|
|
negative regulation of jun kinase activity
|
GO:0043508 |
9 |
0.999
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle
|
GO:0031660 |
1 |
0.997
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.993
|
|
|
|
vitellogenesis
|
GO:0007296 |
2 |
0.992
|
|
|
|
regulation of protein deacetylation
|
GO:0090311 |
17 |
0.992
|
|
|
|
regulation of brown fat cell differentiation
|
GO:0090335 |
5 |
0.982
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.969
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.960
|
Mouse |
|
|
negative regulation of protein kinase activity by regulation of protein phosphorylation
|
GO:0044387 |
2 |
0.959
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.952
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.946
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.928
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.925
|
|
|
|
positive regulation of nuclear transcribed mrna poly a tail shortening
|
GO:0060213 |
4 |
0.923
|
|
|
|
protein deacetylation
|
GO:0006476 |
32 |
0.917
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.916
|
Fly |
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.913
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.912
|
Rat |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.912
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.896
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.880
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.874
|
Fly |
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.859
|
|
|
|
regulation of histone deacetylation
|
GO:0031063 |
12 |
0.858
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
20 |
0.858
|
|
|
|
circadian behavior
|
GO:0048512 |
13 |
0.857
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.852
|
Rat |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.850
|
|
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.846
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.840
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.832
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.824
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.819
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.819
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.816
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.815
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.812
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.811
|
|
|
|
locomotor rhythm
|
GO:0045475 |
8 |
0.790
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
3 |
0.790
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.785
|
Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.779
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
8 |
0.776
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.774
|
Rat |
|
|
neuron projection regeneration
|
GO:0031102 |
14 |
0.772
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.765
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.752
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.745
|
Fly |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.744
|
Rat |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.744
|
Rat |
|
|
labyrinthine layer blood vessel development
|
GO:0060716 |
21 |
0.737
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.736
|
|
|
|
axon regeneration
|
GO:0031103 |
12 |
0.736
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.731
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.721
|
Rat |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.719
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.719
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.715
|
Rat |
|
|
negative regulation of respiratory burst involved in inflammatory response
|
GO:0060266 |
1 |
0.713
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.706
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.687
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.680
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.662
|
|
|
|
protein deacylation
|
GO:0035601 |
36 |
0.655
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.655
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.650
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.645
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.632
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.626
|
Mouse |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.621
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.621
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
21 |
0.612
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.608
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.605
|
|
|
|
osteoblast proliferation
|
GO:0033687 |
18 |
0.601
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.601
|
Mouse |
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.597
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.595
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.591
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.585
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.584
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.566
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.564
|
Fly |
|
|
regulation of respiratory burst involved in inflammatory response
|
GO:0060264 |
2 |
0.562
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.561
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.560
|
Rat |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.556
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.553
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.553
|
Rat |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.553
|
Rat |
|
|
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:1900153 |
5 |
0.551
|
|
|
|
regulation of respiratory burst
|
GO:0060263 |
2 |
0.542
|
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
5 |
0.542
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.538
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.537
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.534
|
Human |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.526
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.523
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.523
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.522
|
Rat |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.520
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.516
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
34 |
0.514
|
Mouse |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.503
|
Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.499
|
Rat |
|
|
blastocyst development
|
GO:0001824 |
80 |
0.497
|
Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.497
|
Mouse |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.495
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.491
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.489
|
|
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.488
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.486
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.481
|
Human |
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.479
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.476
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.465
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
34 |
0.462
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.461
|
|
|
|
metanephric glomerular mesangium development
|
GO:0072223 |
3 |
0.456
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.452
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.449
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.448
