Mus musculus

31 known processes

C4b

complement component 4B (Childo blood group)

(Aliases: Ss,C4)

C4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein activation cascade GO:0072376 19 0.828
complement activation GO:0006956 16 0.805
sterol metabolic process GO:0016125 58 0.449
cholesterol metabolic process GO:0008203 56 0.379
negative regulation of molecular function GO:0044092 258 0.288
Mouse
activation of immune response GO:0002253 138 0.287
regulation of defense response GO:0031347 233 0.272
Mouse
immune effector process GO:0002252 321 0.265
oxidation reduction process GO:0055114 342 0.234
negative regulation of protein metabolic process GO:0051248 282 0.218
Mouse
neutral lipid metabolic process GO:0006638 57 0.196
humoral immune response GO:0006959 57 0.189
innate immune response GO:0045087 157 0.185
positive regulation of protein phosphorylation GO:0001934 242 0.183
negative regulation of immune system process GO:0002683 209 0.173
lymphocyte mediated immunity GO:0002449 139 0.167
angiogenesis GO:0001525 201 0.161
Mouse
cell adhesion GO:0007155 329 0.158
carbohydrate metabolic process GO:0005975 230 0.146
regulation of inflammatory response GO:0050727 147 0.145
Mouse
regulation of protein kinase activity GO:0045859 232 0.145
cellular amino acid metabolic process GO:0006520 103 0.141
cellular lipid metabolic process GO:0044255 323 0.133
regulation of protein processing GO:0070613 96 0.131
Mouse
regulation of peptidase activity GO:0052547 96 0.127
Mouse
fatty acid metabolic process GO:0006631 121 0.125
regulation of cytokine production GO:0001817 266 0.121
regulation of cellular ketone metabolic process GO:0010565 66 0.119
negative regulation of cellular protein metabolic process GO:0032269 247 0.118
Mouse
hexose biosynthetic process GO:0019319 39 0.118
negative regulation of hydrolase activity GO:0051346 71 0.118
Mouse
triglyceride metabolic process GO:0006641 51 0.118
cytokine production GO:0001816 319 0.112
cellular amine metabolic process GO:0044106 44 0.111
immunoglobulin mediated immune response GO:0016064 69 0.110
cellular ketone metabolic process GO:0042180 84 0.110
protein processing GO:0016485 163 0.109
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.107
regulation of kinase activity GO:0043549 249 0.105
spermatogenesis GO:0007283 284 0.103
positive regulation of protein modification process GO:0031401 299 0.103
response to lipopolysaccharide GO:0032496 128 0.103
cellular response to cytokine stimulus GO:0071345 189 0.102
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.100
regulation of vasculature development GO:1901342 88 0.098
Mouse
male gamete generation GO:0048232 285 0.096
activation of nf kappab inducing kinase activity GO:0007250 4 0.094
macromolecule glycosylation GO:0043413 55 0.094
complement activation lectin pathway GO:0001867 5 0.093
regulation of proteolysis GO:0030162 164 0.092
Mouse
regulation of response to wounding GO:1903034 189 0.092
Mouse
acylglycerol metabolic process GO:0006639 55 0.092
response to peptide hormone GO:0043434 127 0.092
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.090
response to molecule of bacterial origin GO:0002237 143 0.090
glycerolipid metabolic process GO:0046486 122 0.089
protein maturation GO:0051604 176 0.088
Mouse
inflammatory response GO:0006954 244 0.085
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.083
negative regulation of cell proliferation GO:0008285 296 0.083
positive regulation of kinase activity GO:0033674 155 0.083
amine metabolic process GO:0009308 45 0.082
monocarboxylic acid metabolic process GO:0032787 191 0.082
positive regulation of cytokine production GO:0001819 174 0.081
positive regulation of protein kinase c activity GO:1900020 1 0.080
carboxylic acid biosynthetic process GO:0046394 86 0.080
regulation of cholesterol metabolic process GO:0090181 14 0.079
fatty acid biosynthetic process GO:0006633 41 0.079
regulation of cellular amino acid metabolic process GO:0006521 5 0.079
negative regulation of endopeptidase activity GO:0010951 44 0.079
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.075
positive regulation of protein kinase activity GO:0045860 144 0.073
positive regulation of apoptotic process GO:0043065 217 0.071
fat cell differentiation GO:0045444 160 0.071
response to interferon gamma GO:0034341 34 0.070
regulation of gluconeogenesis GO:0006111 30 0.069
regulation of acute inflammatory response GO:0002673 27 0.069
Mouse
regulation of endopeptidase activity GO:0052548 89 0.068
Mouse
hexose metabolic process GO:0019318 98 0.067
response to peptide GO:1901652 136 0.067
reactive nitrogen species metabolic process GO:2001057 0 0.065
circulatory system process GO:0003013 197 0.065
mapk cascade GO:0000165 281 0.065
organic hydroxy compound metabolic process GO:1901615 203 0.063
b cell mediated immunity GO:0019724 71 0.063
adaptive immune response GO:0002250 155 0.062
acute inflammatory response GO:0002526 41 0.062
Mouse
regulation of hydrolase activity GO:0051336 246 0.061
