|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.804
|
Rat |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.796
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.788
|
Rat |
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.769
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.763
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.744
|
Rat |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.718
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.703
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.682
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.679
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.669
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.667
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.650
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.650
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.648
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.615
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.608
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.606
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.598
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.591
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.571
|
Rat |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.559
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.554
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.548
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.547
|
Rat |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.536
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.518
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.517
|
Rat |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.508
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.492
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.477
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.466
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.463
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.457
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.445
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.444
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.426
|
Rat |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.423
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.419
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.415
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.411
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.409
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.391
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.381
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.380
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.379
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.375
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.374
|
Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.368
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.361
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.361
|
Rat |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.356
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.355
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.354
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.347
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.346
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.345
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.344
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.331
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.329
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.326
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.321
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.320
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.316
|
Rat |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.313
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.310
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.306
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.299
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.290
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.282
|
Rat |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.279
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.277
|
Rat |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.275
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.273
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.270
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.270
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.268
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.264
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.260
|
Human |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.258
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.255
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.254
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.245
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.236
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.233
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.232
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.230
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.230
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
8 |
0.230
|
Rat |
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.230
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.229
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.229
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.228
|
Rat |
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.227
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.227
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.225
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.221
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.220
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.216
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.211
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.206
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.204
|
Human |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.204
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.204
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.200
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.199
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.196
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.193
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.192
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.191
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.191
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.188
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.185
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.182
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.181
|
Rat |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.180
|
Human |
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.179
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.178
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.177
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.177
|
Rat |
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.176
|
Rat |
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.174
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.174
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.173
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.172
|
Rat |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.171
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.170
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.170
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.169
|
Rat |
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.168
|
Rat |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.166
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.166
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.165
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.163
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.162
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.162
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.160
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.160
|
Rat |
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.160
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.157
|
Rat |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.156
|
Rat |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.154
|
|
|
|
nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070427 |
5 |
0.150
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.150
|
|
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.147
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.147
|
Human |
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.146
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.145
|
Rat |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.144
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.144
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.143
|
Rat |
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.143
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.142
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.141
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.140
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.139
|
|
|
|
marginal zone b cell differentiation
|
GO:0002315 |
2 |
0.139
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.137
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.135
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.135
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.133
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.132
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.131
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.131
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.128
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.128
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.128
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.128
|
Human |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.128
|
|
|
|
response to low density lipoprotein particle
|
GO:0055098 |
2 |
0.126
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.126
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.126
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.125
|
Human |
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.124
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.122
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.121
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.121
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.121
|
Rat |
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.121
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.121
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.120
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.119
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.118
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.118
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.116
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.116
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.115
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.115
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.114
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.113
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.113
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.112
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.111
|
Rat |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.111
|
Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.110
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.109
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.109
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.109
|
Human |
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.107
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.106
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.106
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.106
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.105
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.105
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.105
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.104
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.104
|
|
|
|
antimicrobial peptide secretion
|
GO:0002776 |
1 |
0.104
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.104
|
Rat |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.103
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.103
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.102
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.102
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.101
|
Rat |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.101
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.101
|
Rat |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.100
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.100
|
Rat |
|
|
cartilage development
|
GO:0051216 |
140 |
0.099
|
|
|
|
peptide biosynthetic process
|
GO:0043043 |
11 |
0.099
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.098
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.097
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.095
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.094
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.094
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.094
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.092
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.090
|
Rat |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.090
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.089
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.089
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.089
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.089
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.089
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.088
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.087
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.087
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.087
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.087
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.087
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.086
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.086
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.085
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.085
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.085
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.085
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.085
|
Rat |
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.085
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.084
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.084