|
|
|
|
conditioned taste aversion
|
GO:0001661 |
4 |
0.442
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.439
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
31 |
0.438
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.430
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.424
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.415
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.415
|
|
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.415
|
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
32 |
0.404
|
Rat |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.400
|
Human |
|
|
response to corticosterone
|
GO:0051412 |
1 |
0.396
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.393
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.392
|
|
|
|
positive regulation of transforming growth factor beta2 production
|
GO:0032915 |
2 |
0.391
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.388
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.387
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.378
|
|
|
|
regulation of transforming growth factor beta2 production
|
GO:0032909 |
2 |
0.377
|
Mouse |
|
|
positive regulation of protein deacetylation
|
GO:0090312 |
9 |
0.375
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.373
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.372
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.372
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.358
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.352
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.347
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.344
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.343
|
Zebrafish |
|
|
rhythmic behavior
|
GO:0007622 |
15 |
0.335
|
|
|
|
regulation of mrna 3 end processing
|
GO:0031440 |
6 |
0.332
|
|
|
|
renal filtration cell differentiation
|
GO:0061318 |
10 |
0.328
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
9 |
0.328
|
Human |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.325
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.323
|
Rat |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.321
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.320
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.319
|
|
|
|
cellular response to calcium ion
|
GO:0071277 |
14 |
0.300
|
|
|
|
positive regulation of histone deacetylation
|
GO:0031065 |
7 |
0.297
|
|
|
|
glomerular epithelial cell differentiation
|
GO:0072311 |
10 |
0.290
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.290
|
|
|
|
negative regulation of respiratory burst
|
GO:0060268 |
1 |
0.290
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.280
|
|
|
|
regulation of ovulation
|
GO:0060278 |
3 |
0.279
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.277
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.276
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.275
|
Rat |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.270
|
|
|
|
rhombomere morphogenesis
|
GO:0021593 |
2 |
0.267
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.267
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.265
|
|
|
|
metanephric glomerular mesangial cell proliferation involved in metanephros development
|
GO:0072262 |
3 |
0.264
|
|
|
|
nuclear transcribed mrna poly a tail shortening
|
GO:0000289 |
7 |
0.264
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.262
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.256
|
|
|
|
brain segmentation
|
GO:0035284 |
3 |
0.254
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.253
|
|
|
|
respiratory burst
|
GO:0045730 |
8 |
0.253
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
11 |
0.246
|
Fly |
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.246
|
Mouse |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.244
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.242
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.235
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.231
|
|
|
|
positive regulation of brown fat cell differentiation
|
GO:0090336 |
4 |
0.230
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.230
|
Fly |
|
|
negative regulation of ovulation
|
GO:0060280 |
1 |
0.228
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.228
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.227
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.227
|
|
|
|
type i pneumocyte differentiation
|
GO:0060509 |
7 |
0.222
|
|
|
|
central nervous system segmentation
|
GO:0035283 |
3 |
0.218
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.218
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.216
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.216
|
|
|
|
post embryonic camera type eye development
|
GO:0031077 |
8 |
0.215
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
20 |
0.214
|
|
|
|
regulation of microvillus assembly
|
GO:0032534 |
3 |
0.212
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.212
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.209
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.207
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.207
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.204
|
Rat |
|
|
general adaptation syndrome
|
GO:0051866 |
2 |
0.201
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.195
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.190
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.190
|
Rat |
|
|
skin development
|
GO:0043588 |
220 |
0.187
|
|
|
|
ossification involved in bone maturation
|
GO:0043931 |
12 |
0.186
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.186
|
|
|
|
respiratory burst involved in inflammatory response
|
GO:0002536 |
3 |
0.183
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.181
|
Fly |
|
|
neural tube development
|
GO:0021915 |
160 |
0.180
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.178
|
|
|
|
cardiac muscle hypertrophy in response to stress
|
GO:0014898 |
10 |
0.176
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.175
|
|
|
|
wound healing spreading of cells
|
GO:0044319 |
8 |
0.175
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
23 |
0.175
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.171
|
|
|
|
adrenal cortex formation
|
GO:0035802 |
2 |
0.170
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.169
|
|
|
|
glomerular visceral epithelial cell differentiation
|
GO:0072112 |
10 |
0.167
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.165
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.163
|
Human |
|
|
associative learning
|
GO:0008306 |
61 |
0.163
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.162
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.162
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.158
|
|
|
|
optic nerve morphogenesis
|
GO:0021631 |
6 |
0.156
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.155
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.155
|
Human |
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
14 |
0.154
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.153
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.152
|
Zebrafish |
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.152
|
|
|
|
rhombomere formation
|
GO:0021594 |
1 |
0.151
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.151
|
|
|
|
rhombomere 5 development
|
GO:0021571 |
4 |
0.151
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.149
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.148
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.148
