IMP

Process View

Mus musculus

3 genes annotated in mouse

Multi-species View

intracellular cholesterol transport

GO:0032367

The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "intracellular cholesterol transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "intracellular cholesterol transport" (in gray)

Name	Description	Probability	Func Analog Organism
Npc1	Niemann Pick type C1	0.999
Apoe	apolipoprotein E	0.997
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.994	Human
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.900
Lrp1	low density lipoprotein receptor-related protein 1	0.890	Mouse
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.649
Sertad2	SERTA domain containing 2	0.414
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.344	Human
Axin1	axin 1	0.332
Tbx3	T-box 3	0.322
Pkd1	polycystic kidney disease 1 homolog	0.319
Smo	smoothened homolog (Drosophila)	0.274
Fgfr2	fibroblast growth factor receptor 2	0.253
Vangl2	vang-like 2 (van gogh, Drosophila)	0.231
Gsk3b	glycogen synthase kinase 3 beta	0.169
Fgfr3	fibroblast growth factor receptor 3	0.156
Mertk	c-mer proto-oncogene tyrosine kinase	0.156
Lrp5	low density lipoprotein receptor-related protein 5	0.155	Mouse
Ldlr	low density lipoprotein receptor	0.145
App	amyloid beta (A4) precursor protein	0.144
Fgfr1	fibroblast growth factor receptor 1	0.138
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.135
Ctnnb1	catenin (cadherin associated protein), beta 1	0.131
Pltp	phospholipid transfer protein	0.130
Pick1	protein interacting with C kinase 1	0.104
Gpr116	G protein-coupled receptor 116	0.099
Chuk	conserved helix-loop-helix ubiquitous kinase	0.078
Lyz2	lysozyme 2	0.068
Pofut1	protein O-fucosyltransferase 1	0.063
Atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.060
Mesdc2	mesoderm development candidate 2	0.060
Lrp6	low density lipoprotein receptor-related protein 6	0.057
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.053
Atp6v0e	ATPase, H+ transporting, lysosomal V0 subunit E	0.050
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.049
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.046
Crtc3	CREB regulated transcription coactivator 3	0.043
Notch2	Notch gene homolog 2 (Drosophila)	0.040
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.039
Lpin1	lipin 1	0.036
Agtr2	angiotensin II receptor, type 2	0.036
Lamp2	lysosomal-associated membrane protein 2	0.035
Bmp4	bone morphogenetic protein 4	0.035
Lrp4	low density lipoprotein receptor-related protein 4	0.035	Mouse
Pten	phosphatase and tensin homolog	0.035
Sepp1	selenoprotein P, plasma, 1	0.031
Plin1	perilipin 1	0.030
Ptp4a1	protein tyrosine phosphatase 4a1	0.030
Pparg	peroxisome proliferator activated receptor gamma	0.030
Clstn1	calsyntenin 1	0.030
Sacm1l	SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae)	0.029
Anpep	alanyl (membrane) aminopeptidase	0.027
Grn	granulin	0.027
Smad6	MAD homolog 6 (Drosophila)	0.027
Cav1	caveolin 1, caveolae protein	0.026
Psen1	presenilin 1	0.026
Fn1	fibronectin 1	0.026
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.025
Smad2	MAD homolog 2 (Drosophila)	0.025
C3	complement component 3	0.024
Man2a1	mannosidase 2, alpha 1	0.023
Tbk1	TANK-binding kinase 1	0.023
Scd1	stearoyl-Coenzyme A desaturase 1	0.023
Smagp	small cell adhesion glycoprotein	0.023
Runx2	runt related transcription factor 2	0.023
H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	0.023
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.022
Atp13a2	ATPase type 13A2	0.022
Cfh	complement component factor h	0.022
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.021
Htt	huntingtin	0.021
Slc6a20b	solute carrier family 6 (neurotransmitter transporter), member 20B	0.021
Tenc1	tensin like C1 domain-containing phosphatase	0.021
Rab9	RAB9, member RAS oncogene family	0.020
Gpx3	glutathione peroxidase 3	0.019
Hexa	hexosaminidase A	0.019
Cpne3	copine III	0.019
Cat	catalase	0.019
Pdgfb	platelet derived growth factor, B polypeptide	0.019
Ptprf	protein tyrosine phosphatase, receptor type, F	0.018
Tmem30a	transmembrane protein 30A	0.018
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.018
Tab1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.018
Sntg2	syntrophin, gamma 2	0.018
Irs2	insulin receptor substrate 2	0.018
Pros1	protein S (alpha)	0.018
Fndc3a	fibronectin type III domain containing 3A	0.017
Pcdh1	protocadherin 1	0.017
