Mus musculus

85 known processes

Pbx2

pre B-cell leukemia transcription factor 2

(Aliases: AU043397,G17)

Pbx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukocyte differentiation GO:0002521 342 0.308
negative regulation of cell proliferation GO:0008285 296 0.253
myeloid cell differentiation GO:0030099 233 0.228
macromolecule catabolic process GO:0009057 281 0.214
cellular macromolecule catabolic process GO:0044265 206 0.208
regulation of asymmetric cell division GO:0009786 4 0.172
Worm
camera type eye development GO:0043010 266 0.146
Zebrafish
ras protein signal transduction GO:0007265 77 0.144
skeletal system development GO:0001501 356 0.142
Mouse
development of primary sexual characteristics GO:0045137 143 0.138
regionalization GO:0003002 337 0.129
apoptotic signaling pathway GO:0097190 306 0.123
ribonucleoside triphosphate metabolic process GO:0009199 220 0.118
neural tube development GO:0021915 160 0.116
negative regulation of myeloid cell differentiation GO:0045638 38 0.115
regulation of myeloid cell differentiation GO:0045637 96 0.114
lipid localization GO:0010876 126 0.113
Worm
negative regulation of immune system process GO:0002683 209 0.111
histone modification GO:0016570 159 0.111
internal protein amino acid acetylation GO:0006475 42 0.111
regulation of apoptotic signaling pathway GO:2001233 197 0.111
lens development in camera type eye GO:0002088 62 0.111
cellular protein catabolic process GO:0044257 155 0.110
negative regulation of molecular function GO:0044092 258 0.105
male gamete generation GO:0048232 285 0.104
t cell differentiation GO:0030217 174 0.101
regulation of cellular ketone metabolic process GO:0010565 66 0.101
retina development in camera type eye GO:0060041 119 0.099
Zebrafish
translation GO:0006412 93 0.099
spermatogenesis GO:0007283 284 0.097
negative regulation of cell development GO:0010721 169 0.097
Mouse
neural tube formation GO:0001841 108 0.094
appendage morphogenesis GO:0035107 149 0.094
erythrocyte differentiation GO:0030218 88 0.094
nucleoside phosphate metabolic process GO:0006753 338 0.093
cell fate commitment GO:0045165 210 0.086
Worm Fly
neural tube closure GO:0001843 90 0.085
chromatin organization GO:0006325 206 0.084
negative regulation of nervous system development GO:0051961 156 0.083
Mouse
endocytosis GO:0006897 168 0.082
Worm
purine containing compound catabolic process GO:0072523 213 0.082
urogenital system development GO:0001655 261 0.080
Mouse
rho protein signal transduction GO:0007266 32 0.080
nitrogen compound transport GO:0071705 271 0.077
muscle tissue development GO:0060537 308 0.076
Zebrafish
protein modification by small protein conjugation or removal GO:0070647 207 0.075
small gtpase mediated signal transduction GO:0007264 97 0.075
hematopoietic progenitor cell differentiation GO:0002244 143 0.074
purine nucleotide metabolic process GO:0006163 302 0.074
regulation of neuron differentiation GO:0045664 281 0.074
Mouse
defense response to other organism GO:0098542 197 0.073
lymphocyte differentiation GO:0030098 242 0.072
regulation of cellular catabolic process GO:0031329 242 0.071
multicellular organismal reproductive behavior GO:0033057 23 0.070
Worm
embryonic appendage morphogenesis GO:0035113 126 0.068
chromatin modification GO:0016568 187 0.068
histone acetylation GO:0016573 41 0.068
internal peptidyl lysine acetylation GO:0018393 42 0.067
carbohydrate metabolic process GO:0005975 230 0.066
germ cell development GO:0007281 185 0.066
regulation of translation GO:0006417 71 0.065
wnt signaling pathway GO:0016055 188 0.064
response to radiation GO:0009314 165 0.064
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.064
t cell activation GO:0042110 289 0.063
positive regulation of cell development GO:0010720 237 0.063
peptide transport GO:0015833 133 0.063
rhythmic process GO:0048511 174 0.062
regulation of cellular amino acid metabolic process GO:0006521 5 0.062
digestive tract development GO:0048565 190 0.061
Worm
positive regulation of neuron differentiation GO:0045666 141 0.060
cellular homeostasis GO:0019725 240 0.060
peptidyl amino acid modification GO:0018193 336 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.058
retrograde transport endosome to golgi GO:0042147 2 0.058
purine ribonucleotide metabolic process GO:0009150 290 0.058
