Mus musculus

38 known processes

Slc12a1

solute carrier family 12, member 1

(Aliases: mBSC1,D630042G03Rik,Nkcc2,AI788571,urehr3)

Slc12a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
renal system process GO:0003014 48 0.999
hexose transmembrane transport GO:0035428 7 0.997
regulation of blood pressure GO:0008217 93 0.997
urogenital system development GO:0001655 261 0.994
response to osmotic stress GO:0006970 21 0.993
anion transport GO:0006820 177 0.993
anion transmembrane transport GO:0098656 71 0.993
kidney development GO:0001822 213 0.992
renin angiotensin regulation of aldosterone production GO:0002018 3 0.991
regulation of renal output by angiotensin GO:0002019 2 0.988
sodium ion transport GO:0006814 73 0.981
Mouse
l amino acid transport GO:0015807 32 0.979
hormone metabolic process GO:0042445 86 0.974
chloride transport GO:0006821 32 0.972
inorganic anion transport GO:0015698 43 0.970
regulation of systemic arterial blood pressure GO:0003073 61 0.963
cation transmembrane transport GO:0098655 266 0.963
positive regulation of blood pressure GO:0045777 21 0.962
inorganic ion transmembrane transport GO:0098660 234 0.953
cation transport GO:0006812 399 0.949
renal system development GO:0072001 225 0.945
response to organic cyclic compound GO:0014070 198 0.940
progesterone metabolic process GO:0042448 4 0.923
carnitine transmembrane transport GO:1902603 3 0.919
fat soluble vitamin catabolic process GO:0042363 1 0.903
c21 steroid hormone biosynthetic process GO:0006700 3 0.875
organic hydroxy compound metabolic process GO:1901615 203 0.868
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.844
spermatogenesis GO:0007283 284 0.838
inorganic cation transmembrane transport GO:0098662 207 0.835
circulatory system process GO:0003013 197 0.832
activation of janus kinase activity GO:0042976 2 0.822
transmembrane transport GO:0055085 412 0.819
monovalent inorganic cation homeostasis GO:0055067 33 0.815
urate transport GO:0015747 1 0.805
blood circulation GO:0008015 195 0.800
cellular response to peptide hormone stimulus GO:0071375 92 0.798
monoamine transport GO:0015844 33 0.797
renal sodium ion transport GO:0003096 2 0.797
response to peptide hormone GO:0043434 127 0.783
regulation of hormone levels GO:0010817 211 0.771
nephron epithelium development GO:0072009 92 0.770
amino acid transmembrane transport GO:0003333 37 0.767
amine metabolic process GO:0009308 45 0.765
drinking behavior GO:0042756 5 0.762
transmission of nerve impulse GO:0019226 76 0.719
cellular ketone metabolic process GO:0042180 84 0.718
positive regulation of systemic arterial blood pressure GO:0003084 9 0.717
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902238 1 0.708
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.704
organic hydroxy compound transport GO:0015850 93 0.698
inorganic anion transmembrane transport GO:0098661 29 0.698
potassium ion homeostasis GO:0055075 4 0.692
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.692
immune response in mucosal associated lymphoid tissue GO:0002386 2 0.691
nephron tubule development GO:0072080 84 0.690
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.662
vitamin d catabolic process GO:0042369 1 0.661
regulation of blood volume by renal aldosterone GO:0002017 1 0.653
negative regulation of phosphate metabolic process GO:0045936 184 0.650
cellular response to peptide GO:1901653 92 0.645
regulation of blood circulation GO:1903522 93 0.633
ion transmembrane transport GO:0034220 361 0.632
neurotransmitter uptake GO:0001504 14 0.630
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.628
metal ion homeostasis GO:0055065 189 0.626
potassium ion transmembrane transport GO:0071805 43 0.618
amino acid transport GO:0006865 61 0.611
response to alcohol GO:0097305 48 0.604
divalent metal ion transport GO:0070838 172 0.595
