IMP

Process View

Mus musculus

8 genes annotated in mouse

regulation of transcription from rna polymerase ii promoter in response to stress

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transcription from rna polymerase ii promoter in response to stress"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of transcription from rna polymerase ii promoter in response to stress" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	1.000
Mapk14	mitogen-activated protein kinase 14	1.000	Yeast
Fos	FBJ osteosarcoma oncogene	0.998
Ctnnb1	catenin (cadherin associated protein), beta 1	0.994
Hif1a	hypoxia inducible factor 1, alpha subunit	0.982
Vhl	von Hippel-Lindau tumor suppressor	0.975	Human
Vegfa	vascular endothelial growth factor A	0.971	Human
Dusp1	dual specificity phosphatase 1	0.965
Rxra	retinoid X receptor alpha	0.960
Mapk8	mitogen-activated protein kinase 8	0.912	Yeast
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.879
Trp53	transformation related protein 53	0.873	Fly
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.855
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.837
Notch2	Notch gene homolog 2 (Drosophila)	0.830	Mouse
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.829
Jun	Jun oncogene	0.776	Human
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.744
Psen1	presenilin 1	0.707
Klf4	Kruppel-like factor 4 (gut)	0.610
Fgfr2	fibroblast growth factor receptor 2	0.610
Btg2	B-cell translocation gene 2, anti-proliferative	0.574
Ahr	aryl-hydrocarbon receptor	0.566
Klf6	Kruppel-like factor 6	0.564
Arid1a	AT rich interactive domain 1A (SWI-like)	0.525
Egln1	EGL nine homolog 1 (C. elegans)	0.523
Nos3	nitric oxide synthase 3, endothelial cell	0.489
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.477
Jag1	jagged 1	0.462
Fgf8	fibroblast growth factor 8	0.462
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.458
Trib3	tribbles homolog 3 (Drosophila)	0.455
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.443
Ier2	immediate early response 2	0.424
Atf3	activating transcription factor 3	0.424
Trp63	transformation related protein 63	0.383	Fly
Adam17	a disintegrin and metallopeptidase domain 17	0.370
Rhob	ras homolog gene family, member B	0.352
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.349
Gata4	GATA binding protein 4	0.318
Arid1b	AT rich interactive domain 1B (SWI-like)	0.274
Shh	sonic hedgehog	0.233
Hdac1	histone deacetylase 1	0.229
Rb1	retinoblastoma 1	0.223
Mef2d	myocyte enhancer factor 2D	0.217	Yeast
Bcl2	B-cell leukemia/lymphoma 2	0.214
Hdac4	histone deacetylase 4	0.211
Mapk11	mitogen-activated protein kinase 11	0.199	Yeast
Hbb-b1	hemoglobin, beta adult major chain	0.195
Hdac5	histone deacetylase 5	0.195
Pitx2	paired-like homeodomain transcription factor 2	0.191
Foxo1	forkhead box O1	0.190
Suds3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.176
Sox2	SRY-box containing gene 2	0.175
Emx1	empty spiracles homolog 1 (Drosophila)	0.175
Egfr	epidermal growth factor receptor	0.171
Notch1	Notch gene homolog 1 (Drosophila)	0.160
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.156
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.147
Rnf220	ring finger protein 220	0.145
Gdnf	glial cell line derived neurotrophic factor	0.144
Junb	Jun-B oncogene	0.142
Smad1	MAD homolog 1 (Drosophila)	0.140
Epas1	endothelial PAS domain protein 1	0.138
Apoe	apolipoprotein E	0.135
Chd7	chromodomain helicase DNA binding protein 7	0.134
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.133
Hdac7	histone deacetylase 7	0.131
Dll1	delta-like 1 (Drosophila)	0.131
Emx2	empty spiracles homolog 2 (Drosophila)	0.128
Grb10	growth factor receptor bound protein 10	0.122
Zfp36	zinc finger protein 36	0.119
Ptgs2	prostaglandin-endoperoxide synthase 2	0.111
Foxc1	forkhead box C1	0.109
Egr1	early growth response 1	0.108
Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	0.107
Mapkapk2	MAP kinase-activated protein kinase 2	0.104
Skil	SKI-like	0.097
Lepr	leptin receptor	0.093
Stat3	signal transducer and activator of transcription 3	0.088
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.087	Yeast
Atf2	activating transcription factor 2	0.086
Hr	hairless	0.086
Lama5	laminin, alpha 5	0.085
Ntf3	neurotrophin 3	0.084
Sfn	stratifin	0.082
Gata3	GATA binding protein 3	0.082
Otp	orthopedia homolog (Drosophila)	0.081
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.080
Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.078	Yeast
Efnb2	ephrin B2	0.077
Mknk2	MAP kinase-interacting serine/threonine kinase 2	0.076
Rara	retinoic acid receptor, alpha	0.074
Pou5f1	POU domain, class 5, transcription factor 1	0.074
Mecp2	methyl CpG binding protein 2	0.073
Nab2	Ngfi-A binding protein 2	0.072
Egr2	early growth response 2	0.071	Mouse
Sertad1	SERTA domain containing 1	0.069
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.065
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.064
Egfl7	EGF-like domain 7	0.064
Pkd1	polycystic kidney disease 1 homolog	0.064
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.062
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.060
Tbx1	T-box 1	0.060
Sox9	SRY-box containing gene 9	0.058
Lhx1	LIM homeobox protein 1	0.057
Apc	adenomatosis polyposis coli	0.055
Errfi1	ERBB receptor feedback inhibitor 1	0.054
Sp1	trans-acting transcription factor 1	0.053
