Mus musculus

0 known processes

Trim33

tripartite motif-containing 33

(Aliases: mKIAA1113,Tif1g,AI413936,ectodermin,8030451N04Rik,Ecto,DKFZp586K1123)

Trim33 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.364
chromatin organization GO:0006325 206 0.249
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.213
regulation of cellular amino acid metabolic process GO:0006521 5 0.204
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.167
stem cell development GO:0048864 219 0.128
Mouse
immune effector process GO:0002252 321 0.123
peptidyl amino acid modification GO:0018193 336 0.122
dna metabolic process GO:0006259 303 0.115
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.113
regulation of histone modification GO:0031056 56 0.110
macromolecule methylation GO:0043414 120 0.109
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.102
actin filament organization GO:0007015 113 0.095
leukocyte differentiation GO:0002521 342 0.089
rna processing GO:0006396 105 0.088
lung development GO:0030324 164 0.085
regulation of protein stability GO:0031647 52 0.084
Mouse
cell type specific apoptotic process GO:0097285 268 0.082
cellular amine metabolic process GO:0044106 44 0.079
cellular amino acid metabolic process GO:0006520 103 0.077
regulation of chromatin modification GO:1903308 57 0.074
posttranscriptional regulation of gene expression GO:0010608 155 0.073
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.073
stem cell differentiation GO:0048863 268 0.072
Mouse
protein catabolic process GO:0030163 221 0.069
Mouse
homeostasis of number of cells GO:0048872 210 0.068
Zebrafish
methylation GO:0032259 134 0.067
Mouse
regulation of cellular component size GO:0032535 121 0.064
respiratory tube development GO:0030323 167 0.059
histone modification GO:0016570 159 0.058
lymphocyte differentiation GO:0030098 242 0.058
gastrulation GO:0007369 116 0.058
cellular response to dna damage stimulus GO:0006974 207 0.057
cellular ketone metabolic process GO:0042180 84 0.057
gland development GO:0048732 330 0.056
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.056
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.056
regulation of histone methylation GO:0031060 30 0.055
positive regulation of apoptotic process GO:0043065 217 0.055
blood vessel morphogenesis GO:0048514 285 0.055
t cell activation GO:0042110 289 0.054
positive regulation of transcription by galactose GO:0000411 1 0.054
cellular protein catabolic process GO:0044257 155 0.054
histone lysine methylation GO:0034968 50 0.053
organic cyclic compound catabolic process GO:1901361 295 0.052
regulation of chromosome organization GO:0033044 83 0.050
ubiquitin dependent protein catabolic process GO:0006511 129 0.049
negative regulation of immune system process GO:0002683 209 0.049
regulation of histone h3 k9 methylation GO:0051570 8 0.049
respiratory system development GO:0060541 190 0.049
modification dependent protein catabolic process GO:0019941 133 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.047
histone h3 k9 methylation GO:0051567 17 0.047
spermatid differentiation GO:0048515 115 0.046
defense response to other organism GO:0098542 197 0.045
chromatin modification GO:0016568 187 0.044
mitotic cell cycle GO:0000278 195 0.044
peptidyl lysine methylation GO:0018022 29 0.043
small gtpase mediated signal transduction GO:0007264 97 0.043
modification dependent macromolecule catabolic process GO:0043632 133 0.043
amine metabolic process GO:0009308 45 0.042
heterocycle catabolic process GO:0046700 280 0.041
t cell differentiation GO:0030217 174 0.041
macromolecule catabolic process GO:0009057 281 0.040
Mouse
aromatic compound catabolic process GO:0019439 286 0.039
positive regulation of protein modification process GO:0031401 299 0.039
regulation of organelle organization GO:0033043 289 0.038
regulation of apoptotic signaling pathway GO:2001233 197 0.038
rap protein signal transduction GO:0032486 3 0.038
digestive system development GO:0055123 200 0.038
positive regulation of nervous system development GO:0051962 221 0.037
regulation of cell motility GO:2000145 236 0.037
regionalization GO:0003002 337 0.037
dna methylation GO:0006306 43 0.036
Mouse
regulation of rap protein signal transduction GO:0032487 6 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
stem cell proliferation GO:0072089 117 0.036
learning GO:0007612 98 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
regulation of cell adhesion GO:0030155 154 0.035
regulation of hydrolase activity GO:0051336 246 0.035
positive regulation of cell motility GO:2000147 116 0.035
negative regulation of cellular component organization GO:0051129 194 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
nucleoside metabolic process GO:0009116 246 0.035
histone h3 k9 dimethylation GO:0036123 4 0.034
positive regulation of cellular component biogenesis GO:0044089 94 0.034
stem cell maintenance GO:0019827 130 0.034
innate immune response GO:0045087 157 0.034