response to vitamin d GO:0033280 3 0.589
carboxylic acid transport GO:0046942 100 0.585
regulation of muscle system process GO:0090257 80 0.585
norepinephrine transport GO:0015874 2 0.582
response to nutrient levels GO:0031667 109 0.580
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 13 0.579
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1990127 1 0.579
histamine uptake GO:0051615 1 0.577
carbohydrate derivative biosynthetic process GO:1901137 183 0.572
response to peptide GO:1901652 136 0.571
organic anion transport GO:0015711 137 0.570
small molecule biosynthetic process GO:0044283 132 0.568
locomotory behavior GO:0007626 195 0.562
regulation of phospholipase a2 activity GO:0032429 3 0.560
small molecule catabolic process GO:0044282 71 0.559
renal tubule development GO:0061326 87 0.557
sodium ion homeostasis GO:0055078 7 0.551
nitrogen compound transport GO:0071705 271 0.551
visual perception GO:0007601 52 0.548
cellular response to extracellular stimulus GO:0031668 81 0.543
lipid biosynthetic process GO:0008610 179 0.542
feeding behavior GO:0007631 62 0.537
nephron development GO:0072006 109 0.533
purine containing compound biosynthetic process GO:0072522 70 0.517
glycosyl compound metabolic process GO:1901657 246 0.511
glucose transport GO:0015758 56 0.510
forebrain development GO:0030900 302 0.505
androgen biosynthetic process GO:0006702 4 0.505
cellular response to organonitrogen compound GO:0071417 145 0.501
cellular amine metabolic process GO:0044106 44 0.483
oxidation reduction process GO:0055114 342 0.482
cellular response to starvation GO:0009267 57 0.481
cellular response to abiotic stimulus GO:0071214 56 0.479
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator GO:1902239 1 0.476
cellular amino acid metabolic process GO:0006520 103 0.470
response to organonitrogen compound GO:0010243 246 0.464
regulation of cellular amine metabolic process GO:0033238 20 0.460
response to molecule of bacterial origin GO:0002237 143 0.457
mineralocorticoid biosynthetic process GO:0006705 1 0.454
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.453
male gamete generation GO:0048232 285 0.451
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger GO:0007199 1 0.447
gonad development GO:0008406 141 0.437
organic acid transport GO:0015849 101 0.434
carbohydrate transport GO:0008643 62 0.432
development of primary sexual characteristics GO:0045137 143 0.426
multicellular organismal signaling GO:0035637 91 0.420
kidney epithelium development GO:0072073 121 0.419
cation homeostasis GO:0055080 212 0.408
fat cell differentiation GO:0045444 160 0.404
negative regulation of blood pressure GO:0045776 22 0.397
purine ribonucleotide biosynthetic process GO:0009152 59 0.396
regulation of secretion GO:0051046 274 0.395
phenol containing compound metabolic process GO:0018958 60 0.394
neuronal action potential GO:0019228 54 0.386
action potential GO:0001508 78 0.380
morphogenesis of a branching epithelium GO:0061138 193 0.376
Mouse
divalent inorganic cation transport GO:0072511 178 0.375
response to corticosterone GO:0051412 1 0.375
sensory perception of light stimulus GO:0050953 54 0.374
cellular response to hormone stimulus GO:0032870 150 0.373
rhythmic process GO:0048511 174 0.371
response to lipopolysaccharide GO:0032496 128 0.370
body fluid secretion GO:0007589 53 0.370
histamine induced gastric acid secretion GO:0001697 1 0.361
cellular response to organic cyclic compound GO:0071407 87 0.350
transcytosis GO:0045056 5 0.349
carboxylic acid biosynthetic process GO:0046394 86 0.349
vitamin transport GO:0051180 10 0.339
steroid metabolic process GO:0008202 119 0.338
carbohydrate biosynthetic process GO:0016051 74 0.337
potassium ion transport GO:0006813 52 0.320
regulation of inward rectifier potassium channel activity GO:1901979 1 0.319
