IMP

Process View

Mus musculus

10 genes annotated in mouse

cellular response to type i interferon

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to type i interferon"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to type i interferon" (in gray)

Name	Description	Probability	Func Analog Organism
Irf9	interferon regulatory factor 9	0.999	Mouse
Stat1	signal transducer and activator of transcription 1	0.985
Stat2	signal transducer and activator of transcription 2	0.950	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.854
Igtp	interferon gamma induced GTPase	0.777
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.770
Irgm1	immunity-related GTPase family M member 1	0.721
Usp18	ubiquitin specific peptidase 18	0.707
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.658
Irgm2	immunity-related GTPase family M member 2	0.642
Isg15	ISG15 ubiquitin-like modifier	0.558
Fas	Fas (TNF receptor superfamily member 6)	0.505
Trim21	tripartite motif-containing 21	0.478
Irf7	interferon regulatory factor 7	0.463
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.448
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.430
Stat3	signal transducer and activator of transcription 3	0.412	Mouse
Sfpi1	SFFV proviral integration 1	0.333
Ifi47	interferon gamma inducible protein 47	0.308
Uba7	ubiquitin-like modifier activating enzyme 7	0.287
Gbp2	guanylate binding protein 2	0.277
Unc93b1	unc-93 homolog B1 (C. elegans)	0.263
Tgtp2	T-cell specific GTPase 2	0.250
Ifi35	interferon-induced protein 35	0.245
Rtp4	receptor transporter protein 4	0.244
Socs3	suppressor of cytokine signaling 3	0.244
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.242
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.231
Gbp7	guanylate binding protein 7	0.197
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.191
Irf1	interferon regulatory factor 1	0.168	Mouse
Ifnar2	interferon (alpha and beta) receptor 2	0.160
Iigp1	interferon inducible GTPase 1	0.156
Parp14	poly (ADP-ribose) polymerase family, member 14	0.147
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.135
Tor3a	torsin family 3, member A	0.135
Gbp3	guanylate binding protein 3	0.125
Ifitm3	interferon induced transmembrane protein 3	0.110
Il6st	interleukin 6 signal transducer	0.108
Znfx1	zinc finger, NFX1-type containing 1	0.107
Ifih1	interferon induced with helicase C domain 1	0.104
Rsad2	radical S-adenosyl methionine domain containing 2	0.099
Foxp3	forkhead box P3	0.097
Myd88	myeloid differentiation primary response gene 88	0.091
Casp8	caspase 8	0.087
Lgals9	lectin, galactose binding, soluble 9	0.084
Bcl3	B-cell leukemia/lymphoma 3	0.080
Il4ra	interleukin 4 receptor, alpha	0.067
Ifitm2	interferon induced transmembrane protein 2	0.065
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.065	Human
Trim30a	tripartite motif-containing 30A	0.064
Ifnar1	interferon (alpha and beta) receptor 1	0.059
Jak2	Janus kinase 2	0.058
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.056
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.054
Pml	promyelocytic leukemia	0.054
Traf3	TNF receptor-associated factor 3	0.053
Ikbkg	inhibitor of kappaB kinase gamma	0.050
BC006779	cDNA sequence BC006779	0.050
Ikzf1	IKAROS family zinc finger 1	0.049
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.046
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.045
Birc3	baculoviral IAP repeat-containing 3	0.045
Il6	interleukin 6	0.045
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.044
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.043
Mx1	myxovirus (influenza virus) resistance 1	0.041
Pparg	peroxisome proliferator activated receptor gamma	0.041
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.038
Samhd1	SAM domain and HD domain, 1	0.038
Lepr	leptin receptor	0.036
Ncoa3	nuclear receptor coactivator 3	0.032
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.030
Trp63	transformation related protein 63	0.030
Jak1	Janus kinase 1	0.030
Icam1	intercellular adhesion molecule 1	0.029
Cd7	CD7 antigen	0.029
Cxcl10	chemokine (C-X-C motif) ligand 10	0.028
Parp10	poly (ADP-ribose) polymerase family, member 10	0.027
AW112010	expressed sequence AW112010	0.027
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.026
Kit	kit oncogene	0.026
Slfn2	schlafen 2	0.026
Fgfr2	fibroblast growth factor receptor 2	0.025
Parp12	poly (ADP-ribose) polymerase family, member 12	0.025
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.024
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.024
Arid1b	AT rich interactive domain 1B (SWI-like)	0.023
Ifi44	interferon-induced protein 44	0.022
Parp9	poly (ADP-ribose) polymerase family, member 9	0.022
Il1r1	interleukin 1 receptor, type I	0.021
Lyz2	lysozyme 2	0.020
Batf	basic leucine zipper transcription factor, ATF-like	0.020
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	0.020
Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial	0.020
Dock2	dedicator of cyto-kinesis 2	0.018
Ly6a	lymphocyte antigen 6 complex, locus A	0.018
Plac8	placenta-specific 8	0.017
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.017
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.017
Mx2	myxovirus (influenza virus) resistance 2	0.016
Daxx	Fas death domain-associated protein	0.016
Il18bp	interleukin 18 binding protein	0.016
Socs1	suppressor of cytokine signaling 1	0.016
Nmi	N-myc (and STAT) interactor	0.016
Sfn	stratifin	0.016
H2-Q7	histocompatibility 2, Q region locus 7	0.015
Nfil3	nuclear factor, interleukin 3, regulated	0.015
Trim25	tripartite motif-containing 25	0.015
Sp100	nuclear antigen Sp100	0.015
Oas1a	2'-5' oligoadenylate synthetase 1A	0.015
Ar	androgen receptor	0.015
Psmb10	proteasome (prosome, macropain) subunit, beta type 10	0.014
Plagl2	pleiomorphic adenoma gene-like 2	0.014
Flii	flightless I homolog (Drosophila)	0.014
Il17ra	interleukin 17 receptor A	0.014
Il27ra	interleukin 27 receptor, alpha	0.014
Trp53	transformation related protein 53	0.014
Tmem173	transmembrane protein 173	0.013
Ghr	growth hormone receptor	0.013
Prlr	prolactin receptor	0.013
Esr1	estrogen receptor 1 (alpha)	0.013
Igh	immunoglobulin heavy chain complex	0.013
Jak3	Janus kinase 3	0.013
Pgr	progesterone receptor	0.012
Tapbp	TAP binding protein	0.012
Irf4	interferon regulatory factor 4	0.012	Mouse
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.012
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.012
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.012
Ccl5	chemokine (C-C motif) ligand 5	0.012
Ifi27l2a	interferon, alpha-inducible protein 27 like 2A	0.012
D14Ertd668e	DNA segment, Chr 14, ERATO Doi 668, expressed	0.011
Atf1	activating transcription factor 1	0.011
Cxcl9	chemokine (C-X-C motif) ligand 9	0.011
Traf2	TNF receptor-associated factor 2	0.011
C920025E04Rik	RIKEN cDNA C920025E04 gene	0.011
Junb	Jun-B oncogene	0.011
Ly75	lymphocyte antigen 75	0.010
Herc6	hect domain and RLD 6	0.010
Tnip1	TNFAIP3 interacting protein 1	0.010
Stx11	syntaxin 11	0.010