Fosb	FBJ osteosarcoma oncogene B	0.049
Klf3	Kruppel-like factor 3 (basic)	0.049
Rac1	RAS-related C3 botulinum substrate 1	0.049
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.046
Rdh10	retinol dehydrogenase 10 (all-trans)	0.045
Sqstm1	sequestosome 1	0.045
Ep300	E1A binding protein p300	0.044
Atf4	activating transcription factor 4	0.043
Psen2	presenilin 2	0.042
Smad5	MAD homolog 5 (Drosophila)	0.042
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.041
Crebbp	CREB binding protein	0.040
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.039
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.039
Mef2c	myocyte enhancer factor 2C	0.038	Yeast
Mdm2	transformed mouse 3T3 cell double minute 2	0.036
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.033	Human
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.033
Tcf4	transcription factor 4	0.033
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.032
Klc1	kinesin light chain 1	0.031
Prkce	protein kinase C, epsilon	0.031
Mcl1	myeloid cell leukemia sequence 1	0.031
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.030
Snrk	SNF related kinase	0.030
Ncoa3	nuclear receptor coactivator 3	0.028
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.028
Col4a3	collagen, type IV, alpha 3	0.027
Rarb	retinoic acid receptor, beta	0.026
Tcfap2a	transcription factor AP-2, alpha	0.026
Pax2	paired box gene 2	0.026
Rbl2	retinoblastoma-like 2	0.026
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.025
Smad3	MAD homolog 3 (Drosophila)	0.025
Ubc	ubiquitin C	0.025
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.025
Pax3	paired box gene 3	0.025
Isl1	ISL1 transcription factor, LIM/homeodomain	0.024
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.024
Kit	kit oncogene	0.023
Zfp362	zinc finger protein 362	0.023
Mapk9	mitogen-activated protein kinase 9	0.022	Yeast
Nab1	Ngfi-A binding protein 1	0.022
Mtmr1	myotubularin related protein 1	0.022
Vangl2	vang-like 2 (van gogh, Drosophila)	0.022
Sox18	SRY-box containing gene 18	0.022
Hoxa1	homeobox A1	0.022
Hipk3	homeodomain interacting protein kinase 3	0.022
Yap1	yes-associated protein 1	0.022
Bhlhe40	basic helix-loop-helix family, member e40	0.021
Myc	myelocytomatosis oncogene	0.021
Braf	Braf transforming gene	0.021
Klf7	Kruppel-like factor 7 (ubiquitous)	0.021
Lims1	LIM and senescent cell antigen-like domains 1	0.020
Wt1	Wilms tumor 1 homolog	0.020	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.020
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.019
Trp73	transformation related protein 73	0.019	Fly
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.019
Cyr61	cysteine rich protein 61	0.019
Dlg1	discs, large homolog 1 (Drosophila)	0.018
Mef2a	myocyte enhancer factor 2A	0.018	Yeast
Lef1	lymphoid enhancer binding factor 1	0.018
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.017
Sall4	sal-like 4 (Drosophila)	0.017
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.017
Bmp4	bone morphogenetic protein 4	0.017
Gata6	GATA binding protein 6	0.017
Rarg	retinoic acid receptor, gamma	0.017
Qk	quaking	0.016
Klf2	Kruppel-like factor 2 (lung)	0.016	Human
Otx2	orthodenticle homolog 2 (Drosophila)	0.016
Rbl1	retinoblastoma-like 1 (p107)	0.016
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.016
Arnt	aryl hydrocarbon receptor nuclear translocator	0.016	Human
Dusp2	dual specificity phosphatase 2	0.015
Csnk1e	casein kinase 1, epsilon	0.015
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.014
Epor	erythropoietin receptor	0.014
Sox17	SRY-box containing gene 17	0.014
Brca1	breast cancer 1	0.014
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.014
Rasip1	Ras interacting protein 1	0.014
Smad7	MAD homolog 7 (Drosophila)	0.014
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.014
Egln3	EGL nine homolog 3 (C. elegans)	0.013
Mknk1	MAP kinase-interacting serine/threonine kinase 1	0.013
Hspa1a	heat shock protein 1A	0.013
Itga3	integrin alpha 3	0.013
Per1	period homolog 1 (Drosophila)	0.013
Sim2	single-minded homolog 2 (Drosophila)	0.013	Mouse
Ifrd1	interferon-related developmental regulator 1	0.013
Tmprss6	transmembrane serine protease 6	0.013
Wasf1	WASP family 1	0.012
Pparg	peroxisome proliferator activated receptor gamma	0.012
Dll4	delta-like 4 (Drosophila)	0.012
Ar	androgen receptor	0.012
Smarcc2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.012
Asxl1	additional sex combs like 1 (Drosophila)	0.012
Raf1	v-raf-leukemia viral oncogene 1	0.012
Sall3	sal-like 3 (Drosophila)	0.012
Zeb2	zinc finger E-box binding homeobox 2	0.012
Gadd45b	growth arrest and DNA-damage-inducible 45 beta	0.011
Sox4	SRY-box containing gene 4	0.011
Zmynd11	zinc finger, MYND domain containing 11	0.011
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.011
Fzd4	frizzled homolog 4 (Drosophila)	0.011
Smad4	MAD homolog 4 (Drosophila)	0.011
Hip1	huntingtin interacting protein 1	0.011
Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	0.011
Ulk2	Unc-51 like kinase 2 (C. elegans)	0.011
E2f1	E2F transcription factor 1	0.010
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.010
Amh	anti-Mullerian hormone	0.010
Rab12	RAB12, member RAS oncogene family	0.010
Irx1	Iroquois related homeobox 1 (Drosophila)	0.010
Pitx1	paired-like homeodomain transcription factor 1	0.010
Igfbp3	insulin-like growth factor binding protein 3	0.010