Slc33a1	solute carrier family 33 (acetyl-CoA transporter), member 1	0.017
Nfic	nuclear factor I/C	0.017
T	brachyury	0.017
Hadhb	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	0.017
Cxadr	coxsackie virus and adenovirus receptor	0.017
Mylip	myosin regulatory light chain interacting protein	0.016
Col4a3	collagen, type IV, alpha 3	0.016
Lgals3	lectin, galactose binding, soluble 3	0.016
Itga3	integrin alpha 3	0.016
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.016
Bmp1	bone morphogenetic protein 1	0.016
Rnf149	ring finger protein 149	0.016
Grb7	growth factor receptor bound protein 7	0.016
Gm2a	GM2 ganglioside activator protein	0.016
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.016
Ltbr	lymphotoxin B receptor	0.015
BC013529	cDNA sequence BC013529	0.015
Stab1	stabilin 1	0.015
Itgb2	integrin beta 2	0.015
Itgb5	integrin beta 5	0.015
Scarb1	scavenger receptor class B, member 1	0.015
Epas1	endothelial PAS domain protein 1	0.015
Rgs11	regulator of G-protein signaling 11	0.015
Phyh	phytanoyl-CoA hydroxylase	0.015
Idua	iduronidase, alpha-L-	0.015
Ghr	growth hormone receptor	0.015
C4b	complement component 4B (Childo blood group)	0.015
Adam9	a disintegrin and metallopeptidase domain 9 (meltrin gamma)	0.015
Klf15	Kruppel-like factor 15	0.014
Shh	sonic hedgehog	0.014
Il6st	interleukin 6 signal transducer	0.014
Lep	leptin	0.014
Mks1	Meckel syndrome, type 1	0.014
Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	0.014
Xylt2	xylosyltransferase II	0.014
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.014
Igfbp4	insulin-like growth factor binding protein 4	0.014
Kl	klotho	0.014
Ece1	endothelin converting enzyme 1	0.013
Apoa1	apolipoprotein A-I	0.013
Egfr	epidermal growth factor receptor	0.013
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.013
Naga	N-acetyl galactosaminidase, alpha	0.013
Man1a	mannosidase 1, alpha	0.013
Hspa5	heat shock protein 5	0.013
Lcat	lecithin cholesterol acyltransferase	0.013
Sox13	SRY-box containing gene 13	0.013
Tgfa	transforming growth factor alpha	0.013
Edem3	ER degradation enhancer, mannosidase alpha-like 3	0.013
Gaa	glucosidase, alpha, acid	0.013
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.013
Pet2	plasmacytoma expressed transcript 2	0.013
Lef1	lymphoid enhancer binding factor 1	0.013
Zfp185	zinc finger protein 185	0.013
Psap	prosaposin	0.013
Wls	wntless homolog (Drosophila)	0.013
Abhd5	abhydrolase domain containing 5	0.013
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.013
Rnase4	ribonuclease, RNase A family 4	0.012
Sgpl1	sphingosine phosphate lyase 1	0.012
Dlg4	discs, large homolog 4 (Drosophila)	0.012
Plin2	perilipin 2	0.012
Ndfip1	Nedd4 family interacting protein 1	0.012
Gns	glucosamine (N-acetyl)-6-sulfatase	0.012
Cldn6	claudin 6	0.012
Mcfd2	multiple coagulation factor deficiency 2	0.012
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.012
Tspo	translocator protein	0.012
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.012
D15Ertd621e	DNA segment, Chr 15, ERATO Doi 621, expressed	0.011
Acsl4	acyl-CoA synthetase long-chain family member 4	0.011
Folr1	folate receptor 1 (adult)	0.011
Llgl2	lethal giant larvae homolog 2 (Drosophila)	0.011
Ctage5	CTAGE family, member 5	0.011
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.011
Cdh1	cadherin 1	0.011
Lima1	LIM domain and actin binding 1	0.011
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.011
Tmem150a	transmembrane protein 150A	0.011
Dram2	VDNA-damage regulated autophagy modulator 2	0.011
Itm2b	integral membrane protein 2B	0.011
Col4a4	collagen, type IV, alpha 4	0.011
Miox	myo-inositol oxygenase	0.011
Sdcbp	syndecan binding protein	0.011
Bzw1	basic leucine zipper and W2 domains 1	0.011
Lamp1	lysosomal-associated membrane protein 1	0.011
Zfp865	zinc finger protein 865	0.011
Glg1	golgi apparatus protein 1	0.011
Rab5a	RAB5A, member RAS oncogene family	0.011
Atp6v1c1	ATPase, H+ transporting, lysosomal V1 subunit C1	0.011
Hiatl1	hippocampus abundant transcript-like 1	0.010
Osbpl8	oxysterol binding protein-like 8	0.010
Foxa2	forkhead box A2	0.010
Chpt1	choline phosphotransferase 1	0.010
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.010
Scarb2	scavenger receptor class B, member 2	0.010
Tep1	telomerase associated protein 1	0.010
Pls3	plastin 3 (T-isoform)	0.010
Mocs2	molybdenum cofactor synthesis 2	0.010
1500003O03Rik	RIKEN cDNA 1500003O03 gene	0.010
Ctsh	cathepsin H	0.010