IMP
Process View
Mus musculus
0 genes annotated in mouse
respiratory system cancer
DOID:0050615
An organ system cancer located in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract.
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Pten | phosphatase and tensin homolog | 0.985 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.755 | Human | |
| Apc | adenomatosis polyposis coli | 0.492 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.468 | ||
| Rb1 | retinoblastoma 1 | 0.366 | Human | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.318 | ||
| Trp53 | transformation related protein 53 | 0.243 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.219 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.192 | ||
| Nf1 | neurofibromatosis 1 | 0.180 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.127 | ||
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.121 | ||
| Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.104 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.087 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.076 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.054 | ||
| Msh2 | mutS homolog 2 (E. coli) | 0.051 | ||
| Kit | kit oncogene | 0.051 | ||
| Braf | Braf transforming gene | 0.046 | Human | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.040 | ||
| Kitl | kit ligand | 0.039 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.038 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.036 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.034 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.031 | ||
| Ptch1 | patched homolog 1 | 0.030 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.027 | ||
| Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.027 | Human | |
| Brca1 | breast cancer 1 | 0.026 | ||
| Trim33 | tripartite motif-containing 33 | 0.025 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.023 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.023 | ||
| Rictor | RPTOR independent companion of MTOR, complex 2 | 0.022 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.022 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.021 | ||
| Stk11 | serine/threonine kinase 11 | 0.021 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.020 | ||
| Chuk | conserved helix-loop-helix ubiquitous kinase | 0.020 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.020 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.020 | ||
| E2f1 | E2F transcription factor 1 | 0.020 | ||
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.019 | ||
| Cdkn2a | cyclin-dependent kinase inhibitor 2A | 0.019 | ||
| Foxo3 | forkhead box O3 | 0.019 | ||
| Egfr | epidermal growth factor receptor | 0.019 | ||
| Psen1 | presenilin 1 | 0.018 | ||
| Atm | ataxia telangiectasia mutated homolog (human) | 0.018 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.017 | ||
| Phox2b | paired-like homeobox 2b | 0.017 | ||
| Raf1 | v-raf-leukemia viral oncogene 1 | 0.017 | ||
| Atp2a2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.016 | ||
| Tsc1 | tuberous sclerosis 1 | 0.016 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.016 | ||
| Dmtf1 | cyclin D binding myb-like transcription factor 1 | 0.015 | ||
| Mecp2 | methyl CpG binding protein 2 | 0.015 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.014 | ||
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.014 | ||
| Nf2 | neurofibromatosis 2 | 0.014 | ||
| Gbp2 | guanylate binding protein 2 | 0.013 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.013 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.013 | ||
| Atf2 | activating transcription factor 2 | 0.013 | ||
| Il27ra | interleukin 27 receptor, alpha | 0.012 | ||
| Pik3cb | phosphatidylinositol 3-kinase, catalytic, beta polypeptide | 0.012 | ||
| Irgm2 | immunity-related GTPase family M member 2 | 0.012 | ||
| Erbb2ip | Erbb2 interacting protein | 0.012 | ||
| Spnb2 | spectrin beta 2 | 0.012 | ||
| Eif2ak3 | eukaryotic translation initiation factor 2 alpha kinase 3 | 0.012 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.012 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.011 | ||
| Nbn | nibrin | 0.011 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.011 | ||
| Itga6 | integrin alpha 6 | 0.011 | ||
| Sav1 | salvador homolog 1 (Drosophila) | 0.011 | ||
| Gbp3 | guanylate binding protein 3 | 0.011 | ||
| Wdr26 | WD repeat domain 26 | 0.011 | ||
| Nras | neuroblastoma ras oncogene | 0.011 | ||
| Gbp7 | guanylate binding protein 7 | 0.011 | ||
| Ret | ret proto-oncogene | 0.011 | ||
| Xpa | xeroderma pigmentosum, complementation group A | 0.010 | ||
| Lyz2 | lysozyme 2 | 0.010 | ||
| Atr | ataxia telangiectasia and Rad3 related | 0.010 | ||
| Trp63 | transformation related protein 63 | 0.010 | ||
| Meox2 | mesenchyme homeobox 2 | 0.010 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.010 |