negative regulation of smooth muscle cell apoptotic process GO:0034392 1 0.313
organonitrogen compound biosynthetic process GO:1901566 192 0.306
monosaccharide transport GO:0015749 58 0.305
cellular response to lipid GO:0071396 145 0.303
nucleotide biosynthetic process GO:0009165 78 0.302
vitamin catabolic process GO:0009111 1 0.301
catecholamine transport GO:0051937 21 0.301
regulation of protein transport GO:0051223 163 0.298
c21 steroid hormone metabolic process GO:0008207 7 0.295
circadian rhythm GO:0007623 114 0.289
norepinephrine secretion GO:0048243 2 0.284
regulation of potassium ion transport GO:0043266 16 0.284
ovulation cycle GO:0042698 59 0.283
alpha amino acid catabolic process GO:1901606 18 0.280
l glutamate transport GO:0015813 16 0.274
cellular response to nutrient levels GO:0031669 64 0.271
nephron tubule morphogenesis GO:0072078 68 0.270
cell growth involved in cardiac muscle cell development GO:0061049 3 0.269
monocarboxylic acid metabolic process GO:0032787 191 0.260
sodium ion transmembrane transport GO:0035725 49 0.257
synaptic transmission GO:0007268 329 0.252
vitamin d3 metabolic process GO:0070640 3 0.252
neurotransmitter transport GO:0006836 76 0.248
digestion GO:0007586 40 0.247
fat soluble vitamin biosynthetic process GO:0042362 4 0.247
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.246
multi multicellular organism process GO:0044706 109 0.246
renal system process involved in regulation of blood volume GO:0001977 4 0.244
kidney morphogenesis GO:0060993 83 0.243
adult walking behavior GO:0007628 41 0.241
erk1 and erk2 cascade GO:0070371 77 0.238
water transport GO:0006833 12 0.237
ribonucleotide biosynthetic process GO:0009260 59 0.234
cellular potassium ion transport GO:0071804 43 0.232
central nervous system neuron differentiation GO:0021953 162 0.232
response to drug GO:0042493 75 0.231
sensory perception GO:0007600 245 0.229
Mouse
dicarboxylic acid transport GO:0006835 29 0.229
excretion GO:0007588 22 0.228
nucleobase containing small molecule metabolic process GO:0055086 352 0.226
hexose transport GO:0008645 56 0.220
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.219
branching morphogenesis of an epithelial tube GO:0048754 159 0.218
Mouse
regulation of resting membrane potential GO:0060075 3 0.218
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.216
morphogenesis of a branching structure GO:0001763 203 0.215
Mouse
hormone biosynthetic process GO:0042446 16 0.215
response to acid chemical GO:0001101 111 0.214
cellular homeostasis GO:0019725 240 0.213
positive regulation of programmed cell death GO:0043068 218 0.212
metanephric tubule development GO:0072170 18 0.212
regulation of membrane potential GO:0042391 192 0.212
endocrine process GO:0050886 39 0.212
l glutamate uptake involved in synaptic transmission GO:0051935 3 0.211
positive regulation of blood circulation GO:1903524 22 0.209
metanephric distal convoluted tubule development GO:0072221 5 0.208
regulation of body fluid levels GO:0050878 162 0.208
negative regulation of phosphorylation GO:0042326 166 0.208
carbohydrate metabolic process GO:0005975 230 0.207
regulation of camp mediated signaling GO:0043949 7 0.203
regulation of heart contraction GO:0008016 77 0.200
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.199
regulation of neurotransmitter levels GO:0001505 87 0.198
organophosphate biosynthetic process GO:0090407 122 0.196
regulation of angiotensin levels in blood GO:0002002 4 0.195
mesonephric tubule development GO:0072164 94 0.195
superoxide metabolic process GO:0006801 27 0.194
positive regulation of renal sodium excretion GO:0035815 2 0.193
organic hydroxy compound biosynthetic process GO:1901617 77 0.190
regulation of inflammatory response GO:0050727 147 0.190
regulation of ion transport GO:0043269 215 0.188
