Mus musculus

0 known processes

G6pd2

glucose-6-phosphate dehydrogenase 2

(Aliases: Gpd-2,G6pdx-ps1,Gpd2)

G6pd2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of interleukin 13 secretion GO:2000665 2 0.135
interleukin 5 secretion GO:0072603 2 0.074
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
oxidation reduction process GO:0055114 342 0.060
macromolecule catabolic process GO:0009057 281 0.059
negative regulation of protein metabolic process GO:0051248 282 0.058
regulation of defense response GO:0031347 233 0.056
apoptotic signaling pathway GO:0097190 306 0.053
negative regulation of immune system process GO:0002683 209 0.053
myeloid cell differentiation GO:0030099 233 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.050
leukocyte differentiation GO:0002521 342 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
cellular amine metabolic process GO:0044106 44 0.044
homeostasis of number of cells GO:0048872 210 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.043
cytokine production GO:0001816 319 0.042
cellular ketone metabolic process GO:0042180 84 0.042
cellular amino acid metabolic process GO:0006520 103 0.041
regulation of response to wounding GO:1903034 189 0.041
membrane organization GO:0061024 245 0.041
inflammatory response GO:0006954 244 0.041
innate immune response GO:0045087 157 0.040
cellular lipid metabolic process GO:0044255 323 0.040
negative regulation of interleukin 5 production GO:0032714 4 0.039
response to radiation GO:0009314 165 0.038
negative regulation of cellular amine metabolic process GO:0033239 1 0.038
regulation of organelle organization GO:0033043 289 0.037
cellular response to lipid GO:0071396 145 0.037
regulation of lymphocyte activation GO:0051249 240 0.036
negative regulation of interleukin 13 secretion GO:2000666 1 0.035
small molecule biosynthetic process GO:0044283 132 0.034
interleukin 13 secretion GO:0072611 2 0.033
negative regulation of t cell activation GO:0050868 65 0.033
amine metabolic process GO:0009308 45 0.033
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.032
regulation of cell activation GO:0050865 289 0.032
regulation of membrane potential GO:0042391 192 0.031
response to organonitrogen compound GO:0010243 246 0.031
regulation of interleukin 5 secretion GO:2000662 2 0.031
aromatic compound catabolic process GO:0019439 286 0.030
negative regulation of interleukin 13 production GO:0032696 2 0.030
negative regulation of protein modification process GO:0031400 163 0.030
b cell differentiation GO:0030183 78 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.029
purine containing compound metabolic process GO:0072521 311 0.029
cytoplasmic transport GO:0016482 234 0.029
immune response regulating signaling pathway GO:0002764 125 0.028
regulation of establishment of protein localization GO:0070201 181 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
carbohydrate derivative catabolic process GO:1901136 231 0.027
immune effector process GO:0002252 321 0.027
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.026
lymphocyte differentiation GO:0030098 242 0.026
response to peptide hormone GO:0043434 127 0.026
epithelial cell development GO:0002064 159 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of secretion GO:0051046 274 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.026
regulation of ion transport GO:0043269 215 0.025
cellular response to peptide GO:1901653 92 0.025
regulation of cytokine production GO:0001817 266 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
myelination GO:0042552 74 0.024
macromolecule glycosylation GO:0043413 55 0.024
muscle cell differentiation GO:0042692 261 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
production of molecular mediator of immune response GO:0002440 103 0.024
adaptive immune response GO:0002250 155 0.024
carbohydrate metabolic process GO:0005975 230 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.024
organonitrogen compound catabolic process GO:1901565 264 0.023
rhythmic process GO:0048511 174 0.023
entry into other organism involved in symbiotic interaction GO:0051828 15 0.023
anatomical structure homeostasis GO:0060249 145 0.023
lipid biosynthetic process GO:0008610 179 0.023
response to lipopolysaccharide GO:0032496 128 0.023
glycerolipid metabolic process GO:0046486 122 0.023
organophosphate catabolic process GO:0046434 232 0.023
neuronal action potential GO:0019228 54 0.023
rho protein signal transduction GO:0007266 32 0.023
regulation of protein localization GO:0032880 231 0.023
mitochondrion organization GO:0007005 134 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.023
immune response activating signal transduction GO:0002757 116 0.023
blood vessel morphogenesis GO:0048514 285 0.022