response to growth factor GO:0070848 198 0.033
Human
compound eye development GO:0048749 1 0.033
protein ubiquitination GO:0016567 171 0.033
Human Mouse
inflammatory response GO:0006954 244 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
Human
cd4 positive alpha beta t cell activation GO:0035710 45 0.032
nucleobase containing small molecule metabolic process GO:0055086 352 0.031
oocyte axis specification GO:0007309 2 0.030
negative regulation of cell cycle GO:0045786 123 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.030
Human
positive regulation of protein phosphorylation GO:0001934 242 0.030
cellular response to lipid GO:0071396 145 0.030
Mouse
regulation of ras gtpase activity GO:0032318 88 0.030
rho protein signal transduction GO:0007266 32 0.030
negative regulation of mitotic cell cycle GO:0045930 58 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
male gamete generation GO:0048232 285 0.029
response to organonitrogen compound GO:0010243 246 0.029
endoderm development GO:0007492 45 0.029
positive regulation of organelle organization GO:0010638 128 0.029
peptidyl lysine modification GO:0018205 77 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.029
regulation of cell cycle GO:0051726 281 0.028
skeletal system morphogenesis GO:0048705 203 0.028
histone methylation GO:0016571 71 0.028
regulation of vesicle mediated transport GO:0060627 139 0.028
ras protein signal transduction GO:0007265 77 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.027
Human
carbon catabolite regulation of transcription GO:0045990 4 0.027
protein methylation GO:0006479 81 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
sensory organ morphogenesis GO:0090596 242 0.027
microtubule based process GO:0007017 236 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.026
Human Mouse
protein modification by small protein conjugation GO:0032446 187 0.026
Human Mouse
carbon catabolite activation of transcription GO:0045991 4 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
organelle fission GO:0048285 170 0.026
regulation of cell projection organization GO:0031344 206 0.026
wound healing GO:0042060 157 0.026
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.025
Human
germ cell development GO:0007281 185 0.025
ameboidal type cell migration GO:0001667 128 0.025
regulation of chromatin organization GO:1902275 57 0.025
positive regulation of ras gtpase activity GO:0032320 65 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
cell growth GO:0016049 130 0.025
regulation of t cell activation GO:0050863 170 0.025
positive regulation of cell development GO:0010720 237 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
Human
regulation of cell activation GO:0050865 289 0.025
cytoplasmic transport GO:0016482 234 0.025
developmental maturation GO:0021700 193 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.025
protein targeting GO:0006605 143 0.025
regulation of anatomical structure size GO:0090066 178 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
negative regulation of organelle organization GO:0010639 90 0.024
jak stat cascade GO:0007259 42 0.024
male gonad development GO:0008584 88 0.024
regulation of transcription by galactose GO:0000409 1 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
negative regulation of neuron death GO:1901215 98 0.024
regulation of nucleoside metabolic process GO:0009118 130 0.024
organelle assembly GO:0070925 177 0.024
spinal cord development GO:0021510 81 0.024
carbohydrate metabolic process GO:0005975 230 0.023
nucleotide metabolic process GO:0009117 332 0.023
purine nucleotide catabolic process GO:0006195 211 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
dna recombination GO:0006310 92 0.023
endocytosis GO:0006897 168 0.023
snrna metabolic process GO:0016073 1 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of neuron death GO:1901214 134 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.023
regulation of chromatin silencing GO:0031935 2 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
negative regulation of t cell activation GO:0050868 65 0.022
regulation of neuron projection development GO:0010975 169 0.022
spermatogenesis GO:0007283 284 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.022
protein maturation GO:0051604 176 0.022
myeloid cell differentiation GO:0030099 233 0.022
Zebrafish
negative regulation of histone modification GO:0031057 18 0.022
mitotic cell cycle process GO:1903047 159 0.021
muscle tissue development GO:0060537 308 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
somatic stem cell maintenance GO:0035019 47 0.021
digestive tract morphogenesis GO:0048546 147 0.021
multicellular organism growth GO:0035264 161 0.021
snrna processing GO:0016180 1 0.021
camera type eye development GO:0043010 266 0.021
positive regulation of cell migration GO:0030335 109 0.021
development of primary male sexual characteristics GO:0046546 88 0.020
negative regulation of leukocyte differentiation GO:1902106 51 0.020