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.146
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.144
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.142
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.141
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.140
|
Mouse |
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
1 |
0.139
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.138
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.136
|
Rat |
|
|
positive regulation of rhodopsin gene expression
|
GO:0045872 |
2 |
0.133
|
|
|
|
cellular response to antibiotic
|
GO:0071236 |
4 |
0.130
|
|
|
|
response to mineralocorticoid
|
GO:0051385 |
1 |
0.129
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.128
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.128
|
Rat |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.126
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.126
|
Rat |
|
|
response to organophosphorus
|
GO:0046683 |
22 |
0.124
|
Rat |
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.122
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.121
|
Mouse |
|
|
liver development
|
GO:0001889 |
66 |
0.120
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.119
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061418 |
2 |
0.119
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.118
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.117
|
|
|
|
thorax and anterior abdomen determination
|
GO:0007356 |
1 |
0.116
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.116
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.114
|
|
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
33 |
0.114
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.114
|
Rat |
|
|
gastrulation
|
GO:0007369 |
116 |
0.113
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.112
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.111
|
|
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.110
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.109
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.109
|
Rat |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
23 |
0.109
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.108
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
1 |
0.108
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.108
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.106
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.104
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.103
|
|
|
|
adrenal cortex development
|
GO:0035801 |
2 |
0.102
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.102
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.102
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.102
|
|
|
|
rhombomere 3 formation
|
GO:0021660 |
1 |
0.101
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.101
|
Fly |
|
|
heart valve morphogenesis
|
GO:0003179 |
21 |
0.101
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.100
|
|
|
|
kidney vasculature development
|
GO:0061440 |
15 |
0.100
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.100
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.100
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
7 |
0.100
|
|
|
|
chorio allantoic fusion
|
GO:0060710 |
8 |
0.099
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.099
|
|
|
|
regulation of metanephros development
|
GO:0072215 |
15 |
0.099
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.098
|
Fly |
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.098
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.097
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.097
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
20 |
0.097
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.097
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.096
|
|
|
|
regulation of mrna catabolic process
|
GO:0061013 |
6 |
0.096
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.096
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.096
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.095
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.095
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.094
|
|
|
|
nerve development
|
GO:0021675 |
67 |
0.093
|
|
|
|
regulation of nuclear transcribed mrna poly a tail shortening
|
GO:0060211 |
4 |
0.092
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.091
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.090
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.089
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.089
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.089
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.089
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.089
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.089
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.089
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.088
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.088
|
Worm |
|
|
kidney development
|
GO:0001822 |
213 |
0.088
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.087
|
|
|
|
labyrinthine layer morphogenesis
|
GO:0060713 |
21 |
0.087
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.087
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.087
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.086
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.086
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.085
|
|
|
|
rhombomere 5 formation
|
GO:0021666 |
1 |
0.085
|
|
|
|
epiboly
|
GO:0090504 |
8 |
0.085
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.084
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.084
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
4 |
0.083
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.083
|
|
|
|
cell differentiation involved in kidney development
|
GO:0061005 |
33 |
0.082
|
|
|
|
intestinal epithelial cell development
|
GO:0060576 |
12 |
0.080
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.080
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.079
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.079
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.079
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.079
|
|
|
|
autonomic nervous system development
|
GO:0048483 |
43 |
0.078
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.077
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.077
|
Human |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.077
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.077
|
Human |
|
|
response to immobilization stress
|
GO:0035902 |
1 |
0.076
|
|
|
|
heart growth
|
GO:0060419 |
45 |
0.076
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.076
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.076
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.076
|
Fly |
|
|
lung epithelial cell differentiation
|
GO:0060487 |
29 |
0.075
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.075
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.075
|
|
|
|
forebrain radial glial cell differentiation
|
GO:0021861 |
4 |
0.074
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.074
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.073
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.073
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.072
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.072
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.072
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.072
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.072
|
Human |
