IMP

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Mus musculus

17 genes annotated in mouse

Multi-species View

regulation of t helper 1 type immune response

GO:0002825

Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t helper 1 type immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t helper 1 type immune response" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl2	chemokine (C-C motif) ligand 2	0.897
Ccr1	chemokine (C-C motif) receptor 1	0.840	Mouse
Ccr2	chemokine (C-C motif) receptor 2	0.720
Ikzf1	IKAROS family zinc finger 1	0.645
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.617	Mouse
Cd44	CD44 antigen	0.582
Il1b	interleukin 1 beta	0.574
Ccl3	chemokine (C-C motif) ligand 3	0.565	Mouse
Ccl4	chemokine (C-C motif) ligand 4	0.557	Mouse
Selp	selectin, platelet	0.532
Batf	basic leucine zipper transcription factor, ATF-like	0.515
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.488
Socs3	suppressor of cytokine signaling 3	0.469	Mouse
Jak2	Janus kinase 2	0.451	Mouse
Ifng	interferon gamma	0.401
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.370	Mouse
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.360
Tnf	tumor necrosis factor	0.309
Socs1	suppressor of cytokine signaling 1	0.291	Mouse
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.280
Lyz2	lysozyme 2	0.275
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.239
Icam1	intercellular adhesion molecule 1	0.232
Itgax	integrin alpha X	0.222
Ccl8	chemokine (C-C motif) ligand 8	0.221
Foxp3	forkhead box P3	0.220
Il1rl1	interleukin 1 receptor-like 1	0.220
Il18rap	interleukin 18 receptor accessory protein	0.214	Mouse
Pdcd1	programmed cell death 1	0.211
Il1r1	interleukin 1 receptor, type I	0.203	Mouse
C1qb	complement component 1, q subcomponent, beta polypeptide	0.197
Lepr	leptin receptor	0.187
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.187
Ccr5	chemokine (C-C motif) receptor 5	0.186	Mouse
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.184
Ctsw	cathepsin W	0.181
Lta	lymphotoxin A	0.171
C3ar1	complement component 3a receptor 1	0.168
Ciita	class II transactivator	0.164
Fas	Fas (TNF receptor superfamily member 6)	0.154
Ccl12	chemokine (C-C motif) ligand 12	0.141	Mouse
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.139
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.136
Il12rb2	interleukin 12 receptor, beta 2	0.131	Mouse
Cish	cytokine inducible SH2-containing protein	0.127	Mouse
Ccl22	chemokine (C-C motif) ligand 22	0.119
Il2rb	interleukin 2 receptor, beta chain	0.117
Cd180	CD180 antigen	0.116
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.113
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.111
Cxcl13	chemokine (C-X-C motif) ligand 13	0.111
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.107
Il6	interleukin 6	0.105
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.103
Ccr7	chemokine (C-C motif) receptor 7	0.102	Mouse
Prdm1	PR domain containing 1, with ZNF domain	0.100
Il10ra	interleukin 10 receptor, alpha	0.099
Cd86	CD86 antigen	0.097
Il27ra	interleukin 27 receptor, alpha	0.097
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.096
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.095
Cd40	CD40 antigen	0.093
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.092
Mmp3	matrix metallopeptidase 3	0.091
Lag3	lymphocyte-activation gene 3	0.087
Cd7	CD7 antigen	0.087
Il1rn	interleukin 1 receptor antagonist	0.085
Stat3	signal transducer and activator of transcription 3	0.085
Ubd	ubiquitin D	0.079
Cxcl2	chemokine (C-X-C motif) ligand 2	0.078
Cxcr2	chemokine (C-X-C motif) receptor 2	0.076	Mouse
Bcl3	B-cell leukemia/lymphoma 3	0.073
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.073
Ptprc	protein tyrosine phosphatase, receptor type, C	0.070
Stat5a	signal transducer and activator of transcription 5A	0.069
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.067
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.067
Sh2d2a	SH2 domain protein 2A	0.066
