Mus musculus

12 known processes

Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

(Aliases: alpha-PIX,4930592P22Rik,1700038J06Rik,1600028C08Rik)

Arhgef6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of gtp catabolic process GO:0033126 85 0.367
Mouse
purine nucleotide catabolic process GO:0006195 211 0.350
Mouse
ras protein signal transduction GO:0007265 77 0.316
guanosine containing compound metabolic process GO:1901068 144 0.310
Mouse
nucleotide catabolic process GO:0009166 217 0.299
Mouse
purine nucleotide metabolic process GO:0006163 302 0.295
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.276
Mouse
glycosyl compound catabolic process GO:1901658 206 0.268
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.261
Mouse
regulation of gtp catabolic process GO:0033124 113 0.257
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.251
Mouse
ribonucleotide metabolic process GO:0009259 291 0.246
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.243
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.243
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.236
Mouse
ribonucleotide catabolic process GO:0009261 208 0.235
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.232
Mouse
glycosyl compound metabolic process GO:1901657 246 0.232
Mouse
purine containing compound catabolic process GO:0072523 213 0.229
Mouse
heterocycle catabolic process GO:0046700 280 0.218
Mouse
regulation of hydrolase activity GO:0051336 246 0.217
Mouse
gtp catabolic process GO:0006184 143 0.191
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.189
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.187
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.185
Mouse
rho protein signal transduction GO:0007266 32 0.183
g protein coupled receptor signaling pathway GO:0007186 243 0.177
positive regulation of nucleotide catabolic process GO:0030813 88 0.175
Mouse
nucleoside catabolic process GO:0009164 206 0.173
Mouse
purine containing compound metabolic process GO:0072521 311 0.171
Mouse
aromatic compound catabolic process GO:0019439 286 0.164
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.163
Mouse
nucleotide metabolic process GO:0009117 332 0.161
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.157
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.156
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.155
Mouse
positive regulation of gtpase activity GO:0043547 85 0.154
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.142
Mouse
ribose phosphate metabolic process GO:0019693 291 0.142
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.141
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.141
Mouse
purine nucleoside metabolic process GO:0042278 241 0.135
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.134
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.134
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.134
Mouse
gtp metabolic process GO:0046039 144 0.134
Mouse
regulation of rho gtpase activity GO:0032319 58 0.127
Mouse
purine nucleoside catabolic process GO:0006152 205 0.123
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.122
Mouse
ribonucleoside metabolic process GO:0009119 245 0.120
Mouse
regulation of ras gtpase activity GO:0032318 88 0.120
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.120
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.119
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.112
Mouse
ribonucleoside catabolic process GO:0042454 206 0.111
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.111
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.109
Mouse
regulation of cellular catabolic process GO:0031329 242 0.106
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.096
Mouse
regulation of nucleotide catabolic process GO:0030811 122 0.096
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.095
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.095
Mouse
nucleoside metabolic process GO:0009116 246 0.094
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.093
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.090
organophosphate catabolic process GO:0046434 232 0.090
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.081
cytoplasmic transport GO:0016482 234 0.074
gland development GO:0048732 330 0.074
mapk cascade GO:0000165 281 0.072
macromolecule catabolic process GO:0009057 281 0.070
cellular amino acid metabolic process GO:0006520 103 0.070
cation transport GO:0006812 399 0.064
intracellular protein transport GO:0006886 204 0.062
hematopoietic progenitor cell differentiation GO:0002244 143 0.060
Mouse
amine metabolic process GO:0009308 45 0.060
regulation of cellular amine metabolic process GO:0033238 20 0.059
immune effector process GO:0002252 321 0.057