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.072
|
|
|
|
metanephric s shaped body morphogenesis
|
GO:0072284 |
2 |
0.071
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.071
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.071
|
|
|
|
cytoplasm organization
|
GO:0007028 |
8 |
0.071
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.071
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.071
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.070
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.070
|
|
|
|
regulation of microvillus organization
|
GO:0032530 |
3 |
0.070
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.070
|
|
|
|
ectodermal digestive tract development
|
GO:0007439 |
1 |
0.069
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.068
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.068
|
Fly |
|
|
nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:0000288 |
12 |
0.067
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.067
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.067
|
|
|
|
intussusceptive angiogenesis
|
GO:0002041 |
2 |
0.067
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.066
|
Fly |
|
|
gland development
|
GO:0048732 |
330 |
0.066
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.066
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.066
|
Human |
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.065
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.065
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.064
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.064
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.063
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
26 |
0.063
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.063
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
17 |
0.063
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.063
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.063
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.063
|
Rat |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.062
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.062
|
Human |
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.062
|
|
|
|
cranial nerve development
|
GO:0021545 |
41 |
0.061
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.061
|
Human |
|
|
cellular response to heparin
|
GO:0071504 |
1 |
0.061
|
|
|
|
osmosensory signaling pathway
|
GO:0007231 |
1 |
0.061
|
|
|
|
cranial nerve formation
|
GO:0021603 |
4 |
0.061
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.061
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.060
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.060
|
|
|
|
positive regulation of mrna catabolic process
|
GO:0061014 |
5 |
0.060
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.060
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.059
|
|
|
|
p38mapk cascade
|
GO:0038066 |
4 |
0.059
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.059
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
41 |
0.059
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.059
|
|
|
|
mrna catabolic process
|
GO:0006402 |
22 |
0.059
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.058
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
6 |
0.058
|
Fly |
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.056
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.056
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.056
|
|
|
|
regulation of kidney development
|
GO:0090183 |
40 |
0.056
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.055
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.055
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.055
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.055
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.055
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.054
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.054
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.054
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
24 |
0.053
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.053
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.053
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.053
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
11 |
0.053
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.053
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
5 |
0.052
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.051
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.051
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.050
|
|
|
|
embryonic placenta morphogenesis
|
GO:0060669 |
25 |
0.050
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.050
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.050
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.049
|
|
|
|
epithalamus development
|
GO:0021538 |
2 |
0.049
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.049
|
|
|
|
spongiotrophoblast layer development
|
GO:0060712 |
15 |
0.049
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
51 |
0.049
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.049
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
3 |
0.049
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.049
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.048
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.048
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.048
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.048
|
Human |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.048
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.047
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.047
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.047
|
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.047
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
31 |
0.047
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.047
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.047
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.047
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.047
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.047
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.047
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.046
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.046
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.046
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.046
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.046
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.045
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.045
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.045
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.045
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.044
|
|
|
|
negative regulation of metanephric glomerular mesangial cell proliferation
|
GO:0072302 |
1 |
0.044
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.044
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.044
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.044
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.044
|
Human |
|
|
glucose transport
|
GO:0015758 |
56 |
0.044
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.044
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.044
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.043
|
|
|
|
regulation of rhodopsin gene expression
|
GO:0007468 |
3 |
0.043
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.043
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.043
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.043
|
|