protein acylation GO:0043543 64 0.057
morphogenesis of a branching epithelium GO:0061138 193 0.057
Mouse
covalent chromatin modification GO:0016569 163 0.057
aromatic compound catabolic process GO:0019439 286 0.056
cation homeostasis GO:0055080 212 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
negative regulation of cellular component organization GO:0051129 194 0.054
nodal signaling pathway GO:0038092 10 0.052
regulation of embryonic development GO:0045995 71 0.052
digestive tract morphogenesis GO:0048546 147 0.052
Worm
organic cyclic compound catabolic process GO:1901361 295 0.051
gonad development GO:0008406 141 0.051
positive regulation of nervous system development GO:0051962 221 0.051
mitotic cell cycle process GO:1903047 159 0.051
Mouse
purine containing compound metabolic process GO:0072521 311 0.051
cellular carbohydrate metabolic process GO:0044262 119 0.050
digestive system development GO:0055123 200 0.050
Worm
guanosine containing compound catabolic process GO:1901069 144 0.049
synaptic transmission GO:0007268 329 0.049
blood circulation GO:0008015 195 0.049
positive regulation of apoptotic process GO:0043065 217 0.049
peptidyl lysine modification GO:0018205 77 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.048
embryonic skeletal system development GO:0048706 120 0.048
Mouse
myeloid cell homeostasis GO:0002262 114 0.047
sensory organ morphogenesis GO:0090596 242 0.047
Zebrafish
positive regulation of transferase activity GO:0051347 167 0.047
carbohydrate homeostasis GO:0033500 128 0.047
regulation of innate immune response GO:0045088 91 0.047
canonical wnt signaling pathway GO:0060070 130 0.046
protein localization to nucleus GO:0034504 121 0.046
Fly
dna metabolic process GO:0006259 303 0.045
intracellular protein transport GO:0006886 204 0.045
Fly
regulation of secretion GO:0051046 274 0.045
regulation of cellular protein catabolic process GO:1903362 61 0.045
cellular chemical homeostasis GO:0055082 215 0.045
multi multicellular organism process GO:0044706 109 0.045
Worm
gtp metabolic process GO:0046039 144 0.045
positive regulation of cellular catabolic process GO:0031331 148 0.045
proteasomal protein catabolic process GO:0010498 98 0.044
organophosphate catabolic process GO:0046434 232 0.044
positive regulation of defense response GO:0031349 124 0.043
embryonic epithelial tube formation GO:0001838 130 0.043
homeostasis of number of cells GO:0048872 210 0.043
regulation of defense response GO:0031347 233 0.042
nuclear transport GO:0051169 139 0.042
Fly
maintenance of location GO:0051235 89 0.042
Worm
cellular amino acid metabolic process GO:0006520 103 0.042
monocarboxylic acid metabolic process GO:0032787 191 0.042
hormone secretion GO:0046879 128 0.041
regulation of kinase activity GO:0043549 249 0.041
angiogenesis GO:0001525 201 0.041
circulatory system process GO:0003013 197 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
lateral inhibition GO:0046331 1 0.040
reproductive behavior GO:0019098 32 0.040
Worm
mitotic cell cycle GO:0000278 195 0.040
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.040
positive regulation of protein kinase b signaling GO:0051897 32 0.040
forebrain development GO:0030900 302 0.039
nephron morphogenesis GO:0072028 69 0.039
Mouse
innate immune response GO:0045087 157 0.039
megakaryocyte differentiation GO:0030219 26 0.039
regulation of lymphocyte activation GO:0051249 240 0.039
cellular amine metabolic process GO:0044106 44 0.039
regulation of cellular response to stress GO:0080135 159 0.038
cellular ketone metabolic process GO:0042180 84 0.037
nucleotide metabolic process GO:0009117 332 0.037
posttranscriptional regulation of gene expression GO:0010608 155 0.037
positive regulation of protein modification process GO:0031401 299 0.037
epithelial tube morphogenesis GO:0060562 303 0.037
Mouse
anion transport GO:0006820 177 0.037
modification dependent protein catabolic process GO:0019941 133 0.037
primary neural tube formation GO:0014020 95 0.036
purine nucleoside catabolic process GO:0006152 205 0.036
regulation of hormone levels GO:0010817 211 0.036
regulation of purine nucleotide metabolic process GO:1900542 169 0.036
neuronal action potential GO:0019228 54 0.036
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.036
amide transport GO:0042886 138 0.035