Mouse
reactive oxygen species biosynthetic process GO:1903409 8 0.060
monosaccharide metabolic process GO:0005996 106 0.059
regulation of protein kinase c activity GO:1900019 1 0.059
positive regulation of transferase activity GO:0051347 167 0.059
monosaccharide biosynthetic process GO:0046364 44 0.056
peptidyl amino acid modification GO:0018193 336 0.055
regulation of transferase activity GO:0051338 263 0.054
response to organonitrogen compound GO:0010243 246 0.054
blood vessel morphogenesis GO:0048514 285 0.053
Mouse
aromatic compound catabolic process GO:0019439 286 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.052
regulation of hormone levels GO:0010817 211 0.051
response to insulin GO:0032868 100 0.051
negative regulation of protein processing GO:0010955 79 0.051
Mouse
urogenital system development GO:0001655 261 0.051
regulation of adaptive immune response GO:0002819 90 0.051
Mouse
cellular response to interferon gamma GO:0071346 25 0.050
carbohydrate biosynthetic process GO:0016051 74 0.050
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.050
regulation of glucose metabolic process GO:0010906 60 0.050
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.050
Mouse
leukocyte mediated immunity GO:0002443 174 0.050
astrocyte activation GO:0048143 2 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
regulation of epithelial cell proliferation GO:0050678 141 0.049
alcohol metabolic process GO:0006066 116 0.048
cellular response to organonitrogen compound GO:0071417 145 0.048
positive regulation of cell death GO:0010942 224 0.046
protein glycosylation GO:0006486 55 0.044
defense response to other organism GO:0098542 197 0.044
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.043
kidney epithelium development GO:0072073 121 0.043
regulation of cell activation GO:0050865 289 0.042
gliogenesis GO:0042063 141 0.042
positive regulation of angiogenesis GO:0045766 46 0.042
Mouse
negative regulation of complement activation GO:0045916 3 0.041
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.041
organonitrogen compound catabolic process GO:1901565 264 0.041
regulation of lipid metabolic process GO:0019216 118 0.040
positive regulation of fatty acid metabolic process GO:0045923 8 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
epithelial cell proliferation GO:0050673 174 0.040
regulation of fatty acid metabolic process GO:0019217 28 0.039
regulation of mapk cascade GO:0043408 248 0.039
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
small molecule biosynthetic process GO:0044283 132 0.039
positive regulation of mapk cascade GO:0043410 170 0.038
positive regulation of protein kinase b signaling GO:0051897 32 0.038
regulation of secretion GO:0051046 274 0.038
neuron death GO:0070997 154 0.038
organic acid biosynthetic process GO:0016053 86 0.038
production of molecular mediator of immune response GO:0002440 103 0.037
regulation of triglyceride metabolic process GO:0090207 17 0.037
negative regulation of gluconeogenesis GO:0045721 9 0.037
negative regulation of proteolysis GO:0045861 74 0.036
Mouse
lipid biosynthetic process GO:0008610 179 0.036
cellular response to insulin stimulus GO:0032869 78 0.035
muscle system process GO:0003012 141 0.035
epithelial cell development GO:0002064 159 0.035
positive regulation of cytokine secretion GO:0050715 41 0.035
gluconeogenesis GO:0006094 39 0.035
carbohydrate derivative biosynthetic process GO:1901137 183 0.035
glycoprotein biosynthetic process GO:0009101 89 0.034
positive regulation of activation of membrane attack complex GO:0001970 2 0.034
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.034
regulation of cell migration GO:0030334 219 0.034
regulation of neuron apoptotic process GO:0043523 122 0.034
regulation of angiogenesis GO:0045765 81 0.033
Mouse
transmembrane transport GO:0055085 412 0.033
regulation of carbohydrate metabolic process GO:0006109 75 0.032
cellular response to peptide GO:1901653 92 0.032
negative regulation of peptidase activity GO:0010466 46 0.032
Mouse
regulation of cellular catabolic process GO:0031329 242 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
regulation of renal output by angiotensin GO:0002019 2 0.031
monocarboxylic acid biosynthetic process GO:0072330 61 0.031
nucleotide metabolic process GO:0009117 332 0.031
steroid metabolic process GO:0008202 119 0.031
homeostasis of number of cells GO:0048872 210 0.031
glycoprotein metabolic process GO:0009100 116 0.031
multicellular organism growth GO:0035264 161 0.030
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.030
cell type specific apoptotic process GO:0097285 268 0.030
cellular response to peptide hormone stimulus GO:0071375 92 0.030
defense response to bacterium GO:0042742 119 0.030
ion transmembrane transport GO:0034220 361 0.030
gland development GO:0048732 330 0.030
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
epithelial tube morphogenesis GO:0060562 303 0.029
cation transport GO:0006812 399 0.029