Mmp12	matrix metallopeptidase 12	0.065
Ch25h	cholesterol 25-hydroxylase	0.063
C5ar1	complement component 5a receptor 1	0.063
Clec4d	C-type lectin domain family 4, member d	0.062
Mefv	Mediterranean fever	0.061
Bdkrb1	bradykinin receptor, beta 1	0.061
Il7r	interleukin 7 receptor	0.060
Tcra	T-cell receptor alpha chain	0.060
Nlrp3	NLR family, pyrin domain containing 3	0.059	Mouse
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.058
Itgal	integrin alpha L	0.058
Il6st	interleukin 6 signal transducer	0.055	Mouse
Irf5	interferon regulatory factor 5	0.055
Gpr132	G protein-coupled receptor 132	0.051
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.048
Ptgir	prostaglandin I receptor (IP)	0.048
Fcgr1	Fc receptor, IgG, high affinity I	0.047
Irf1	interferon regulatory factor 1	0.047
Itk	IL2-inducible T-cell kinase	0.045
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.045
Mmp8	matrix metallopeptidase 8	0.045
Folr2	folate receptor 2 (fetal)	0.045
Pdcd1lg2	programmed cell death 1 ligand 2	0.043
Gzmb	granzyme B	0.042
Icos	inducible T-cell co-stimulator	0.042
Cd6	CD6 antigen	0.041
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.040
Vcam1	vascular cell adhesion molecule 1	0.039
Rasal3	RAS protein activator like 3	0.039
Gzmc	granzyme C	0.039
Gzmk	granzyme K	0.038
Cd3e	CD3 antigen, epsilon polypeptide	0.038
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.038
Xcl1	chemokine (C motif) ligand 1	0.037
Ccl7	chemokine (C-C motif) ligand 7	0.036	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.036
Cxcl9	chemokine (C-X-C motif) ligand 9	0.035
Ifngr1	interferon gamma receptor 1	0.034
Cd4	CD4 antigen	0.034
Msr1	macrophage scavenger receptor 1	0.033
Il18r1	interleukin 18 receptor 1	0.033	Mouse
S1pr4	sphingosine-1-phosphate receptor 4	0.031
Tbx21	T-box 21	0.031
Itgb2	integrin beta 2	0.031
Ccr6	chemokine (C-C motif) receptor 6	0.031	Mouse
Gzma	granzyme A	0.030
Gpr33	G protein-coupled receptor 33	0.030
Tgfb1	transforming growth factor, beta 1	0.030
Ltb	lymphotoxin B	0.029
Slpi	secretory leukocyte peptidase inhibitor	0.029
Pim1	proviral integration site 1	0.028
2410004A20Rik	RIKEN cDNA 2410004A20 gene	0.028
Socs2	suppressor of cytokine signaling 2	0.028	Mouse
Fasl	Fas ligand (TNF superfamily, member 6)	0.028
Egfr	epidermal growth factor receptor	0.028
Ncr1	natural cytotoxicity triggering receptor 1	0.028
Cd2	CD2 antigen	0.027
Ccl17	chemokine (C-C motif) ligand 17	0.026	Mouse
Clec4e	C-type lectin domain family 4, member e	0.026
Cd80	CD80 antigen	0.026
Cxcl5	chemokine (C-X-C motif) ligand 5	0.026
Has1	hyaluronan synthase1	0.026
Ggt5	gamma-glutamyltransferase 5	0.026
Cd160	CD160 antigen	0.026
Slfn1	schlafen 1	0.026
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.025
Il1a	interleukin 1 alpha	0.025
Il2ra	interleukin 2 receptor, alpha chain	0.024
Itgae	integrin alpha E, epithelial-associated	0.024
Adam8	a disintegrin and metallopeptidase domain 8	0.024
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.024
Hbb-b1	hemoglobin, beta adult major chain	0.023
Cxcr3	chemokine (C-X-C motif) receptor 3	0.023	Mouse
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.023
Sele	selectin, endothelial cell	0.023
Tlr7	toll-like receptor 7	0.022
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.022
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.022
Slfn4	schlafen 4	0.022
Irg1	immunoresponsive gene 1	0.022
Sfpi1	SFFV proviral integration 1	0.022
Traf6	TNF receptor-associated factor 6	0.021
Stat6	signal transducer and activator of transcription 6	0.021
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.021
Runx1	runt related transcription factor 1	0.021
Itgam	integrin alpha M	0.021
Il33	interleukin 33	0.020
Slamf8	SLAM family member 8	0.020
Ifitm6	interferon induced transmembrane protein 6	0.020
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.020
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.020
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.020
Brwd3	bromodomain and WD repeat domain containing 3	0.019