regulation of organ morphogenesis GO:2000027 144 0.035
regulation of leukocyte differentiation GO:1902105 159 0.035
neural precursor cell proliferation GO:0061351 121 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
skeletal system morphogenesis GO:0048705 203 0.035
mammary gland epithelial cell proliferation GO:0033598 24 0.035
limb development GO:0060173 166 0.035
regulation of ion transport GO:0043269 215 0.035
organic anion transport GO:0015711 137 0.034
gastrulation GO:0007369 116 0.034
Worm
regulation of establishment of protein localization GO:0070201 181 0.034
modification dependent macromolecule catabolic process GO:0043632 133 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
regulation of cell migration GO:0030334 219 0.034
gtp catabolic process GO:0006184 143 0.034
cellular response to organonitrogen compound GO:0071417 145 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.032
regulation of homeostatic process GO:0032844 182 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.032
cyclic nucleotide metabolic process GO:0009187 59 0.032
epithelial tube formation GO:0072175 130 0.032
regulation of binding GO:0051098 111 0.032
tube formation GO:0035148 140 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
protein kinase b signaling GO:0043491 74 0.031
negative regulation of neuron differentiation GO:0045665 101 0.031
Mouse
striated muscle tissue development GO:0014706 293 0.031
Zebrafish
regulation of hormone secretion GO:0046883 88 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
epithelial cell proliferation GO:0050673 174 0.031
histone h4 k16 acetylation GO:0043984 3 0.031
protein import GO:0017038 101 0.031
Fly
fibroblast proliferation GO:0048144 35 0.031
muscle cell differentiation GO:0042692 261 0.030
Zebrafish Worm
nucleotide catabolic process GO:0009166 217 0.030
nucleoside catabolic process GO:0009164 206 0.030
locomotory behavior GO:0007626 195 0.030
Mouse
regulation of peptide transport GO:0090087 91 0.030
cellular response to hormone stimulus GO:0032870 150 0.030
regulation of transferase activity GO:0051338 263 0.030
response to peptide GO:1901652 136 0.030
response to light stimulus GO:0009416 135 0.030
regulation of epithelial cell proliferation GO:0050678 141 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
inorganic ion transmembrane transport GO:0098660 234 0.029
regulation of lymphocyte proliferation GO:0050670 117 0.029
heterocycle catabolic process GO:0046700 280 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
kidney development GO:0001822 213 0.029
Mouse
ribonucleotide metabolic process GO:0009259 291 0.029
embryonic organ morphogenesis GO:0048562 276 0.029
second messenger mediated signaling GO:0019932 73 0.028
axonogenesis GO:0007409 274 0.028
histone h4 acetylation GO:0043967 10 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
positive regulation of kinase activity GO:0033674 155 0.028
vesicle localization GO:0051648 86 0.028
positive regulation of nucleoside metabolic process GO:0045979 91 0.028
peptide hormone secretion GO:0030072 109 0.028
circadian rhythm GO:0007623 114 0.028
regulation of fibroblast proliferation GO:0048145 34 0.028
actin filament polymerization GO:0030041 44 0.027
membrane organization GO:0061024 245 0.027
morphogenesis of a branching structure GO:0001763 203 0.027
Mouse
positive regulation of programmed cell death GO:0043068 218 0.027
stem cell differentiation GO:0048863 268 0.027
defense response to bacterium GO:0042742 119 0.027
tube closure GO:0060606 91 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
synapse organization GO:0050808 125 0.027
regulation of t cell activation GO:0050863 170 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.026
gland development GO:0048732 330 0.026
Mouse
activation of immune response GO:0002253 138 0.026
development of primary male sexual characteristics GO:0046546 88 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
negative regulation of cell cycle GO:0045786 123 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.026
cell adhesion GO:0007155 329 0.026
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.026
interleukin 8 production GO:0032637 4 0.026
sensory perception GO:0007600 245 0.026
regulation of membrane potential GO:0042391 192 0.026