protein localization to organelle GO:0033365 185 0.029
regulation of complement activation GO:0030449 7 0.029
Mouse
regulation of anatomical structure size GO:0090066 178 0.029
blood circulation GO:0008015 195 0.029
glial cell differentiation GO:0010001 131 0.029
regulation of carbohydrate biosynthetic process GO:0043255 40 0.028
regulation of secretion by cell GO:1903530 249 0.028
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.028
Mouse
negative regulation of lipid metabolic process GO:0045833 30 0.028
negative regulation of neuron apoptotic process GO:0043524 92 0.028
transition metal ion transport GO:0000041 38 0.028
cellular homeostasis GO:0019725 240 0.028
kidney development GO:0001822 213 0.028
glycosylation GO:0070085 62 0.027
organic acid catabolic process GO:0016054 51 0.027
purine containing compound metabolic process GO:0072521 311 0.027
regulation of protein secretion GO:0050708 82 0.027
response to steroid hormone GO:0048545 56 0.027
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.027
glucose metabolic process GO:0006006 92 0.026
positive regulation of nervous system development GO:0051962 221 0.026
immunoglobulin production GO:0002377 73 0.026
negative regulation of leukocyte differentiation GO:1902106 51 0.026
insulin receptor signaling pathway GO:0008286 49 0.026
cellular response to lipid GO:0071396 145 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
cytokine production involved in immune response GO:0002367 34 0.025
regulation of blood pressure GO:0008217 93 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
cell substrate adhesion GO:0031589 130 0.025
establishment of blood nerve barrier GO:0008065 3 0.025
female sex differentiation GO:0046660 84 0.025
regulation of protein maturation GO:1903317 96 0.024
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.024
protein n linked glycosylation GO:0006487 12 0.024
leukocyte activation involved in immune response GO:0002366 126 0.024
positive regulation of immune effector process GO:0002699 107 0.023
Mouse
neuron apoptotic process GO:0051402 142 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
response to acid chemical GO:0001101 111 0.023
extracellular structure organization GO:0043062 148 0.023
regulation of lymphocyte differentiation GO:0045619 107 0.023
regulation of insulin receptor signaling pathway GO:0046626 21 0.023
cellular macromolecule catabolic process GO:0044265 206 0.022
muscle tissue development GO:0060537 308 0.022
renal system process GO:0003014 48 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
negative regulation of cell activation GO:0050866 111 0.022
vascular process in circulatory system GO:0003018 62 0.022
regulation of macrophage activation GO:0043030 17 0.022
positive regulation of behavior GO:0048520 40 0.022
cellular chemical homeostasis GO:0055082 215 0.022
regulation of fatty acid biosynthetic process GO:0042304 12 0.022
positive regulation of tumor necrosis factor production GO:0032760 30 0.022
morphogenesis of a branching epithelium GO:0061138 193 0.022
positive regulation of endocytosis GO:0045807 42 0.021
Mouse
metanephric glomerular visceral epithelial cell development GO:0072249 2 0.021
carbohydrate homeostasis GO:0033500 128 0.021
endocrine process GO:0050886 39 0.021
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.021
positive regulation of protein transport GO:0051222 93 0.021
macromolecule catabolic process GO:0009057 281 0.020
chemotaxis GO:0006935 247 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
striated muscle tissue development GO:0014706 293 0.020
amide transport GO:0042886 138 0.020
macrophage activation GO:0042116 27 0.020
acylglycerol biosynthetic process GO:0046463 18 0.020
negative regulation of immune effector process GO:0002698 55 0.020
nitrogen compound transport GO:0071705 271 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
glucose homeostasis GO:0042593 128 0.019
response to radiation GO:0009314 165 0.019
negative regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000584 2 0.019
regulation of phospholipase a2 activity GO:0032429 3 0.019
small molecule catabolic process GO:0044282 71 0.019
negative regulation of protein maturation GO:1903318 79 0.019
Mouse
carboxylic acid catabolic process GO:0046395 51 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
cytokine secretion GO:0050663 72 0.019
negative regulation of defense response GO:0031348 77 0.019
positive regulation of cell development GO:0010720 237 0.019
heterocycle catabolic process GO:0046700 280 0.019
cellular response to monosaccharide stimulus GO:0071326 47 0.018
response to oxidative stress GO:0006979 123 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
nephron development GO:0072006 109 0.018
regulation of tube size GO:0035150 57 0.018
regulation of cellular response to stress GO:0080135 159 0.018
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.018
cell activation involved in immune response GO:0002263 126 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
