IMP

Process View

Mus musculus

12 genes annotated in mouse

regulation of histone h3 k4 methylation

Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of histone h3 k4 methylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of histone h3 k4 methylation" (in gray)

Name	Description	Probability	Func Analog Organism
Gata4	GATA binding protein 4	0.996	Mouse
Kdm2b	lysine (K)-specific demethylase 2B	0.982
Gata6	GATA binding protein 6	0.971	Mouse
Gata1	GATA binding protein 1	0.948	Mouse
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.869
Rxra	retinoid X receptor alpha	0.842
Dnmt3a	DNA methyltransferase 3A	0.819
Zfpm2	zinc finger protein, multitype 2	0.699
Rnf2	ring finger protein 2	0.695
Tal1	T-cell acute lymphocytic leukemia 1	0.627
Gata5	GATA binding protein 5	0.574	Mouse
Brca2	breast cancer 2	0.538
Rnf44	ring finger protein 44	0.424
Gfi1b	growth factor independent 1B	0.333
Runx1	runt related transcription factor 1	0.323
Klf3	Kruppel-like factor 3 (basic)	0.290
Vegfa	vascular endothelial growth factor A	0.284
Arid1a	AT rich interactive domain 1A (SWI-like)	0.252
Ezh2	enhancer of zeste homolog 2 (Drosophila)	0.249
Trrap	transformation/transcription domain-associated protein	0.233
Sox4	SRY-box containing gene 4	0.214
Jag1	jagged 1	0.214
Sin3a	transcriptional regulator, SIN3A (yeast)	0.186
Atm	ataxia telangiectasia mutated homolog (human)	0.179
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.177
Crebbp	CREB binding protein	0.146
Atr	ataxia telangiectasia and Rad3 related	0.145
Zfp592	zinc finger protein 592	0.143
Fbrs	fibrosin	0.140
Hells	helicase, lymphoid specific	0.138
Casc3	cancer susceptibility candidate 3	0.138
Jarid2	jumonji, AT rich interactive domain 2	0.129
Pcnxl3	pecanex-like 3 (Drosophila)	0.126
Notch1	Notch gene homolog 1 (Drosophila)	0.109
Myb	myeloblastosis oncogene	0.108	Human
Wbp7	WW domain binding protein 7	0.104
Spna1	spectrin alpha 1	0.091
Pou5f1	POU domain, class 5, transcription factor 1	0.090
Sept9	septin 9	0.089
Spen	SPEN homolog, transcriptional regulator (Drosophila)	0.088
Pax2	paired box gene 2	0.087
Clk2	CDC-like kinase 2	0.083
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.080
Msl1	male-specific lethal 1 homolog (Drosophila)	0.077
Hdac1	histone deacetylase 1	0.074
Phrf1	PHD and ring finger domains 1	0.072
Zfpm1	zinc finger protein, multitype 1	0.071
Leo1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.070
Cic	capicua homolog (Drosophila)	0.062
Numa1	nuclear mitotic apparatus protein 1	0.061
Ppara	peroxisome proliferator activated receptor alpha	0.059
Isl1	ISL1 transcription factor, LIM/homeodomain	0.058
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.055
Pitx2	paired-like homeodomain transcription factor 2	0.053
Smad4	MAD homolog 4 (Drosophila)	0.052
Rybp	RING1 and YY1 binding protein	0.050
Nbn	nibrin	0.048
Tbx3	T-box 3	0.047
Brpf1	bromodomain and PHD finger containing, 1	0.046
Ncoa6	nuclear receptor coactivator 6	0.045
Slc38a5	solute carrier family 38, member 5	0.044
Brd4	bromodomain containing 4	0.044
Epor	erythropoietin receptor	0.043
Srrm1	serine/arginine repetitive matrix 1	0.043
Pom121	nuclear pore membrane protein 121	0.042
Zfp740	zinc finger protein 740	0.042
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.040
Atxn7l3	ataxin 7-like 3	0.038
Clk4	CDC like kinase 4	0.038
D4Wsu53e	DNA segment, Chr 4, Wayne State University 53, expressed	0.037
Rhag	Rhesus blood group-associated A glycoprotein	0.037
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.037
Safb2	scaffold attachment factor B2	0.036
Taf4a	TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.036
Hand2	heart and neural crest derivatives expressed transcript 2	0.036
Srrt	serrate RNA effector molecule homolog (Arabidopsis)	0.036
Zc3h18	zinc finger CCCH-type containing 18	0.036
