IMP

Process View

Mus musculus

12 genes annotated in mouse

protein import into nucleus translocation

A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein import into nucleus translocation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein import into nucleus translocation" (in gray)

Name	Description	Probability	Func Analog Organism
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.986
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.966
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.958
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.938
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.748
Trp53	transformation related protein 53	0.597
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.556	Rat
Eya1	eyes absent 1 homolog (Drosophila)	0.518
Pten	phosphatase and tensin homolog	0.457
Tnf	tumor necrosis factor	0.382
Ahr	aryl-hydrocarbon receptor	0.369
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.359
Clock	circadian locomotor output cycles kaput	0.266
Lyz2	lysozyme 2	0.259
Stat3	signal transducer and activator of transcription 3	0.218
Csf1	colony stimulating factor 1 (macrophage)	0.190
Spna1	spectrin alpha 1	0.184
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.159
Sim1	single-minded homolog 1 (Drosophila)	0.142
Myd88	myeloid differentiation primary response gene 88	0.138
Pbx1	pre B-cell leukemia transcription factor 1	0.136	Fly
Iqcb1	IQ calmodulin-binding motif containing 1	0.110
Per2	period homolog 2 (Drosophila)	0.104
Gck	glucokinase	0.093
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.065
Cry1	cryptochrome 1 (photolyase-like)	0.064
Stat5a	signal transducer and activator of transcription 5A	0.061
Mdm2	transformed mouse 3T3 cell double minute 2	0.060
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.060
Nphp1	nephronophthisis 1 (juvenile) homolog (human)	0.053
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.050	Rat
Rpgrip1l	Rpgrip1-like	0.050
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.049	Mouse
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.048	Rat
Fgfr1	fibroblast growth factor receptor 1	0.045
Ank1	ankyrin 1, erythroid	0.040
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.040
Fas	Fas (TNF receptor superfamily member 6)	0.040
Kit	kit oncogene	0.039
Cry2	cryptochrome 2 (photolyase-like)	0.038
Cdk2	cyclin-dependent kinase 2	0.038
Rag1	recombination activating gene 1	0.036
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.035
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.035	Mouse
Rb1	retinoblastoma 1	0.035
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.035
Fgfr2	fibroblast growth factor receptor 2	0.033
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.032	Mouse
Socs1	suppressor of cytokine signaling 1	0.032
Lepr	leptin receptor	0.031
Meis1	Meis homeobox 1	0.030
Tnip1	TNFAIP3 interacting protein 1	0.029
Insr	insulin receptor	0.027
Akt1	thymoma viral proto-oncogene 1	0.026	Human
Emx2	empty spiracles homolog 2 (Drosophila)	0.026
Ahi1	Abelson helper integration site 1	0.026
Hbb-b1	hemoglobin, beta adult major chain	0.026
Exoc6	exocyst complex component 6	0.025
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.025	Human
Hes5	hairy and enhancer of split 5 (Drosophila)	0.024
Hspa5	heat shock protein 5	0.024
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.024
Srf	serum response factor	0.023
Tfrc	transferrin receptor	0.023
Sox2	SRY-box containing gene 2	0.022
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.022
Pax3	paired box gene 3	0.022
Fgf3	fibroblast growth factor 3	0.021
Ikbkg	inhibitor of kappaB kinase gamma	0.021
Csnk1e	casein kinase 1, epsilon	0.020
Prdx1	peroxiredoxin 1	0.020
Hsph1	heat shock 105kDa/110kDa protein 1	0.020
Unc93b1	unc-93 homolog B1 (C. elegans)	0.020
Trp73	transformation related protein 73	0.020	Mouse
Spnb1	spectrin beta 1	0.020
Mdm4	transformed mouse 3T3 cell double minute 4	0.020
Prlr	prolactin receptor	0.019
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.019
C1qc	complement component 1, q subcomponent, C chain	0.019
Npas2	neuronal PAS domain protein 2	0.019
Apc	adenomatosis polyposis coli	0.018
Epb4.1	erythrocyte protein band 4.1	0.018
Vdr	vitamin D receptor	0.018
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.018
Igh	immunoglobulin heavy chain complex	0.018
Grip1	glutamate receptor interacting protein 1	0.018	Fly
Fbrs	fibrosin	0.018
Csnk1g2	casein kinase 1, gamma 2	0.018
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.017
Otp	orthopedia homolog (Drosophila)	0.017
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.017
Runx1	runt related transcription factor 1	0.017
Traf3	TNF receptor-associated factor 3	0.016
Timp1	tissue inhibitor of metalloproteinase 1	0.015
Braf	Braf transforming gene	0.015
Cct6a	chaperonin containing Tcp1, subunit 6a (zeta)	0.015
Bcl3	B-cell leukemia/lymphoma 3	0.015	Human Mouse
Dlx1	distal-less homeobox 1	0.015
Prrx2	paired related homeobox 2	0.015
Per1	period homolog 1 (Drosophila)	0.015
Ltbr	lymphotoxin B receptor	0.015
Hsf1	heat shock factor 1	0.015
Stat5b	signal transducer and activator of transcription 5B	0.015
Prkcd	protein kinase C, delta	0.014
Dach1	dachshund 1 (Drosophila)	0.014
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.014
Hes1	hairy and enhancer of split 1 (Drosophila)	0.014
Nog	noggin	0.014
Hnrnpf	heterogeneous nuclear ribonucleoprotein F	0.014
Fras1	Fraser syndrome 1 homolog (human)	0.014
Pola1	polymerase (DNA directed), alpha 1	0.014
Nf1	neurofibromatosis 1	0.014
Ifng	interferon gamma	0.014
Bcl2	B-cell leukemia/lymphoma 2	0.013
Emx1	empty spiracles homolog 1 (Drosophila)	0.013
Arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.012
Prrx1	paired related homeobox 1	0.012
Col1a1	collagen, type I, alpha 1	0.012
Pygo2	pygopus 2	0.012
Cic	capicua homolog (Drosophila)	0.011
Sim2	single-minded homolog 2 (Drosophila)	0.011
Hoxa9	homeobox A9	0.011
Rhog	ras homolog gene family, member G	0.011
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.011
Rnf19b	ring finger protein 19B	0.011
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.011
Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.011
Pparg	peroxisome proliferator activated receptor gamma	0.011
Mapkapk2	MAP kinase-activated protein kinase 2	0.011
Wnt3a	wingless-related MMTV integration site 3A	0.011
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.011
Foxi3	forkhead box I3	0.011
Tert	telomerase reverse transcriptase	0.011
Aes	amino-terminal enhancer of split	0.010
Yap1	yes-associated protein 1	0.010
Ccnd1	cyclin D1	0.010
Actg1	actin, gamma, cytoplasmic 1	0.010