hindbrain development GO:0030902 128 0.017
metanephric glomerular epithelial cell development GO:0072313 2 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
eosinophil migration GO:0072677 3 0.017
positive regulation of adaptive immune response GO:0002821 61 0.017
Mouse
ras protein signal transduction GO:0007265 77 0.017
leukocyte differentiation GO:0002521 342 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
response to monosaccharide GO:0034284 67 0.017
adiponectin secretion GO:0070162 2 0.017
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.017
regulation of cellular component biogenesis GO:0044087 181 0.017
positive regulation of eosinophil migration GO:2000418 2 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
brown fat cell differentiation GO:0050873 36 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of blood vessel size GO:0050880 56 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.017
negative regulation of epithelial cell proliferation GO:0050680 64 0.016
regulation of membrane potential GO:0042391 192 0.016
multicellular organismal signaling GO:0035637 91 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
nucleoside catabolic process GO:0009164 206 0.016
cation homeostasis GO:0055080 212 0.016
thymocyte migration GO:0072679 2 0.016
intracellular protein transport GO:0006886 204 0.016
nephron epithelium development GO:0072009 92 0.016
protein secretion GO:0009306 111 0.016
regulation of ossification GO:0030278 112 0.016
germ cell development GO:0007281 185 0.016
interleukin 8 production GO:0032637 4 0.016
positive regulation of leukocyte mediated immunity GO:0002705 70 0.016
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.016
nuclear transport GO:0051169 139 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
myeloid leukocyte activation GO:0002274 83 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
t cell differentiation GO:0030217 174 0.016
apoptotic signaling pathway GO:0097190 306 0.016
response to organic cyclic compound GO:0014070 198 0.016
regulation of lipid biosynthetic process GO:0046890 54 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.015
positive regulation of glucose transport GO:0010828 16 0.015
regulation of natural killer cell chemotaxis GO:2000501 1 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
positive regulation of cell activation GO:0050867 158 0.015
protein import GO:0017038 101 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
regulation of humoral immune response GO:0002920 22 0.015
Mouse
monosaccharide transport GO:0015749 58 0.015
cell cell adhesion GO:0098609 41 0.015
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.015
Mouse
muscle contraction GO:0006936 101 0.015
cellular protein catabolic process GO:0044257 155 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
dna metabolic process GO:0006259 303 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
intracellular cholesterol transport GO:0032367 3 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
nucleocytoplasmic transport GO:0006913 139 0.014
nucleoside metabolic process GO:0009116 246 0.014
spermatid differentiation GO:0048515 115 0.014
cytoplasmic transport GO:0016482 234 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
renal system development GO:0072001 225 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.014
Mouse
hindbrain morphogenesis GO:0021575 46 0.014
regulation of production of molecular mediator of immune response GO:0002700 65 0.014
positive regulation of response to wounding GO:1903036 66 0.014
Mouse
muscle cell differentiation GO:0042692 261 0.014
ureteric bud morphogenesis GO:0060675 62 0.014
anatomical structure homeostasis GO:0060249 145 0.014
metencephalon development GO:0022037 89 0.014
lymphocyte differentiation GO:0030098 242 0.014
regulation of fat cell differentiation GO:0045598 81 0.014
t cell activation GO:0042110 289 0.014
iron ion homeostasis GO:0055072 36 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.014
positive regulation of lymphocyte differentiation GO:0045621 61 0.014
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.014
renin angiotensin regulation of aldosterone production GO:0002018 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
positive regulation of macrophage activation GO:0043032 10 0.014
negative regulation of multi organism process GO:0043901 68 0.014
interspecies interaction between organisms GO:0044419 83 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
carbohydrate transport GO:0008643 62 0.014
organophosphate catabolic process GO:0046434 232 0.013
protein oligomerization GO:0051259 67 0.013
unsaturated fatty acid metabolic process GO:0033559 31 0.013
protein localization to nucleus GO:0034504 121 0.013
phosphatidylinositol mediated signaling GO:0048015 41 0.013
negative regulation of neuron death GO:1901215 98 0.013
positive regulation of proteolysis GO:0045862 85 0.013
gonad development GO:0008406 141 0.013