glycosylation GO:0070085 62 0.022
alcohol metabolic process GO:0006066 116 0.022
activation of immune response GO:0002253 138 0.022
negative regulation of molecular function GO:0044092 258 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
glycoprotein metabolic process GO:0009100 116 0.022
maintenance of location GO:0051235 89 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.021
b cell activation GO:0042113 161 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
cation transport GO:0006812 399 0.021
cell activation involved in immune response GO:0002263 126 0.021
ensheathment of neurons GO:0007272 76 0.021
protein maturation GO:0051604 176 0.021
leukocyte mediated immunity GO:0002443 174 0.021
action potential GO:0001508 78 0.021
regulation of t cell activation GO:0050863 170 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
peptidyl amino acid modification GO:0018193 336 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
myeloid cell homeostasis GO:0002262 114 0.021
neural precursor cell proliferation GO:0061351 121 0.020
cytokine production involved in immune response GO:0002367 34 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
muscle tissue development GO:0060537 308 0.020
cognition GO:0050890 149 0.020
transmission of nerve impulse GO:0019226 76 0.020
viral process GO:0016032 41 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
negative regulation of interleukin 5 secretion GO:2000663 1 0.020
heterocycle catabolic process GO:0046700 280 0.020
placenta development GO:0001890 140 0.020
glucose homeostasis GO:0042593 128 0.020
mapk cascade GO:0000165 281 0.020
blood circulation GO:0008015 195 0.020
regulation of interferon beta biosynthetic process GO:0045357 4 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
positive regulation of programmed cell death GO:0043068 218 0.019
positive regulation of organelle organization GO:0010638 128 0.019
positive regulation of cell development GO:0010720 237 0.019
regulation of system process GO:0044057 200 0.019
carbohydrate homeostasis GO:0033500 128 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
natural killer cell activation GO:0030101 44 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of lymphocyte differentiation GO:0045619 107 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
regulation of secretion by cell GO:1903530 249 0.019
regulation of leukocyte mediated immunity GO:0002703 104 0.019
organelle fission GO:0048285 170 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
ribonucleotide catabolic process GO:0009261 208 0.018
negative regulation of phagocytosis GO:0050765 4 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
mitotic cell cycle GO:0000278 195 0.018
sensory perception GO:0007600 245 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
learning or memory GO:0007611 148 0.018
lipopolysaccharide metabolic process GO:0008653 2 0.018
positive regulation of cell activation GO:0050867 158 0.018
response to insulin GO:0032868 100 0.018
protein catabolic process GO:0030163 221 0.018
regulation of multi organism process GO:0043900 111 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
leukocyte migration GO:0050900 124 0.018
dna metabolic process GO:0006259 303 0.017
negative regulation of immune effector process GO:0002698 55 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
t cell activation GO:0042110 289 0.017
regulation of cellular response to stress GO:0080135 159 0.017
defense response to other organism GO:0098542 197 0.017
extracellular matrix organization GO:0030198 147 0.017
sequestering of calcium ion GO:0051208 18 0.017
regulation of inflammatory response GO:0050727 147 0.017
regulation of cell cycle GO:0051726 281 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
organelle localization GO:0051640 179 0.017
synaptic transmission GO:0007268 329 0.017
embryonic placenta development GO:0001892 98 0.017
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
cytokine mediated signaling pathway GO:0019221 115 0.017
transmembrane transport GO:0055085 412 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.016
endomembrane system organization GO:0010256 147 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
cellular chemical homeostasis GO:0055082 215 0.016
negative regulation of b cell receptor signaling pathway GO:0050859 4 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
protein polymerization GO:0051258 57 0.016
regulation of cell projection organization GO:0031344 206 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
microtubule based process GO:0007017 236 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
nitrogen compound transport GO:0071705 271 0.016