cellular macromolecule catabolic process GO:0044265 206 0.055
negative regulation of molecular function GO:0044092 258 0.052
nuclear transport GO:0051169 139 0.051
cellular amine metabolic process GO:0044106 44 0.051
response to oxidative stress GO:0006979 123 0.049
cytokine production GO:0001816 319 0.048
transmembrane transport GO:0055085 412 0.048
immune response regulating signaling pathway GO:0002764 125 0.046
regulation of cell adhesion GO:0030155 154 0.044
t cell activation GO:0042110 289 0.044
ion transmembrane transport GO:0034220 361 0.044
protein catabolic process GO:0030163 221 0.043
regulation of ras protein signal transduction GO:0046578 114 0.043
Mouse
regulation of organelle organization GO:0033043 289 0.042
nucleocytoplasmic transport GO:0006913 139 0.041
protein localization to organelle GO:0033365 185 0.041
regulation of cytokine production GO:0001817 266 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
multicellular organismal response to stress GO:0033555 62 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
actin cytoskeleton organization GO:0030036 220 0.039
cell substrate adhesion GO:0031589 130 0.039
protein targeting GO:0006605 143 0.038
regulation of transferase activity GO:0051338 263 0.037
leukocyte proliferation GO:0070661 172 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.037
negative regulation of protein metabolic process GO:0051248 282 0.036
positive regulation of protein modification process GO:0031401 299 0.035
protein import GO:0017038 101 0.034
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.034
positive regulation of nucleotide metabolic process GO:0045981 114 0.034
Mouse
regulation of cell motility GO:2000145 236 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.033
chemotaxis GO:0006935 247 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
regulation of cell activation GO:0050865 289 0.032
cell adhesion GO:0007155 329 0.032
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.032
organelle localization GO:0051640 179 0.032
leukocyte differentiation GO:0002521 342 0.030
activation of immune response GO:0002253 138 0.030
positive regulation of apoptotic process GO:0043065 217 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
positive regulation of cell death GO:0010942 224 0.030
cation transmembrane transport GO:0098655 266 0.030
microtubule based process GO:0007017 236 0.029
dephosphorylation GO:0016311 129 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
regulation of rho protein signal transduction GO:0035023 71 0.029
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
regulation of protein localization GO:0032880 231 0.028
muscle cell differentiation GO:0042692 261 0.028
compound eye development GO:0048749 1 0.028
protein localization to nucleus GO:0034504 121 0.028
inorganic ion transmembrane transport GO:0098660 234 0.028
negative regulation of cellular component organization GO:0051129 194 0.027
regulation of mapk cascade GO:0043408 248 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
cellular ion homeostasis GO:0006873 165 0.027
positive regulation of mammary gland epithelial cell proliferation GO:0033601 5 0.027
regulation of cell substrate adhesion GO:0010810 73 0.027
regulation of cytoskeleton organization GO:0051493 122 0.027
leukocyte mediated immunity GO:0002443 174 0.026
blood circulation GO:0008015 195 0.026
blood vessel morphogenesis GO:0048514 285 0.026
divalent inorganic cation homeostasis GO:0072507 138 0.026
response to molecule of bacterial origin GO:0002237 143 0.026
fertilization GO:0009566 127 0.026
regulation of body fluid levels GO:0050878 162 0.026
regulation of neuron differentiation GO:0045664 281 0.026
immune response activating signal transduction GO:0002757 116 0.025
inflammatory response GO:0006954 244 0.025
divalent metal ion transport GO:0070838 172 0.025
positive regulation of mapk cascade GO:0043410 170 0.025
apoptotic signaling pathway GO:0097190 306 0.024
divalent inorganic cation transport GO:0072511 178 0.024
response to organonitrogen compound GO:0010243 246 0.024
regulation of t cell activation GO:0050863 170 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
response to lipopolysaccharide GO:0032496 128 0.024
membrane organization GO:0061024 245 0.024
carbohydrate metabolic process GO:0005975 230 0.024
regulation of protein transport GO:0051223 163 0.024
positive regulation of cell adhesion GO:0045785 80 0.024
negative regulation of phosphorylation GO:0042326 166 0.023
peptidyl amino acid modification GO:0018193 336 0.023
synaptic transmission GO:0007268 329 0.023
Fly
inorganic cation transmembrane transport GO:0098662 207 0.023
cellular response to oxidative stress GO:0034599 76 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