positive regulation of leukocyte proliferation GO:0070665 73 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
regulation of system process GO:0044057 200 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
divalent inorganic cation homeostasis GO:0072507 138 0.013
cytokine metabolic process GO:0042107 71 0.013
purine containing compound catabolic process GO:0072523 213 0.013
hepaticobiliary system development GO:0061008 67 0.013
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.013
negative regulation of response to wounding GO:1903035 77 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
methylation GO:0032259 134 0.013
negative regulation of carbohydrate metabolic process GO:0045912 19 0.013
positive regulation of type 2 immune response GO:0002830 9 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
antigen processing and presentation of peptide antigen GO:0048002 29 0.013
regulation of interleukin 6 production GO:0032675 55 0.012
regulation of peptide transport GO:0090087 91 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
cdc42 protein signal transduction GO:0032488 0 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of map kinase activity GO:0043405 120 0.012
wound healing GO:0042060 157 0.012
regulation of neuron death GO:1901214 134 0.012
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.012
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.012
regulation of triglyceride biosynthetic process GO:0010866 10 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
cellular response to glucocorticoid stimulus GO:0071385 13 0.012
lipid modification GO:0030258 65 0.012
protein ubiquitination GO:0016567 171 0.012
cellular response to drug GO:0035690 15 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
metanephric glomerular epithelium development GO:0072244 3 0.012
ossification GO:0001503 216 0.012
cerebellum morphogenesis GO:0021587 42 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.012
protein kinase b signaling GO:0043491 74 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
hexose transport GO:0008645 56 0.012
positive regulation of growth GO:0045927 104 0.012
female gamete generation GO:0007292 74 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of eosinophil migration GO:2000416 2 0.012
transition metal ion homeostasis GO:0055076 54 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
protein targeting GO:0006605 143 0.012
stress activated mapk cascade GO:0051403 80 0.012
regulation of multi organism process GO:0043900 111 0.012
leukocyte apoptotic process GO:0071887 71 0.012
mrna metabolic process GO:0016071 84 0.012
negative regulation of protein modification process GO:0031400 163 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
response to extracellular stimulus GO:0009991 127 0.012
anion transport GO:0006820 177 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
striated muscle cell development GO:0055002 125 0.012
female gonad development GO:0008585 71 0.012
nitric oxide biosynthetic process GO:0006809 25 0.012
regulation of dendritic cell dendrite assembly GO:2000547 2 0.011
negative regulation of growth GO:0045926 99 0.011
positive regulation of inflammatory response GO:0050729 47 0.011
Mouse
myeloid cell homeostasis GO:0002262 114 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
negative regulation of transferase activity GO:0051348 85 0.011
negative regulation of cell projection organization GO:0031345 56 0.011
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.011
regulation of protein kinase b signaling GO:0051896 56 0.011
positive regulation of apoptotic cell clearance GO:2000427 3 0.011
arginine transport GO:0015809 4 0.011
skeletal system development GO:0001501 356 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of innate immune response GO:0045088 91 0.011
fatty acid derivative metabolic process GO:1901568 33 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
regulation of immunoglobulin production GO:0002637 42 0.011
negative regulation of t cell activation GO:0050868 65 0.011
spermatid development GO:0007286 108 0.011
response to decreased oxygen levels GO:0036293 59 0.011
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.011
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011

C4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.107
disease of anatomical entity DOID:7 0 0.095
nervous system disease DOID:863 0 0.095
immune system disease DOID:2914 0 0.065
inherited metabolic disorder DOID:655 0 0.062
hematopoietic system disease DOID:74 0 0.055
hemolytic anemia DOID:583 0 0.054
hemolytic uremic syndrome DOID:12554 0 0.054
normocytic anemia DOID:720 0 0.054
anemia DOID:2355 0 0.054
retinal disease DOID:5679 0 0.050
retinal degeneration DOID:8466 0 0.050
sensory system disease DOID:0050155 0 0.050
eye and adnexa disease DOID:1492 0 0.050
eye disease DOID:5614 0 0.050
integumentary system disease DOID:16 0 0.021
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.013