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.186
catecholamine secretion GO:0050432 15 0.185
cellular response to osmotic stress GO:0071470 7 0.184
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.184
calcitriol biosynthetic process from calciol GO:0036378 3 0.184
g protein coupled receptor signaling pathway GO:0007186 243 0.183
negative regulation of systemic arterial blood pressure GO:0003085 15 0.183
eye photoreceptor cell differentiation GO:0001754 41 0.183
alcohol metabolic process GO:0006066 116 0.182
negative regulation of heart rate GO:0010459 4 0.181
cellular response to steroid hormone stimulus GO:0071383 33 0.178
hexose metabolic process GO:0019318 98 0.176
renal sodium excretion GO:0035812 3 0.176
epithelial tube morphogenesis GO:0060562 303 0.175
Mouse
cellular response to insulin stimulus GO:0032869 78 0.173
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.172
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.170
aldosterone metabolic process GO:0032341 2 0.169
negative regulation of cellular protein metabolic process GO:0032269 247 0.168
distal tubule development GO:0072017 8 0.167
epithelial cell development GO:0002064 159 0.166
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.164
brain renin angiotensin system GO:0002035 5 0.161
regulation of catecholamine secretion GO:0050433 12 0.160
male sex differentiation GO:0046661 109 0.158
camera type eye development GO:0043010 266 0.158
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.158
regulation of neurotrophin trk receptor signaling pathway GO:0051386 4 0.157
fluid transport GO:0042044 14 0.154
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.154
peptidyl serine phosphorylation GO:0018105 74 0.154
axonogenesis GO:0007409 274 0.154
muscle contraction GO:0006936 101 0.154
second messenger mediated signaling GO:0019932 73 0.154
negative regulation of growth GO:0045926 99 0.153
cell cell adhesion GO:0098609 41 0.152
metanephric loop of henle development GO:0072236 4 0.151
steroid biosynthetic process GO:0006694 47 0.151
hydrogen ion transmembrane transport GO:1902600 25 0.151
negative regulation of ion transport GO:0043271 28 0.150
renal tubule morphogenesis GO:0061333 72 0.149
neurotrophin signaling pathway GO:0038179 12 0.149
peptide transport GO:0015833 133 0.149
regulation of reactive oxygen species metabolic process GO:2000377 40 0.148
aldosterone biosynthetic process GO:0032342 1 0.147
ensheathment of neurons GO:0007272 76 0.147
regulation of synaptic plasticity GO:0048167 87 0.145
neuropeptide signaling pathway GO:0007218 19 0.144
regulation of apoptotic signaling pathway GO:2001233 197 0.144
organic cyclic compound catabolic process GO:1901361 295 0.144
peptide hormone secretion GO:0030072 109 0.144
multicellular organism growth GO:0035264 161 0.143
Mouse
angiotensin activated signaling pathway GO:0038166 4 0.142
reactive oxygen species biosynthetic process GO:1903409 8 0.140
negative regulation of neurotrophin trk receptor signaling pathway GO:0051387 2 0.140
activation of adenylate cyclase activity GO:0007190 4 0.139
renal water homeostasis GO:0003091 7 0.139
metanephric nephron development GO:0072210 34 0.139
physiological cardiac muscle hypertrophy GO:0003301 3 0.138
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.138
camp biosynthetic process GO:0006171 31 0.137
regulation of the force of heart contraction GO:0002026 17 0.133
response to water deprivation GO:0009414 1 0.132
development of primary male sexual characteristics GO:0046546 88 0.132
response to oxidative stress GO:0006979 123 0.131
monosaccharide biosynthetic process GO:0046364 44 0.131
calcium ion transport GO:0006816 159 0.131
cellular response to monosaccharide stimulus GO:0071326 47 0.130
embryonic organ morphogenesis GO:0048562 276 0.129
hippocampus development GO:0021766 52 0.126