regulation of cell migration GO:0030334 219 0.023
lymphocyte proliferation GO:0046651 164 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
modification dependent macromolecule catabolic process GO:0043632 133 0.023
camera type eye development GO:0043010 266 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
protein ubiquitination GO:0016567 171 0.022
ameboidal type cell migration GO:0001667 128 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
regulation of actin filament based process GO:0032970 99 0.022
skeletal system development GO:0001501 356 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
cell matrix adhesion GO:0007160 68 0.022
regulation of actin cytoskeleton organization GO:0032956 84 0.022
regulation of secretion by cell GO:1903530 249 0.021
regulation of anatomical structure size GO:0090066 178 0.021
regulation of leukocyte proliferation GO:0070663 121 0.021
muscle tissue development GO:0060537 308 0.021
single organism nuclear import GO:1902593 95 0.021
maintenance of location GO:0051235 89 0.021
t cell proliferation GO:0042098 120 0.021
positive regulation of nervous system development GO:0051962 221 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
cell junction organization GO:0034330 77 0.021
organelle assembly GO:0070925 177 0.021
cellular protein complex assembly GO:0043623 116 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
digestive tract development GO:0048565 190 0.021
axonogenesis GO:0007409 274 0.021
calcium ion homeostasis GO:0055074 127 0.021
negative regulation of immune system process GO:0002683 209 0.021
epithelial cell proliferation GO:0050673 174 0.021
regulation of membrane potential GO:0042391 192 0.020
cellular chemical homeostasis GO:0055082 215 0.020
circulatory system process GO:0003013 197 0.020
learning or memory GO:0007611 148 0.020
cellular ketone metabolic process GO:0042180 84 0.020
calcium ion transport GO:0006816 159 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
positive regulation of organelle organization GO:0010638 128 0.020
response to pain GO:0048265 26 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
mitotic cell cycle GO:0000278 195 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
regulation of protein kinase activity GO:0045859 232 0.019
striated muscle tissue development GO:0014706 293 0.019
skeletal muscle organ development GO:0060538 163 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
multicellular organismal signaling GO:0035637 91 0.019
regulation of jak stat cascade GO:0046425 34 0.019
homeostasis of number of cells GO:0048872 210 0.019
b cell activation GO:0042113 161 0.019
regulation of cell projection organization GO:0031344 206 0.019
positive regulation of epithelial cell proliferation GO:0050679 68 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
mitochondrion organization GO:0007005 134 0.019
renal system development GO:0072001 225 0.019
cellular protein catabolic process GO:0044257 155 0.019
nuclear import GO:0051170 95 0.019
positive regulation of cell migration GO:0030335 109 0.019
metal ion homeostasis GO:0055065 189 0.019
regulation of defense response GO:0031347 233 0.019
cation homeostasis GO:0055080 212 0.018
protein processing GO:0016485 163 0.018
protein import into nucleus GO:0006606 95 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
negative regulation of cell activation GO:0050866 111 0.018
nucleoside monophosphate metabolic process GO:0009123 85 0.018
nuclear division GO:0000280 158 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
muscle system process GO:0003012 141 0.018
multicellular organism growth GO:0035264 161 0.018
regulation of cell cycle GO:0051726 281 0.018
mitotic cell cycle process GO:1903047 159 0.018
endocytosis GO:0006897 168 0.018
endomembrane system organization GO:0010256 147 0.018
cognition GO:0050890 149 0.018
regulation of ion transport GO:0043269 215 0.018
cellular homeostasis GO:0019725 240 0.018
positive regulation of rac gtpase activity GO:0032855 14 0.018
Mouse
positive regulation of cell development GO:0010720 237 0.018
organelle fission GO:0048285 170 0.018
oxidation reduction process GO:0055114 342 0.018
positive regulation of cytokine production GO:0001819 174 0.018
single fertilization GO:0007338 82 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of secretion GO:0051046 274 0.017
rap protein signal transduction GO:0032486 3 0.017
sequestering of calcium ion GO:0051208 18 0.017
cell division GO:0051301 120 0.017
wound healing GO:0042060 157 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
forebrain development GO:0030900 302 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
regulation of transmembrane transport GO:0034762 128 0.017