regulation of ras protein signal transduction GO:0046578 114 0.026
regulation of mitotic cell cycle GO:0007346 126 0.026
Mouse
nucleoside metabolic process GO:0009116 246 0.026
regulation of nucleotide metabolic process GO:0006140 169 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
pharynx development GO:0060465 1 0.026
negative regulation of interleukin 8 production GO:0032717 1 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
organic acid transport GO:0015849 101 0.025
regulation of chromatin organization GO:1902275 57 0.025
cation transmembrane transport GO:0098655 266 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
regulation of t cell proliferation GO:0042129 92 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
response to monosaccharide GO:0034284 67 0.025
organelle localization GO:0051640 179 0.025
appendage development GO:0048736 166 0.025
response to organic cyclic compound GO:0014070 198 0.025
response to insulin GO:0032868 100 0.025
methylation GO:0032259 134 0.024
positive regulation of protein export from nucleus GO:0046827 4 0.024
protein import into nucleus GO:0006606 95 0.024
Fly
regulation of mitotic cell cycle phase transition GO:1901990 73 0.024
Mouse
cell fate specification GO:0001708 72 0.024
Worm Fly
purine ribonucleoside catabolic process GO:0046130 205 0.024
inflammatory response GO:0006954 244 0.024
inorganic cation transmembrane transport GO:0098662 207 0.024
mesoderm morphogenesis GO:0048332 64 0.024
Worm
glycosyl compound catabolic process GO:1901658 206 0.024
mesoderm development GO:0007498 100 0.024
Worm
regulation of protein transport GO:0051223 163 0.024
multicellular organism growth GO:0035264 161 0.024
compound eye development GO:0048749 1 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
transmembrane transport GO:0055085 412 0.023
regulation of cell growth GO:0001558 91 0.023
glucose homeostasis GO:0042593 128 0.023
regulation of peptide hormone secretion GO:0090276 75 0.023
carbohydrate biosynthetic process GO:0016051 74 0.023
lymphocyte mediated immunity GO:0002449 139 0.023
regulation of secretion by cell GO:1903530 249 0.023
cell maturation GO:0048469 127 0.023
embryonic limb morphogenesis GO:0030326 126 0.023
cartilage development GO:0051216 140 0.023
ossification GO:0001503 216 0.023
Mouse
lipid storage GO:0019915 36 0.023
Worm
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
regulation of chromatin modification GO:1903308 57 0.023
protein sumoylation GO:0016925 14 0.023
multicellular organismal signaling GO:0035637 91 0.023
regulation of ossification GO:0030278 112 0.023
Mouse
transmission of nerve impulse GO:0019226 76 0.022
cytokine production GO:0001816 319 0.022
mammary gland epithelium development GO:0061180 65 0.022
regulation of protein localization GO:0032880 231 0.022
limb morphogenesis GO:0035108 149 0.022
hindbrain development GO:0030902 128 0.022
regulation of neuron projection development GO:0010975 169 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
positive regulation of cell death GO:0010942 224 0.022
regulation of wnt signaling pathway GO:0030111 123 0.022
cell type specific apoptotic process GO:0097285 268 0.022
positive regulation of leukocyte differentiation GO:1902107 86 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
protein catabolic process GO:0030163 221 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
regulation of intracellular transport GO:0032386 159 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
cytokine metabolic process GO:0042107 71 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
guanosine containing compound metabolic process GO:1901068 144 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.021
regulation of glucose metabolic process GO:0010906 60 0.021
multi organism behavior GO:0051705 62 0.021
Worm
respiratory system development GO:0060541 190 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
positive regulation of fibroblast proliferation GO:0048146 20 0.021
regulation of histone h3 k4 methylation GO:0051569 12 0.021
positive regulation of innate immune response GO:0045089 80 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.021
blood vessel morphogenesis GO:0048514 285 0.021
immune response regulating signaling pathway GO:0002764 125 0.021
adult behavior GO:0030534 135 0.021