regulation of transferase activity GO:0051338 263 0.125
response to corticosteroid GO:0031960 20 0.125
dibenzo p dioxin metabolic process GO:0018894 1 0.124
glucocorticoid metabolic process GO:0008211 9 0.123
regulation of renal sodium excretion GO:0035813 3 0.122
cell adhesion GO:0007155 329 0.118
purine nucleotide biosynthetic process GO:0006164 65 0.118
dephosphorylation GO:0016311 129 0.118
mammary gland duct morphogenesis GO:0060603 38 0.116
Mouse
telencephalon development GO:0021537 186 0.116
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.116
inflammatory response GO:0006954 244 0.116
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.115
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.111
amino acid import into cell GO:1902837 4 0.111
regulation of tube size GO:0035150 57 0.110
regulation of neural precursor cell proliferation GO:2000177 70 0.110
cellular response to acid chemical GO:0071229 68 0.109
response to growth factor GO:0070848 198 0.108
gliogenesis GO:0042063 141 0.108
peptidyl serine modification GO:0018209 83 0.107
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.107
maternal process involved in female pregnancy GO:0060135 32 0.106
regulation of protein localization GO:0032880 231 0.106
regulation of neuronal synaptic plasticity GO:0048168 30 0.104
peptide hormone processing GO:0016486 9 0.103
cellular carbohydrate metabolic process GO:0044262 119 0.102
carbohydrate catabolic process GO:0016052 32 0.101
cellular response to gonadotropin stimulus GO:0071371 4 0.101
regulation of superoxide anion generation GO:0032928 4 0.100
response to monosaccharide GO:0034284 67 0.100
cellular response to external stimulus GO:0071496 88 0.100
amino acid betaine transport GO:0015838 3 0.099
response to extracellular stimulus GO:0009991 127 0.099
regulation of cholesterol esterification GO:0010872 2 0.099
reactive nitrogen species metabolic process GO:2001057 0 0.098
cellular response to carbohydrate stimulus GO:0071322 50 0.098
metanephros development GO:0001656 79 0.098
response to water GO:0009415 1 0.098
response to steroid hormone GO:0048545 56 0.097
regulation of steroid biosynthetic process GO:0050810 26 0.096
purine containing compound metabolic process GO:0072521 311 0.096
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.096
cellular divalent inorganic cation homeostasis GO:0072503 127 0.095
regulation of steroid metabolic process GO:0019218 39 0.095
glomerulus development GO:0032835 40 0.095
regulation of norepinephrine secretion GO:0014061 2 0.094
regulation of carbohydrate metabolic process GO:0006109 75 0.094
regulation of activation of jak2 kinase activity GO:0010534 1 0.093
intestinal absorption GO:0050892 13 0.093
thick ascending limb development GO:0072023 2 0.093
metanephric ascending thin limb development GO:0072218 2 0.092
organic acid biosynthetic process GO:0016053 86 0.092
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.091
regulation of ion transmembrane transporter activity GO:0032412 54 0.091
response to estrogen GO:0043627 24 0.090
nephron morphogenesis GO:0072028 69 0.090
ascending thin limb development GO:0072021 2 0.090
response to dexamethasone GO:0071548 8 0.090
hormone mediated signaling pathway GO:0009755 23 0.090
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.090
response to phenylpropanoid GO:0080184 22 0.088
forebrain neuron development GO:0021884 30 0.088
regulation of peptidyl serine phosphorylation GO:0033135 39 0.087
regulation of system process GO:0044057 200 0.087
brown fat cell differentiation GO:0050873 36 0.087
response to amino acid GO:0043200 37 0.087
dopamine receptor signaling pathway GO:0007212 16 0.086
grooming behavior GO:0007625 16 0.086
amino acid uptake involved in synaptic transmission GO:0051933 3 0.086
cellular chemical homeostasis GO:0055082 215 0.086