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.019
Elk4	ELK4, member of ETS oncogene family	0.019
AF251705	cDNA sequence AF251705	0.019
Cxcl1	chemokine (C-X-C motif) ligand 1	0.019
Casp8	caspase 8	0.018
Fgf7	fibroblast growth factor 7	0.018
Tbxas1	thromboxane A synthase 1, platelet	0.018
Mx2	myxovirus (influenza virus) resistance 2	0.018
C78513	EST C78513	0.018
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.018
Sell	selectin, lymphocyte	0.018
Cyld	cylindromatosis (turban tumor syndrome)	0.018
Spna1	spectrin alpha 1	0.017
Il4ra	interleukin 4 receptor, alpha	0.017
Ccl9	chemokine (C-C motif) ligand 9	0.017	Mouse
Phospho1	phosphatase, orphan 1	0.017
Ccrl2	chemokine (C-C motif) receptor-like 2	0.017	Mouse
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.017
Gm14548	predicted gene 14548	0.017
Il1rap	interleukin 1 receptor accessory protein	0.016	Mouse
Il2rg	interleukin 2 receptor, gamma chain	0.016
Cul5	cullin 5	0.016
Havcr2	hepatitis A virus cellular receptor 2	0.016
Cd5	CD5 antigen	0.016
Ptpn2	protein tyrosine phosphatase, non-receptor type 2	0.016
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.016
Inpp5d	inositol polyphosphate-5-phosphatase D	0.016
Gpr97	G protein-coupled receptor 97	0.015
Cd8a	CD8 antigen, alpha chain	0.015
Il1r2	interleukin 1 receptor, type II	0.015	Mouse
Clec7a	C-type lectin domain family 7, member a	0.015
Srms	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	0.015
Cd96	CD96 antigen	0.015
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.014
Flt3	FMS-like tyrosine kinase 3	0.014
Lif	leukemia inhibitory factor	0.014
Ccl5	chemokine (C-C motif) ligand 5	0.014	Mouse
H2-Eb2	histocompatibility 2, class II antigen E beta2	0.014
Irf4	interferon regulatory factor 4	0.014
Il21r	interleukin 21 receptor	0.014
Tfrc	transferrin receptor	0.014
Plek	pleckstrin	0.014
Itgb7	integrin beta 7	0.013
Rhoh	ras homolog gene family, member H	0.013
Epb4.1	erythrocyte protein band 4.1	0.013
Niacr1	niacin receptor 1	0.013
Myo1f	myosin IF	0.013
Gfpt2	glutamine fructose-6-phosphate transaminase 2	0.013
Il10	interleukin 10	0.013
Cma1	chymase 1, mast cell	0.013
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.013
Rel	reticuloendotheliosis oncogene	0.013
Cd28	CD28 antigen	0.013
Dock1	dedicator of cytokinesis 1	0.013
Birc3	baculoviral IAP repeat-containing 3	0.012
Ifnar1	interferon (alpha and beta) receptor 1	0.012
Foxn1	forkhead box N1	0.012
Il17a	interleukin 17A	0.012
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.012
Cd5l	CD5 antigen-like	0.012
Fgf21	fibroblast growth factor 21	0.012
H2-M9	histocompatibility 2, M region locus 9	0.012
Ccl20	chemokine (C-C motif) ligand 20	0.012
Selplg	selectin, platelet (p-selectin) ligand	0.012
Wisp2	WNT1 inducible signaling pathway protein 2	0.012
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.012
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.011
Traf1	TNF receptor-associated factor 1	0.011
Sh2b1	SH2B adaptor protein 1	0.011
Il15ra	interleukin 15 receptor, alpha chain	0.011
Sit1	suppression inducing transmembrane adaptor 1	0.011
Apod	apolipoprotein D	0.011
Mmp9	matrix metallopeptidase 9	0.011
Gimap7	GTPase, IMAP family member 7	0.011
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.011
A4galt	alpha 1,4-galactosyltransferase	0.011
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.011
Hba-a1	hemoglobin alpha, adult chain 1	0.011
Snx20	sorting nexin 20	0.011
Cd3d	CD3 antigen, delta polypeptide	0.011
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.010
Dok2	docking protein 2	0.010
Hhex	hematopoietically expressed homeobox	0.010
Il3ra	interleukin 3 receptor, alpha chain	0.010
Clec4n	C-type lectin domain family 4, member n	0.010
Crtam	cytotoxic and regulatory T cell molecule	0.010
Il4	interleukin 4	0.010
C1qc	complement component 1, q subcomponent, C chain	0.010
Chrne	cholinergic receptor, nicotinic, epsilon polypeptide	0.010
Cxcl10	chemokine (C-X-C motif) ligand 10	0.010
Soat2	sterol O-acyltransferase 2	0.010