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
placenta development GO:0001890 140 0.020
cell cycle g1 s phase transition GO:0044843 57 0.020
receptor mediated endocytosis GO:0006898 51 0.020
Worm
regulation of anatomical structure size GO:0090066 178 0.020
embryonic skeletal system morphogenesis GO:0048704 91 0.020
metal ion homeostasis GO:0055065 189 0.020
action potential GO:0001508 78 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
positive regulation of gtpase activity GO:0043547 85 0.020
chemotaxis GO:0006935 247 0.020
cytoplasmic transport GO:0016482 234 0.020
Fly
establishment of protein localization to membrane GO:0090150 54 0.020
oogenesis GO:0048477 56 0.020
regulation of cell cycle GO:0051726 281 0.020
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.020
t cell proliferation GO:0042098 120 0.020
regulation of hydrolase activity GO:0051336 246 0.020
response to peptide hormone GO:0043434 127 0.020
divalent inorganic cation transport GO:0072511 178 0.020
branching morphogenesis of an epithelial tube GO:0048754 159 0.020
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
cellular response to peptide GO:1901653 92 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
cellular lipid metabolic process GO:0044255 323 0.020
female gamete generation GO:0007292 74 0.020
regulation of interleukin 8 production GO:0032677 3 0.020
spermatid development GO:0007286 108 0.020
lens morphogenesis in camera type eye GO:0002089 24 0.020
positive regulation of protein kinase activity GO:0045860 144 0.019
dna alkylation GO:0006305 43 0.019
sensory perception of pain GO:0019233 47 0.019
palate development GO:0060021 76 0.019
multicellular organismal response to stress GO:0033555 62 0.019
mesenchyme development GO:0060485 152 0.019
positive regulation of cellular protein catabolic process GO:1903364 34 0.019
protein localization to organelle GO:0033365 185 0.019
Fly
spermatid differentiation GO:0048515 115 0.019
regulation of cell activation GO:0050865 289 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
mitochondrion organization GO:0007005 134 0.019
sequestering of metal ion GO:0051238 19 0.019
protein methylation GO:0006479 81 0.019
calcium mediated signaling GO:0019722 46 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
actomyosin structure organization GO:0031032 56 0.019
positive regulation of binding GO:0051099 49 0.018
hair cycle GO:0042633 90 0.018
cellular response to carbohydrate stimulus GO:0071322 50 0.018
striated muscle contraction GO:0006941 45 0.018
neuron projection extension GO:1990138 64 0.018
regulation of vesicle mediated transport GO:0060627 139 0.018
carboxylic acid transport GO:0046942 100 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
regulation of t cell differentiation GO:0045580 83 0.018
response to lipopolysaccharide GO:0032496 128 0.018
photoreceptor cell morphogenesis GO:0008594 3 0.018
cellular ion homeostasis GO:0006873 165 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
endomembrane system organization GO:0010256 147 0.018
lung development GO:0030324 164 0.018
response to oxidative stress GO:0006979 123 0.018
regulation of cardiac cell fate specification GO:2000043 1 0.018
positive regulation of gtp catabolic process GO:0033126 85 0.018
determination of left right symmetry GO:0007368 80 0.018
multi organism reproductive behavior GO:0044705 29 0.018
Worm
forebrain generation of neurons GO:0021872 63 0.018
regulation of circadian rhythm GO:0042752 58 0.017
lymphocyte proliferation GO:0046651 164 0.017
peptidyl threonine phosphorylation GO:0018107 31 0.017
positive regulation of proteolysis GO:0045862 85 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
cation transport GO:0006812 399 0.017
regulation of cell projection organization GO:0031344 206 0.017
cognition GO:0050890 149 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
regulation of protein kinase activity GO:0045859 232 0.017
regulation of osteoclast differentiation GO:0045670 36 0.017
protein ubiquitination GO:0016567 171 0.017
hair follicle development GO:0001942 85 0.017
regulation of myeloid leukocyte differentiation GO:0002761 58 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
regulation of osteoblast differentiation GO:0045667 67 0.017