regulation of transmembrane transport GO:0034762 128 0.085
vasoconstriction GO:0042310 27 0.085
nucleotide metabolic process GO:0009117 332 0.085
nucleoside metabolic process GO:0009116 246 0.084
metanephric thick ascending limb development GO:0072233 2 0.083
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.083
metanephric proximal straight tubule development GO:0072230 1 0.083
ovulation GO:0030728 15 0.082
cellular response to corticosteroid stimulus GO:0071384 13 0.082
mesonephric tubule morphogenesis GO:0072171 63 0.081
acidic amino acid transport GO:0015800 16 0.081
chloride transmembrane transport GO:1902476 24 0.081
regulation of feeding behavior GO:0060259 3 0.080
l alpha amino acid transmembrane transport GO:1902475 23 0.080
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.080
regulation of gluconeogenesis GO:0006111 30 0.079
regulation of metal ion transport GO:0010959 106 0.079
limb development GO:0060173 166 0.079
mesonephric epithelium development GO:0072163 94 0.078
l glutamate import into cell GO:1990123 3 0.078
dopamine metabolic process GO:0042417 23 0.078
insulin receptor signaling pathway GO:0008286 49 0.078
peptide secretion GO:0002790 114 0.077
regulation of mapk cascade GO:0043408 248 0.077
regulation of anatomical structure size GO:0090066 178 0.077
nucleoside phosphate biosynthetic process GO:1901293 79 0.077
heart contraction GO:0060047 93 0.076
positive regulation of protein secretion GO:0050714 52 0.076
smooth muscle contraction GO:0006939 44 0.074
ribonucleoside metabolic process GO:0009119 245 0.074
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.074
regulation of ion homeostasis GO:2000021 64 0.074
cytokine production GO:0001816 319 0.073
reactive oxygen species metabolic process GO:0072593 84 0.073
cellular response to molecule of bacterial origin GO:0071219 83 0.072
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure GO:0002033 2 0.072
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.072
multicellular organismal homeostasis GO:0048871 164 0.072
steroid catabolic process GO:0006706 7 0.071
axon ensheathment GO:0008366 76 0.071
regulation of cellular ketone metabolic process GO:0010565 66 0.070
heart process GO:0003015 94 0.070
metanephric nephron tubule development GO:0072234 16 0.069
regulation of appetite GO:0032098 12 0.069
regulation of camp biosynthetic process GO:0030817 25 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.068
protein kinase c signaling GO:0070528 7 0.068
response to inorganic substance GO:0010035 96 0.068
cell proliferation in hindbrain GO:0021534 10 0.068
positive regulation of nervous system development GO:0051962 221 0.067
negative regulation of protein modification process GO:0031400 163 0.067
vitamin d biosynthetic process GO:0042368 3 0.067
multicellular organismal water homeostasis GO:0050891 23 0.067
regulation of secretion by cell GO:1903530 249 0.067
memory GO:0007613 58 0.066
midgut development GO:0007494 4 0.066
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 4 0.066
pallium development GO:0021543 120 0.066
metanephric nephron epithelium development GO:0072243 19 0.065
forebrain generation of neurons GO:0021872 63 0.065
metanephric epithelium development GO:0072207 21 0.065
regulation of establishment of protein localization GO:0070201 181 0.065
response to activity GO:0014823 13 0.065
apoptotic signaling pathway GO:0097190 306 0.064
regulation of protein secretion GO:0050708 82 0.064
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.064
ovulation from ovarian follicle GO:0001542 9 0.063
ribose phosphate biosynthetic process GO:0046390 59 0.063
regulation of peptide transport GO:0090087 91 0.062
cellular response to glucocorticoid stimulus GO:0071385 13 0.062
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.062