neural tube formation GO:0001841 108 0.020
protein acylation GO:0043543 64 0.020
neuron apoptotic process GO:0051402 142 0.020
guanosine containing compound catabolic process GO:1901069 144 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
cell substrate adhesion GO:0031589 130 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
muscle cell differentiation GO:0042692 261 0.020
positive regulation of neuron differentiation GO:0045666 141 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
mitotic nuclear division GO:0007067 48 0.019
male sex differentiation GO:0046661 109 0.019
neuron death GO:0070997 154 0.019
regulation of innate immune response GO:0045088 91 0.019
negative regulation of nervous system development GO:0051961 156 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
digestive tract development GO:0048565 190 0.019
negative regulation of chromatin modification GO:1903309 19 0.019
regulation of t cell differentiation GO:0045580 83 0.018
negative regulation of apoptotic signaling pathway GO:2001234 104 0.018
response to radiation GO:0009314 165 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
mapk cascade GO:0000165 281 0.018
positive regulation of innate immune response GO:0045089 80 0.018
response to insulin GO:0032868 100 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
regulation of protein complex assembly GO:0043254 83 0.018
organonitrogen compound catabolic process GO:1901565 264 0.017
negative regulation of cell development GO:0010721 169 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
cell maturation GO:0048469 127 0.017
exocytosis GO:0006887 121 0.017
regulation of protein catabolic process GO:0042176 108 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
heart morphogenesis GO:0003007 178 0.017
photoreceptor cell development GO:0042461 40 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
nucleoside catabolic process GO:0009164 206 0.017
positive regulation of rac protein signal transduction GO:0035022 1 0.017
protein autophosphorylation GO:0046777 61 0.017
Mouse
regulation of autophagy GO:0010506 30 0.017
photoreceptor cell morphogenesis GO:0008594 3 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
skin development GO:0043588 220 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
negative regulation of histone h3 k9 methylation GO:0051573 4 0.017
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.017
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
regulation of cytokine production GO:0001817 266 0.016
positive regulation of chromosome organization GO:2001252 33 0.016
negative regulation of cellular catabolic process GO:0031330 47 0.016
spermatid development GO:0007286 108 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of rap gtpase activity GO:0032854 3 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
Mouse
response to light stimulus GO:0009416 135 0.016
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
negative regulation of immune effector process GO:0002698 55 0.015
adaptive immune response GO:0002250 155 0.015
positive regulation of kinase activity GO:0033674 155 0.015
cytokine production GO:0001816 319 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
endoderm formation GO:0001706 20 0.015
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.015
regulation of cell cycle phase transition GO:1901987 77 0.015
protein processing GO:0016485 163 0.015
alpha beta t cell activation GO:0046631 91 0.015
bmp signaling pathway GO:0030509 93 0.015
Human
cell adhesion GO:0007155 329 0.015
mitotic cell cycle checkpoint GO:0007093 31 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
regulation of hormone levels GO:0010817 211 0.014
internal protein amino acid acetylation GO:0006475 42 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
peripheral nervous system development GO:0007422 53 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
cellular response to organic cyclic compound GO:0071407 87 0.014
Mouse
gene silencing GO:0016458 38 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of mapk cascade GO:0043408 248 0.014
regulation of transferase activity GO:0051338 263 0.014
limb development GO:0060173 166 0.013
axonogenesis GO:0007409 274 0.013
Fly
glycosyl compound metabolic process GO:1901657 246 0.013
regulation of defense response GO:0031347 233 0.013
apoptotic signaling pathway GO:0097190 306 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
regulation of actin filament based process GO:0032970 99 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.013
formation of primary germ layer GO:0001704 77 0.013
mesodermal cell migration GO:0008078 4 0.013
cellular protein complex assembly GO:0043623 116 0.013
b cell differentiation GO:0030183 78 0.013
cell activation involved in immune response GO:0002263 126 0.013
cellular response to external stimulus GO:0071496 88 0.013
Mouse
actin filament polymerization GO:0030041 44 0.013