anatomical structure homeostasis GO:0060249 145 0.017
protein maturation GO:0051604 176 0.017
fat cell differentiation GO:0045444 160 0.017
digestive system development GO:0055123 200 0.017
regulation of kinase activity GO:0043549 249 0.016
glycoprotein metabolic process GO:0009100 116 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
anion transport GO:0006820 177 0.016
peptidyl serine modification GO:0018209 83 0.016
urogenital system development GO:0001655 261 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
heart contraction GO:0060047 93 0.016
positive regulation of rho gtpase activity GO:0032321 41 0.016
Mouse
regulation of system process GO:0044057 200 0.016
response to inorganic substance GO:0010035 96 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
muscle cell development GO:0055001 133 0.015
proteasomal protein catabolic process GO:0010498 98 0.015
heart process GO:0003015 94 0.015
cell growth GO:0016049 130 0.015
lamellipodium organization GO:0097581 29 0.015
positive regulation of cell substrate adhesion GO:0010811 47 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
cellular response to lipid GO:0071396 145 0.015
exocytosis GO:0006887 121 0.015
adaptive immune response GO:0002250 155 0.015
nitrogen compound transport GO:0071705 271 0.015
regulation of proteolysis GO:0030162 164 0.015
response to transforming growth factor beta GO:0071559 88 0.015
axon guidance GO:0007411 141 0.015
transmission of nerve impulse GO:0019226 76 0.015
synapse organization GO:0050808 125 0.015
Fly
regulation of t cell proliferation GO:0042129 92 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
production of molecular mediator of immune response GO:0002440 103 0.015
cellular divalent inorganic cation homeostasis GO:0072503 127 0.015
regulation of response to wounding GO:1903034 189 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
negative regulation of protein maturation GO:1903318 79 0.015
response to organic cyclic compound GO:0014070 198 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.015
cell type specific apoptotic process GO:0097285 268 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.014
muscle contraction GO:0006936 101 0.014
response to growth factor GO:0070848 198 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
striated muscle myosin thick filament assembly GO:0071688 1 0.014
organic anion transport GO:0015711 137 0.014
regulation of muscle system process GO:0090257 80 0.014
innate immune response GO:0045087 157 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
cell recognition GO:0008037 83 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
stem cell differentiation GO:0048863 268 0.014
dna metabolic process GO:0006259 303 0.014
protein polymerization GO:0051258 57 0.014
lymphocyte differentiation GO:0030098 242 0.014
striated muscle cell development GO:0055002 125 0.014
mitochondrion distribution GO:0048311 4 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
heart morphogenesis GO:0003007 178 0.014
single organism cell adhesion GO:0098602 156 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
positive regulation of cell activation GO:0050867 158 0.014
kidney development GO:0001822 213 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
cell activation involved in immune response GO:0002263 126 0.014
negative regulation of organelle organization GO:0010639 90 0.014
positive regulation of cell motility GO:2000147 116 0.014
response to peptide hormone GO:0043434 127 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
myosin filament assembly GO:0031034 2 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
negative regulation of cell development GO:0010721 169 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
regulation of neuron death GO:1901214 134 0.013
spermatogenesis GO:0007283 284 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
negative regulation of protein processing GO:0010955 79 0.013
cell cell junction organization GO:0045216 72 0.013
actin filament polymerization GO:0030041 44 0.013
digestive tract morphogenesis GO:0048546 147 0.013
negative regulation of hydrolase activity GO:0051346 71 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
actin filament organization GO:0007015 113 0.013
cytokinetic process GO:0032506 2 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of b cell activation GO:0050864 81 0.013
tissue remodeling GO:0048771 102 0.013
coagulation GO:0050817 78 0.013
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.013
fibroblast migration GO:0010761 21 0.013
plasma membrane organization GO:0007009 90 0.013
antigen receptor mediated signaling pathway GO:0050851 64 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