positive regulation of secretion GO:0051047 130 0.016
nucleoside metabolic process GO:0009116 246 0.016
regionalization GO:0003002 337 0.016
protein oligomerization GO:0051259 67 0.016
cellular homeostasis GO:0019725 240 0.016
negative regulation of cell development GO:0010721 169 0.016
cellular response to biotic stimulus GO:0071216 92 0.015
entry into host cell GO:0030260 15 0.015
response to peptide GO:1901652 136 0.015
ras protein signal transduction GO:0007265 77 0.015
neural tube formation GO:0001841 108 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
axonogenesis GO:0007409 274 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
protein glycosylation GO:0006486 55 0.015
striated muscle tissue development GO:0014706 293 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
tissue homeostasis GO:0001894 115 0.015
positive regulation of cell migration GO:0030335 109 0.015
negative regulation of cytokine production GO:0001818 84 0.015
response to growth factor GO:0070848 198 0.015
viral gene expression GO:0019080 3 0.015
single fertilization GO:0007338 82 0.015
regulation of kinase activity GO:0043549 249 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
actin cytoskeleton organization GO:0030036 220 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
defense response to virus GO:0051607 68 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
mitotic cell cycle process GO:1903047 159 0.014
lymphocyte proliferation GO:0046651 164 0.014
cell type specific apoptotic process GO:0097285 268 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
axon ensheathment GO:0008366 76 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
camera type eye development GO:0043010 266 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
exocytosis GO:0006887 121 0.014
regulation of b cell activation GO:0050864 81 0.014
leukocyte proliferation GO:0070661 172 0.014
entry into host GO:0044409 15 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
cellular response to insulin stimulus GO:0032869 78 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
positive regulation of cytokine production GO:0001819 174 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
regulation of angiotensin levels in blood GO:0002002 4 0.014
male gamete generation GO:0048232 285 0.014
myotube differentiation GO:0014902 105 0.014
positive regulation of interleukin 18 production GO:0032741 2 0.014
ion transmembrane transport GO:0034220 361 0.014
positive regulation of vasoconstriction GO:0045907 4 0.014
positive regulation of cell death GO:0010942 224 0.014
asymmetric neuroblast division GO:0055059 1 0.014
protein ubiquitination GO:0016567 171 0.014
positive regulation of interferon alpha production GO:0032727 4 0.014
regulation of actin nucleation GO:0051125 4 0.014
viral life cycle GO:0019058 36 0.014
negative regulation of defense response GO:0031348 77 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.013
organic acid biosynthetic process GO:0016053 86 0.013
response to acid chemical GO:0001101 111 0.013
multicellular organism growth GO:0035264 161 0.013
regulation of transferase activity GO:0051338 263 0.013
forebrain development GO:0030900 302 0.013
calcium mediated signaling GO:0019722 46 0.013
spermatogenesis GO:0007283 284 0.013
t cell receptor signaling pathway GO:0050852 46 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
monosaccharide metabolic process GO:0005996 106 0.013
lateral inhibition GO:0046331 1 0.013
cation homeostasis GO:0055080 212 0.013
mitotic cytokinesis GO:0000281 4 0.013
interaction with host GO:0051701 22 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
steroid metabolic process GO:0008202 119 0.013
regulation of cell migration GO:0030334 219 0.013
wound healing GO:0042060 157 0.013
sensory perception of chemical stimulus GO:0007606 51 0.013
positive regulation of immune effector process GO:0002699 107 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
nucleotide catabolic process GO:0009166 217 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of anatomical structure size GO:0090066 178 0.013
cardiac muscle tissue development GO:0048738 130 0.013
heparin biosynthetic process GO:0030210 2 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
protein localization to organelle GO:0033365 185 0.012
cell division GO:0051301 120 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
fatty acid metabolic process GO:0006631 121 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
actin filament polymerization GO:0030041 44 0.012
regulation of cell motility GO:2000145 236 0.012
interspecies interaction between organisms GO:0044419 83 0.012
epithelial tube formation GO:0072175 130 0.012
cellular protein complex assembly GO:0043623 116 0.012