positive regulation of cytoskeleton organization GO:0051495 49 0.013
cognition GO:0050890 149 0.013
purine containing compound metabolic process GO:0072521 311 0.013
ossification GO:0001503 216 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013
anatomical structure homeostasis GO:0060249 145 0.013
blastocyst development GO:0001824 80 0.013
oocyte construction GO:0007308 2 0.013
dna repair GO:0006281 107 0.013
skeletal muscle organ development GO:0060538 163 0.013
response to transforming growth factor beta GO:0071559 88 0.013
Human
regulation of exocytosis GO:0017157 61 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
mrna metabolic process GO:0016071 84 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
embryonic hemopoiesis GO:0035162 23 0.012
Zebrafish
regulation of cell migration GO:0030334 219 0.012
development of primary sexual characteristics GO:0045137 143 0.012
regulation of secretion GO:0051046 274 0.012
lung morphogenesis GO:0060425 50 0.012
b cell activation GO:0042113 161 0.012
regulation of jak stat cascade GO:0046425 34 0.012
regulation of dna methylation GO:0044030 12 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
regulation of alpha beta t cell differentiation GO:0046637 35 0.012
chemotaxis GO:0006935 247 0.012
Fly
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of proteolysis GO:0030162 164 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
negative regulation of growth GO:0045926 99 0.012
protein localization to nucleus GO:0034504 121 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
Human
regulation of cellular protein catabolic process GO:1903362 61 0.012
protein localization to organelle GO:0033365 185 0.012
negative regulation of protein modification process GO:0031400 163 0.012
regulation of cell size GO:0008361 72 0.012
epithelial cell development GO:0002064 159 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
hepaticobiliary system development GO:0061008 67 0.012
regulation of ossification GO:0030278 112 0.012
nuclear import GO:0051170 95 0.012
rna 3 end processing GO:0031123 20 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
cellular homeostasis GO:0019725 240 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
mitotic sister chromatid cohesion GO:0007064 1 0.012
negative regulation of histone methylation GO:0031061 10 0.011
somitogenesis GO:0001756 69 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
cellular response to starvation GO:0009267 57 0.011
neural tube development GO:0021915 160 0.011
negative regulation of defense response GO:0031348 77 0.011
ear morphogenesis GO:0042471 118 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.011
actin cytoskeleton organization GO:0030036 220 0.011
protein import into nucleus GO:0006606 95 0.011
response to peptide GO:1901652 136 0.011
regulation of actin polymerization or depolymerization GO:0008064 45 0.011
glycosylation GO:0070085 62 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.011
protein polymerization GO:0051258 57 0.011
positive regulation of apoptotic signaling pathway GO:2001235 95 0.011
positive regulation of stem cell proliferation GO:2000648 59 0.011
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.011
appendage development GO:0048736 166 0.011
Zebrafish
cell division GO:0051301 120 0.011
endodermal cell fate specification GO:0001714 4 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of rho gtpase activity GO:0032319 58 0.011
receptor mediated endocytosis GO:0006898 51 0.011
regulation of embryonic development GO:0045995 71 0.011
histone h3 k9 trimethylation GO:0036124 6 0.011
regulation of zinc ion transport GO:0071579 2 0.011
negative regulation of molecular function GO:0044092 258 0.011
single organism nuclear import GO:1902593 95 0.011
formation of organ boundary GO:0010160 1 0.010
connective tissue development GO:0061448 179 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
gonad development GO:0008406 141 0.010
regulation of stem cell proliferation GO:0072091 78 0.010
positive regulation of gtpase activity GO:0043547 85 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
glycoprotein metabolic process GO:0009100 116 0.010
leukocyte homeostasis GO:0001776 79 0.010
negative regulation of cell activation GO:0050866 111 0.010
learning or memory GO:0007611 148 0.010
ephrin receptor signaling pathway GO:0048013 20 0.010

Trim33 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.142
Human
disease of cellular proliferation DOID:14566 0 0.142
Human
organ system cancer DOID:0050686 0 0.107
Human
thoracic cancer DOID:5093 0 0.067
large intestine cancer DOID:5672 0 0.039
colorectal cancer DOID:9256 0 0.039
colon cancer DOID:219 0 0.039
gastrointestinal system cancer DOID:3119 0 0.039
intestinal cancer DOID:10155 0 0.039
respiratory system cancer DOID:0050615 0 0.025
lung cancer DOID:1324 0 0.025
colon carcinoma DOID:1520 0 0.017
musculoskeletal system disease DOID:17 0 0.013
disease of anatomical entity DOID:7 0 0.013
breast cancer DOID:1612 0 0.011