regulation of system process GO:0044057 200 0.017
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.017
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.017
lipid transport GO:0006869 98 0.017
female sex differentiation GO:0046660 84 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
immune effector process GO:0002252 321 0.017
response to nutrient levels GO:0031667 109 0.017
male sex differentiation GO:0046661 109 0.017
single organism cell adhesion GO:0098602 156 0.016
peptidyl lysine acetylation GO:0018394 45 0.016
ovulation cycle GO:0042698 59 0.016
dipeptide transport GO:0042938 2 0.016
histone lysine methylation GO:0034968 50 0.016
organic acid biosynthetic process GO:0016053 86 0.016
bmp signaling pathway GO:0030509 93 0.016
amine metabolic process GO:0009308 45 0.016
exocytosis GO:0006887 121 0.016
regulation of protein binding GO:0043393 60 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
regulation of transmembrane transport GO:0034762 128 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
dephosphorylation GO:0016311 129 0.016
embryonic digit morphogenesis GO:0042733 56 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.016
regulation of mapk cascade GO:0043408 248 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
pole plasm assembly GO:0007315 2 0.016
embryonic placenta development GO:0001892 98 0.016
lipid homeostasis GO:0055088 63 0.016
body morphogenesis GO:0010171 45 0.016
Worm
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
regulation of canonical wnt signaling pathway GO:0060828 82 0.016
metencephalon development GO:0022037 89 0.016
blastocyst development GO:0001824 80 0.016
response to extracellular stimulus GO:0009991 127 0.016
regulation of multi organism process GO:0043900 111 0.016
regulation of defense response to bacterium GO:1900424 3 0.016
protein alkylation GO:0008213 81 0.016
sulfur compound biosynthetic process GO:0044272 37 0.016
cdc42 protein signal transduction GO:0032488 0 0.015
negative regulation of growth GO:0045926 99 0.015
regulation of cell motility GO:2000145 236 0.015
establishment of organelle localization GO:0051656 122 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.015
response to organonitrogen compound GO:0010243 246 0.015
g1 s transition of mitotic cell cycle GO:0000082 57 0.015
regulation of protein sumoylation GO:0033233 4 0.015
jnk cascade GO:0007254 72 0.015
regulation of histone acetylation GO:0035065 19 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
negative regulation of neuron projection development GO:0010977 50 0.015
muscle system process GO:0003012 141 0.015
developmental programmed cell death GO:0010623 41 0.015
negative regulation of transferase activity GO:0051348 85 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
negative regulation of kinase activity GO:0033673 81 0.015
regulation of organelle organization GO:0033043 289 0.015
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.015
activation of adenylate cyclase activity GO:0007190 4 0.015
epidermis development GO:0008544 187 0.015
megakaryocyte development GO:0035855 15 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
actin filament organization GO:0007015 113 0.015
intracellular receptor signaling pathway GO:0030522 74 0.015
mesonephros development GO:0001823 97 0.015
Mouse
negative regulation of mitotic cell cycle GO:0045930 58 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
negative regulation of cell activation GO:0050866 111 0.014
regulation of cellular component size GO:0032535 121 0.014
oxidation reduction process GO:0055114 342 0.014
cyclic purine nucleotide metabolic process GO:0052652 43 0.014
regulation of cardioblast differentiation GO:0051890 3 0.014
mrna processing GO:0006397 63 0.014
stem cell development GO:0048864 219 0.014
peptide secretion GO:0002790 114 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
placenta blood vessel development GO:0060674 31 0.014
cellular protein complex assembly GO:0043623 116 0.014
adaptive immune response GO:0002250 155 0.014
regulation of cell division GO:0051302 76 0.014
Worm
regulation of cell fate specification GO:0042659 10 0.014
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
regulation of histone modification GO:0031056 56 0.014

Pbx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org