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.084
|
Rat |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.083
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.083
|
Human |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.083
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.083
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.083
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.082
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.082
|
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.082
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.082
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.081
|
Human |
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.081
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.080
|
Rat |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.079
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.079
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.078
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.078
|
Rat |
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.078
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.078
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.078
|
Human |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.077
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.077
|
Rat |
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.076
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.076
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.075
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.075
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.075
|
Rat |
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.073
|
Rat |
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.073
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.073
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
35 |
0.073
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.073
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.073
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.073
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.072
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.072
|
|
|
|
interaction with host
|
GO:0051701 |
22 |
0.072
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.072
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.071
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.071
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.070
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.070
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.069
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.069
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.069
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.069
|
Rat |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.069
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.069
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.069
|
Rat |
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.069
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.067
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.067
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.067
|
Rat |
|
|
chemokine production
|
GO:0032602 |
34 |
0.066
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.066
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.066
|
Human |
|
|
response to protozoan
|
GO:0001562 |
28 |
0.066
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.066
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.066
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.066
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.065
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.064
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.064
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.064
|
Rat |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.064
|
Rat |
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.064
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.064
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.064
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.064
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.064
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.062
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.062
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.062
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.061
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.060
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.060
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.060
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.060
|
Rat |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.060
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
28 |
0.060
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.060
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
19 |
0.060
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.059
|
|
|
|
dendritic cell migration
|
GO:0036336 |
12 |
0.059
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.059
|
Rat |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.058
|
Rat |
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.058
|
|
|
|
regulation of b cell apoptotic process
|
GO:0002902 |
13 |
0.058
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.058
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.058
|
|
|
|
negative regulation of tumor necrosis factor biosynthetic process
|
GO:0042536 |
1 |
0.057
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.057
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.057
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.057
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.057
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.056
|
|
|
|
positive regulation of interleukin 10 biosynthetic process
|
GO:0045082 |
1 |
0.056
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.056
|
Rat |
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.055
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.055
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.055
|
Rat |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.055
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.055
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.054
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.054
|
Rat |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.054
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.053
|
|
|
|
response to hyperoxia
|
GO:0055093 |
2 |
0.053
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.053
|
Human |
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.053
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.053
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.053
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.052
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.052
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.052
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.052
|
Rat |
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.051
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.051
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.051
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.051
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.050
|
Human |
|
|
germinal center formation
|
GO:0002467 |
16 |
0.050
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.050
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.050
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.050
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.050
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.049
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.049
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.049
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.048
|
Rat |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.048
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.048
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.048
|
Rat |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.048
|
Rat |
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.047
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.046
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.046
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.046
|
Rat |
|
|
anion transport
|
GO:0006820 |
177 |
0.046
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.046
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.045
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.045
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.045
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.045
|
|
|
|
regulation of intrinsic apoptotic signaling pathway in response to dna damage
|
GO:1902229 |
14 |
0.045
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.045
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.045
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.045
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.044
|
Rat |
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.044
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.044
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.044
|
Rat |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.044
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.044
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.044
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.044
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
6 |
0.044
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.044
|
Rat |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.043
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.043
|
Rat |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.043
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.042
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.042
|
Rat |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.042
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.042
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.042
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.042
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.042
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.041
|
Rat |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.041
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.041
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.041
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.041
|
Rat |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.040
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.040
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.040
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.040
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.040
|
Rat |
|
|
placenta development
|
GO:0001890 |
140 |
0.040
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.039
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.039
|
Rat |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.039
|
Rat |
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.039
|
|
|
|
leukocyte aggregation
|
GO:0070486 |
1 |
0.039
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.038
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.038
|
Rat |
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.038
|
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.038
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.038
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.038
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.038
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.038
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.038
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.038
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.038
|
Rat |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.037
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.037
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
72 |
0.037
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.037
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.037
|
Human |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.037
|
Rat |
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.037
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.036
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.036
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.036
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.036
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.036
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.036
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.036
|
Rat |
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.036
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.036
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.036
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.036
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.035
|
|
|
|
dendritic cell dendrite assembly
|
GO:0097026 |
2 |
0.035
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.035
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.035
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.035
|
Human |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.035
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.034
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.034
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.034
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.034
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.034
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.034
|
|
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.034
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.034
|
Rat |
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.034
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.034
|
Rat |
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.034
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.034
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.033
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.033
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.033
|
Rat |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.033
|
Rat |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.033
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.032
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.032
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.032
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.032
|
Rat |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.032
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
36 |
0.032
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.032
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.032
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.032
|
Rat |
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.032
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.031
|
Rat |