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.034
Cbx8	chromobox homolog 8 (Drosophila Pc class)	0.033
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.032
2810046L04Rik	RIKEN cDNA 2810046L04 gene	0.031
Gp9	glycoprotein 9 (platelet)	0.031
Mlxip	MLX interacting protein	0.031
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.031
Muc13	mucin 13, epithelial transmembrane	0.031
Lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.031
Rbbp4	retinoblastoma binding protein 4	0.030
Smad6	MAD homolog 6 (Drosophila)	0.030
Srsf4	serine/arginine-rich splicing factor 4	0.030
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.029
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.028
Plac1	placental specific protein 1	0.028
Med1	mediator complex subunit 1	0.028
Wt1	Wilms tumor 1 homolog	0.028
Brd8	bromodomain containing 8	0.028
Ilf3	interleukin enhancer binding factor 3	0.028
Ctdp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	0.028
Tbx20	T-box 20	0.027
Pold3	polymerase (DNA-directed), delta 3, accessory subunit	0.027
Crebzf	CREB/ATF bZIP transcription factor	0.027
Mbd6	methyl-CpG binding domain protein 6	0.027
Hexim1	hexamethylene bis-acetamide inducible 1	0.026
Rfwd3	ring finger and WD repeat domain 3	0.026
Rere	arginine glutamic acid dipeptide (RE) repeats	0.026
Xpo6	exportin 6	0.026
Cbx2	chromobox homolog 2 (Drosophila Pc class)	0.026
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.025
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.025
Inhba	inhibin beta-A	0.025
Paf1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.025
Eif4a2	eukaryotic translation initiation factor 4A2	0.025
Mdm2	transformed mouse 3T3 cell double minute 2	0.025
Ssbp2	single-stranded DNA binding protein 2	0.024
Ehmt1	euchromatic histone methyltransferase 1	0.024
Med13l	mediator complex subunit 13-like	0.024
Hr	hairless	0.024
Tnrc6c	trinucleotide repeat containing 6C	0.024
Zfp598	zinc finger protein 598	0.023
Clk1	CDC-like kinase 1	0.023
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.023
Ddx17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.022
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.022
4833420G17Rik	RIKEN cDNA 4833420G17 gene	0.022
Mesp1	mesoderm posterior 1	0.022
Scrib	scribbled homolog (Drosophila)	0.022
Rbm22	RNA binding motif protein 22	0.022
Rnps1	ribonucleic acid binding protein S1	0.022
Gypa	glycophorin A	0.022
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.021
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.021
Kdm1a	lysine (K)-specific demethylase 1A	0.021
Pbx2	pre B-cell leukemia transcription factor 2	0.021
Lef1	lymphoid enhancer binding factor 1	0.021
Klf1	Kruppel-like factor 1 (erythroid)	0.021
Fnbp4	formin binding protein 4	0.020
Ank1	ankyrin 1, erythroid	0.020
Tgfb2	transforming growth factor, beta 2	0.020
Foxf1a	forkhead box F1a	0.020
Ncoa5	nuclear receptor coactivator 5	0.019
Gga3	golgi associated, gamma adaptin ear containing, ARF binding protein 3	0.019
Gon4l	gon-4-like (C.elegans)	0.019
Psma1	proteasome (prosome, macropain) subunit, alpha type 1	0.019
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.018
Hemgn	hemogen	0.018
Ltf	lactotransferrin	0.018
Tbc1d10b	TBC1 domain family, member 10b	0.018
Atxn2l	ataxin 2-like	0.017
Cdc42se1	CDC42 small effector 1	0.017
Rcor2	REST corepressor 2	0.017
Asxl1	additional sex combs like 1 (Drosophila)	0.017
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.017
Trp53	transformation related protein 53	0.017
Sfswap	splicing factor, suppressor of white-apricot homolog (Drosophila)	0.016
Ccnl2	cyclin L2	0.016
Fgf8	fibroblast growth factor 8	0.016
Midn	midnolin	0.016
Patz1	POZ (BTB) and AT hook containing zinc finger 1	0.016
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.016
Upk3b	uroplakin 3B	0.016
Timeless	timeless homolog (Drosophila)	0.016