protein processing GO:0016485 163 0.012
asymmetric stem cell division GO:0098722 3 0.012
negative regulation of organelle organization GO:0010639 90 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
cellular response to external stimulus GO:0071496 88 0.012
microtubule based transport GO:0010970 50 0.012
regulation of tumor necrosis factor production GO:0032680 49 0.012
regulation of protein kinase activity GO:0045859 232 0.012
negative regulation of cell activation GO:0050866 111 0.012
sequestering of metal ion GO:0051238 19 0.012
methylation GO:0032259 134 0.012
photoreceptor cell development GO:0042461 40 0.012
regulation of ion homeostasis GO:2000021 64 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.012
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.012
b cell proliferation GO:0042100 53 0.012
humoral immune response GO:0006959 57 0.012
regulation of mapk cascade GO:0043408 248 0.012
purine containing compound catabolic process GO:0072523 213 0.011
pallium development GO:0021543 120 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
endocytosis GO:0006897 168 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
glial cell apoptotic process GO:0034349 3 0.011
regulation of hormone levels GO:0010817 211 0.011
dna repair GO:0006281 107 0.011
locomotory behavior GO:0007626 195 0.011
gonad development GO:0008406 141 0.011
innate immune response in mucosa GO:0002227 3 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
cellular ion homeostasis GO:0006873 165 0.011
compound eye development GO:0048749 1 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
neuron apoptotic process GO:0051402 142 0.011
negative regulation of multi organism process GO:0043901 68 0.011
cardiac chamber development GO:0003205 108 0.011
telencephalon development GO:0021537 186 0.011
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.011
regulation of eosinophil migration GO:2000416 2 0.011
negative regulation of growth GO:0045926 99 0.011
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
negative regulation of leukocyte mediated immunity GO:0002704 29 0.011
neuron death GO:0070997 154 0.011
establishment of organelle localization GO:0051656 122 0.011
cerebral cortex development GO:0021987 86 0.011
regulation of viral transcription GO:0046782 3 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of actin filament based process GO:0032970 99 0.011
nuclear division GO:0000280 158 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
actin filament organization GO:0007015 113 0.011
positive regulation of nervous system development GO:0051962 221 0.011
protein secretion GO:0009306 111 0.011
angiogenesis GO:0001525 201 0.011
multicellular organismal signaling GO:0035637 91 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
cell adhesion GO:0007155 329 0.011
regulation of acute inflammatory response GO:0002673 27 0.011
natural killer cell activation involved in immune response GO:0002323 10 0.011
nucleotide metabolic process GO:0009117 332 0.011
t cell differentiation GO:0030217 174 0.011
transepithelial chloride transport GO:0030321 4 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
response to inorganic substance GO:0010035 96 0.011
nucleoside catabolic process GO:0009164 206 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
response to light stimulus GO:0009416 135 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
regulation of neural retina development GO:0061074 3 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
glucose metabolic process GO:0006006 92 0.010
mitochondrion distribution GO:0048311 4 0.010
positive regulation of defense response GO:0031349 124 0.010
developmental maturation GO:0021700 193 0.010
cellular amide metabolic process GO:0043603 58 0.010
respiratory system development GO:0060541 190 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of protein processing GO:0070613 96 0.010
cellular protein catabolic process GO:0044257 155 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
respiratory tube development GO:0030323 167 0.010
negative regulation of leukocyte differentiation GO:1902106 51 0.010
regulation of interleukin 18 production GO:0032661 3 0.010
ribose phosphate metabolic process GO:0019693 291 0.010
second messenger mediated signaling GO:0019932 73 0.010
erythrocyte differentiation GO:0030218 88 0.010
regulation of protein oligomerization GO:0032459 4 0.010

G6pd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.015
disease of metabolism DOID:0014667 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
immune system disease DOID:2914 0 0.014
disease of anatomical entity DOID:7 0 0.014
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.012
hematopoietic system disease DOID:74 0 0.010