GO:1901652 136 0.022
viral transcription GO:0019083 3 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
bone remodeling GO:0046849 53 0.022
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.022
Human
regulation of chromatin organization GO:1902275 57 0.022
Human
regulation of neuron projection development GO:0010975 169 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
regulation of myeloid cell differentiation GO:0045637 96 0.022
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.022
regulation of osteoblast differentiation GO:0045667 67 0.022
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.022
synapse organization GO:0050808 125 0.022
regulation of homeostatic process GO:0032844 182 0.022
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.022
adult behavior GO:0030534 135 0.022
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.022
establishment of organelle localization GO:0051656 122 0.022
regulation of transporter activity GO:0032409 57 0.022
immunoglobulin mediated immune response GO:0016064 69 0.021
positive regulation of actin filament polymerization GO:0030838 26 0.021
cellularization GO:0007349 1 0.021
protein deacylation GO:0035601 36 0.021
Human
endomembrane system organization GO:0010256 147 0.021
regulation of cell cycle GO:0051726 281 0.021
lateral inhibition GO:0046331 1 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
negative regulation of interferon beta production GO:0032688 3 0.021
sensory perception of sound GO:0007605 97 0.021
face development GO:0060324 38 0.021
protein deacetylation GO:0006476 32 0.020
Human
regulation of actin filament based process GO:0032970 99 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.020
stress activated protein kinase signaling cascade GO:0031098 81 0.020
defense response to bacterium GO:0042742 119 0.020
somatic diversification of immunoglobulins GO:0016445 43 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
regulation of defense response to virus by host GO:0050691 8 0.020
Human
regulation of cell shape GO:0008360 39 0.020
development of primary female sexual characteristics GO:0046545 73 0.020
dna recombination GO:0006310 92 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
positive regulation of viral entry into host cell GO:0046598 3 0.020
response to alcohol GO:0097305 48 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
purine containing compound catabolic process GO:0072523 213 0.020
negative regulation of gene silencing GO:0060969 2 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
positive t cell selection GO:0043368 23 0.020
negative regulation of osteoblast proliferation GO:0033689 4 0.020
rna interference GO:0016246 2 0.019
positive regulation of protein catabolic process GO:0045732 60 0.019
synaptic transmission GO:0007268 329 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
spermatid development GO:0007286 108 0.019
organelle fission GO:0048285 170 0.019
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
regulation of cell adhesion GO:0030155 154 0.019
regulation of mitotic cell cycle phase transition GO:1901990 73 0.019

Pml disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.045
disease of cellular proliferation DOID:14566 0 0.045
immune system disease DOID:2914 0 0.025
disease of anatomical entity DOID:7 0 0.025
gastrointestinal system cancer DOID:3119 0 0.023
organ system cancer DOID:0050686 0 0.023