Gigyf1	GRB10 interacting GYF protein 1	0.016
Nfya	nuclear transcription factor-Y alpha	0.015
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.015
Tspo2	translocator protein 2	0.015
2310021P13Rik	RIKEN cDNA 2310021P13 gene	0.015
Sct	secretin	0.015
9430025N12Rik	RIKEN cDNA 9430025N12 gene	0.015
Csnk2a2	casein kinase 2, alpha prime polypeptide	0.015
Fam193b	family with sequence similarity 193, member B	0.015
Trim28	tripartite motif-containing 28	0.014
Rhd	Rh blood group, D antigen	0.014
S1pr2	sphingosine-1-phosphate receptor 2	0.014
Setd1b	SET domain containing 1B	0.014
Daxx	Fas death domain-associated protein	0.014
Med23	mediator complex subunit 23	0.014
Setdb1	SET domain, bifurcated 1	0.014
Sf1	splicing factor 1	0.014
Slc4a2	solute carrier family 4 (anion exchanger), member 2	0.014
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.013
Myl7	myosin, light polypeptide 7, regulatory	0.013
Ylpm1	YLP motif containing 1	0.013
Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.013
Tcf7	transcription factor 7, T-cell specific	0.013
Orc1	origin recognition complex, subunit 1	0.013
Gramd1a	GRAM domain containing 1A	0.013
Parp1	poly (ADP-ribose) polymerase family, member 1	0.013
Mtf2	metal response element binding transcription factor 2	0.013
Phc2	polyhomeotic-like 2 (Drosophila)	0.013
Bnc1	basonuclin 1	0.013
Tle3	transducin-like enhancer of split 3, homolog of Drosophila E(spl)	0.013
Tia1	cytotoxic granule-associated RNA binding protein 1	0.013
Brd3	bromodomain containing 3	0.013
Eml3	echinoderm microtubule associated protein like 3	0.012
Bahd1	bromo adjacent homology domain containing 1	0.012
Sap130	Sin3A associated protein	0.012
Foxp1	forkhead box P1	0.012
Ihh	Indian hedgehog	0.012
Trfr2	transferrin receptor 2	0.012
Kiss1	KiSS-1 metastasis-suppressor	0.012
Usf2	upstream transcription factor 2	0.012
Trp53bp1	transformation related protein 53 binding protein 1	0.012
Apc	adenomatosis polyposis coli	0.012
Dcaf7	DDB1 and CUL4 associated factor 7	0.012
Rcor3	REST corepressor 3	0.012
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.012
Crtc2	CREB regulated transcription coactivator 2	0.012
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.012
Kel	Kell blood group	0.012
Bap1	Brca1 associated protein 1	0.012
Hmgxb3	HMG box domain containing 3	0.011
Kitl	kit ligand	0.011
Cdan1	congenital dyserythropoietic anemia, type I (human)	0.011
Edc4	enhancer of mRNA decapping 4	0.011
Gpatch8	G patch domain containing 8	0.011
Blmh	bleomycin hydrolase	0.011
Cnot6l	CCR4-NOT transcription complex, subunit 6-like	0.011
2610039C10Rik	RIKEN cDNA 2610039C10 gene	0.011
Sgol1	shugoshin-like 1 (S. pombe)	0.011
Ewsr1	Ewing sarcoma breakpoint region 1	0.011
Morc2a	microrchidia 2A	0.011
Cramp1l	Crm, cramped-like (Drosophila)	0.011
Gpr97	G protein-coupled receptor 97	0.011
Mdc1	mediator of DNA damage checkpoint 1	0.011	Mouse
2510039O18Rik	RIKEN cDNA 2510039O18 gene	0.011
9030409G11Rik	RIKEN cDNA 9030409G11 gene	0.011
Hand1	heart and neural crest derivatives expressed transcript 1	0.011
Axin2	axin2	0.011
Foxa3	forkhead box A3	0.011
Vhl	von Hippel-Lindau tumor suppressor	0.011
Trp63	transformation related protein 63	0.011
Ubtf	upstream binding transcription factor, RNA polymerase I	0.011
Ar	androgen receptor	0.010
Tmprss2	transmembrane protease, serine 2	0.010
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.010
Dlk1	delta-like 1 homolog (Drosophila)	0.010
Stat6	signal transducer and activator of transcription 6	0.010
Upf1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.010
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.010
Lig1	ligase I, DNA, ATP-dependent	0.010
Acin1	apoptotic chromatin condensation inducer 1	0.010
Mpo	myeloperoxidase	0.010
Atf7ip	activating transcription factor 7 interacting protein	0.010