cellular response to vitamin d GO:0071305 2 0.062
regulation of serotonin uptake GO:0051611 2 0.061
progesterone biosynthetic process GO:0006701 1 0.061
cellular ion homeostasis GO:0006873 165 0.061
regulation of defense response GO:0031347 233 0.061
response to insulin GO:0032868 100 0.060
regulation of circadian sleep wake cycle GO:0042749 3 0.060
ribonucleotide metabolic process GO:0009259 291 0.060
cellular response to temperature stimulus GO:0071502 2 0.059
response to light stimulus GO:0009416 135 0.058
cyclic nucleotide biosynthetic process GO:0009190 44 0.058
purine nucleoside metabolic process GO:0042278 241 0.058
acid secretion GO:0046717 33 0.057
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.057
response to starvation GO:0042594 65 0.057
guanosine containing compound metabolic process GO:1901068 144 0.057
nephron epithelium morphogenesis GO:0072088 68 0.057
establishment of protein localization to organelle GO:0072594 118 0.056
regulation of ph GO:0006885 26 0.056
cellular response to fructose stimulus GO:0071332 2 0.056
regulation of kinase activity GO:0043549 249 0.056
cellular response to oxidative stress GO:0034599 76 0.055
regulation of ossification GO:0030278 112 0.055
establishment of blood nerve barrier GO:0008065 3 0.055
purine ribonucleoside metabolic process GO:0046128 241 0.055
positive regulation of mesonephros development GO:0061213 20 0.055
nucleoside phosphate catabolic process GO:1901292 222 0.054
cardiac muscle hypertrophy GO:0003300 23 0.054
negative regulation of muscle contraction GO:0045932 12 0.054
ureteric bud morphogenesis GO:0060675 62 0.054
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.054
exploration behavior GO:0035640 21 0.054
cellular response to ketone GO:1901655 12 0.053
ureteric bud development GO:0001657 94 0.053
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.053
cellular response to hexose stimulus GO:0071331 47 0.053
gastric acid secretion GO:0001696 6 0.052
photoreceptor cell differentiation GO:0046530 52 0.052
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.052
phospholipase c activating angiotensin activated signaling pathway GO:0086097 1 0.052
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.052
purine ribonucleotide metabolic process GO:0009150 290 0.051
adult behavior GO:0030534 135 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
development of primary female sexual characteristics GO:0046545 73 0.051
regulation of purine nucleotide metabolic process GO:1900542 169 0.051
monocarboxylic acid biosynthetic process GO:0072330 61 0.050
alcohol biosynthetic process GO:0046165 43 0.050
positive regulation of glycolytic process GO:0045821 4 0.050
phospholipase c activating dopamine receptor signaling pathway GO:0060158 5 0.050
catecholamine metabolic process GO:0006584 30 0.049
response to fructose GO:0009750 2 0.049
sensory perception of pain GO:0019233 47 0.049
regulation of peptide secretion GO:0002791 77 0.049
embryonic appendage morphogenesis GO:0035113 126 0.049
mineralocorticoid metabolic process GO:0008212 2 0.048
mesonephros development GO:0001823 97 0.047
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.047

Slc12a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.988
lipid metabolism disorder DOID:3146 0 0.988
inherited metabolic disorder DOID:655 0 0.988
steroid inherited metabolic disorder DOID:1701 0 0.988
congenital adrenal hyperplasia DOID:0050811 0 0.831
hypertension DOID:10763 0 0.763
artery disease DOID:0050828 0 0.763
disease of anatomical entity DOID:7 0 0.763
vascular disease DOID:178 0 0.763
essential hypertension DOID:10825 0 0.763
cardiovascular system disease DOID:1287 0 0.763
kidney disease DOID:557 0 0.119
urinary system disease DOID:18 0 0.119
renal tubular transport disease DOID:447 0 0.101
endocrine system disease DOID:28 0 0.095