regulation of cellular component size GO:0032535 121 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
action potential GO:0001508 78 0.012
positive regulation of immune effector process GO:0002699 107 0.012
blood coagulation GO:0007596 76 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
sensory perception GO:0007600 245 0.012
carbohydrate homeostasis GO:0033500 128 0.012
lateral inhibition GO:0046331 1 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of blood circulation GO:1903522 93 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
placenta development GO:0001890 140 0.012
establishment of organelle localization GO:0051656 122 0.012
ossification GO:0001503 216 0.012
hemostasis GO:0007599 78 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
alpha beta t cell activation GO:0046631 91 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
membrane depolarization GO:0051899 64 0.012
regionalization GO:0003002 337 0.012
angiogenesis GO:0001525 201 0.012
protein import into nucleus translocation GO:0000060 12 0.012
learning GO:0007612 98 0.012
protein glycosylation GO:0006486 55 0.012
lipid localization GO:0010876 126 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
positive regulation of growth GO:0045927 104 0.012
developmental maturation GO:0021700 193 0.012
respiratory system development GO:0060541 190 0.012
regulation of homeostatic process GO:0032844 182 0.012
extracellular structure organization GO:0043062 148 0.012
phospholipid metabolic process GO:0006644 87 0.012
response to extracellular stimulus GO:0009991 127 0.012
neuron migration GO:0001764 122 0.012
neuron death GO:0070997 154 0.012
vesicle localization GO:0051648 86 0.012
protein localization to plasma membrane GO:0072659 57 0.011
regulation of protein maturation GO:1903317 96 0.011
response to nutrient levels GO:0031667 109 0.011
sequestering of metal ion GO:0051238 19 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
adult behavior GO:0030534 135 0.011
cell cell recognition GO:0009988 44 0.011
protein autophosphorylation GO:0046777 61 0.011
sensory organ morphogenesis GO:0090596 242 0.011
sodium ion transport GO:0006814 73 0.011
methylation GO:0032259 134 0.011
stem cell development GO:0048864 219 0.011
lipid biosynthetic process GO:0008610 179 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
regulation of actin nucleation GO:0051125 4 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
negative regulation of t cell activation GO:0050868 65 0.011
striated muscle contraction GO:0006941 45 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
gliogenesis GO:0042063 141 0.011
defense response to virus GO:0051607 68 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
regulation of metal ion transport GO:0010959 106 0.011
interleukin 8 production GO:0032637 4 0.011
positive regulation of ion transport GO:0043270 65 0.011
myeloid cell differentiation GO:0030099 233 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
myosin filament organization GO:0031033 3 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cardiac muscle tissue development GO:0048738 130 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
t cell differentiation GO:0030217 174 0.010
wnt signaling pathway GO:0016055 188 0.010
response to peptide GO:1901652 136 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
regulation of map kinase activity GO:0043405 120 0.010
mitotic cytokinesis GO:0000281 4 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
mrna metabolic process GO:0016071 84 0.010
establishment of vesicle localization GO:0051650 81 0.010
positive regulation of transferase activity GO:0051347 167 0.010
actin filament based movement GO:0030048 23 0.010
regulation of protein catabolic process GO:0042176 108 0.010
midgut development GO:0007494 4 0.010
regulation of multi organism process GO:0043900 111 0.010
negative regulation of neuron death GO:1901215 98 0.010
locomotory behavior GO:0007626 195 0.010
regulation of cell cycle process GO:0010564 160 0.010
lipid transport GO:0006869 98 0.010
chromatin modification GO:0016568 187 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
calcium ion transmembrane transport GO:0070588 85 0.010
positive regulation of secretion GO:0051047 130 0.010
regulation of leukocyte apoptotic process GO:2000106 56 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.010
b cell differentiation GO:0030183 78 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
neuron apoptotic process GO:0051402 142 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010

Arhgef6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.017
musculoskeletal system disease DOID:17 0 0.014
inherited metabolic disorder DOID:655 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
neurodegenerative disease DOID:1289 0 0.011